ES8101567A1 - Procedimiento de preparacion de nuevas trifluoroetilaminas n-sustituidas - Google Patents

Procedimiento de preparacion de nuevas trifluoroetilaminas n-sustituidas

Info

Publication number
ES8101567A1
ES8101567A1 ES487148A ES487148A ES8101567A1 ES 8101567 A1 ES8101567 A1 ES 8101567A1 ES 487148 A ES487148 A ES 487148A ES 487148 A ES487148 A ES 487148A ES 8101567 A1 ES8101567 A1 ES 8101567A1
Authority
ES
Spain
Prior art keywords
trifluoroethylamine
oxazolines
trifluorethylamines
lower alkyl
endowed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487148A
Other languages
English (en)
Other versions
ES487148A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of ES8101567A1 publication Critical patent/ES8101567A1/es
Publication of ES487148A0 publication Critical patent/ES487148A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/167Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing only fluorine as halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29Saturated compounds containing keto groups bound to rings
    • C07C49/327Saturated compounds containing keto groups bound to rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/48Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12Nitrogen atoms not forming part of a nitro radical
    • C07D239/14Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE TRIFLUOROETILAMINAS N-SUSTITUIDAS. CONSISTE EN CONDENSAR UNA TRIFLUOROETILAMINA DE FORMULA GENERAL (I) CON UN ISOCIANATO O UN ISOTIOCIANATO DE N-HALOGENO ALCOILO (A.C.N.-(CH2)''N-CH2 HAL, PARA FORMAR UNA W-HALOGENOALCOILUREA O TIOUREA. A CONTINUACION SE CICLIZA EL COMPUESTO OBTENIDO MEDIANTE CALENTAMIENTO EN UN COMPUESTO (II). EL COMPUESTO OBTENIDO (III) PUEDE SALIFICARSE MEDIANTE ADICION DE UN ACIDO MINERAL U ORGANICO, O PUEDE DESDOBLARSE EN SUS ISOMEROS OPTICOS MEDIANTE SALIFICACION EMPLEANDO UN ACIDO OPTICAMENTE ACITVO. *FORMULA* ACTIVIDAD HIPER-TENSIVA.
ES487148A 1978-12-20 1979-12-20 Procedimiento de preparacion de nuevas trifluoroetilaminas n-sustituidas Granted ES487148A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7835741A FR2444673A1 (fr) 1978-12-20 1978-12-20 Nouvelles trifluoroethylamines, leurs procedes d'obtention et leur emploi comme medicament

Publications (2)

Publication Number Publication Date
ES8101567A1 true ES8101567A1 (es) 1980-12-16
ES487148A0 ES487148A0 (es) 1980-12-16

Family

ID=9216327

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487148A Granted ES487148A0 (es) 1978-12-20 1979-12-20 Procedimiento de preparacion de nuevas trifluoroetilaminas n-sustituidas

Country Status (16)

Country Link
US (1) US4378366A (es)
JP (1) JPS5846516B2 (es)
AR (1) AR223997A1 (es)
AU (1) AU5399879A (es)
BE (1) BE880743A (es)
CA (1) CA1169859A (es)
DD (1) DD148053A5 (es)
DE (1) DE2951247A1 (es)
ES (1) ES487148A0 (es)
FR (1) FR2444673A1 (es)
GB (1) GB2044756B (es)
IL (1) IL59002A0 (es)
IT (1) IT1164915B (es)
NL (1) NL7909200A (es)
OA (1) OA06415A (es)
ZA (1) ZA796884B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3417411A1 (de) * 1983-06-30 1985-01-03 Canon K.K., Tokio/Tokyo Tintenherstellungssystem
US4802989A (en) * 1983-07-28 1989-02-07 Canon Kabushiki Kaisha System for purifying dye
DK302185A (da) * 1984-07-05 1986-01-06 Rolland Sa A 2-amino-oxazoliner samt fremgangsmaade til deres fremstilling
FR2669927B1 (fr) * 1990-11-29 1994-04-08 Adir Cie Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
AUPP020297A0 (en) * 1997-11-05 1997-11-27 University Of Melbourne, The A novel receptor, and compounds which bind thereto
US6265616B1 (en) * 1999-02-08 2001-07-24 Honeywell International Inc. Manufacture of trifluorisopropylamine
US6297384B1 (en) 1999-12-21 2001-10-02 The Procter & Gamble Company Process for the preparation of 1,2,4-thiadiazoles
JP2005161674A (ja) * 2003-12-02 2005-06-23 Canon Inc 画像形成装置、画像形成システム、課金処理方法及びプログラム
JP5902575B2 (ja) * 2012-07-20 2016-04-13 国立大学法人お茶の水女子大学 光学活性含フッ素アミン化合物の製造方法並びに光学活性含フッ素アミン化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670751A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-2-oxazolinen
DE1670753A1 (de) * 1966-09-27 1970-07-16 Bayer Ag Verfahren zur Herstellung von 2-Cycloalkylaminooxazolinen
DE1670754A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylimino-oxazolidinen
DE1670752A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-oxazolinen
DE2253554C3 (de) * 1972-11-02 1981-02-12 Hoechst Ag, 6000 Frankfurt 2-Amino-2-oxazoline, Verfahren zu ihrer Herstellung und deren Verwendung zur Erhöhung des Blutdrucks
US4102890A (en) * 1972-12-28 1978-07-25 Science-Union Et Cie, Societe Francaise De Recherche Medicale 2-Amino oxazolines and process for making the same
GB1453703A (en) * 1972-12-28 1976-10-27 Science Union & Cie Substituted cyclopropylmethylamines processes for their preparation and pharmaceutical compositions containing them
GB1475513A (en) * 1974-06-20 1977-06-01 Science Union & Cie Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them
ES442992A1 (es) * 1974-12-02 1977-08-01 Scherico Ltd Un procedimiento para preparar 2-anilino-oxazolinas.
FR2358890A1 (fr) * 1976-05-24 1978-02-17 Science Union & Cie Nouvelles aryl trifluoroethylamines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
DE2710170A1 (de) * 1977-03-09 1978-09-14 Byk Gulden Lomberg Chem Fab Neue geminal substituierte cycloalkane, verfahren zu deren herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
GB2044756A (en) 1980-10-22
NL7909200A (nl) 1980-06-24
BE880743A (fr) 1980-06-19
GB2044756B (en) 1982-12-22
IT7951130A0 (it) 1979-12-19
OA06415A (fr) 1981-09-30
US4378366A (en) 1983-03-29
DD148053A5 (de) 1981-05-06
JPS5846516B2 (ja) 1983-10-17
JPS5592373A (en) 1980-07-12
DE2951247A1 (de) 1980-07-03
IT1164915B (it) 1987-04-15
AU5399879A (en) 1980-06-26
ZA796884B (en) 1980-11-26
DE2951247C2 (es) 1988-03-10
CA1169859A (fr) 1984-06-26
AR223997A1 (es) 1981-10-15
FR2444673B1 (es) 1981-04-17
ES487148A0 (es) 1980-12-16
IL59002A0 (en) 1980-03-31
FR2444673A1 (fr) 1980-07-18

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