SE434264B - Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel - Google Patents

Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel

Info

Publication number
SE434264B
SE434264B SE8004166A SE8004166A SE434264B SE 434264 B SE434264 B SE 434264B SE 8004166 A SE8004166 A SE 8004166A SE 8004166 A SE8004166 A SE 8004166A SE 434264 B SE434264 B SE 434264B
Authority
SE
Sweden
Prior art keywords
acid
proline
chloro
formula
salt
Prior art date
Application number
SE8004166A
Other languages
English (en)
Swedish (sv)
Other versions
SE8004166L (sv
Inventor
K Arimura
S Murakami
T Oka
Original Assignee
Yoshitomi Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical filed Critical Yoshitomi Pharmaceutical
Publication of SE8004166L publication Critical patent/SE8004166L/xx
Publication of SE434264B publication Critical patent/SE434264B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8004166A 1978-10-05 1980-06-04 Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel SE434264B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53123189A JPS5829950B2 (ja) 1978-10-05 1978-10-05 環状イミノカルボン酸誘導体およびその塩類

Publications (2)

Publication Number Publication Date
SE8004166L SE8004166L (sv) 1980-06-04
SE434264B true SE434264B (sv) 1984-07-16

Family

ID=14854386

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8004166A SE434264B (sv) 1978-10-05 1980-06-04 Nya derivat av prolin och tiazolidin anvendbara som antihypertensiva medel

Country Status (10)

Country Link
US (1) US4450275A (fr)
JP (1) JPS5829950B2 (fr)
BE (1) BE879158A (fr)
ES (1) ES484679A1 (fr)
FR (1) FR2438036A1 (fr)
GB (1) GB2045249B (fr)
IT (1) IT1121045B (fr)
NL (1) NL7920076A (fr)
SE (1) SE434264B (fr)
WO (1) WO1980000700A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
US4312990A (en) 1980-09-11 1982-01-26 E. R. Squibb & Sons, Inc. 1-Mercaptoacyl-3-[(aminosulfonyl) phenyl]-4,5-dihydro-1H-pyrazole-5-carboxylic acid
US4312809A (en) 1980-10-31 1982-01-26 E. R. Squibb & Sons, Inc. Lactam derivatives of mercaptoacylamino acids
JPS57112381A (en) * 1980-12-29 1982-07-13 Santen Pharmaceut Co Ltd Five-membered heterocyclic compound
US4681886A (en) * 1982-04-30 1987-07-21 E. R. Squibb & Sons, Inc. Substituted 4-phenoxy or 4-phenylthio prolines
US4661515A (en) * 1982-07-21 1987-04-28 Usv Pharmaceutical Corporation Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity
JPS6090152U (ja) * 1983-11-28 1985-06-20 株式会社吉野工業所 液体注出容器
US4536501A (en) * 1984-03-30 1985-08-20 E. R. Squibb & Sons, Inc. Substituted 4-phenoxy or 4-phenylthio prolines
EP0190852A3 (fr) * 1985-01-31 1988-11-02 Ajinomoto Co., Inc. Dérivés dipeptides et les médicaments antihypertensifs les contenant
US7056935B2 (en) 1995-06-07 2006-06-06 Gpi Nil Holdings, Inc. Rotamase enzyme activity inhibitors
DE10115938A1 (de) * 2001-03-30 2002-10-10 Medigene Ag Ges Fuer Molekular Verfahren zur Herstellung von Oxirancarbonsäuren und Derivaten davon

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
AU518147B2 (en) * 1976-12-03 1981-09-17 E.R. Squibb & Sons, Inc. Derivatives of thiazolidine, thiazine and morpholine carboxylic acids
US4192878A (en) * 1976-12-03 1980-03-11 E. R. Squibb & Sons, Inc. Derivatives of thiazolidinecarboxylic acids and related acids
US4108886A (en) * 1977-03-11 1978-08-22 E. R. Squibb & Sons, Inc. Thiopropanoylamino acid derivatives
FR2404635A1 (fr) * 1977-09-28 1979-04-27 Science Union & Cie Nouveaux thioproprionylamides, leurs procedures d'obtention et leur emploi en therapeutique
IT7851510A0 (it) * 1977-10-28 1978-10-16 Sandoz Ag Ammidi di amminoacidi ciclici loro preparazione e loro applicazione quali medicamenti
CA1120400A (fr) * 1977-12-27 1982-03-23 Zola P. Horovitz Traitement de l'hypertension et medicaments utilises a cette fin
US4282235A (en) * 1978-05-22 1981-08-04 E. R. Squibb & Sons, Inc. Derivatives of thiazolidinecarboxylic acids and related acids

Also Published As

Publication number Publication date
SE8004166L (sv) 1980-06-04
JPS5549352A (en) 1980-04-09
US4450275A (en) 1984-05-22
GB2045249A (en) 1980-10-29
BE879158A (fr) 1980-02-01
GB2045249B (en) 1983-01-26
ES484679A1 (es) 1980-05-16
IT7968916A0 (it) 1979-10-04
NL7920076A (nl) 1980-08-29
IT1121045B (it) 1986-03-26
FR2438036B1 (fr) 1983-03-18
FR2438036A1 (fr) 1980-04-30
WO1980000700A1 (fr) 1980-04-17
JPS5829950B2 (ja) 1983-06-25

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