FI750652A - - Google Patents

Info

Publication number
FI750652A
FI750652A FI750652A FI750652A FI750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A
Authority
FI
Finland
Application number
FI750652A
Other languages
Finnish (fi)
Other versions
FI63571B (fi
FI63571C (fi
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI750652A publication Critical patent/FI750652A/fi
Publication of FI63571B publication Critical patent/FI63571B/fi
Application granted granted Critical
Publication of FI63571C publication Critical patent/FI63571C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI750652A 1974-03-09 1975-03-06 Foerfarande foer framstaellning av analgetiskt verkande racemiska eller diastereomera och optiskt aktiva 2-tetrahydrofurfuryl-(1r/s 5r/s 9r/s)-2'-hydroxi-5,9-dimetyl-6,7-bensomorfaner och deras syraadditionssalter FI63571C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2411382 1974-03-09
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (3)

Publication Number Publication Date
FI750652A true FI750652A (fr) 1975-09-10
FI63571B FI63571B (fi) 1983-03-31
FI63571C FI63571C (fi) 1983-07-11

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750652A FI63571C (fi) 1974-03-09 1975-03-06 Foerfarande foer framstaellning av analgetiskt verkande racemiska eller diastereomera och optiskt aktiva 2-tetrahydrofurfuryl-(1r/s 5r/s 9r/s)-2'-hydroxi-5,9-dimetyl-6,7-bensomorfaner och deras syraadditionssalter

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fr)
AT (1) AT344332B (fr)
BE (1) BE826440A (fr)
BG (3) BG25087A3 (fr)
CA (1) CA1049511A (fr)
CH (8) CH612425A5 (fr)
CS (1) CS188221B2 (fr)
DD (1) DD119236A5 (fr)
DE (1) DE2411382C3 (fr)
DK (1) DK137188C (fr)
ES (6) ES440346A1 (fr)
FI (1) FI63571C (fr)
FR (1) FR2262984B1 (fr)
GB (1) GB1496418A (fr)
HU (1) HU177408B (fr)
IE (1) IE40945B1 (fr)
IL (1) IL46760A (fr)
NL (1) NL7502724A (fr)
NO (1) NO141800C (fr)
PH (1) PH14127A (fr)
PL (3) PL93700B1 (fr)
RO (2) RO69617A (fr)
SE (1) SE421919B (fr)
SU (3) SU577982A3 (fr)
ZA (1) ZA751394B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
PT820432E (pt) * 1995-03-10 2001-09-28 Photocure Asa Esteres do acido 5-aminolevulinico como agentes fotossensibilizadores em fotoquimioterapia
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (fr) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques d'urée de la 11béta-hydroxystéroïde déhydrogénase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
WO2009102460A2 (fr) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibiteurs de 11beta-hydroxystéroïde deshydrogénase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
EP2291370B1 (fr) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déhydrogénase 1
WO2009134400A1 (fr) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déhydrogénase 1
EP2288596B1 (fr) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Dérivés d acide carboxylique alicyclique de benzomorphanes et échafaudages afférents, médicaments contenant ces composés, et utilisation de ceux-ci
CA2729998A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs de la 11 beta-hydroxysteroide deshydrogenase 1
CA2730499A1 (fr) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibiteurs cycliques de la 11 beta-hydroxysteroide deshydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (fr) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Inhibiteurs cycliques de la 11-bêta-hydroxystéroïde déshydrogénase 1 basée sur la structure 1,3-oxazinan-2-one
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
CH620439A5 (en) 1980-11-28
FI63571B (fi) 1983-03-31
JPS5827275B2 (ja) 1983-06-08
BG24814A4 (en) 1978-05-12
FR2262984B1 (fr) 1978-07-28
ES440345A1 (es) 1977-03-01
NO141800B (no) 1980-02-04
CH622014A5 (en) 1981-03-13
PL93700B1 (fr) 1977-06-30
NO750773L (fr) 1975-09-10
CH622015A5 (en) 1981-03-13
SE7502592L (fr) 1975-09-10
ES440350A1 (es) 1977-03-16
NO141800C (no) 1980-06-04
PL93499B1 (fr) 1977-05-30
DE2411382C3 (de) 1979-09-06
PH14127A (en) 1981-02-26
IL46760A (en) 1978-12-17
CH620440A5 (en) 1980-11-28
CS188221B2 (en) 1979-02-28
BG25087A3 (en) 1978-07-12
BE826440A (fr) 1975-09-08
ZA751394B (en) 1976-11-24
RO69617A (fr) 1980-08-15
JPS50123675A (fr) 1975-09-29
DK137188B (da) 1978-01-30
ES440348A1 (es) 1977-06-01
CH620681A5 (en) 1980-12-15
CH612425A5 (en) 1979-07-31
IL46760A0 (en) 1975-05-22
DE2411382B2 (de) 1979-01-18
HU177408B (en) 1981-10-28
SU577983A3 (ru) 1977-10-25
ES440346A1 (es) 1977-03-01
AU7894275A (en) 1976-09-16
FI63571C (fi) 1983-07-11
CH622016A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
SE421919B (sv) 1982-02-08
DE2411382A1 (de) 1975-09-18
NL7502724A (nl) 1975-09-11
DK137188C (da) 1978-07-03
IE40945B1 (en) 1979-09-12
SU588916A3 (ru) 1978-01-15
AT344332B (de) 1978-07-10
FR2262984A1 (fr) 1975-10-03
ES440347A1 (es) 1977-06-01
GB1496418A (en) 1977-12-30
DK92975A (fr) 1975-09-10
CA1049511A (fr) 1979-02-27
DD119236A5 (fr) 1976-04-12
IE40945L (en) 1975-09-09
PL93699B1 (fr) 1977-06-30
RO70051A (fr) 1980-12-30
SU577982A3 (ru) 1977-10-25
ES440349A1 (es) 1977-03-01
BG24813A4 (en) 1978-05-12
ATA153875A (de) 1977-11-15

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: C.H. BOEHRINGER SOHN