FI904614A0 - Foerfarande foer framstaellning av nya bensopyranon-beta-d-tioxylosider. - Google Patents

Foerfarande foer framstaellning av nya bensopyranon-beta-d-tioxylosider.

Info

Publication number
FI904614A0
FI904614A0 FI904614A FI904614A FI904614A0 FI 904614 A0 FI904614 A0 FI 904614A0 FI 904614 A FI904614 A FI 904614A FI 904614 A FI904614 A FI 904614A FI 904614 A0 FI904614 A0 FI 904614A0
Authority
FI
Finland
Prior art keywords
group
beta
atom
thioxylosider
bensopyranon
Prior art date
Application number
FI904614A
Other languages
English (en)
Other versions
FI100183B (fi
Inventor
Soth Samreth
Veronique Barberousse
Patrice Renaut
Francois Bellamy
Jean Millet
Original Assignee
Fournier Innovation Synergie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8912452A external-priority patent/FR2652353B1/fr
Priority claimed from FR9003401A external-priority patent/FR2659659B1/fr
Application filed by Fournier Innovation Synergie filed Critical Fournier Innovation Synergie
Publication of FI904614A0 publication Critical patent/FI904614A0/fi
Application granted granted Critical
Publication of FI100183B publication Critical patent/FI100183B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
FI904614A 1989-09-22 1990-09-19 Menetelmä ja välituotteita uusien, terapeuttisesti käyttökelpoisten be ntsopyranoni- -D-tioksylosidien valmistamiseksi FI100183B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8912452 1989-09-22
FR8912452A FR2652353B1 (fr) 1989-09-22 1989-09-22 Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR9003401A FR2659659B1 (fr) 1990-03-16 1990-03-16 Nouveaux benzopyran-4-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR9003401 1990-03-16

Publications (2)

Publication Number Publication Date
FI904614A0 true FI904614A0 (fi) 1990-09-19
FI100183B FI100183B (fi) 1997-10-15

Family

ID=26227568

Family Applications (1)

Application Number Title Priority Date Filing Date
FI904614A FI100183B (fi) 1989-09-22 1990-09-19 Menetelmä ja välituotteita uusien, terapeuttisesti käyttökelpoisten be ntsopyranoni- -D-tioksylosidien valmistamiseksi

Country Status (24)

Country Link
US (1) US5169838A (fi)
EP (1) EP0421829B1 (fi)
JP (1) JPH07103147B2 (fi)
KR (1) KR0142670B1 (fi)
CN (1) CN1027268C (fi)
AT (1) ATE113956T1 (fi)
AU (2) AU631456B2 (fi)
CA (1) CA2024476C (fi)
DE (1) DE69014064T2 (fi)
DK (1) DK0421829T3 (fi)
ES (1) ES2066165T3 (fi)
FI (1) FI100183B (fi)
GR (1) GR3014966T3 (fi)
HR (1) HRP920811B1 (fi)
HU (1) HU207867B (fi)
IE (1) IE65092B1 (fi)
IL (1) IL95582A (fi)
NO (1) NO172987C (fi)
NZ (1) NZ245783A (fi)
PT (1) PT95369B (fi)
RU (1) RU1838323C (fi)
SK (1) SK280827B6 (fi)
UA (1) UA13476A (fi)
YU (1) YU47867B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801055B1 (fr) 1999-11-17 2002-02-08 Fournier Ind & Sante Derives de beta-d-5-thioxylose, procede de preparation et utilisation en therapeutique
FR2824559B1 (fr) 2001-05-11 2004-02-13 Fournier Lab Sa Nouveaux derives 5-thio-beta-xylopyronasides, procede de preparation, compositions pharmaceutiques les contenant et leur utilisation en therapeutique
FR2846966A1 (fr) * 2002-11-07 2004-05-14 Fournier Lab Sa Derive du 4-methyl-2-oxo-2h-1-benzopyran-7-yl 5-thio-beta-d- xylopyranoside, son procede de preparation et composition pharmaceutique le contenant
US7439260B2 (en) * 2003-06-11 2008-10-21 Merck Forsst Canada & Co. 7-(1,3-thiazol-2-YL)thio-coumarin derivatives and their use as leukotriene biosynthesis inhibitors
FR2860234B1 (fr) 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
AR054226A1 (es) * 2005-02-18 2007-06-13 Smithkline Beecham Corp Composicion farmaceutica en forma de comprimido que comprende el compuesto 4-metil-2oxo-2h-1-benzopiran-7-il-tio-b-d-xilopiranosido, uso de sulfato de dermatan y de dicho compuesto para prepararla y metodo para su preparacion
FR2903698B1 (fr) 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906247B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
US20090075914A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched odiparcil
CN101397315B (zh) * 2007-09-24 2013-08-07 中国医学科学院药物研究所 香豆素苷类化合物、其制法和其药物组合物与用途
FR3011468B1 (fr) * 2013-10-04 2015-12-04 Inventiva Utilisation de l'odiparcil dans le traitement d'une mucopolysaccharidose
US10092540B2 (en) 2013-10-04 2018-10-09 Inventiva Method of treatment of a mucopolysaccharidosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034306A1 (de) * 1970-07-10 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof 2 (3,4 Dimethyl-cumarin 7 yl) oxy alkylcarbonsaure Derivate und Verfahren zu ihrer Herstellung
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique
JPS6013788A (ja) * 1983-07-05 1985-01-24 Yamanouchi Pharmaceut Co Ltd 新規なクマリン誘導体
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
US4681954A (en) * 1985-10-07 1987-07-21 Pennwalt Corporation 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
DK0421829T3 (da) 1995-01-16
YU178790A (sh) 1992-12-21
JPH07103147B2 (ja) 1995-11-08
NO172987C (no) 1993-10-06
NO904088D0 (no) 1990-09-19
AU6253190A (en) 1991-03-28
PT95369A (pt) 1991-05-22
HU906005D0 (en) 1991-03-28
DE69014064D1 (de) 1994-12-15
HU207867B (en) 1993-06-28
HUT55794A (en) 1991-06-28
DE69014064T2 (de) 1995-05-18
UA13476A (uk) 1997-04-25
HRP920811A2 (en) 1995-10-31
CN1050544A (zh) 1991-04-10
NO904088L (no) 1991-03-25
CN1027268C (zh) 1995-01-04
IE903414A1 (en) 1991-04-10
ES2066165T3 (es) 1995-03-01
IE65092B1 (en) 1995-10-04
HRP920811B1 (en) 1998-12-31
SK463890A3 (en) 2000-08-14
FI100183B (fi) 1997-10-15
YU47867B (sh) 1996-02-19
ATE113956T1 (de) 1994-11-15
NZ245783A (en) 1993-07-27
SK280827B6 (sk) 2000-08-14
RU1838323C (ru) 1993-08-30
EP0421829A1 (fr) 1991-04-10
CA2024476C (en) 1999-10-12
AU642829B2 (en) 1993-10-28
JPH03120292A (ja) 1991-05-22
EP0421829B1 (fr) 1994-11-09
GR3014966T3 (en) 1995-05-31
IL95582A (en) 2001-06-14
AU2539792A (en) 1992-11-26
IL95582A0 (en) 1991-06-30
KR0142670B1 (ko) 1998-07-01
US5169838A (en) 1992-12-08
NO172987B (no) 1993-06-28
AU631456B2 (en) 1992-11-26
CA2024476A1 (en) 1991-03-23
KR910006283A (ko) 1991-04-29
PT95369B (pt) 1997-06-30

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Legal Events

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FG Patent granted

Owner name: FOURNIER INDUSTRIE ET SANTE

MA Patent expired