CS188221B2 - Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes - Google Patents

Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes

Info

Publication number
CS188221B2
CS188221B2 CS751583A CS158375A CS188221B2 CS 188221 B2 CS188221 B2 CS 188221B2 CS 751583 A CS751583 A CS 751583A CS 158375 A CS158375 A CS 158375A CS 188221 B2 CS188221 B2 CS 188221B2
Authority
CS
Czechoslovakia
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
producing new
producing
new
Prior art date
Application number
CS751583A
Other languages
Czech (cs)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CS775011A priority Critical patent/CS188250B2/en
Priority to CS775010A priority patent/CS188249B2/en
Publication of CS188221B2 publication Critical patent/CS188221B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CS751583A 1974-03-09 1975-03-10 Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes CS188221B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS775011A CS188250B2 (en) 1974-03-09 1977-07-28 Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes
CS775010A CS188249B2 (en) 1974-03-09 1977-07-28 Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (en) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, process for the preparation and their use

Publications (1)

Publication Number Publication Date
CS188221B2 true CS188221B2 (en) 1979-02-28

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
CS751583A CS188221B2 (en) 1974-03-09 1975-03-10 Method of producing new 2-tetrahydrofurfuryl-6,7-benzomorphanes

Country Status (25)

Country Link
JP (1) JPS5827275B2 (en)
AT (1) AT344332B (en)
BE (1) BE826440A (en)
BG (3) BG24814A4 (en)
CA (1) CA1049511A (en)
CH (8) CH612425A5 (en)
CS (1) CS188221B2 (en)
DD (1) DD119236A5 (en)
DE (1) DE2411382C3 (en)
DK (1) DK137188C (en)
ES (6) ES440345A1 (en)
FI (1) FI63571C (en)
FR (1) FR2262984B1 (en)
GB (1) GB1496418A (en)
HU (1) HU177408B (en)
IE (1) IE40945B1 (en)
IL (1) IL46760A (en)
NL (1) NL7502724A (en)
NO (1) NO141800C (en)
PH (1) PH14127A (en)
PL (3) PL93699B1 (en)
RO (2) RO70051A (en)
SE (1) SE421919B (en)
SU (3) SU577982A3 (en)
ZA (1) ZA751394B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (en) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-HYDROXY-2- (5-ISOXAZOLYLMETHYL) -6.7BENZOMORPHANES, THEIR ACID ADDITIONAL SALTS AND MEDICINAL PRODUCTS CONTAINING THEM
DE2828039A1 (en) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2- (2-ALKOXYETHYL) -2'-HYDROXY-6,7-BENZOMORPHANES THEIR ACID ADDITION SALTS, THESE MEDICINAL PRODUCTS, AND METHOD FOR THE PRODUCTION THEREOF
JP3955093B2 (en) * 1995-03-10 2007-08-08 フォトキュア エイエスエイ Esters of 5-aminolevulinic acid as photosensitizers in photochemical therapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ATE554078T1 (en) 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc SYNTHESIS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 INHIBITORS
CL2008003407A1 (en) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Substituted heterobicyclo aryl- and heteroarylcarbonyl derivative compounds; pharmaceutical composition; preparation procedure; and its use in the treatment and / or prevention of metabolic disorders, mediated by the inhibition of the enzyme hsd-1.
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5730021B2 (en) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド Cycloalkyllactam derivatives as inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071236A1 (en) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc CYCLE INHIBITORS OF 11BETA-HYDROXIESTEROID DEHYDROGENASE 1
AR071609A1 (en) 2008-05-01 2010-06-30 Vitae Pharmaceuticals Inc CYCLICAL INHIBITORS OF 11 (BETA) -HYDROXIESTEROID DEHYDROGENASE 1
CL2009001151A1 (en) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compounds derived from benzomorphane alicyclic carbocyclic acids, preparation procedure, pharmaceutical composition, useful for treating diseases influenced by the inhibition of the enzyme 11beta-hydroxysteroid dehydrogenase, such as metabolic disorders.
WO2010010157A2 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CA2730499A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (en) 2009-04-30 2012-04-02 Boehringer Ingelheim Int CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (en) 2009-11-06 2016-05-01 維它藥物公司 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (en) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IE40945L (en) 1975-09-09
ES440346A1 (en) 1977-03-01
IE40945B1 (en) 1979-09-12
RO69617A (en) 1980-08-15
FI63571B (en) 1983-03-31
ES440348A1 (en) 1977-06-01
CH622016A5 (en) 1981-03-13
CH622015A5 (en) 1981-03-13
DD119236A5 (en) 1976-04-12
AU7894275A (en) 1976-09-16
SU588916A3 (en) 1978-01-15
IL46760A (en) 1978-12-17
ES440350A1 (en) 1977-03-16
BG24813A4 (en) 1978-05-12
NO750773L (en) 1975-09-10
HU177408B (en) 1981-10-28
DK92975A (en) 1975-09-10
DK137188B (en) 1978-01-30
CA1049511A (en) 1979-02-27
PL93699B1 (en) 1977-06-30
CH622014A5 (en) 1981-03-13
FR2262984A1 (en) 1975-10-03
SU577983A3 (en) 1977-10-25
IL46760A0 (en) 1975-05-22
CH612425A5 (en) 1979-07-31
PL93499B1 (en) 1977-05-30
BG25087A3 (en) 1978-07-12
RO70051A (en) 1980-12-30
DE2411382B2 (en) 1979-01-18
ES440347A1 (en) 1977-06-01
DK137188C (en) 1978-07-03
NO141800C (en) 1980-06-04
BG24814A4 (en) 1978-05-12
CH620681A5 (en) 1980-12-15
JPS5827275B2 (en) 1983-06-08
AT344332B (en) 1978-07-10
CH620440A5 (en) 1980-11-28
NO141800B (en) 1980-02-04
FI63571C (en) 1983-07-11
DE2411382C3 (en) 1979-09-06
ATA153875A (en) 1977-11-15
CH622017A5 (en) 1981-03-13
ZA751394B (en) 1976-11-24
BE826440A (en) 1975-09-08
FR2262984B1 (en) 1978-07-28
NL7502724A (en) 1975-09-11
PL93700B1 (en) 1977-06-30
SE7502592L (en) 1975-09-10
ES440349A1 (en) 1977-03-01
SU577982A3 (en) 1977-10-25
FI750652A (en) 1975-09-10
JPS50123675A (en) 1975-09-29
PH14127A (en) 1981-02-26
CH620439A5 (en) 1980-11-28
ES440345A1 (en) 1977-03-01
GB1496418A (en) 1977-12-30
SE421919B (en) 1982-02-08
DE2411382A1 (en) 1975-09-18

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