DK1027037T3 - Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens - Google Patents

Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens

Info

Publication number
DK1027037T3
DK1027037T3 DK98945336T DK98945336T DK1027037T3 DK 1027037 T3 DK1027037 T3 DK 1027037T3 DK 98945336 T DK98945336 T DK 98945336T DK 98945336 T DK98945336 T DK 98945336T DK 1027037 T3 DK1027037 T3 DK 1027037T3
Authority
DK
Denmark
Prior art keywords
microcrystalline cellulose
excipient
silicified microcrystalline
active ingredient
pharmaceutical preparation
Prior art date
Application number
DK98945336T
Other languages
English (en)
Inventor
Eeva-Maria Susanne Rantala
Pertti Tapani Rantala
Veli-Matti Lehtola
Original Assignee
Schering Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Oy filed Critical Schering Oy
Application granted granted Critical
Publication of DK1027037T3 publication Critical patent/DK1027037T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
DK98945336T 1997-09-19 1998-09-18 Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens DK1027037T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI973733A FI109088B (fi) 1997-09-19 1997-09-19 Tabletti ja menetelmä sen valmistamiseksi
PCT/FI1998/000735 WO1999015155A1 (en) 1997-09-19 1998-09-18 Pharmaceutical preparation comprising clodronate as active ingredient and silicified microcrystalline cellulose as excipient

Publications (1)

Publication Number Publication Date
DK1027037T3 true DK1027037T3 (da) 2004-03-15

Family

ID=8549561

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98945336T DK1027037T3 (da) 1997-09-19 1998-09-18 Farmaceutisk præparat som indeholder clodronat som aktiv ingrediens og forkislet mikrokrystallinsk cellulose som excipiens

Country Status (31)

Country Link
EP (1) EP1027037B1 (da)
JP (1) JP3589977B2 (da)
KR (1) KR20010024184A (da)
CN (1) CN1124130C (da)
AT (1) ATE255410T1 (da)
AU (1) AU737738B2 (da)
BG (1) BG64886B1 (da)
BR (1) BR9812480A (da)
CA (1) CA2301185C (da)
CZ (1) CZ298675B6 (da)
DE (3) DE69820287T2 (da)
DK (1) DK1027037T3 (da)
EA (1) EA002331B1 (da)
EE (1) EE04218B1 (da)
ES (1) ES2212341T3 (da)
FI (1) FI109088B (da)
HK (1) HK1031325A1 (da)
HR (1) HRP20000142B1 (da)
HU (1) HU226118B1 (da)
ID (1) ID24423A (da)
IL (1) IL135130A (da)
IS (1) IS5404A (da)
NO (1) NO327728B1 (da)
NZ (1) NZ503766A (da)
PL (1) PL191166B1 (da)
PT (1) PT1027037E (da)
SI (1) SI1027037T1 (da)
SK (1) SK284088B6 (da)
TR (1) TR200000722T2 (da)
UA (1) UA73078C2 (da)
WO (1) WO1999015155A1 (da)

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US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
ATE304856T1 (de) * 2000-06-20 2005-10-15 Novartis Pharma Gmbh Methode zur verabreichung von biphosphonaten
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US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
WO2003047551A1 (en) * 2001-11-29 2003-06-12 Penwest Pharmaceutical Company Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
US20040109889A1 (en) 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2279731B1 (en) * 2008-04-23 2012-12-12 Farmasierra Manufacturing, S.L. Improved pharmaceutical composition containing ibuprofen and codeine
US8603527B2 (en) * 2010-10-25 2013-12-10 Signal Pharmaceuticals, Llc Pharmaceutical formulations of a substituted diaminopurine
SG11201404705YA (en) * 2012-02-07 2014-10-30 Biogen Idec Inc Pharmaceutical compositions containing dimethyl fumarate
US10493085B2 (en) 2012-05-14 2019-12-03 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
US9211257B2 (en) 2012-05-14 2015-12-15 Antecip Bioventures Ii Llc Osteoclast inhibitors for knee conditions
US9999628B2 (en) 2012-05-14 2018-06-19 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
US10111837B2 (en) 2012-05-14 2018-10-30 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds
US8802658B2 (en) * 2012-05-14 2014-08-12 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
US9700570B2 (en) 2014-05-27 2017-07-11 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9789128B2 (en) 2012-05-14 2017-10-17 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10350227B2 (en) 2012-05-14 2019-07-16 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
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US9655908B2 (en) 2012-05-14 2017-05-23 Antecip Bioventures Ii Llc Neridronic acid molecular complex for treating complex regional pain syndrome
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US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US10463682B2 (en) 2012-05-14 2019-11-05 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
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US20150051175A1 (en) * 2012-05-14 2015-02-19 Antecip Bioventures Ii Llc Co-Administration of Steroids and Zoledronic Acid to Prevent and Treat Pain
US9827256B2 (en) 2014-05-27 2017-11-28 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating lower back pain
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US10039773B2 (en) 2012-05-14 2018-08-07 Antecip Bioventures Ii Llc Neridronic acid for treating arthritis
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US9844559B2 (en) 2012-05-14 2017-12-19 Antecip Bioventures Ii Llc Neridronic acid for treating bone marrow lesions
US9707245B2 (en) 2012-05-14 2017-07-18 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
US10080765B2 (en) 2012-05-14 2018-09-25 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
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CN102688206B (zh) * 2012-05-29 2014-08-20 石药集团中奇制药技术（石家庄）有限公司 一种匹伐他汀钙片及其制备方法
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JP2020536100A (ja) 2017-10-04 2020-12-10 セルジーン コーポレイション シス−４−［２−｛［（３ｓ，４ｒ）−３−フルオロキサン−４−イル］アミノ｝−８−（２，４，６−トリクロロアニリノ）−９ｈ−プリン−９−イル］−１−メチルシクロヘキサン−１−カルボキサミドの製造プロセス
KR20200062270A (ko) 2017-10-04 2020-06-03 셀진 코포레이션 시스-4-[2-｛[(3s,4r)-3-플루오로옥산-4-일]아미노｝-8-(2,4,6-트리클로로아닐리노)-9h-퓨린-9-일]-1-메틸시클로헥산-1-카르복스아미드의 조성물 및 이용 방법
CN110787140A (zh) * 2018-08-01 2020-02-14 北京万全德众医药生物技术有限公司 比拉斯汀片剂及其制备方法

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Publication number Publication date
KR20010024184A (ko) 2001-03-26
JP2001517616A (ja) 2001-10-09
DE1027037T1 (de) 2002-11-28
CN1270516A (zh) 2000-10-18
BR9812480A (pt) 2000-09-26
EP1027037A1 (en) 2000-08-16
JP3589977B2 (ja) 2004-11-17
FI109088B (fi) 2002-05-31
WO1999015155A1 (en) 1999-04-01
HK1031325A1 (en) 2001-06-15
SK3932000A3 (en) 2000-11-07
EE200000096A (et) 2000-12-15
CZ298675B6 (cs) 2007-12-19
CZ2000787A3 (cs) 2000-08-16
EE04218B1 (et) 2004-02-16
EP1027037B1 (en) 2003-12-03
UA73078C2 (uk) 2005-06-15
DE69820287T2 (de) 2004-10-14
HUP0004383A3 (en) 2006-06-28
FI973733A (fi) 1999-03-20
EA002331B1 (ru) 2002-04-25
CN1124130C (zh) 2003-10-15
HUP0004383A2 (hu) 2001-08-28
CA2301185A1 (en) 1999-04-01
HRP20000142A2 (en) 2000-06-30
HRP20000142B1 (en) 2004-06-30
IS5404A (is) 2000-03-14
ES2212341T3 (es) 2004-07-16
DE29824938U1 (de) 2003-07-31
BG64886B1 (bg) 2006-08-31
SK284088B6 (sk) 2004-09-08
BG104265A (en) 2000-11-30
CA2301185C (en) 2006-11-28
NO20001417D0 (no) 2000-03-17
ATE255410T1 (de) 2003-12-15
SI1027037T1 (en) 2004-04-30
NO20001417L (no) 2000-05-19
ID24423A (id) 2000-07-20
PT1027037E (pt) 2004-04-30
IL135130A (en) 2004-09-27
HU226118B1 (en) 2008-04-28
AU737738B2 (en) 2001-08-30
EA200000317A1 (ru) 2000-10-30
IL135130A0 (en) 2001-05-20
PL191166B1 (pl) 2006-03-31
TR200000722T2 (tr) 2000-11-21
AU9268598A (en) 1999-04-12
FI973733A0 (fi) 1997-09-19
NZ503766A (en) 2002-02-01
NO327728B1 (no) 2009-09-14
DE69820287D1 (de) 2004-01-15
PL339290A1 (en) 2000-12-04

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