ES2185817T3 - Formas de dosificacion farmaceutica oral que comprenden un inhibidor de las bombas de protones y un agente antiacido o alginato. - Google Patents
Formas de dosificacion farmaceutica oral que comprenden un inhibidor de las bombas de protones y un agente antiacido o alginato.Info
- Publication number
- ES2185817T3 ES2185817T3 ES96944726T ES96944726T ES2185817T3 ES 2185817 T3 ES2185817 T3 ES 2185817T3 ES 96944726 T ES96944726 T ES 96944726T ES 96944726 T ES96944726 T ES 96944726T ES 2185817 T3 ES2185817 T3 ES 2185817T3
- Authority
- ES
- Spain
- Prior art keywords
- inhibitor
- protons
- alginate
- anticide
- pumps
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
FORMA FARMACEUTICA DE DOSIFICACION ORAL QUE CONTIENE UN INHIBIDOR DE LA BOMBA DE PROTONES SENSIBLE AL ACIDO Y UNO O MAS AGENTES ANTIACIDOS O UN ALGINATO EN FORMULACION FIJA, EN LA QUE EL INHIBIDOR DE LA BOMBA DE PROTONES ESTA PROTEGIDO POR UNA CUBIERTA ENTERICA Y UNA CAPA OPCIONAL DE SEPARACION ENTRE EL INHIBIDOR DE LA BOMBA DE PROTONES Y LA CUBIERTA ENTERICA. LA FORMULACION FIJA ADOPTA LA FORMA DE COMPRIMIDOS MULTICAPA, SOBRES O TABLETAS EN MULTIPLES UNIDADES. LA FORMA DE DOSIFICACION EN UNIDADES MULTIPLES ES LA PREFERIDA. LA NUEVA FORMULACION FIJA RESULTA ESPECIALMENTE UTIL EN EL TRATAMIENTO DE LOS TRASTORNOS ASOCIADOS CON LA DISPEPSIA, COMO LA PIROSIS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9600071 | 1996-01-08 | ||
SE9600071A SE9600071D0 (sv) | 1996-01-08 | 1996-01-08 | New oral formulation of two active ingredients I |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2185817T3 true ES2185817T3 (es) | 2003-05-01 |
ES2185817T5 ES2185817T5 (es) | 2009-11-24 |
Family
ID=20400969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96944726T Expired - Lifetime ES2185817T5 (es) | 1996-01-08 | 1996-12-20 | Formas de dosificacion farmaceutica oral que comprenden un inhibidor de las bombas de protones y un agente antiacido o alginato. |
Country Status (35)
Country | Link |
---|---|
US (1) | US6183776B1 (es) |
EP (1) | EP0813424B2 (es) |
JP (1) | JPH11501950A (es) |
KR (1) | KR100490075B1 (es) |
CN (1) | CN1080125C (es) |
AR (1) | AR005281A1 (es) |
AT (1) | ATE228009T1 (es) |
AU (1) | AU712669B2 (es) |
BR (1) | BR9607350B1 (es) |
CA (1) | CA2213996C (es) |
CZ (1) | CZ293583B6 (es) |
DE (1) | DE69624907T3 (es) |
DK (1) | DK0813424T4 (es) |
EE (1) | EE04002B1 (es) |
EG (1) | EG23821A (es) |
ES (1) | ES2185817T5 (es) |
HK (2) | HK1001763A1 (es) |
HU (1) | HU229153B1 (es) |
IL (1) | IL121651A (es) |
IS (1) | IS2716B (es) |
MX (1) | MX9706785A (es) |
MY (1) | MY116091A (es) |
NO (1) | NO326656B1 (es) |
NZ (1) | NZ325977A (es) |
PL (1) | PL187075B1 (es) |
PT (1) | PT813424E (es) |
RU (1) | RU2179453C2 (es) |
SA (1) | SA97170553B1 (es) |
SE (1) | SE9600071D0 (es) |
SK (1) | SK283695B6 (es) |
TR (1) | TR199700916T1 (es) |
TW (1) | TW464514B (es) |
UA (1) | UA45392C2 (es) |
WO (1) | WO1997025066A1 (es) |
ZA (1) | ZA9610935B (es) |
Families Citing this family (124)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
SE9600071D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients I |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
JP2001509791A (ja) * | 1996-11-27 | 2001-07-24 | ザ、プロクター、エンド、ギャンブル、カンパニー | 胃腸障害の治療用組成物及び方法 |
MX9703918A (es) * | 1997-05-28 | 1998-11-30 | J Marshall M D Barry | Procedimiento para preparar un producto farmaceutico reactivo para deteccion de desorden gastrointestinal causado por bacteria en el tracto gastrointestinal superior. |
SE510650C2 (sv) * | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
JP2001513570A (ja) * | 1997-08-25 | 2001-09-04 | ザ、プロクター、エンド、ギャンブル、カンパニー | 上部胃腸管不調治療用複合製剤 |
ATE303809T1 (de) * | 1997-12-08 | 2005-09-15 | Altana Pharma Ag | Orale verabreichungsform enthaltend einen protonenpumpeninhbitor (z.b. pantoprazole) |
SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
SE9704869D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulaton II |
FR2774906B1 (fr) * | 1998-02-13 | 2000-05-12 | Rhodia Chimie Sa | Systeme d'encapsulation a coeur organique et a ecorce minerale a base d'hydroxycarbonate d'aluminium et son procede de preparation |
CN1195500C (zh) * | 1998-05-18 | 2005-04-06 | 武田药品工业株式会社 | 可口腔崩解的片剂 |
UA69413C2 (uk) * | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
US7122207B2 (en) | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
CA2581111A1 (en) | 1998-07-28 | 2000-02-10 | Takeda Pharmaceutical Company Limited | Rapidly disintegrable solid preparation |
SE9803772D0 (sv) * | 1998-11-05 | 1998-11-05 | Astra Ab | Pharmaceutical formulation |
BR0011180A (pt) * | 1999-03-29 | 2002-07-09 | American Home Prod | Sistema e métodos de revestimento para aplicação a unidades de dosagem farmacêutica sólidas e composição |
JP2003504338A (ja) * | 1999-07-12 | 2003-02-04 | スミスクライン・ビーチャム・コーポレイション | 胸やけの処置法 |
JP4081273B2 (ja) | 1999-10-20 | 2008-04-23 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ベンズイミダゾール系化合物安定化方法 |
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US20020064555A1 (en) * | 2000-09-29 | 2002-05-30 | Dan Cullen | Proton pump inhibitor formulation |
US20020192299A1 (en) * | 2000-12-28 | 2002-12-19 | Rajneesh Taneja | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination |
SE0101379D0 (sv) * | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
NZ530511A (en) * | 2001-07-16 | 2005-06-24 | Astrazeneca Ab | A tablet for treating disorders of the gastrointestinal tract comprising a proton pump inhibitor and at least one antacid that has a barrier layer to cover an enteric coating film |
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1996
- 1996-01-08 SE SE9600071A patent/SE9600071D0/xx unknown
- 1996-12-20 DE DE69624907T patent/DE69624907T3/de not_active Expired - Lifetime
- 1996-12-20 SK SK1169-97A patent/SK283695B6/sk not_active IP Right Cessation
- 1996-12-20 NZ NZ325977A patent/NZ325977A/xx not_active IP Right Cessation
- 1996-12-20 PL PL96322175A patent/PL187075B1/pl not_active IP Right Cessation
- 1996-12-20 WO PCT/SE1996/001737 patent/WO1997025066A1/en active IP Right Grant
- 1996-12-20 DK DK96944726T patent/DK0813424T4/da active
- 1996-12-20 RU RU97116726/14A patent/RU2179453C2/ru not_active IP Right Cessation
- 1996-12-20 IL IL12165196A patent/IL121651A/xx not_active IP Right Cessation
- 1996-12-20 MX MX9706785A patent/MX9706785A/es not_active IP Right Cessation
- 1996-12-20 KR KR1019970706236A patent/KR100490075B1/ko not_active IP Right Cessation
- 1996-12-20 PT PT96944726T patent/PT813424E/pt unknown
- 1996-12-20 CZ CZ19972747A patent/CZ293583B6/cs not_active IP Right Cessation
- 1996-12-20 EE EE9700192A patent/EE04002B1/xx not_active IP Right Cessation
- 1996-12-20 BR BRPI9607350-0A patent/BR9607350B1/pt not_active IP Right Cessation
- 1996-12-20 UA UA97104949A patent/UA45392C2/uk unknown
- 1996-12-20 AT AT96944726T patent/ATE228009T1/de active
- 1996-12-20 HU HU9904024A patent/HU229153B1/hu not_active IP Right Cessation
- 1996-12-20 CA CA002213996A patent/CA2213996C/en not_active Expired - Fee Related
- 1996-12-20 JP JP9525131A patent/JPH11501950A/ja active Pending
- 1996-12-20 US US08/750,934 patent/US6183776B1/en not_active Expired - Lifetime
- 1996-12-20 ES ES96944726T patent/ES2185817T5/es not_active Expired - Lifetime
- 1996-12-20 EP EP96944726A patent/EP0813424B2/en not_active Expired - Lifetime
- 1996-12-20 CN CN96193594A patent/CN1080125C/zh not_active Expired - Fee Related
- 1996-12-20 AU AU13241/97A patent/AU712669B2/en not_active Ceased
- 1996-12-20 TR TR97/00916T patent/TR199700916T1/xx unknown
- 1996-12-26 AR ARP960105899A patent/AR005281A1/es not_active Application Discontinuation
- 1996-12-27 TW TW085116139A patent/TW464514B/zh not_active IP Right Cessation
- 1996-12-30 ZA ZA9610935A patent/ZA9610935B/xx unknown
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1997
- 1997-01-07 EG EG1897A patent/EG23821A/xx active
- 1997-01-07 MY MYPI97000065A patent/MY116091A/en unknown
- 1997-01-15 SA SA97170553A patent/SA97170553B1/ar unknown
- 1997-08-20 IS IS4548A patent/IS2716B/is unknown
- 1997-09-04 NO NO19974071A patent/NO326656B1/no not_active IP Right Cessation
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1998
- 1998-02-05 HK HK98100847A patent/HK1001763A1/xx not_active IP Right Cessation
- 1998-11-06 HK HK98111792A patent/HK1017992A1/xx not_active IP Right Cessation
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