EE04218B1 - Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod - Google Patents

Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod

Info

Publication number
EE04218B1
EE04218B1 EEP200000096A EEP200000096A EE04218B1 EE 04218 B1 EE04218 B1 EE 04218B1 EE P200000096 A EEP200000096 A EE P200000096A EE P200000096 A EEP200000096 A EE P200000096A EE 04218 B1 EE04218 B1 EE 04218B1
Authority
EE
Estonia
Prior art keywords
pharmaceutical preparation
manufacture
microcrystalline cellulose
excipient
active ingredient
Prior art date
Application number
EEP200000096A
Other languages
English (en)
Estonian (et)
Inventor
Lehtola Veli-Matti
Susanne Rantala Eeva-Maria
Tapani Rantala Pertti
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of EE200000096A publication Critical patent/EE200000096A/xx
Publication of EE04218B1 publication Critical patent/EE04218B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
EEP200000096A 1997-09-19 1998-09-18 Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod EE04218B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI973733A FI109088B (fi) 1997-09-19 1997-09-19 Tabletti ja menetelmä sen valmistamiseksi
PCT/FI1998/000735 WO1999015155A1 (en) 1997-09-19 1998-09-18 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Publications (2)

Publication Number Publication Date
EE200000096A EE200000096A (et) 2000-12-15
EE04218B1 true EE04218B1 (et) 2004-02-16

Family

ID=8549561

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000096A EE04218B1 (et) 1997-09-19 1998-09-18 Toimeainena klodronaati ja ekstsipiendina ränistatud mikrokristallilist tselluloosi sisaldav farmatseutiline preparaat ning farmatseutilise preparaadi tootmismeetod

Country Status (31)

Country Link
EP (1) EP1027037B1 (fi)
JP (1) JP3589977B2 (fi)
KR (1) KR20010024184A (fi)
CN (1) CN1124130C (fi)
AT (1) ATE255410T1 (fi)
AU (1) AU737738B2 (fi)
BG (1) BG64886B1 (fi)
BR (1) BR9812480A (fi)
CA (1) CA2301185C (fi)
CZ (1) CZ298675B6 (fi)
DE (3) DE69820287T2 (fi)
DK (1) DK1027037T3 (fi)
EA (1) EA002331B1 (fi)
EE (1) EE04218B1 (fi)
ES (1) ES2212341T3 (fi)
FI (1) FI109088B (fi)
HK (1) HK1031325A1 (fi)
HR (1) HRP20000142B1 (fi)
HU (1) HU226118B1 (fi)
ID (1) ID24423A (fi)
IL (1) IL135130A (fi)
IS (1) IS5404A (fi)
NO (1) NO327728B1 (fi)
NZ (1) NZ503766A (fi)
PL (1) PL191166B1 (fi)
PT (1) PT1027037E (fi)
SI (1) SI1027037T1 (fi)
SK (1) SK284088B6 (fi)
TR (1) TR200000722T2 (fi)
UA (1) UA73078C2 (fi)
WO (1) WO1999015155A1 (fi)

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US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
ATE304856T1 (de) * 2000-06-20 2005-10-15 Novartis Pharma Gmbh Methode zur verabreichung von biphosphonaten
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WO2003047551A1 (en) * 2001-11-29 2003-06-12 Penwest Pharmaceutical Company Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2279731B1 (en) * 2008-04-23 2012-12-12 Farmasierra Manufacturing, S.L. Improved pharmaceutical composition containing ibuprofen and codeine
US8603527B2 (en) * 2010-10-25 2013-12-10 Signal Pharmaceuticals, Llc Pharmaceutical formulations of a substituted diaminopurine
SG11201404705YA (en) * 2012-02-07 2014-10-30 Biogen Idec Inc Pharmaceutical compositions containing dimethyl fumarate
US10493085B2 (en) 2012-05-14 2019-12-03 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
US9211257B2 (en) 2012-05-14 2015-12-15 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
US9999628B2 (en) 2012-05-14 2018-06-19 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
US10111837B2 (en) 2012-05-14 2018-10-30 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds
US8802658B2 (en) * 2012-05-14 2014-08-12 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
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US10028908B2 (en) 2012-05-14 2018-07-24 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9655908B2 (en) 2012-05-14 2017-05-23 Antecip Bioventures Ii Llc Neridronic acid molecular complex for treating complex regional pain syndrome
US9782421B1 (en) 2012-05-14 2017-10-10 Antecip Bioventures Ii Llc Neridronic acid molecular complex for treating complex regional pain syndrome
US10016445B2 (en) 2012-05-14 2018-07-10 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9694023B2 (en) 2012-05-14 2017-07-04 Antecip Bioventures Ii Llc Methods for the safe administration of imidazole or imidazolium compounds
US9616078B2 (en) 2012-05-14 2017-04-11 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US11654152B2 (en) 2012-05-14 2023-05-23 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US10463682B2 (en) 2012-05-14 2019-11-05 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
US9867839B2 (en) 2012-05-14 2018-01-16 Antecip Bioventures Ii Llc Osteoclast inhibitors for joint conditions
US9877977B2 (en) 2012-05-14 2018-01-30 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9770457B2 (en) 2012-05-14 2017-09-26 Antecip Bioventures Ii Llc Neridronic acid for treating bone marrow lesion
US20150051175A1 (en) * 2012-05-14 2015-02-19 Antecip Bioventures Ii Llc Co-Administration of Steroids and Zoledronic Acid to Prevent and Treat Pain
US9827256B2 (en) 2014-05-27 2017-11-28 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating lower back pain
US9675626B2 (en) 2012-05-14 2017-06-13 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10173986B2 (en) 2012-05-14 2019-01-08 Antecip Bioventures Ii Llc Methods for the safe administration of imidazole or imidazolium compounds
US9717747B2 (en) 2012-05-14 2017-08-01 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
US10028969B2 (en) 2012-05-14 2018-07-24 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9943531B2 (en) 2014-08-08 2018-04-17 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
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US10034890B2 (en) 2012-05-14 2018-07-31 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9795622B2 (en) 2012-05-14 2017-10-24 Antecip Bioventures Ii Llc Neridronic acid for treating pain associated with a joint
US9956237B2 (en) 2012-05-14 2018-05-01 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
US9949993B2 (en) 2012-05-14 2018-04-24 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
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US10016446B2 (en) 2012-05-14 2018-07-10 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone
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US10092581B2 (en) 2014-05-15 2018-10-09 Antecip Bioventures Ii Llc Osteoclast inhibitors such as zoledronic acid for low back pain treatment
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US8865757B1 (en) 2014-05-28 2014-10-21 Antecip Bioventures Ii Llp Therapeutic compositions comprising imidazole and imidazolium compounds
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US10413561B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
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CN102698280B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 塔格糖片剂赋形剂、药物片剂及药物片剂的制备方法
CN102697744B (zh) * 2012-05-29 2013-11-27 安吉东来药用辅料有限责任公司 阿洛糖片剂赋形剂、药物片剂及药物片剂的制备方法
CN102688206B (zh) * 2012-05-29 2014-08-20 石药集团中奇制药技术（石家庄）有限公司 一种匹伐他汀钙片及其制备方法
CN102671206B (zh) * 2012-05-29 2013-07-10 安吉东来药用辅料有限责任公司 低聚果糖片剂赋形剂、药物片剂及药物片剂的制备方法
US9127069B1 (en) 2014-06-11 2015-09-08 Antecip Bioventures LLC Compositions comprising rank/rankl antagonists and related compounds for treating pain
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CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
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JP6995058B2 (ja) 2016-04-01 2022-02-21 シグナル ファーマシューティカルズ，エルエルシー （１ｓ，４ｓ）－４－（２－（（（３ｓ，４ｒ）－３－フルオロテトラヒドロ－２ｈ－ピラン－４－イル）アミノ）－８－（（２，４，６－トリクロロフェニル）アミノ）－９ｈ－プリン－９－イル）－１－メチルクロロヘキサン－１－カルボキサミドの固体形態及びその使用方法
JP2020536100A (ja) 2017-10-04 2020-12-10 セルジーン コーポレイション シス−４−［２−｛［（３ｓ，４ｒ）−３−フルオロキサン−４−イル］アミノ｝−８−（２，４，６−トリクロロアニリノ）−９ｈ−プリン−９−イル］−１−メチルシクロヘキサン−１−カルボキサミドの製造プロセス
KR20200062270A (ko) 2017-10-04 2020-06-03 셀진 코포레이션 시스-4-[2-｛[(3s,4r)-3-플루오로옥산-4-일]아미노｝-8-(2,4,6-트리클로로아닐리노)-9h-퓨린-9-일]-1-메틸시클로헥산-1-카르복스아미드의 조성물 및 이용 방법
CN110787140A (zh) * 2018-08-01 2020-02-14 北京万全德众医药生物技术有限公司 比拉斯汀片剂及其制备方法

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KR20010024184A (ko) 2001-03-26
JP2001517616A (ja) 2001-10-09
DE1027037T1 (de) 2002-11-28
CN1270516A (zh) 2000-10-18
BR9812480A (pt) 2000-09-26
EP1027037A1 (en) 2000-08-16
JP3589977B2 (ja) 2004-11-17
FI109088B (fi) 2002-05-31
WO1999015155A1 (en) 1999-04-01
HK1031325A1 (en) 2001-06-15
SK3932000A3 (en) 2000-11-07
EE200000096A (et) 2000-12-15
CZ298675B6 (cs) 2007-12-19
CZ2000787A3 (cs) 2000-08-16
EP1027037B1 (en) 2003-12-03
UA73078C2 (uk) 2005-06-15
DE69820287T2 (de) 2004-10-14
HUP0004383A3 (en) 2006-06-28
FI973733A (fi) 1999-03-20
EA002331B1 (ru) 2002-04-25
CN1124130C (zh) 2003-10-15
HUP0004383A2 (hu) 2001-08-28
CA2301185A1 (en) 1999-04-01
HRP20000142A2 (en) 2000-06-30
HRP20000142B1 (en) 2004-06-30
IS5404A (is) 2000-03-14
ES2212341T3 (es) 2004-07-16
DE29824938U1 (de) 2003-07-31
BG64886B1 (bg) 2006-08-31
SK284088B6 (sk) 2004-09-08
BG104265A (en) 2000-11-30
CA2301185C (en) 2006-11-28
NO20001417D0 (no) 2000-03-17
ATE255410T1 (de) 2003-12-15
SI1027037T1 (en) 2004-04-30
NO20001417L (no) 2000-05-19
ID24423A (id) 2000-07-20
PT1027037E (pt) 2004-04-30
IL135130A (en) 2004-09-27
HU226118B1 (en) 2008-04-28
AU737738B2 (en) 2001-08-30
DK1027037T3 (da) 2004-03-15
EA200000317A1 (ru) 2000-10-30
IL135130A0 (en) 2001-05-20
PL191166B1 (pl) 2006-03-31
TR200000722T2 (tr) 2000-11-21
AU9268598A (en) 1999-04-12
FI973733A0 (fi) 1997-09-19
NZ503766A (en) 2002-02-01
NO327728B1 (no) 2009-09-14
DE69820287D1 (de) 2004-01-15
PL339290A1 (en) 2000-12-04

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