CH612425A5 - Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans - Google Patents

Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans

Info

Publication number: CH612425A5
Authority: CH; Switzerland
Prior art keywords: benzomorphans; tetrahydrofurfuryl; novel; preparation
Prior art date: 1974-03-09

Application number

CH280275A

Inventor

Herbert Dr Merz

Adolf Dr Langbein

Gerhard Dr Walther

Klaus Dr Stockhaus

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-03-09

Filing date

1975-03-05

Publication date

1979-07-31

1975-03-05 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1979-07-31 Publication of CH612425A5 publication Critical patent/CH612425A5/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CH280275A 1974-03-09 1975-03-05 Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans CH612425A5 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2411382A DE2411382C3 (en)	1974-03-09	1974-03-09	2-Tetrahydrofurfuryl-6,7-benzomorphane, process for the preparation and their use

Publications (1)

Publication Number	Publication Date
CH612425A5 true CH612425A5 (en)	1979-07-31

Family

ID=5909593

Family Applications (8)

Application Number	Title	Priority Date	Filing Date
CH280275A CH612425A5 (en)	1974-03-09	1975-03-05	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384579A CH622015A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384979A CH622017A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384479A CH622014A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384879A CH620681A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384679A CH620440A5 (en)	1974-03-09	1979-04-24	Process for the preparation of 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384379A CH620439A5 (en)	1974-03-09	1979-04-24	Process for the preparation of 2-tetrahydrofurfuryl- 6,7-benzomorphans
CH384779A CH622016A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans

Family Applications After (7)

Application Number	Title	Priority Date	Filing Date
CH384579A CH622015A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384979A CH622017A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384479A CH622014A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384879A CH620681A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384679A CH620440A5 (en)	1974-03-09	1979-04-24	Process for the preparation of 2-tetrahydrofurfuryl-6,7-benzomorphans
CH384379A CH620439A5 (en)	1974-03-09	1979-04-24	Process for the preparation of 2-tetrahydrofurfuryl- 6,7-benzomorphans
CH384779A CH622016A5 (en)	1974-03-09	1979-04-24	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans

Country Status (25)

Country	Link
JP (1)	JPS5827275B2 (en)
AT (1)	AT344332B (en)
BE (1)	BE826440A (en)
BG (3)	BG25087A3 (en)
CA (1)	CA1049511A (en)
CH (8)	CH612425A5 (en)
CS (1)	CS188221B2 (en)
DD (1)	DD119236A5 (en)
DE (1)	DE2411382C3 (en)
DK (1)	DK137188C (en)
ES (6)	ES440346A1 (en)
FI (1)	FI63571C (en)
FR (1)	FR2262984B1 (en)
GB (1)	GB1496418A (en)
HU (1)	HU177408B (en)
IE (1)	IE40945B1 (en)
IL (1)	IL46760A (en)
NL (1)	NL7502724A (en)
NO (1)	NO141800C (en)
PH (1)	PH14127A (en)
PL (3)	PL93699B1 (en)
RO (2)	RO69617A (en)
SE (1)	SE421919B (en)
SU (3)	SU577982A3 (en)
ZA (1)	ZA751394B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2716687A1 (en) *	1977-04-15	1978-10-19	Boehringer Sohn Ingelheim	2'-HYDROXY-2- (5-ISOXAZOLYLMETHYL) -6.7BENZOMORPHANES, THEIR ACID ADDITIONAL SALTS AND MEDICINAL PRODUCTS CONTAINING THEM
DE2828039A1 (en) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2- (2-ALKOXYETHYL) -2'-HYDROXY-6,7-BENZOMORPHANES THEIR ACID ADDITION SALTS, THESE MEDICINAL PRODUCTS, AND METHOD FOR THE PRODUCTION THEREOF
US6492420B2 (en)	1995-03-10	2002-12-10	Photocure As	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en)	1995-03-10	2009-05-12	Photocure Asa	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en)	1995-03-10	2006-01-31	Photocure Asa	Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
HU225148B1 (en) *	1995-03-10	2006-07-28	Photocure Asa	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy or diagnosis, products and kits comprising thereof and method of in vitro diagnosis by their using
GB0018528D0 (en)	2000-07-27	2000-09-13	Photocure Asa	Compounds
US6723750B2 (en)	2002-03-15	2004-04-20	Allergan, Inc.	Photodynamic therapy for pre-melanomas
EP2183228B1 (en)	2007-07-26	2014-08-20	Vitae Pharmaceuticals, Inc.	CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1
WO2009063061A2 (en)	2007-11-16	2009-05-22	Boehringer Ingelheim International Gmbh	Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en)	2007-12-11	2009-06-18	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en)	2008-01-24	2009-07-30	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en)	2008-02-15	2010-12-01	Vitae Pharmaceuticals, Inc.	Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (en)	2008-05-01	2013-11-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2722427A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en)	2008-05-13	2009-12-16	Boehringer Ingelheim Int	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
AU2009274567B2 (en)	2008-07-25	2013-04-04	Boehringer Ingelheim International Gmbh	Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
WO2010010157A2 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
US8680093B2 (en)	2009-04-30	2014-03-25	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en)	2009-06-11	2011-01-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (en)	2009-11-06	2011-12-07	Boehringer Ingelheim Int	ARILO AND HETEROARILCARBONILO DERIVATIVES OF HEXAHYDROINDENOPIRIDINE AND OCTAHYDROBENZOQUINOLINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (en)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
US8735585B2 (en)	2011-08-17	2014-05-27	Boehringer Ingelheim International Gmbh	Indenopyridine derivatives

1974
- 1974-03-09 DE DE2411382A patent/DE2411382C3/en not_active Expired
1975
- 1975-02-28 AT AT153875A patent/AT344332B/en not_active IP Right Cessation
- 1975-03-05 CH CH280275A patent/CH612425A5/en not_active IP Right Cessation
- 1975-03-05 SU SU7502110984A patent/SU577982A3/en active
- 1975-03-06 FI FI750652A patent/FI63571C/en not_active IP Right Cessation
- 1975-03-07 ZA ZA751394A patent/ZA751394B/en unknown
- 1975-03-07 BG BG7500029183A patent/BG25087A3/en unknown
- 1975-03-07 RO RO7589653A patent/RO69617A/en unknown
- 1975-03-07 IL IL46760A patent/IL46760A/en unknown
- 1975-03-07 BG BG7500030537A patent/BG24813A4/en unknown
- 1975-03-07 NL NL7502724A patent/NL7502724A/en not_active Application Discontinuation
- 1975-03-07 FR FR7507239A patent/FR2262984B1/fr not_active Expired
- 1975-03-07 BG BG7500030538A patent/BG24814A4/en unknown
- 1975-03-07 DK DK92975A patent/DK137188C/en active
- 1975-03-07 BE BE154138A patent/BE826440A/en not_active IP Right Cessation
- 1975-03-07 IE IE505/75A patent/IE40945B1/en unknown
- 1975-03-07 GB GB9633/75A patent/GB1496418A/en not_active Expired
- 1975-03-07 NO NO750773A patent/NO141800C/en unknown
- 1975-03-07 CA CA221,554A patent/CA1049511A/en not_active Expired
- 1975-03-07 DD DD184642A patent/DD119236A5/xx unknown
- 1975-03-07 JP JP50027915A patent/JPS5827275B2/en not_active Expired
- 1975-03-07 SE SE7502592A patent/SE421919B/en not_active IP Right Cessation
- 1975-03-07 HU HU75BO1536A patent/HU177408B/en unknown
- 1975-03-07 RO RO7589654A patent/RO70051A/en unknown
- 1975-03-08 PL PL1975191318A patent/PL93699B1/pl unknown
- 1975-03-08 PL PL1975191319A patent/PL93700B1/pl unknown
- 1975-03-08 PL PL1975178582A patent/PL93499B1/pl unknown
- 1975-03-10 PH PH16895A patent/PH14127A/en unknown
- 1975-03-10 CS CS751583A patent/CS188221B2/en unknown
- 1975-08-20 ES ES440346A patent/ES440346A1/en not_active Expired
- 1975-08-20 ES ES440348A patent/ES440348A1/en not_active Expired
- 1975-08-20 ES ES440350A patent/ES440350A1/en not_active Expired
- 1975-08-20 ES ES440349A patent/ES440349A1/en not_active Expired
- 1975-08-20 ES ES440345A patent/ES440345A1/en not_active Expired
- 1975-08-20 ES ES440347A patent/ES440347A1/en not_active Expired
- 1975-12-19 SU SU7502199294A patent/SU577983A3/en active
- 1975-12-19 SU SU752199295A patent/SU588916A3/en active
1979
- 1979-04-24 CH CH384579A patent/CH622015A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384979A patent/CH622017A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384479A patent/CH622014A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384879A patent/CH620681A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384679A patent/CH620440A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384379A patent/CH620439A5/en not_active IP Right Cessation
- 1979-04-24 CH CH384779A patent/CH622016A5/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES440349A1 (en)	1977-03-01
DE2411382B2 (en)	1979-01-18
NO141800B (en)	1980-02-04
PL93499B1 (en)	1977-05-30
CH620439A5 (en)	1980-11-28
CH622014A5 (en)	1981-03-13
HU177408B (en)	1981-10-28
SU577983A3 (en)	1977-10-25
BE826440A (en)	1975-09-08
PH14127A (en)	1981-02-26
IE40945L (en)	1975-09-09
CH620681A5 (en)	1980-12-15
ES440347A1 (en)	1977-06-01
SE7502592L (en)	1975-09-10
DD119236A5 (en)	1976-04-12
CH622017A5 (en)	1981-03-13
SU588916A3 (en)	1978-01-15
SE421919B (en)	1982-02-08
ES440348A1 (en)	1977-06-01
BG24814A4 (en)	1978-05-12
ES440350A1 (en)	1977-03-16
BG24813A4 (en)	1978-05-12
DK92975A (en)	1975-09-10
IL46760A (en)	1978-12-17
GB1496418A (en)	1977-12-30
CS188221B2 (en)	1979-02-28
RO70051A (en)	1980-12-30
IE40945B1 (en)	1979-09-12
FR2262984B1 (en)	1978-07-28
JPS50123675A (en)	1975-09-29
CH622016A5 (en)	1981-03-13
ES440345A1 (en)	1977-03-01
DE2411382A1 (en)	1975-09-18
CA1049511A (en)	1979-02-27
BG25087A3 (en)	1978-07-12
FR2262984A1 (en)	1975-10-03
RO69617A (en)	1980-08-15
JPS5827275B2 (en)	1983-06-08
ZA751394B (en)	1976-11-24
FI63571B (en)	1983-03-31
PL93700B1 (en)	1977-06-30
FI63571C (en)	1983-07-11
CH622015A5 (en)	1981-03-13
ATA153875A (en)	1977-11-15
NO750773L (en)	1975-09-10
AT344332B (en)	1978-07-10
DK137188C (en)	1978-07-03
ES440346A1 (en)	1977-03-01
SU577982A3 (en)	1977-10-25
FI750652A (en)	1975-09-10
PL93699B1 (en)	1977-06-30
DK137188B (en)	1978-01-30
AU7894275A (en)	1976-09-16
NO141800C (en)	1980-06-04
DE2411382C3 (en)	1979-09-06
IL46760A0 (en)	1975-05-22
CH620440A5 (en)	1980-11-28
NL7502724A (en)	1975-09-11

Legal Events

Date	Code	Title	Description
1989-11-30	PL	Patent ceased

Publication	Publication Date	Title
CH612425A5 (en)	1979-07-31	Process for the preparation of novel 2-tetrahydrofurfuryl-6,7-benzomorphans
GB1536407A (en)	1978-12-20	Process for the preparation of bis-indolic compounds
EG12104A (en)	1978-06-30	Process for preparing of 1,1-diaryl-1-oxadiazol-alkylamines
ZA755889B (en)	1976-08-25	Process for the preparation of new catalysts
CH613193A5 (en)	1979-09-14	Process for the preparation of novel 2-arylamino-2-imidazoline derivatives
CH613683A5 (en)	1979-10-15	Process for the preparation of secoprostaglandins
IL48062A0 (en)	1975-11-25	Process for the preparation of metasubstituted halogenophenols
CH614194A5 (en)	1979-11-15	Process for the preparation of 5-aroyl- and 5-thenoyl-pyrrole compounds
EG13030A (en)	1980-10-31	Process for the production of n,n diallyldichloroacetamide
IE42100L (en)	1976-06-30	Process for the preparation of 2, 2, 2-trichloroethyl¹chloroformate
CH614935A5 (en)	1979-12-28	Process for the preparation of novel 9-thia-, 9-oxothia- and 9-dioxothia-11,12-secoprostaglandins
YU39940B (en)	1985-06-30	Process for dehydrohalogenization of 7-halo-or 1,7-dihalo -dihydrocedeinone dialkylketals
GB1519826A (en)	1978-08-02	Process for the preparation of 11 - hydroxy - 18 - alkylestrane compounds
CH611273A5 (en)	1979-05-31	Process for the preparation of novel 3-oxocyclohex-1-en-1-yl- ureas
ZA75976B (en)	1976-01-28	Process for the preparation of cis-vincamine
CH612932A5 (en)	1979-08-31	Process for the preparation of alkylsulphonylphenoxy-propanolamines
IL47849A (en)	1979-05-31	Process for the preparation of poly-(-n-alkyliminoalanes)
CH614199A5 (en)	1979-11-15	Process for the preparation of 2-halomethyl-1,4-benzodiazepines
EG12396A (en)	1978-12-31	Process for preparing of 3,7-dimethyl-3-hydroxy-6-octenenitrile
ZA753469B (en)	1976-05-26	Process for the preparation of alpha-diol-alpha-dioxo compounds
CH613206A5 (en)	1979-09-14	Process for the preparation of 1-aminomethyl-6-phenyltriazolobenzodiazepine compounds
AU7803675A (en)	1976-08-12	Process for the preparation of polymerisable, stable, organicdispersions
CH614712A5 (en)	1979-12-14	Process for the preparation of the novel alpha-amino-2-adamantylmethylpenicillin
CH613696A5 (en)	1979-10-15	Process for the preparation of novel 5-amino-7-phenyl-2,3-dihydro-1H-1,4-diazepines
IL48633A0 (en)	1976-02-29	Process for the preparation of trichlorothiazole