DK666289A - Arensulfonamidderivater - Google Patents
Arensulfonamidderivater Download PDFInfo
- Publication number
- DK666289A DK666289A DK666289A DK666289A DK666289A DK 666289 A DK666289 A DK 666289A DK 666289 A DK666289 A DK 666289A DK 666289 A DK666289 A DK 666289A DK 666289 A DK666289 A DK 666289A
- Authority
- DK
- Denmark
- Prior art keywords
- dividues
- arensulphonide
- arensulphonide dividues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/10—Quaternary compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32591088 | 1988-12-26 | ||
| JP32591088 | 1988-12-26 | ||
| JP7641989 | 1989-03-30 | ||
| JP7641989 | 1989-03-30 | ||
| JP8786889 | 1989-04-10 | ||
| JP8786889 | 1989-04-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK666289D0 DK666289D0 (da) | 1989-12-22 |
| DK666289A true DK666289A (da) | 1990-06-27 |
| DK175678B1 DK175678B1 (da) | 2005-01-17 |
Family
ID=27302151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198906662A DK175678B1 (da) | 1988-12-26 | 1989-12-22 | Forbindelser med afslappende aktivitet på glatte muskler i kar |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5081246A (da) |
| KR (1) | KR0183374B1 (da) |
| AT (1) | AT398201B (da) |
| CA (1) | CA2005741C (da) |
| CH (1) | CH680441A5 (da) |
| DK (1) | DK175678B1 (da) |
| ES (1) | ES2029759A6 (da) |
| FR (1) | FR2640973B1 (da) |
| GB (1) | GB2228933B (da) |
| NL (1) | NL193726C (da) |
| SE (1) | SE503081C2 (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340811A (en) * | 1990-03-08 | 1994-08-23 | Asahi Kasei Kogyo Kabushiki Kaisha | Isoquinoline-or quinoline-sulfonamide derivative and a pharmaceutical composition comprising the same |
| JPH069402A (ja) * | 1991-05-15 | 1994-01-18 | Hiroyoshi Hidaka | 抗潰瘍剤 |
| FR2679906B1 (fr) * | 1991-07-31 | 1995-01-20 | Adir | Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| DE69116576T2 (de) * | 1991-09-05 | 1996-10-10 | Pharno Wedropharm Gmbh | Aromatische sulfonamidderivate, ihre verwendung als enzyminhibitoren und diese verbindungen enthaltende pharmazeutische zusammensetzungen |
| US5378715A (en) * | 1992-02-24 | 1995-01-03 | Bristol-Myers Squibb Co. | Sulfonamide endothelin antagonists |
| US5514696A (en) * | 1992-05-06 | 1996-05-07 | Bristol-Myers Squibb Co. | Phenyl sulfonamide endothelin antagonists |
| US5420123A (en) * | 1992-12-21 | 1995-05-30 | Bristol-Myers Squibb Company | Dibenzodiazepine endothelin antagonists |
| US5965732A (en) * | 1993-08-30 | 1999-10-12 | Bristol-Myers Squibb Co. | Sulfonamide endothelin antagonists |
| US5612359A (en) * | 1994-08-26 | 1997-03-18 | Bristol-Myers Squibb Company | Substituted biphenyl isoxazole sulfonamides |
| US5780473A (en) * | 1995-02-06 | 1998-07-14 | Bristol-Myers Squibb Company | Substituted biphenyl sulfonamide endothelin antagonists |
| US5760038A (en) * | 1995-02-06 | 1998-06-02 | Bristol-Myers Squibb Company | Substituted biphenyl sulfonamide endothelin antagonists |
| US5846990A (en) * | 1995-07-24 | 1998-12-08 | Bristol-Myers Squibb Co. | Substituted biphenyl isoxazole sulfonamides |
| JPH09124620A (ja) | 1995-10-11 | 1997-05-13 | Bristol Myers Squibb Co | 置換ビフェニルスルホンアミドエンドセリン拮抗剤 |
| CZ263098A3 (cs) | 1996-02-20 | 1999-05-12 | Bristol-Myers Squibb Company | Způsoby přípravy bifenylisoxazolsulfonamidů |
| US5856507A (en) * | 1997-01-21 | 1999-01-05 | Bristol-Myers Squibb Co. | Methods for the preparation of biphenyl isoxazole sulfonamides |
| US5939446A (en) * | 1996-04-09 | 1999-08-17 | Bristol-Myers Squibb Co. | Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists |
| TW536540B (en) * | 1997-01-30 | 2003-06-11 | Bristol Myers Squibb Co | Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe |
| WO1998033781A1 (en) * | 1997-01-30 | 1998-08-06 | Bristol-Myers Squibb Company | Method for preventing or treating low renin hypertension by administering an endothelin antagonist |
| US6339087B1 (en) | 1997-08-18 | 2002-01-15 | Syntex (U.S.A.) Llc | Cyclic amine derivatives-CCR-3 receptor antagonists |
| IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
| EP1131290B1 (en) | 1998-11-20 | 2008-02-20 | F. Hoffmann-La Roche Ag | Piperidine ccr-3 receptor antagonists |
| EP1165472A4 (en) | 1999-03-19 | 2002-11-20 | Bristol Myers Squibb Co | METHOD FOR PRODUCING BIPHENYL ISOXAZOLE |
| US6337326B1 (en) | 1999-11-08 | 2002-01-08 | American Home Products Corporation | N-aryl-(homopiperazinyl)-cyclohexyl amines |
| US6639082B2 (en) | 2000-10-17 | 2003-10-28 | Bristol-Myers Squibb Company | Methods for the preparation of biphenyl isoxazole sulfonamides |
| US7094895B2 (en) * | 2001-12-21 | 2006-08-22 | King Pharmaceuticals Research & Development, Inc. | Tyrosyl derivatives and their use as P2X7 receptor modulators |
| KR101149954B1 (ko) * | 2005-08-30 | 2012-06-01 | 아사히 가세이 파마 가부시키가이샤 | 술폰아미드 화합물 |
| GB0617222D0 (en) * | 2006-08-31 | 2006-10-11 | Vereniging Het Nl Kanker I | Antibiotics |
| US8415372B2 (en) * | 2007-02-27 | 2013-04-09 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| AU2008220104B2 (en) * | 2007-02-28 | 2012-09-27 | Asahi Kasei Pharma Corporation | Sulfonamide derivative |
| JP5234825B2 (ja) | 2007-07-02 | 2013-07-10 | 旭化成ファーマ株式会社 | スルホンアミド化合物及びその結晶 |
| CN104220421A (zh) | 2012-03-20 | 2014-12-17 | 阿达梅德公司 | 用于治疗中枢神经***疾病的苄胺的磺酰胺衍生物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS609495B2 (ja) * | 1976-02-18 | 1985-03-11 | 萬有製薬株式会社 | ω−（アリ−ルスルホンアミド）−アルキルアミン |
| DD142804A3 (de) * | 1977-11-07 | 1980-07-16 | Wagner Guenter | Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden |
| US4456757A (en) * | 1981-03-20 | 1984-06-26 | Asahi Kasei Kogyo Kabushiki Kaisha | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
| SE8203887D0 (sv) * | 1982-06-23 | 1982-06-23 | Kabivitrum Ab | Nya trombininhiberande foreningar |
| JPS5993054A (ja) * | 1982-11-18 | 1984-05-29 | Asahi Chem Ind Co Ltd | イソキノリンスルホン酸アミド誘導体 |
| JPS6081168A (ja) * | 1983-10-13 | 1985-05-09 | Asahi Chem Ind Co Ltd | アミジン誘導体 |
| US4678783B1 (en) * | 1983-11-04 | 1995-04-04 | Asahi Chemical Ind | Substituted isoquinolinesulfonyl compounds |
| JPS61126026A (ja) * | 1984-11-26 | 1986-06-13 | Hiroyoshi Hidaka | イソキノリンスルホン酸アミドを有効成分とする抗癌剤 |
| DE3583287D1 (de) * | 1984-12-27 | 1991-07-25 | Asahi Chemical Ind | Substituierte isochinolinsulfonyl-verbindungen. |
| JPS61271221A (ja) * | 1985-05-28 | 1986-12-01 | Hiroyoshi Hidaka | ５−イソキノリンスルホニルピペラジンを有効成分とする抗癌剤 |
| JPS61293914A (ja) * | 1985-06-24 | 1986-12-24 | Hiroyoshi Hidaka | イソキノリン誘導体を有効成分とする抗癌剤 |
| JPH062741B2 (ja) * | 1985-10-29 | 1994-01-12 | 旭化成工業株式会社 | ２級のイソキノリンスルホンアミド誘導体 |
| JPH0667926B2 (ja) * | 1985-11-12 | 1994-08-31 | 旭化成工業株式会社 | 環状のイソキノリンスルホンアミド誘導体 |
| JPS6322757A (ja) * | 1986-03-05 | 1988-01-30 | Tokyo Tatsuno Co Ltd | 自動車用サ−ビス装置 |
| JPH0676384B2 (ja) * | 1986-06-20 | 1994-09-28 | 旭化成工業株式会社 | １−クロル−５−イソキノリンスルホン酸 |
| JPH07603B2 (ja) * | 1987-02-27 | 1995-01-11 | 北陸製薬株式会社 | イソキノリンスルホンアミド誘導体 |
-
1989
- 1989-12-15 CA CA002005741A patent/CA2005741C/en not_active Expired - Lifetime
- 1989-12-19 SE SE8904261A patent/SE503081C2/sv not_active IP Right Cessation
- 1989-12-20 US US07/453,623 patent/US5081246A/en not_active Expired - Lifetime
- 1989-12-21 GB GB8928895A patent/GB2228933B/en not_active Expired - Fee Related
- 1989-12-21 CH CH4647/89A patent/CH680441A5/de not_active IP Right Cessation
- 1989-12-22 DK DK198906662A patent/DK175678B1/da not_active IP Right Cessation
- 1989-12-22 AT AT0293589A patent/AT398201B/de not_active IP Right Cessation
- 1989-12-22 ES ES8904335A patent/ES2029759A6/es not_active Expired - Fee Related
- 1989-12-22 FR FR898917091A patent/FR2640973B1/fr not_active Expired - Fee Related
- 1989-12-22 NL NL8903143A patent/NL193726C/nl not_active IP Right Cessation
- 1989-12-26 KR KR1019890019533A patent/KR0183374B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL193726B (nl) | 2000-04-03 |
| ATA293589A (de) | 1994-02-15 |
| SE503081C2 (sv) | 1996-03-18 |
| KR900009598A (ko) | 1990-07-05 |
| AT398201B (de) | 1994-10-25 |
| DK175678B1 (da) | 2005-01-17 |
| SE8904261D0 (sv) | 1989-12-19 |
| US5081246A (en) | 1992-01-14 |
| GB8928895D0 (en) | 1990-02-28 |
| CA2005741C (en) | 1998-06-02 |
| GB2228933A (en) | 1990-09-12 |
| SE8904261L (sv) | 1990-06-27 |
| CA2005741A1 (en) | 1990-06-26 |
| DK666289D0 (da) | 1989-12-22 |
| FR2640973B1 (da) | 1992-03-27 |
| NL193726C (nl) | 2000-08-04 |
| CH680441A5 (da) | 1992-08-31 |
| NL8903143A (nl) | 1990-07-16 |
| ES2029759A6 (es) | 1992-09-01 |
| GB2228933B (en) | 1993-03-31 |
| KR0183374B1 (ko) | 1999-05-01 |
| FR2640973A1 (da) | 1990-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |
Country of ref document: DK |