HN2004000285A - ANTICUERPOS DIRIGIDOS A c-MET - Google Patents

ANTICUERPOS DIRIGIDOS A c-MET

Info

Publication number
HN2004000285A
HN2004000285A HN2004000285A HN2004000285A HN2004000285A HN 2004000285 A HN2004000285 A HN 2004000285A HN 2004000285 A HN2004000285 A HN 2004000285A HN 2004000285 A HN2004000285 A HN 2004000285A HN 2004000285 A HN2004000285 A HN 2004000285A
Authority
HN
Honduras
Prior art keywords
antibodies
met
refers
human
present
Prior art date
Application number
HN2004000285A
Other languages
English (en)
Inventor
R Michaud Neil
Kajiji Shama
Borzillo Gary
Bedian Vahe
Coleman Kevin
L Green Larry
Jia Xiao-Chi
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HN2004000285A publication Critical patent/HN2004000285A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

LA PRESENTE INVENCION SE REFIERE A ANTICUERPOS QUE INCLUYEN ANTICUERPOS QUE LIGAN ANTIGENO DE LOS MISMOS QUE SE LIGAN ESPECIFICAMENTE A c-MET, PREFERENTEMENTE A c-MET HUMANO Y QUE FUNCIONAN PARA INHIBIR C-MET. LA INVENCION SE REFIERE TAMBIEN A ANTICUERPOS QUE SON QUIMERICO, BIESPECIFICOS, DERIVATIZADOS, ANTICUERPOS DE CADENA SIMPLE O PORCIONES DE PROTEINAS DE FUSION. LA INVENCION TAMBIEN SE REFIERE A INMUNOGLOBULINAS AISLADAS DE CADENA PESADA Y LIVIANA DERIVADAS DE ANTICUERPOS ANTI c-MET HUMANOS Y A MOLECULAS DE ACIDO NUCLEICO QUE CODIFICAN TALES INMUNOGLOBINAS. LA PRESENTE INVENCION TAMBIEN SE REFIERE A METODOS PARA FABRICAR ANTICUERPOS ANTI-C-MET HUMANOS, COMPOSICIONES QUE COMPRENDEN ESTOS ANTICUERPOS Y A METODOS PARA USAR LOS ANTICUERPOS Y COMPOSICIONES PARA DIAGNOSTICO Y TRATAMIENTO LA INVENCION TAMBIEN SE PROVEE METODOS DE TERAPIA CON GENES QUE USAN MOLECULAS DE ACIDO NUCLEICO QUE CODIFICAN LAS MOLECULAS DE INMUNOGLOBULINA Y/O LIVIANA QUE COMPRENDEN LOS ANTICUERPOS ANTI-c-MET HUMANOS. LA INVENCION TAMBIEN SE REFIERE A ANIMALES O PLANTAS TRANSGENICOS QUE COMPRENDEN MOLECULAS DE ACIDO NUCLEICO DE LA PRESENTE INVENCION.
HN2004000285A 2003-08-04 2004-08-02 ANTICUERPOS DIRIGIDOS A c-MET HN2004000285A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49243203P 2003-08-04 2003-08-04

Publications (1)

Publication Number Publication Date
HN2004000285A true HN2004000285A (es) 2006-04-27

Family

ID=32991033

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2004000285A HN2004000285A (es) 2003-08-04 2004-08-02 ANTICUERPOS DIRIGIDOS A c-MET

Country Status (15)

Country Link
US (4) US7498420B2 (es)
EP (1) EP1660127A4 (es)
JP (1) JP2007501013A (es)
AR (1) AR047717A1 (es)
BR (1) BRPI0413272A (es)
CA (1) CA2534563A1 (es)
GB (1) GB2404660A (es)
GT (1) GT200400149A (es)
HN (1) HN2004000285A (es)
NL (1) NL1026776C2 (es)
PA (1) PA8608401A1 (es)
PE (1) PE20050727A1 (es)
TW (1) TW200523269A (es)
UY (1) UY28453A1 (es)
WO (1) WO2005016382A1 (es)

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