FR2413358A1 - Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation - Google Patents
Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparationInfo
- Publication number
- FR2413358A1 FR2413358A1 FR7836910A FR7836910A FR2413358A1 FR 2413358 A1 FR2413358 A1 FR 2413358A1 FR 7836910 A FR7836910 A FR 7836910A FR 7836910 A FR7836910 A FR 7836910A FR 2413358 A1 FR2413358 A1 FR 2413358A1
- Authority
- FR
- France
- Prior art keywords
- useful
- new
- preparation process
- inflammatory agents
- aminomethylphenol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LES MEDICAMENTS SELON L'INVENTION SONT DES 2-AMINOMETHYLPHENOLS DE FORMULE GENERALE: (CF DESSIN DANS BOPI) DANS LAQUELLE X EST UN ATOME D'HALOGENE, R, R, R ET R SONT IDENTIQUES OU DIFFERENTS ET REPRESENTENT CHACUN UN ATOME D'HYDROGENE OU UN GROUPE ALKYLE A CHAINE DROITE OU RAMIFIEE EN C-C ET N EST EGAL A 2, 3, 4 OU 5; ET LEURS SELS D'ADDITION D'ACIDES ACCEPTABLES EN PHARMACIE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52158737A JPS6049183B2 (ja) | 1977-12-29 | 1977-12-29 | 2−アミノメチルフェノ−ル誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2413358A1 true FR2413358A1 (fr) | 1979-07-27 |
FR2413358B1 FR2413358B1 (fr) | 1983-04-15 |
Family
ID=15678224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7836910A Granted FR2413358A1 (fr) | 1977-12-29 | 1978-12-29 | Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation |
Country Status (6)
Country | Link |
---|---|
US (1) | US4254056A (fr) |
JP (1) | JPS6049183B2 (fr) |
DE (1) | DE2855064C2 (fr) |
FR (1) | FR2413358A1 (fr) |
GB (1) | GB2013655B (fr) |
IT (1) | IT1109400B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002012A1 (fr) * | 1980-01-14 | 1981-07-23 | Sandoz Ag | Nouveaux 2-amino methyl - 6 - halogenophenols, leur preparation et leurs compositions pharmaceutiques |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ193729A (en) * | 1979-05-28 | 1982-03-30 | Ciba Geigy Ag | Substituted phenols medicinal preparations |
US4430319A (en) | 1982-05-21 | 1984-02-07 | State University Of New York | Radioactive iodine labeled phenolic amines |
ZA885824B (en) * | 1987-08-14 | 1989-04-26 | Merrell Dow Pharma | Novel antidepressants |
US5149714A (en) * | 1987-08-14 | 1992-09-22 | Merrell Dow Pharmaceuticals Inc. | Antidepressants |
US6495496B2 (en) * | 2000-12-22 | 2002-12-17 | Infineum International Ltd. | Hydroxy aromatic mannich base condensation products and the use thereof as soot dispersants in lubricating oil compositions |
US20150272666A1 (en) * | 2012-11-02 | 2015-10-01 | Lixiao Wang | Chemical Ablation Formulations and Methods of Treatments for Various Diseases |
EP3212274A4 (fr) | 2014-10-30 | 2018-06-27 | Neurotronic, Inc. | Ablation chimique et méthodes destinées à traiter diverses maladies |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE541651A (fr) * | ||||
US3809721A (en) * | 1970-12-23 | 1974-05-07 | Merck & Co Inc | Substituted 2-aminomethyl-4,6-disubstituted phenols |
FR2261754A1 (en) * | 1974-02-22 | 1975-09-19 | Merck & Co Inc | 4,6-Disubstd-2-aminomethyl phenols - as antiinflammatory, diuretic and salidiuretic agents |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3072716A (en) * | 1959-03-18 | 1963-01-08 | Ciba Geigy Corp | Substituted indenes |
US3504031A (en) * | 1966-05-24 | 1970-03-31 | Mead Johnson & Co | 1-aminoalkyl-1-phenylindene process and intermediate therefor |
US3642785A (en) * | 1969-08-11 | 1972-02-15 | Merck & Co Inc | Indenyl-3-aliphatic amines |
US3830854A (en) * | 1970-01-08 | 1974-08-20 | Allied Chem | Substituted 5,8-dimethyl-5,6,7,8-tetrahydro-1-naphthols |
US3845063A (en) * | 1970-12-28 | 1974-10-29 | Dow Chemical Co | Preparation of symmetrical 4-(dialkylamino)phenols |
US3794734A (en) * | 1971-03-03 | 1974-02-26 | Merck & Co Inc | Methods of treating edema and hypertension using certain 2-aminoethylphenols |
CA1017359A (en) * | 1972-07-03 | 1977-09-13 | Frederic P. Hauck | Substituted cyclic polymethylene phenols |
US4005093A (en) * | 1975-01-20 | 1977-01-25 | Sterling Drug Inc. | 2-Naphthyl-lower-alkylamines |
-
1977
- 1977-12-29 JP JP52158737A patent/JPS6049183B2/ja not_active Expired
-
1978
- 1978-12-20 DE DE2855064A patent/DE2855064C2/de not_active Expired
- 1978-12-27 GB GB7850007A patent/GB2013655B/en not_active Expired
- 1978-12-28 IT IT52471/78A patent/IT1109400B/it active
- 1978-12-28 US US05/974,179 patent/US4254056A/en not_active Expired - Lifetime
- 1978-12-29 FR FR7836910A patent/FR2413358A1/fr active Granted
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE541651A (fr) * | ||||
US3809721A (en) * | 1970-12-23 | 1974-05-07 | Merck & Co Inc | Substituted 2-aminomethyl-4,6-disubstituted phenols |
FR2261754A1 (en) * | 1974-02-22 | 1975-09-19 | Merck & Co Inc | 4,6-Disubstd-2-aminomethyl phenols - as antiinflammatory, diuretic and salidiuretic agents |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1981002012A1 (fr) * | 1980-01-14 | 1981-07-23 | Sandoz Ag | Nouveaux 2-amino methyl - 6 - halogenophenols, leur preparation et leurs compositions pharmaceutiques |
Also Published As
Publication number | Publication date |
---|---|
JPS6049183B2 (ja) | 1985-10-31 |
IT1109400B (it) | 1985-12-16 |
GB2013655B (en) | 1982-02-24 |
DE2855064C2 (de) | 1986-08-28 |
DE2855064A1 (de) | 1979-07-12 |
GB2013655A (en) | 1979-08-15 |
FR2413358B1 (fr) | 1983-04-15 |
JPS5492946A (en) | 1979-07-23 |
US4254056A (en) | 1981-03-03 |
IT7852471A0 (it) | 1978-12-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2360587A1 (fr) | Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments | |
FR2370731A1 (fr) | Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique | |
FR2453853A1 (fr) | Nouveaux derives d'o-(4-diphenylmethylpiperidino)-alcanophenones utiles notamment comme antihistaminiques, et leur procede de preparation | |
FR2378521A1 (fr) | Derives du carbostyrile, utiles notamment comme stimulants des centres b- adrenorecepteurs, et leur procede de preparation | |
ES8107185A1 (es) | Procedimiento para preparar piperidinas y pirrolidinas sus- tituidas | |
FR2392971A1 (fr) | Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances | |
BE901545A (fr) | Nouveaux derives de la furo-(3,4-c)-pyridine substitues en position 6, un procede pour leur preparation et compositions therapeutiques a base de ces derives. | |
AU6791781A (en) | Piperazino phenylindane | |
FR2361901A1 (fr) | Derives de substitution de nucleotides et medicament contenant ces substances | |
FR2436786A1 (fr) | Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments | |
FR2447376A1 (fr) | Nouveaux derives de 1,2-dihydro-2-oxo-4-phenyl-3-quinoleinecarbonitrile, utiles notamment comme agents anti-inflammatoires | |
FR2448531A1 (fr) | Nouveaux derives de 4-(naphtylmethyl)piperidine, utiles notamment comme agents antipsychotiques et leur procede de preparation | |
BE905110A (fr) | Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques. | |
FR2394546A1 (fr) | Nouveaux derives de 1,2,3,4,6,7-hexahydro-11bah-benzo(a)-quinolizine, leur preparation et leur application en tant que medicaments | |
FR2413358A1 (fr) | Nouveaux derives de 2-aminomethylphenol, utiles notamment comme agents anti-inflammatoires, et leur procede de preparation | |
FR2453866A1 (fr) | Derives peptidiques, procede pour leur preparation et leur application dans des preparations pharmaceutiques | |
FR2450820A1 (fr) | Nouveaux derives d'acides 1- (o-mercaptoacyl) -4,5-dihydropyrazole-5-carboxyliques, utiles notamment comme agents hypotenseurs, et leur procede de preparation | |
FR2362845A1 (fr) | Nouveaux derives de o-(3-amino-2-hydroxy-propyl)-amidoxime, procede pour leur preparation et compositions pharmaceutiques les contenant | |
FR2452483A1 (fr) | Derives d'alcenylphenylmaleimides, leurs dimeres lineaires et leur procede de preparation | |
FR2367750A1 (fr) | Acid | |
ATE72447T1 (de) | Chartreusinderivate und salze, diese enthaltende antitumorzusammensetzungen und verfahren zu ihrer herstellung. | |
FI920425A0 (fi) | Cykloalkylenazoler, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat och deras anvaendning vid framstaellning av laekemedel. | |
FR2422638A1 (fr) | Nouveaux derives de 3,3-dichloro-2-azetidinone, utiles notamment comme agents anti-inflammatoires | |
FR2421181A1 (fr) | Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant | |
FR2420975A1 (fr) | Medicaments anticomplementaires en partie antinephretiques, de type soyasapogenol b et leur procede de preparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |