DK1695703T3 - Nye anvendelser for aminosyrekrampestillende midler - Google Patents

Nye anvendelser for aminosyrekrampestillende midler

Info

Publication number
DK1695703T3
DK1695703T3 DK06012400.5T DK06012400T DK1695703T3 DK 1695703 T3 DK1695703 T3 DK 1695703T3 DK 06012400 T DK06012400 T DK 06012400T DK 1695703 T3 DK1695703 T3 DK 1695703T3
Authority
DK
Denmark
Prior art keywords
lower alkyl
aryl
heterocyclic
unsubstituted
substituted
Prior art date
Application number
DK06012400.5T
Other languages
English (en)
Inventor
Robert H Harris
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of DK1695703T3 publication Critical patent/DK1695703T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK06012400.5T 2000-08-25 2001-08-24 Nye anvendelser for aminosyrekrampestillende midler DK1695703T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22823000P 2000-08-25 2000-08-25
EP01966230A EP1365787B1 (en) 2000-08-25 2001-08-24 Use of amino acid anticonvulsants for treatment of pain

Publications (1)

Publication Number Publication Date
DK1695703T3 true DK1695703T3 (da) 2010-10-25

Family

ID=22856332

Family Applications (4)

Application Number Title Priority Date Filing Date
DK01966230T DK1365787T3 (da) 2000-08-25 2001-08-24 Anvendelse af aminosyre-holdige, krampestillende midler til behandling af smerte
DK04021728T DK1486206T3 (da) 2000-08-25 2001-08-24 Anvendelse af antikonvulsiv aminosyre til behandling af bipolære sygdomme
DK04021727T DK1486205T3 (da) 2000-08-25 2001-08-24 Anvendelse af antikonvulsive aminosyrer til behandling af migræne
DK06012400.5T DK1695703T3 (da) 2000-08-25 2001-08-24 Nye anvendelser for aminosyrekrampestillende midler

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK01966230T DK1365787T3 (da) 2000-08-25 2001-08-24 Anvendelse af aminosyre-holdige, krampestillende midler til behandling af smerte
DK04021728T DK1486206T3 (da) 2000-08-25 2001-08-24 Anvendelse af antikonvulsiv aminosyre til behandling af bipolære sygdomme
DK04021727T DK1486205T3 (da) 2000-08-25 2001-08-24 Anvendelse af antikonvulsive aminosyrer til behandling af migræne

Country Status (13)

Country Link
US (6) US6884910B2 (da)
EP (5) EP2210598B1 (da)
JP (2) JP4307068B2 (da)
AT (4) ATE375793T1 (da)
AU (6) AU2001286763C1 (da)
CA (2) CA2419285C (da)
CY (5) CY1107668T1 (da)
DE (4) DE60127459T2 (da)
DK (4) DK1365787T3 (da)
ES (5) ES2348646T3 (da)
LU (1) LU91512I2 (da)
PT (4) PT1695703E (da)
WO (1) WO2002015922A2 (da)

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AU2001286763C1 (en) 2000-08-25 2006-03-02 Research Corporation Technologies, Inc. New uses for amino acid anticonvulsants for treatment of pain
DK1243262T3 (da) * 2001-03-20 2006-10-02 Sanol Arznei Schwarz Gmbh Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter
EP1243263B1 (en) * 2001-03-21 2002-11-27 Schwarz Pharma Ag Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain
US20040087642A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
US20050233472A1 (en) * 2003-09-19 2005-10-20 Kao H P Spotting high density plate using a banded format
EP1689378B1 (en) * 2003-12-02 2009-04-15 Schwarz Pharma Ag Novel use of peptide compounds for treating central neuropathic pain
EP1537862A1 (en) * 2003-12-02 2005-06-08 Schwarz Pharma Ag Novel use of peptide compounds for treating central neuropathic pain
EP1579858A1 (en) * 2004-03-26 2005-09-28 Schwarz Pharma Ag Novel use of peptide compounds for treating pain in painful diabetic neuropathy
KR20070007931A (ko) * 2004-04-16 2007-01-16 쉬바르츠파르마에이지 만성 두통의 예방 및 치료를 위한 펩티드 화합물의 용도
EP1604654A1 (en) * 2004-05-18 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating dyskinesia
EP1604655A1 (en) * 2004-06-09 2005-12-14 Schwarz Pharma Ag Novel use of peptide compounds for treating pain in trigeminal neuralgia
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EA014055B1 (ru) 2004-08-27 2010-08-30 Шварц Фарма Аг Применение пептидных соединений для лечения боли при раке кости, а также боли, вызванной химиотерапией и нуклеозидами
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US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
EP1754476A1 (en) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia
TWI397417B (zh) 2006-06-15 2013-06-01 Ucb Pharma Gmbh 具有協同抗驚厥功效之醫藥組成物
EP1920780A1 (en) * 2006-10-12 2008-05-14 Schwarz Pharma Ag Peptide compounds for the treatment of hyperexcitability disorders
CN101466390B (zh) * 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
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Also Published As

Publication number Publication date
US7186859B2 (en) 2007-03-06
ATE375792T1 (de) 2007-11-15
ES2348646T3 (es) 2010-12-10
AU2009202363A1 (en) 2009-07-02
DE60127459D1 (de) 2007-05-03
CA2740815A1 (en) 2002-02-28
EP1486205B1 (en) 2007-10-17
US7148378B2 (en) 2006-12-12
US20130316953A1 (en) 2013-11-28
US8519183B2 (en) 2013-08-27
CA2740815C (en) 2014-03-18
ATE357227T1 (de) 2007-04-15
PT1695703E (pt) 2010-11-16
ES2435000T3 (es) 2013-12-18
DE60131033D1 (de) 2007-11-29
EP1365787A2 (en) 2003-12-03
ES2294415T3 (es) 2008-04-01
DE60131032D1 (de) 2007-11-29
LU91512I2 (fr) 2009-03-16
JP4307068B2 (ja) 2009-08-05
PT1486205E (pt) 2008-01-25
EP2210598B1 (en) 2013-09-18
US20020086828A1 (en) 2002-07-04
CA2419285C (en) 2011-08-02
AU2009202363B2 (en) 2011-02-17
DK1365787T3 (da) 2007-07-23
WO2002015922A2 (en) 2002-02-28
WO2002015922A3 (en) 2003-09-25
ATE375793T1 (de) 2007-11-15
DE60127459T2 (de) 2007-07-12
AU8676301A (en) 2002-03-04
CY2009002I1 (el) 2009-11-04
EP1365787B1 (en) 2007-03-21
CY1107668T1 (el) 2010-07-28
ATE476971T1 (de) 2010-08-15
CY1107852T1 (el) 2013-06-19
PT1365787E (pt) 2007-06-29
CY1112349T1 (el) 2015-12-09
EP1695703B1 (en) 2010-08-11
AU2001286763B2 (en) 2005-11-24
DK1486205T3 (da) 2008-02-18
AU2009202362A1 (en) 2009-07-02
CA2419285A1 (en) 2002-02-28
DK1486206T3 (da) 2008-02-11
AU2011202293B2 (en) 2013-01-10
EP2210598A2 (en) 2010-07-28
DE60131033T2 (de) 2008-07-17
US6884910B2 (en) 2005-04-26
US20040097416A1 (en) 2004-05-20
AU2007202336B9 (en) 2009-10-29
AU2011202293A1 (en) 2011-06-09
ES2294414T3 (es) 2008-04-01
CY1107853T1 (el) 2013-06-19
AU2007202336A1 (en) 2007-06-14
AU2001286763C1 (en) 2006-03-02
JP2004506692A (ja) 2004-03-04
CY2009002I2 (el) 2009-11-04
EP1486205A1 (en) 2004-12-15
EP1695703A3 (en) 2006-12-13
AU2007202336B2 (en) 2009-09-24
JP2009108090A (ja) 2009-05-21
US7772427B2 (en) 2010-08-10
EP1695703A2 (en) 2006-08-30
US20100273716A1 (en) 2010-10-28
PT1486206E (pt) 2008-01-25
US20040087508A1 (en) 2004-05-06
DE60131032T2 (de) 2008-08-14
EP2210598A3 (en) 2011-07-20
US20070142297A1 (en) 2007-06-21
ES2281439T3 (es) 2007-10-01
JP5190334B2 (ja) 2013-04-24
EP1486206A1 (en) 2004-12-15
AU2009202362B2 (en) 2011-01-27
DE60142806D1 (de) 2010-09-23
EP1486206B1 (en) 2007-10-17

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