SE434264B - Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel - Google Patents
Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medelInfo
- Publication number
- SE434264B SE434264B SE8004166A SE8004166A SE434264B SE 434264 B SE434264 B SE 434264B SE 8004166 A SE8004166 A SE 8004166A SE 8004166 A SE8004166 A SE 8004166A SE 434264 B SE434264 B SE 434264B
- Authority
- SE
- Sweden
- Prior art keywords
- acid
- proline
- chloro
- formula
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53123189A JPS5829950B2 (ja) | 1978-10-05 | 1978-10-05 | 環状イミノカルボン酸誘導体およびその塩類 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8004166L SE8004166L (sv) | 1980-06-04 |
SE434264B true SE434264B (sv) | 1984-07-16 |
Family
ID=14854386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8004166A SE434264B (sv) | 1978-10-05 | 1980-06-04 | Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel |
Country Status (10)
Country | Link |
---|---|
US (1) | US4450275A (fr) |
JP (1) | JPS5829950B2 (fr) |
BE (1) | BE879158A (fr) |
ES (1) | ES484679A1 (fr) |
FR (1) | FR2438036A1 (fr) |
GB (1) | GB2045249B (fr) |
IT (1) | IT1121045B (fr) |
NL (1) | NL7920076A (fr) |
SE (1) | SE434264B (fr) |
WO (1) | WO1980000700A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4483861A (en) * | 1978-10-31 | 1984-11-20 | Santen Pharmaceutical Co., Ltd. | Antihypertensive sulfur-containing compounds |
US4312990A (en) | 1980-09-11 | 1982-01-26 | E. R. Squibb & Sons, Inc. | 1-Mercaptoacyl-3-[(aminosulfonyl) phenyl]-4,5-dihydro-1H-pyrazole-5-carboxylic acid |
US4312809A (en) | 1980-10-31 | 1982-01-26 | E. R. Squibb & Sons, Inc. | Lactam derivatives of mercaptoacylamino acids |
JPS57112381A (en) * | 1980-12-29 | 1982-07-13 | Santen Pharmaceut Co Ltd | Five-membered heterocyclic compound |
US4681886A (en) * | 1982-04-30 | 1987-07-21 | E. R. Squibb & Sons, Inc. | Substituted 4-phenoxy or 4-phenylthio prolines |
US4661515A (en) * | 1982-07-21 | 1987-04-28 | Usv Pharmaceutical Corporation | Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity |
JPS6090152U (ja) * | 1983-11-28 | 1985-06-20 | 株式会社吉野工業所 | 液体注出容器 |
US4536501A (en) * | 1984-03-30 | 1985-08-20 | E. R. Squibb & Sons, Inc. | Substituted 4-phenoxy or 4-phenylthio prolines |
EP0190852A3 (fr) * | 1985-01-31 | 1988-11-02 | Ajinomoto Co., Inc. | Dérivés dipeptides et les médicaments antihypertensifs les contenant |
US7056935B2 (en) | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
DE10115938A1 (de) * | 2001-03-30 | 2002-10-10 | Medigene Ag Ges Fuer Molekular | Verfahren zur Herstellung von Oxirancarbonsäuren und Derivaten davon |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4105776A (en) * | 1976-06-21 | 1978-08-08 | E. R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
AU518147B2 (en) * | 1976-12-03 | 1981-09-17 | E.R. Squibb & Sons, Inc. | Derivatives of thiazolidine, thiazine and morpholine carboxylic acids |
US4192878A (en) * | 1976-12-03 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
FR2404635A1 (fr) * | 1977-09-28 | 1979-04-27 | Science Union & Cie | Nouveaux thioproprionylamides, leurs procedures d'obtention et leur emploi en therapeutique |
IT7851510A0 (it) * | 1977-10-28 | 1978-10-16 | Sandoz Ag | Ammidi di amminoacidi ciclici loro preparazione e loro applicazione quali medicamenti |
CA1120400A (fr) * | 1977-12-27 | 1982-03-23 | Zola P. Horovitz | Traitement de l'hypertension et medicaments utilises a cette fin |
US4282235A (en) * | 1978-05-22 | 1981-08-04 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
-
1978
- 1978-10-05 JP JP53123189A patent/JPS5829950B2/ja not_active Expired
-
1979
- 1979-09-28 WO PCT/JP1979/000249 patent/WO1980000700A1/fr unknown
- 1979-09-28 GB GB8017628A patent/GB2045249B/en not_active Expired
- 1979-09-28 NL NL7920076A patent/NL7920076A/nl not_active Application Discontinuation
- 1979-10-03 BE BE2/58115A patent/BE879158A/fr not_active IP Right Cessation
- 1979-10-03 ES ES484679A patent/ES484679A1/es not_active Expired
- 1979-10-04 IT IT68916/79A patent/IT1121045B/it active
- 1979-10-04 FR FR7924683A patent/FR2438036A1/fr active Granted
-
1980
- 1980-06-04 SE SE8004166A patent/SE434264B/sv unknown
- 1980-09-28 US US06/227,104 patent/US4450275A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
SE8004166L (sv) | 1980-06-04 |
JPS5549352A (en) | 1980-04-09 |
US4450275A (en) | 1984-05-22 |
GB2045249A (en) | 1980-10-29 |
BE879158A (fr) | 1980-02-01 |
GB2045249B (en) | 1983-01-26 |
ES484679A1 (es) | 1980-05-16 |
IT7968916A0 (it) | 1979-10-04 |
NL7920076A (nl) | 1980-08-29 |
IT1121045B (it) | 1986-03-26 |
FR2438036B1 (fr) | 1983-03-18 |
FR2438036A1 (fr) | 1980-04-30 |
WO1980000700A1 (fr) | 1980-04-17 |
JPS5829950B2 (ja) | 1983-06-25 |
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