DK205789A - Optisk aktive pyridoncarboxylsyrederivater og laegemidler indeholdende disse - Google Patents

Optisk aktive pyridoncarboxylsyrederivater og laegemidler indeholdende disse Download PDF

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Publication number
DK205789A
DK205789A DK205789A DK205789A DK205789A DK 205789 A DK205789 A DK 205789A DK 205789 A DK205789 A DK 205789A DK 205789 A DK205789 A DK 205789A DK 205789 A DK205789 A DK 205789A
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DK
Denmark
Prior art keywords
acid derivatives
pyridon
carboxylic acid
medicines containing
optic active
Prior art date
Application number
DK205789A
Other languages
English (en)
Other versions
DK205789D0 (da
DK175467B1 (da
Inventor
Isao Hayakawa
Youichi Kimura
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of DK205789D0 publication Critical patent/DK205789D0/da
Publication of DK205789A publication Critical patent/DK205789A/da
Application granted granted Critical
Publication of DK175467B1 publication Critical patent/DK175467B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK205789A 1988-04-27 1989-04-27 Optisk aktive pyridoncarboxylsyrederivater DK175467B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10462588 1988-04-27
JP10462588 1988-04-27
JP29698488 1988-11-24
JP29698488 1988-11-24

Publications (3)

Publication Number Publication Date
DK205789D0 DK205789D0 (da) 1989-04-27
DK205789A true DK205789A (da) 1989-10-28
DK175467B1 DK175467B1 (da) 2004-11-01

Family

ID=26445063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK205789A DK175467B1 (da) 1988-04-27 1989-04-27 Optisk aktive pyridoncarboxylsyrederivater

Country Status (26)

Country Link
US (4) US5587386A (da)
EP (1) EP0341493B1 (da)
JP (5) JP2714597B2 (da)
KR (1) KR0184614B1 (da)
CN (1) CN1033751C (da)
AT (1) ATE182145T1 (da)
AU (1) AU625414B2 (da)
BG (1) BG61122B2 (da)
CA (1) CA1340801C (da)
DE (1) DE68929030T2 (da)
DK (1) DK175467B1 (da)
ES (1) ES2135372T3 (da)
FI (1) FI96947C (da)
GR (1) GR3031365T3 (da)
HK (1) HK1002108A1 (da)
HU (1) HU211136A9 (da)
IL (1) IL90062A (da)
LV (1) LV10092B (da)
MY (1) MY105136A (da)
NO (1) NO175939C (da)
NZ (1) NZ228893A (da)
PT (1) PT90377B (da)
RU (1) RU2075475C1 (da)
SG (1) SG48036A1 (da)
UA (1) UA29378C2 (da)
YU (1) YU48432B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
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IL90062A (en) 1988-04-27 1994-10-07 Daiichi Seiyaku Co History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
CN1054980A (zh) * 1990-02-19 1991-10-02 杏林制药株式会社 具有旋光活性的8-甲氧基喹诺酮羧酸衍生物，它们的制备方法以及它们的中间体
MY109714A (en) * 1990-10-18 1997-04-30 Daiichi Seiyaku Co Process for preparing 8-chloroquinolone derivatives
AU661999B2 (en) * 1991-05-28 1995-08-17 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative
DK0641339T3 (da) * 1991-06-19 1999-12-20 Pfizer Antibakterielle midler med azaspiroquinolon
KR960011370B1 (ko) * 1991-12-31 1996-08-22 재단법인 한국화학연구소 스피로알킬아민 유도체와 그의 제조방법
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
EP0773214A4 (en) * 1994-07-18 1998-04-15 Ube Industries TRIFLUORMETHYLQUINOLINE CARBONIC ACID DERIVATIVES
DE69627985T2 (de) * 1995-02-02 2004-02-19 Daiichi Pharmaceutical Co., Ltd. Heterozyklische verbindungen
DE69628158T2 (de) * 1995-02-07 2004-03-25 Daiichi Pharmaceutical Co., Ltd. Heterocyclische spiroderivate
JPH09124556A (ja) 1995-08-30 1997-05-13 Dai Ichi Seiyaku Co Ltd ハロゲン化シクロプロパン誘導体の製造方法
US6121285A (en) 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
ATE317393T1 (de) * 1995-11-22 2006-02-15 Daiichi Seiyaku Co Substituierte aminocycloalkylpyrrolidinderivate
PT882725E (pt) * 1996-02-09 2003-04-30 Toyama Chemical Co Ltd Derivados do acido quinolonacarboxilico ou os seus sais
TW425394B (en) * 1996-04-24 2001-03-11 Daiichi Seiyaku Co Antimicrobial quinolone derivatives having 3-(N-cycloalkyl) aminomethylpyrrolidine group
AU1040597A (en) * 1996-12-04 1998-06-29 Daiichi Pharmaceutical Co., Ltd. Substituted aminomethylpyrrolidine derivatives
PT1134219E (pt) * 1998-11-24 2005-09-30 Daiichi Seiyaku Co Derivados de aminometilpirrolidina cicloalquil-substituidos
EP1182202B1 (en) * 1999-03-10 2004-06-02 Daiichi Pharmaceutical Co., Ltd. Aminomethylpyrrolidine derivatives having aromatic substituents
KR100768034B1 (ko) 1999-03-17 2007-10-17 다이이찌 세이야꾸 가부시기가이샤 의약 조성물
KR100817425B1 (ko) * 2000-02-09 2008-03-27 다이이찌 세이야꾸 가부시기가이샤 피리돈카복실산류를 유효성분으로 하는 항항산균제
RU2002135315A (ru) * 2000-03-31 2004-05-27 Дайити Фармасьютикал Ко.,Лтд. (Jp) Производные хинолонкарбоновой кислоты
ES2305065T3 (es) * 2000-04-24 2008-11-01 Daiichi Sankyo Company, Limited Preparacion liquida estable que contiene sitafloxacina.
CA2417764C (en) 2000-08-08 2009-05-05 Katsuo Kataoka Highly absorbable solid preparations containing sitafloxacin and tartaric acid
RU2004136997A (ru) * 2002-05-17 2005-06-27 Дайити Фармасьютикал Ко., Лтд. (JP) Способ получения производных хинолонкарбоновой кислоты
ATE488489T1 (de) * 2003-01-07 2010-12-15 Daiichi Sankyo Co Ltd Verfahren zur reduktiven deshalogenierung
US7085154B2 (en) * 2003-06-03 2006-08-01 Samsung Electronics Co., Ltd. Device and method for pulse width control in a phase change memory device
JP4820290B2 (ja) * 2004-05-13 2011-11-24 第一三共株式会社 置換ピロリジン誘導体
JP5063032B2 (ja) * 2005-05-19 2012-10-31 第一三共株式会社 トリ−、テトラ−置換−３−アミノピロリジン誘導体
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7928232B2 (en) 2005-05-20 2011-04-19 Daiichi Sankyo Company, Limited Method for producing asymmetric tetrasubstituted carbon atom-containing compound
US7977346B2 (en) 2006-01-17 2011-07-12 Guoqing Paul Chen Spiro compounds and methods of use
TWI386401B (zh) * 2006-03-27 2013-02-21 Daiichi Seiyaku Co 醫藥用水合物
MY162052A (en) 2007-01-05 2017-05-31 Daiichi Sankyo Co Ltd Fused substitute aminopyrrolidine derivative
CN102089439B (zh) 2008-07-11 2013-11-13 住友化学株式会社 (1s，2r)-2-氯-2-氟环丙烷羧酸的制造方法
FR2961207B1 (fr) * 2010-06-09 2013-01-18 Oreal Utilisation d'un derive de 4- carboxy 2-pyrrolidinone comme solvant dans les compositions cosmetiques ; compositions cosmetiques les contenant ; nouveaux composes
CN103467448B (zh) * 2013-09-18 2015-04-15 浙江司太立制药股份有限公司 7-(3-氨基-4-烷氧亚胺基-1-哌啶基)-1-[(1r,2s)-2-氟环丙基]喹诺酮羧酸类化合物及其制备方法
EP2957561A1 (en) * 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections
CN105330590B (zh) * 2015-10-15 2018-09-25 广州市朗启医药科技有限责任公司 西他沙星五元环侧链中间体的制备方法
CN109912504B (zh) * 2019-04-04 2020-11-10 山东省联合农药工业有限公司 一种喹啉羧酸类化合物及其制备方法与用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6212760A (ja) * 1984-12-14 1987-01-21 Dai Ichi Seiyaku Co Ltd １−（２−ハロゲノシクロプロピル）キノリンカルボン酸誘導体
AU5427286A (en) * 1985-03-08 1986-09-11 Kyorin Pharmaceutical Co. Ltd. 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives
DE3509546A1 (de) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
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US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US4735949A (en) 1986-02-18 1988-04-05 Warner-Lambert Company Disubstituted-7-pyrrolidinonaphthyridine antibacterial agents
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
DE3702393A1 (de) * 1987-01-28 1988-08-11 Bayer Ag 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
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IL90062A (en) * 1988-04-27 1994-10-07 Daiichi Seiyaku Co History of pyridonecarboxylic acid, their preparation and pharmaceutical preparations containing them
AU618823B2 (en) * 1988-07-20 1992-01-09 Sankyo Company Limited 4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use
US5286723A (en) 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
FI901201A0 (fi) * 1989-03-13 1990-03-09 Bristol Myers Squibb Co Antibakteriella 5-substituerade 1,4-dihydro-4-oxonaftyridin-3-karboxylatderivat och deras framstaellning.
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
RU2002135315A (ru) 2000-03-31 2004-05-27 Дайити Фармасьютикал Ко.,Лтд. (Jp) Производные хинолонкарбоновой кислоты
JP4820290B2 (ja) * 2004-05-13 2011-11-24 第一三共株式会社 置換ピロリジン誘導体

Also Published As

Publication number Publication date
JP2917010B2 (ja) 1999-07-12
NO891698D0 (no) 1989-04-25
US5587386A (en) 1996-12-24
JPH07300416A (ja) 1995-11-14
BG61122B2 (bg) 1996-11-29
PT90377B (pt) 1994-09-30
KR900016205A (ko) 1990-11-12
FI96947C (fi) 1996-09-25
EP0341493B1 (en) 1999-07-14
SG48036A1 (en) 1998-04-17
DK205789D0 (da) 1989-04-27
JPH11124367A (ja) 1999-05-11
GR3031365T3 (en) 2000-01-31
USRE41149E1 (en) 2010-02-23
US6031102A (en) 2000-02-29
IL90062A0 (en) 1989-12-15
CN1033751C (zh) 1997-01-08
JP2903292B2 (ja) 1999-06-07
ATE182145T1 (de) 1999-07-15
EP0341493A3 (en) 1990-12-19
FI891980A0 (fi) 1989-04-26
FI891980A (fi) 1989-10-28
NZ228893A (en) 1990-06-26
UA29378C2 (uk) 2000-11-15
JPH1067779A (ja) 1998-03-10
PT90377A (pt) 1989-11-10
CA1340801C (en) 1999-10-26
FI96947B (fi) 1996-06-14
MY105136A (en) 1994-08-30
JP2714597B2 (ja) 1998-02-16
DK175467B1 (da) 2004-11-01
RU2075475C1 (ru) 1997-03-20
NO891698L (no) 1989-10-30
JPH02231475A (ja) 1990-09-13
ES2135372T3 (es) 1999-11-01
JPH11124380A (ja) 1999-05-11
YU87589A (en) 1990-12-31
NO175939B (no) 1994-09-26
DE68929030T2 (de) 2000-03-23
CN1037507A (zh) 1989-11-29
LV10092B (en) 1995-02-20
DE68929030D1 (de) 1999-08-19
EP0341493A2 (en) 1989-11-15
HK1002108A1 (en) 1998-07-31
AU625414B2 (en) 1992-07-09
KR0184614B1 (ko) 1999-05-01
AU3370289A (en) 1989-11-02
NO175939C (no) 1995-01-04
IL90062A (en) 1994-10-07
HU211136A9 (en) 1995-10-30
YU48432B (sh) 1998-07-10
US5767127A (en) 1998-06-16

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