ES2087056T3 - 2-pirimidinaminas sustituidas en las posiciones 4, 5 y 6. - Google Patents

2-pirimidinaminas sustituidas en las posiciones 4, 5 y 6.

Info

Publication number
ES2087056T3
ES2087056T3 ES87100277T ES87100277T ES2087056T3 ES 2087056 T3 ES2087056 T3 ES 2087056T3 ES 87100277 T ES87100277 T ES 87100277T ES 87100277 T ES87100277 T ES 87100277T ES 2087056 T3 ES2087056 T3 ES 2087056T3
Authority
ES
Spain
Prior art keywords
substituted
pirimidinamines
positions
pyrimidinamines
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87100277T
Other languages
English (en)
Inventor
Lawrence Wayne Torley
Bernard B Johnson
John Paul Dusza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25224278&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2087056(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2087056T3 publication Critical patent/ES2087056T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

ESTA PREPARACION DESCRIBE NUEVAS 2-PIRIMIDINAMINAS 4,5,6 SUSTITUIDAS-N-(FENILSUSTITUIDAS) QUE TIENEN ACTIVIDAD ANTIASMATICA.
ES87100277T 1986-01-13 1987-01-12 2-pirimidinaminas sustituidas en las posiciones 4, 5 y 6. Expired - Lifetime ES2087056T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81795186A 1986-01-13 1986-01-13

Publications (1)

Publication Number Publication Date
ES2087056T3 true ES2087056T3 (es) 1996-07-16

Family

ID=25224278

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87100277T Expired - Lifetime ES2087056T3 (es) 1986-01-13 1987-01-12 2-pirimidinaminas sustituidas en las posiciones 4, 5 y 6.

Country Status (18)

Country Link
EP (1) EP0233461B2 (es)
JP (1) JPH0780857B2 (es)
KR (1) KR900004693B1 (es)
AT (1) ATE135699T1 (es)
AU (2) AU591223B2 (es)
BR (1) BR1100989A (es)
CA (1) CA1320201C (es)
DE (1) DE3751742T3 (es)
DK (1) DK171251B1 (es)
ES (1) ES2087056T3 (es)
FI (1) FI91150C (es)
GR (1) GR3019455T3 (es)
HU (1) HU198708B (es)
IE (1) IE74202B1 (es)
NZ (1) NZ218924A (es)
PH (1) PH25056A (es)
SG (1) SG47583A1 (es)
ZA (1) ZA87219B (es)

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US5162328A (en) * 1991-12-31 1992-11-10 American Cyanamid Company N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine and pharmacologically acceptable salts
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
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Also Published As

Publication number Publication date
DE3751742T3 (de) 2002-11-21
DE3751742D1 (de) 1996-04-25
AU621461B2 (en) 1992-03-12
DK15187A (da) 1987-07-14
KR870007154A (ko) 1987-08-17
JPS62223177A (ja) 1987-10-01
DE3751742T2 (de) 1996-11-21
AU6751887A (en) 1987-07-16
IE870074L (en) 1987-07-13
GR3019455T3 (en) 1996-06-30
EP0233461A2 (en) 1987-08-26
FI870113A0 (fi) 1987-01-13
KR900004693B1 (ko) 1990-07-02
HUT43582A (en) 1987-11-30
NZ218924A (en) 1990-04-26
FI91150C (fi) 1994-05-25
EP0233461B1 (en) 1996-03-20
IE74202B1 (en) 1997-07-16
AU5057890A (en) 1990-07-26
ATE135699T1 (de) 1996-04-15
EP0233461A3 (en) 1988-05-25
SG47583A1 (en) 1998-04-17
BR1100989A (pt) 1999-11-09
CA1320201C (en) 1993-07-13
EP0233461B2 (en) 2002-05-29
FI870113A (fi) 1987-07-14
JPH0780857B2 (ja) 1995-08-30
DK171251B1 (da) 1996-08-12
DK15187D0 (da) 1987-01-13
FI91150B (fi) 1994-02-15
ZA87219B (en) 1987-08-26
PH25056A (en) 1991-01-28
AU591223B2 (en) 1989-11-30
HU198708B (en) 1989-11-28

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