ES8602653A1 - Un procedimiento para la separacion de serotonina - Google Patents
Un procedimiento para la separacion de serotoninaInfo
- Publication number
- ES8602653A1 ES8602653A1 ES533890A ES533890A ES8602653A1 ES 8602653 A1 ES8602653 A1 ES 8602653A1 ES 533890 A ES533890 A ES 533890A ES 533890 A ES533890 A ES 533890A ES 8602653 A1 ES8602653 A1 ES 8602653A1
- Authority
- ES
- Spain
- Prior art keywords
- wax
- prepn
- water
- soln
- coffee
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- External Artificial Organs (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA SEPARACION DE LA SEROTONINA DE CERA DEL CAFE, EN PARTICULAR PARA LA PREPARACION DE CIERTOS DERIVADOS DE LA SEROTONINA, DE FORMULA GENERAL (I). CONSISTE EN SOMETER UNA SOLUCION DE CERA DE CAFE A HIDROLISIS ALCALINA, UTILIZANDO UNA BASE FUERTE Y EN PRESENCIA DE AGUA EN UNA ATMOSFERA INERTE. A CONTINUACION SE RECUPERA EL MEDIO REACCIONAL QUE CONTIENE LA SEROTONINA. EL DISOLVENTE PARA LA CERA DEL CAFE ES UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R ES HIDROGENO O UN GRUPO ALQUILO QUE CONTIENE 1 A 4 ATOMOS DE CARBONO; X ES 0 O 1; Y N ES UN NUMERO ENTERO DE 2 A 4, CON LA SALVEDAD DE QUE X NO PUEDE TENER EL VALOR 1 CUANDO N ES 3 O 4.DE APLICACION EN EL TRATAMIENTO DE LA PSICOSIS, MIGRAÑA Y PARA EL CONTROL DE FUMAR EN EXCESO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/510,167 US4506080A (en) | 1983-07-01 | 1983-07-01 | Preparation of serotonine and derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES533890A0 ES533890A0 (es) | 1985-12-16 |
ES8602653A1 true ES8602653A1 (es) | 1985-12-16 |
Family
ID=24029637
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES533890A Expired ES8602653A1 (es) | 1983-07-01 | 1984-06-30 | Un procedimiento para la separacion de serotonina |
ES545230A Granted ES545230A0 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de n-acetil serotonina |
ES545232A Expired ES8603411A1 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de mexamina |
ES545231A Expired ES8604142A1 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de melatonina |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES545230A Granted ES545230A0 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de n-acetil serotonina |
ES545232A Expired ES8603411A1 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de mexamina |
ES545231A Expired ES8604142A1 (es) | 1983-07-01 | 1985-07-16 | Un procedimiento para la preparacion de melatonina |
Country Status (10)
Country | Link |
---|---|
US (1) | US4506080A (es) |
EP (3) | EP0197389B1 (es) |
JP (4) | JPS6025966A (es) |
AT (2) | ATE38513T1 (es) |
DE (1) | DE3462794D1 (es) |
ES (4) | ES8602653A1 (es) |
GB (3) | GB2142622B (es) |
IL (1) | IL71737A (es) |
OA (1) | OA07734A (es) |
ZM (1) | ZM3384A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5877176A (en) * | 1991-12-26 | 1999-03-02 | Cornell Research Foundation, Inc. | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis |
US6080773A (en) | 1997-10-14 | 2000-06-27 | Akzo Nobel, N.V. | Benzylamine derivatives which are useful in treating psychiatric disorders |
IL155666A (en) * | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Insomnia treatment |
US9119846B2 (en) | 2003-04-29 | 2015-09-01 | Neurim Pharmaceuticals (1991) Ltd. | Method and composition for enhancing cognition in alzheimer's patients |
CN104496882A (zh) * | 2014-11-29 | 2015-04-08 | 湖北金赛药业有限公司 | 一种褪黑素的合成方法 |
US20210238124A1 (en) * | 2018-04-20 | 2021-08-05 | The General Hospital Corporation | Acetylated prodrugs for delivery across the blood-brain barrier |
CN110105261A (zh) * | 2018-12-24 | 2019-08-09 | 武汉工程大学 | 一种利用微反应器连续、快速合成及提纯褪黑素的方法 |
ES1237024Y (es) | 2019-09-20 | 2020-01-30 | Normagrup Tech S A | Dispositivo de iluminacion autonomo para la regulacion de ciclos circadianos |
CN113402437B (zh) * | 2021-06-29 | 2023-07-14 | 河北维达康生物科技有限公司 | 一种合成膳食补充剂褪黑素的新方法 |
CN113788780B (zh) * | 2021-10-15 | 2023-06-16 | 河北维达康生物科技有限公司 | 一种n-乙酰基-5-甲氧基色胺的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2156944C3 (de) * | 1971-11-16 | 1974-10-17 | Hag Ag, 2800 Bremen | Verfahren zur Gewinnung von Serotonin aus Kaffeewachs |
CH568719A5 (en) * | 1973-08-22 | 1975-11-14 | Haco Ag | Extracting carboxylic acid 5-hydroxy-tryptamide irritants - from coffee without caffeine extn. by using caffeine - enriched solvents |
DE2435365A1 (de) * | 1973-12-31 | 1976-01-29 | Luigi Di Bella | Pharmazeutisches mittel fuer die behandlung von allen leukaemieformen und neurotischen syndromen |
CH601227A5 (es) * | 1975-05-30 | 1978-06-30 | Nestle Sa | |
CH608790A5 (en) * | 1976-11-18 | 1979-01-31 | Nestle Sa | Process for separating serotonin from coffee waxes |
-
1983
- 1983-07-01 US US06/510,167 patent/US4506080A/en not_active Expired - Lifetime
-
1984
- 1984-04-26 AT AT86103841T patent/ATE38513T1/de not_active IP Right Cessation
- 1984-04-26 AT AT86103842T patent/ATE38514T1/de not_active IP Right Cessation
- 1984-04-26 DE DE8484104696T patent/DE3462794D1/de not_active Expired
- 1984-04-26 EP EP86103841A patent/EP0197389B1/en not_active Expired
- 1984-04-26 EP EP84104696A patent/EP0130303B1/en not_active Expired
- 1984-04-26 EP EP86103842A patent/EP0197390B1/en not_active Expired
- 1984-05-02 GB GB08411197A patent/GB2142622B/en not_active Expired
- 1984-05-03 IL IL71737A patent/IL71737A/xx unknown
- 1984-05-23 ZM ZM33/84A patent/ZM3384A1/xx unknown
- 1984-05-24 JP JP59103799A patent/JPS6025966A/ja active Granted
- 1984-06-29 OA OA58329A patent/OA07734A/xx unknown
- 1984-06-30 ES ES533890A patent/ES8602653A1/es not_active Expired
-
1985
- 1985-07-16 ES ES545230A patent/ES545230A0/es active Granted
- 1985-07-16 ES ES545232A patent/ES8603411A1/es not_active Expired
- 1985-07-16 ES ES545231A patent/ES8604142A1/es not_active Expired
- 1985-08-29 GB GB08521544A patent/GB2165838B/en not_active Expired
- 1985-08-29 GB GB08521543A patent/GB2165837B/en not_active Expired
-
1988
- 1988-07-12 JP JP63171971A patent/JPS6445363A/ja active Granted
- 1988-07-12 JP JP63171969A patent/JPS6445361A/ja active Granted
- 1988-07-12 JP JP63171970A patent/JPS6445362A/ja active Granted
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19971001 |