ES479396A1 - Procedimiento para la preparacion de derivados de carbazolil-(4)-oxi-propanolamina. - Google Patents

Procedimiento para la preparacion de derivados de carbazolil-(4)-oxi-propanolamina.

Info

Publication number
ES479396A1
ES479396A1 ES479396A ES479396A ES479396A1 ES 479396 A1 ES479396 A1 ES 479396A1 ES 479396 A ES479396 A ES 479396A ES 479396 A ES479396 A ES 479396A ES 479396 A1 ES479396 A1 ES 479396A1
Authority
ES
Spain
Prior art keywords
hydrogen
lower alkyl
carbazolyl
oxypropanolamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES479396A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6036838&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES479396(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES479396A1 publication Critical patent/ES479396A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la preparación de derivados de carbazoil- (4)-oxi-propanolamina de la fórmula general ( I) ** (formula- 01)** en la que R1 significa hidrogeno, un grupo alcanoilo inferior o un grupo aroilo; R2 significa hidrógeno, un grupo alcohilo inferior o un grupo aralcohilo; R3 significa hidrógeno o un grupo alcohilo inferior; R4 significa hidrogeno o un grupo -CH2-, un átomo de oxigeno o un atomo de azufre, Ar significa un radical arilo monociclico o biciclico o piridina; y R5 y R6, que pueden ser iguales o diferentes, significan en cada caso hidrogeno, halogeno, un grupo alcohilo inferior, un grupo aminocarbonilo, un grupo hidroxi, un grupo alcoxi inferior, un grupo aralcohiloxi, un grupo alcohilmercapto inferior, un grupo alcohilsulfino inferior, un grupo alcohildulfonilo inferior, o también en común un grupo metilendioxi,
ES479396A 1978-04-13 1979-04-06 Procedimiento para la preparacion de derivados de carbazolil-(4)-oxi-propanolamina. Expired ES479396A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782815926 DE2815926A1 (de) 1978-04-13 1978-04-13 Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES479396A1 true ES479396A1 (es) 1980-04-16

Family

ID=6036838

Family Applications (1)

Application Number Title Priority Date Filing Date
ES479396A Expired ES479396A1 (es) 1978-04-13 1979-04-06 Procedimiento para la preparacion de derivados de carbazolil-(4)-oxi-propanolamina.

Country Status (23)

Country Link
US (1) US4503067A (es)
EP (1) EP0004920B1 (es)
JP (2) JPS54157558A (es)
AT (1) AT375639B (es)
AU (1) AU522975B2 (es)
BG (1) BG61419B2 (es)
CA (1) CA1129416A (es)
CS (2) CS227007B2 (es)
DD (1) DD143607A5 (es)
DE (2) DE2815926A1 (es)
DK (1) DK154555C (es)
ES (1) ES479396A1 (es)
FI (1) FI70406C (es)
HK (1) HK2385A (es)
HU (1) HU179433B (es)
IL (1) IL57020A (es)
LT (1) LT2628B (es)
LU (1) LU88320I2 (es)
MX (1) MX9203380A (es)
NL (1) NL930110I2 (es)
SG (1) SG52284G (es)
SU (1) SU810079A3 (es)
ZA (1) ZA791732B (es)

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AT336176B (de) * 1971-12-10 1977-04-25 Sandoz Ag Verfahren zur herstellung eines pharmazeutischen praparates
US3975398A (en) * 1973-08-01 1976-08-17 Boehringer Mannheim G.M.B.H. 9-Substituted 3-aminocarbazole compounds
DE2339396C2 (de) * 1973-08-03 1984-06-28 Boehringer Mannheim Gmbh, 6800 Mannheim N-substituierte 1-Amino-3-phenoxypropan-2-ole, deren Salze, Verfahren zu deren Herstellung sowie Arzneimittel, die diese Verbindungen enthalten
DE2424523A1 (de) * 1974-05-21 1975-12-11 Boehringer Mannheim Gmbh Neue 1,2,3,4-tetrahydrocarbazol-derivate und verfahren zu deren herstellung
US4076829A (en) * 1974-11-16 1978-02-28 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
DE2454406A1 (de) * 1974-11-16 1976-05-20 Boehringer Mannheim Gmbh Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4152446A (en) * 1974-11-16 1979-05-01 Boehringer Mannheim Gmbh Aminopropanol compounds and compositions for the treatment of cardiac and circulatory diseases
GB1508208A (en) * 1975-12-05 1978-04-19 Ici Ltd Amide derivatives
US4115409A (en) * 1975-12-05 1978-09-19 Imperial Chemical Industries Limited Alkanolamine derivatives

Also Published As

Publication number Publication date
JPS54157558A (en) 1979-12-12
JPS63258416A (ja) 1988-10-25
AT375639B (de) 1984-08-27
IL57020A (en) 1982-07-30
ZA791732B (en) 1980-05-28
DK154555B (da) 1988-11-28
SG52284G (en) 1985-03-29
HK2385A (en) 1985-01-18
IL57020A0 (en) 1979-07-25
LT2628B (lt) 1994-04-25
CS420091A3 (en) 1992-04-15
FI70406C (fi) 1986-09-19
JPH0123462B2 (es) 1989-05-02
EP0004920A1 (de) 1979-10-31
MX9203380A (es) 1992-09-01
SU810079A3 (ru) 1981-02-28
FI791142A (fi) 1979-10-14
LU88320I2 (de) 1994-05-04
NL930110I2 (nl) 1994-12-01
DD143607A5 (de) 1980-09-03
FI70406B (fi) 1986-03-27
AU4582079A (en) 1979-10-18
DE2960553D1 (en) 1981-11-05
EP0004920B1 (de) 1981-08-05
NL930110I1 (nl) 1993-10-18
DE2815926A1 (de) 1979-10-18
DK154555C (da) 1989-06-19
US4503067A (en) 1985-03-05
ATA276279A (de) 1984-01-15
CS227007B2 (en) 1984-04-16
HU179433B (en) 1982-10-28
AU522975B2 (en) 1982-07-08
DK141979A (da) 1979-10-14
CA1129416A (en) 1982-08-10
BG61419B2 (bg) 1997-07-31

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