FI911952A0 - Uudet, 4-substituoidut antrasyklinonit ja antrasykliiniglykosidit ja menetelmä niiden valmistamiseksi - Google Patents

Uudet, 4-substituoidut antrasyklinonit ja antrasykliiniglykosidit ja menetelmä niiden valmistamiseksi

Info

Publication number: FI911952A0
Authority: FI; Finland
Prior art keywords: group; substituted; preparation; new; anthracycline glycosides
Prior art date: 1988-10-25

Application number

FI911952A

Other languages

English (en)

Swedish (sv)

Other versions

FI93364B (fi

FI93364C (fi

Inventor

Walter Cabri

Bernardinis Silvia De

Franco Francalanci

Sergio Penco

Original Assignee

Erba Carlo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-25

Filing date

1991-04-22

Publication date

1991-04-22

1991-04-22 Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa

1991-04-22 Publication of FI911952A0 publication Critical patent/FI911952A0/fi

1994-12-15 Publication of FI93364B publication Critical patent/FI93364B/fi

1995-03-27 Application granted granted Critical

1995-03-27 Publication of FI93364C publication Critical patent/FI93364C/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI911952A 1988-10-25 1991-04-22 Uudet, 4-substituoidut antrasyklinonit ja antrasykliiniglykosidit ja menetelmä niiden valmistamiseksi FI93364C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB8824947		1988-10-25
GB888824947A GB8824947D0 (en)	1988-10-25	1988-10-25	New 4-substituted anthracyclinones & process for preparing them
PCT/EP1989/001266 WO1990004601A1 (en)	1988-10-25	1989-10-24	New 4-substituted anthracyclinones and anthracycline glycosides and the process for preparing them
EP8901266		1989-10-24

Publications (3)

Publication Number	Publication Date
FI911952A0 true FI911952A0 (fi)	1991-04-22
FI93364B FI93364B (fi)	1994-12-15
FI93364C FI93364C (fi)	1995-03-27

Family

ID=10645743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI911952A FI93364C (fi)	1988-10-25	1991-04-22	Uudet, 4-substituoidut antrasyklinonit ja antrasykliiniglykosidit ja menetelmä niiden valmistamiseksi

Country Status (18)

Country	Link
US (1)	US5587495A (fi)
EP (1)	EP0366973B1 (fi)
JP (1)	JPH04501414A (fi)
KR (1)	KR900701812A (fi)
AT (1)	ATE99318T1 (fi)
AU (1)	AU624444B2 (fi)
DE (1)	DE68911855T2 (fi)
DK (1)	DK168597B1 (fi)
ES (1)	ES2061871T3 (fi)
FI (1)	FI93364C (fi)
GB (1)	GB8824947D0 (fi)
HU (1)	HU207733B (fi)
IE (1)	IE64161B1 (fi)
IL (1)	IL92052A (fi)
NZ (1)	NZ231052A (fi)
PT (1)	PT92080B (fi)
WO (1)	WO1990004601A1 (fi)
ZA (1)	ZA898052B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8803301D0 (en) *	1988-02-12	1988-03-09	Erba Carlo Spa	Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) *	1988-04-11	1988-05-11	Erba Carlo Spa	Process for preparing 4-demethoxydauno-mycinone
NL9001834A (nl) *	1990-08-16	1992-03-16	Pharmachemie Bv	Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten.
CN100379749C (zh) *	2003-05-21	2008-04-09	獀洛克斯股份有限公司	4-r-取代的4-去甲氧基柔红霉素的制备方法
US7053191B2 (en) *	2003-05-21	2006-05-30	Solux Corporation	Method of preparing 4-R-substituted 4-demethoxydaunorubicin
US8802830B2 (en) *	2005-12-20	2014-08-12	Solux Corporation	Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) *	2008-01-08	2013-01-22	Solux Corporation	Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en)	2011-04-29	2014-09-30	Synbias Pharma Ag	Method of producing 4-demethoxydaunorubicin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1500421A (en) *	1975-01-22	1978-02-08	Farmaceutici Italia	Optically active anthracyclinones
US4116981A (en) *	1977-05-02	1978-09-26	Yuh-Geng Tsay	5,12-epoxy-naphthacene-6,11-dione derivatives
AU567978B2 (en) *	1983-10-19	1987-12-10	Anti-Cancer Council Of Victoria	Carminomycinone precursors and analogues and derivatives thereof.
EP0159357B1 (en) *	1983-10-19	1992-09-09	The University Of Melbourne	Carminomycinone precursors and analogues and derivatives thereof

1988
- 1988-10-25 GB GB888824947A patent/GB8824947D0/en active Pending
1989
- 1989-10-06 ES ES89118648T patent/ES2061871T3/es not_active Expired - Lifetime
- 1989-10-06 DE DE89118648T patent/DE68911855T2/de not_active Expired - Fee Related
- 1989-10-06 AT AT89118648T patent/ATE99318T1/de not_active IP Right Cessation
- 1989-10-06 EP EP89118648A patent/EP0366973B1/en not_active Expired - Lifetime
- 1989-10-18 NZ NZ231052A patent/NZ231052A/xx unknown
- 1989-10-19 IL IL9205289A patent/IL92052A/en not_active IP Right Cessation
- 1989-10-23 IE IE340789A patent/IE64161B1/en not_active IP Right Cessation
- 1989-10-23 PT PT92080A patent/PT92080B/pt not_active IP Right Cessation
- 1989-10-24 AU AU44962/89A patent/AU624444B2/en not_active Ceased
- 1989-10-24 KR KR1019900701338A patent/KR900701812A/ko active IP Right Grant
- 1989-10-24 ZA ZA898052A patent/ZA898052B/xx unknown
- 1989-10-24 US US07/678,352 patent/US5587495A/en not_active Expired - Fee Related
- 1989-10-24 JP JP1511359A patent/JPH04501414A/ja active Pending
- 1989-10-24 HU HU896397A patent/HU207733B/hu not_active IP Right Cessation
- 1989-10-24 WO PCT/EP1989/001266 patent/WO1990004601A1/en active IP Right Grant
1991
- 1991-04-22 FI FI911952A patent/FI93364C/fi not_active IP Right Cessation
- 1991-04-24 DK DK075291A patent/DK168597B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT92080A (pt)	1990-04-30
HU896397D0 (en)	1991-07-29
IE64161B1 (en)	1995-07-12
IL92052A (en)	1994-06-24
EP0366973A1 (en)	1990-05-09
KR900701812A (ko)	1990-12-04
FI93364B (fi)	1994-12-15
AU624444B2 (en)	1992-06-11
HU207733B (en)	1993-05-28
EP0366973B1 (en)	1993-12-29
NZ231052A (en)	1991-04-26
IE893407L (en)	1990-04-25
FI93364C (fi)	1995-03-27
ZA898052B (en)	1990-08-29
WO1990004601A1 (en)	1990-05-03
PT92080B (pt)	1995-06-30
DK75291A (da)	1991-06-20
GB8824947D0 (en)	1988-11-30
US5587495A (en)	1996-12-24
ATE99318T1 (de)	1994-01-15
JPH04501414A (ja)	1992-03-12
AU4496289A (en)	1990-05-14
DE68911855T2 (de)	1994-04-21
DK75291D0 (da)	1991-04-24
IL92052A0 (en)	1990-07-12
HUT57228A (en)	1991-11-28
DE68911855D1 (de)	1994-02-10
DK168597B1 (da)	1994-05-02
ES2061871T3 (es)	1994-12-16

Legal Events

Date	Code	Title	Description
1994-11-16	BB	Publication of examined application
1997-10-24	MM	Patent lapsed

Publication	Publication Date	Title
PT83843B (pt)	1989-01-17	Processo para a preparacao de promedicamentos de rapamicina
AU7987187A (en)	1988-04-21	Heterocyclic derivatives
RO93855A (ro)	1988-02-29	Procedeu pentru prepararea de arilciclobutilalchilamina
FI93364B (fi)	1994-12-15	Uudet, 4-substituoidut antrasyklinonit ja antrasykliiniglykosidit ja menetelmä niiden valmistamiseksi
DK0488513T3 (da)	1996-06-17	Anvendelse af dioxabicyclo(3.3.0)octanderivater til fremstilling af et medikament til inhibering af cholesterolmetabolismen
EP0339671A3 (en)	1991-05-15	Derivative of caffeic acid and pharmaceutical composition containing the same
FI911016A0 (fi)	1991-02-28	Menetelmä farmakologisesti aktiivisten substituoitujen -diketonien valmistamiseksi
FI91762C (fi)	1994-08-10	4-substituoidut antrasyklinonit ja -antrasykliiniglykosidit ja niiden valmistaminen
DE69029781D1 (de)	1997-03-06	Anthracyclinglycosid-Derivate und Verfahren zu ihrer Herstellung
PT90291A (pt)	1989-11-10	Processo para a preparacao de compostos afins das avermectinas uteis como agentes antiparasiticos
FI844184L (fi)	1985-04-26	Isokinolinderivat och foerfarande foer framstaellning daerav.
ES2026548T3 (es)	1992-05-01	Un procedimiento para preparar penemos.
IL78625A (en)	1990-11-29	3(2h)-furanone 4-(1-alkoxy)methoxy derivatives and their preparation