FR2438036A1 - Derives d'acides iminocarboxyliques cycliques et medicament contenant ces substances - Google Patents
Derives d'acides iminocarboxyliques cycliques et medicament contenant ces substancesInfo
- Publication number
- FR2438036A1 FR2438036A1 FR7924683A FR7924683A FR2438036A1 FR 2438036 A1 FR2438036 A1 FR 2438036A1 FR 7924683 A FR7924683 A FR 7924683A FR 7924683 A FR7924683 A FR 7924683A FR 2438036 A1 FR2438036 A1 FR 2438036A1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- cyclic
- amino
- substances
- medicament containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
DERIVES D'ACIDES IMINOCARBOXYLIQUES CYCLIQUES. CES COMPOSES SONT CARACTERISES PAR LA FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE X ET X REPRESENTENT CHACUN L'HYDROGENE, UN HALOGENE, UN ALCOXY INFERIEUR, UN ALKYLE INFERIEUR OU UN GROUPE TRIFLUOROMETHYLE, NITRO, AMINO, ALKYLAMINO, ARALKYLAMINO, ACETYLAMINO OU ETHOXYCARBONYLAMINO, Y REPRESENTE -CO- OU -SO-, Z REPRESENTE -CH- OU -S- ET R L'HYDROGENE OU UN ALKYLE INFERIEUR. CES DERIVES AINSI QUE LEURS SELS, PEUVENT ETRE UTILISES COMME AGENTS ANTIHYPERTENSEURS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53123189A JPS5829950B2 (ja) | 1978-10-05 | 1978-10-05 | 環状イミノカルボン酸誘導体およびその塩類 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2438036A1 true FR2438036A1 (fr) | 1980-04-30 |
FR2438036B1 FR2438036B1 (fr) | 1983-03-18 |
Family
ID=14854386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7924683A Granted FR2438036A1 (fr) | 1978-10-05 | 1979-10-04 | Derives d'acides iminocarboxyliques cycliques et medicament contenant ces substances |
Country Status (10)
Country | Link |
---|---|
US (1) | US4450275A (fr) |
JP (1) | JPS5829950B2 (fr) |
BE (1) | BE879158A (fr) |
ES (1) | ES484679A1 (fr) |
FR (1) | FR2438036A1 (fr) |
GB (1) | GB2045249B (fr) |
IT (1) | IT1121045B (fr) |
NL (1) | NL7920076A (fr) |
SE (1) | SE434264B (fr) |
WO (1) | WO1980000700A1 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2440365A1 (fr) * | 1978-10-31 | 1980-05-30 | Santen Pharmaceutical Co Ltd | Nouveaux derives d'acides mercapto-azolidine-carboxyliques utiles comme hypertenseurs |
EP0067885A1 (fr) * | 1980-12-29 | 1982-12-29 | Santen Pharmaceutical Co., Ltd. | Composes comprenant des heterocycles a 5 branches |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4312990A (en) | 1980-09-11 | 1982-01-26 | E. R. Squibb & Sons, Inc. | 1-Mercaptoacyl-3-[(aminosulfonyl) phenyl]-4,5-dihydro-1H-pyrazole-5-carboxylic acid |
US4312809A (en) | 1980-10-31 | 1982-01-26 | E. R. Squibb & Sons, Inc. | Lactam derivatives of mercaptoacylamino acids |
US4681886A (en) * | 1982-04-30 | 1987-07-21 | E. R. Squibb & Sons, Inc. | Substituted 4-phenoxy or 4-phenylthio prolines |
US4661515A (en) * | 1982-07-21 | 1987-04-28 | Usv Pharmaceutical Corporation | Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity |
JPS6090152U (ja) * | 1983-11-28 | 1985-06-20 | 株式会社吉野工業所 | 液体注出容器 |
US4536501A (en) * | 1984-03-30 | 1985-08-20 | E. R. Squibb & Sons, Inc. | Substituted 4-phenoxy or 4-phenylthio prolines |
EP0190852A3 (fr) * | 1985-01-31 | 1988-11-02 | Ajinomoto Co., Inc. | Dérivés dipeptides et les médicaments antihypertensifs les contenant |
US7056935B2 (en) | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
DE10115938A1 (de) * | 2001-03-30 | 2002-10-10 | Medigene Ag Ges Fuer Molekular | Verfahren zur Herstellung von Oxirancarbonsäuren und Derivaten davon |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
FR2372817A1 (fr) * | 1976-12-03 | 1978-06-30 | Squibb & Sons Inc | Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension |
FR2383171A1 (fr) * | 1977-03-11 | 1978-10-06 | Squibb & Sons Inc | Derives de thiopropanoylaminoacides utiles comme hypotenseurs |
FR2407204A1 (fr) * | 1977-10-28 | 1979-05-25 | Sandoz Sa | Nouveaux amides d'amino-acides cycliques, leur preparation et leur application comme medicaments |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4192878A (en) * | 1976-12-03 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
FR2404635A1 (fr) * | 1977-09-28 | 1979-04-27 | Science Union & Cie | Nouveaux thioproprionylamides, leurs procedures d'obtention et leur emploi en therapeutique |
CA1120400A (fr) * | 1977-12-27 | 1982-03-23 | Zola P. Horovitz | Traitement de l'hypertension et medicaments utilises a cette fin |
US4282235A (en) * | 1978-05-22 | 1981-08-04 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
-
1978
- 1978-10-05 JP JP53123189A patent/JPS5829950B2/ja not_active Expired
-
1979
- 1979-09-28 GB GB8017628A patent/GB2045249B/en not_active Expired
- 1979-09-28 NL NL7920076A patent/NL7920076A/nl not_active Application Discontinuation
- 1979-09-28 WO PCT/JP1979/000249 patent/WO1980000700A1/fr unknown
- 1979-10-03 BE BE2/58115A patent/BE879158A/fr not_active IP Right Cessation
- 1979-10-03 ES ES484679A patent/ES484679A1/es not_active Expired
- 1979-10-04 IT IT68916/79A patent/IT1121045B/it active
- 1979-10-04 FR FR7924683A patent/FR2438036A1/fr active Granted
-
1980
- 1980-06-04 SE SE8004166A patent/SE434264B/sv unknown
- 1980-09-28 US US06/227,104 patent/US4450275A/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
FR2372817A1 (fr) * | 1976-12-03 | 1978-06-30 | Squibb & Sons Inc | Derives d'acides thiazolidinecarboxyliques et d'acides apparentes, utiles comme agents anti-hypertension |
FR2383171A1 (fr) * | 1977-03-11 | 1978-10-06 | Squibb & Sons Inc | Derives de thiopropanoylaminoacides utiles comme hypotenseurs |
FR2407204A1 (fr) * | 1977-10-28 | 1979-05-25 | Sandoz Sa | Nouveaux amides d'amino-acides cycliques, leur preparation et leur application comme medicaments |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2440365A1 (fr) * | 1978-10-31 | 1980-05-30 | Santen Pharmaceutical Co Ltd | Nouveaux derives d'acides mercapto-azolidine-carboxyliques utiles comme hypertenseurs |
EP0067885A1 (fr) * | 1980-12-29 | 1982-12-29 | Santen Pharmaceutical Co., Ltd. | Composes comprenant des heterocycles a 5 branches |
EP0067885A4 (fr) * | 1980-12-29 | 1983-04-18 | Santen Pharmaceutical Co Ltd | Composes comprenant des heterocycles a 5 branches. |
US4464371A (en) * | 1980-12-29 | 1984-08-07 | Santen Pharmaceutical Co., Ltd. | Five-membered heterocyclic compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS5829950B2 (ja) | 1983-06-25 |
US4450275A (en) | 1984-05-22 |
WO1980000700A1 (fr) | 1980-04-17 |
SE434264B (sv) | 1984-07-16 |
NL7920076A (nl) | 1980-08-29 |
SE8004166L (sv) | 1980-06-04 |
IT7968916A0 (it) | 1979-10-04 |
GB2045249B (en) | 1983-01-26 |
BE879158A (fr) | 1980-02-01 |
JPS5549352A (en) | 1980-04-09 |
FR2438036B1 (fr) | 1983-03-18 |
IT1121045B (it) | 1986-03-26 |
GB2045249A (en) | 1980-10-29 |
ES484679A1 (es) | 1980-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |