DE60131032D1 - Verwendung von antikonvulsiven Aminosäure zur Behandlung von Migräne - Google Patents
Verwendung von antikonvulsiven Aminosäure zur Behandlung von MigräneInfo
- Publication number
- DE60131032D1 DE60131032D1 DE60131032T DE60131032T DE60131032D1 DE 60131032 D1 DE60131032 D1 DE 60131032D1 DE 60131032 T DE60131032 T DE 60131032T DE 60131032 T DE60131032 T DE 60131032T DE 60131032 D1 DE60131032 D1 DE 60131032D1
- Authority
- DE
- Germany
- Prior art keywords
- lower alkyl
- aryl
- heterocyclic
- unsubstituted
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22823000P | 2000-08-25 | 2000-08-25 | |
US228230P | 2000-08-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60131032D1 true DE60131032D1 (de) | 2007-11-29 |
DE60131032T2 DE60131032T2 (de) | 2008-08-14 |
Family
ID=22856332
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60142806T Expired - Lifetime DE60142806D1 (de) | 2000-08-25 | 2001-08-24 | Aminosäure enthaltende Antikonvulsiva zur Behandlung von Zwangsstörungen |
DE60131032T Expired - Lifetime DE60131032T2 (de) | 2000-08-25 | 2001-08-24 | Verwendung von antikonvulsiven Aminosäure zur Behandlung von Migräne |
DE60127459T Expired - Lifetime DE60127459T2 (de) | 2000-08-25 | 2001-08-24 | Verwendung von aminosäurehaltigen Antikonvulsiva zur Behandlung von Schmerz |
DE60131033T Expired - Lifetime DE60131033T2 (de) | 2000-08-25 | 2001-08-24 | Verwendungen von antikonvulsiven Aminosäure zur Behandlung bipolarer Erkrankungen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60142806T Expired - Lifetime DE60142806D1 (de) | 2000-08-25 | 2001-08-24 | Aminosäure enthaltende Antikonvulsiva zur Behandlung von Zwangsstörungen |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60127459T Expired - Lifetime DE60127459T2 (de) | 2000-08-25 | 2001-08-24 | Verwendung von aminosäurehaltigen Antikonvulsiva zur Behandlung von Schmerz |
DE60131033T Expired - Lifetime DE60131033T2 (de) | 2000-08-25 | 2001-08-24 | Verwendungen von antikonvulsiven Aminosäure zur Behandlung bipolarer Erkrankungen |
Country Status (13)
Country | Link |
---|---|
US (6) | US6884910B2 (de) |
EP (5) | EP1365787B1 (de) |
JP (2) | JP4307068B2 (de) |
AT (4) | ATE357227T1 (de) |
AU (6) | AU2001286763C1 (de) |
CA (2) | CA2740815C (de) |
CY (5) | CY1107668T1 (de) |
DE (4) | DE60142806D1 (de) |
DK (4) | DK1486206T3 (de) |
ES (5) | ES2281439T3 (de) |
LU (1) | LU91512I2 (de) |
PT (4) | PT1486205E (de) |
WO (1) | WO2002015922A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60142806D1 (de) * | 2000-08-25 | 2010-09-23 | Res Corp Technologies Inc | Aminosäure enthaltende Antikonvulsiva zur Behandlung von Zwangsstörungen |
EP1243262B1 (de) | 2001-03-20 | 2006-05-31 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen bei der Behandlung von nicht-neuropathischem Entzündungsschmerz |
EP1243263B1 (de) * | 2001-03-21 | 2002-11-27 | Schwarz Pharma Ag | Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen |
US20040087642A1 (en) * | 2002-10-24 | 2004-05-06 | Zeldis Jerome B. | Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain |
US20050233472A1 (en) * | 2003-09-19 | 2005-10-20 | Kao H P | Spotting high density plate using a banded format |
EP1537862A1 (de) * | 2003-12-02 | 2005-06-08 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von zentralen neuropathische-Schmerzen |
AU2004294714B2 (en) * | 2003-12-02 | 2009-12-10 | Ucb Pharma Gmbh | Novel use of peptide compounds for treating central neuropathic pain |
EP1579858A1 (de) * | 2004-03-26 | 2005-09-28 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von diabetishen Neuropathie |
MXPA06011937A (es) | 2004-04-16 | 2007-01-26 | Sanol Arznei Schwarz Gmbh | Uso de compuestos peptidicos para la profilaxis y el tratamiento de dolor de cabeza cronico. |
EP1604654A1 (de) * | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von Dyskynesien |
EP1604655A1 (de) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von Trigeminusneuralgie |
US7427601B2 (en) * | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
EP1629839A1 (de) * | 2004-08-27 | 2006-03-01 | Schwarz Pharma Ag | Verwendung von Peptidverbindungen zur Behandlung von Knochenkrebsschmerz sowie von Chemotherapie- oder Nukleosid-induziertem Schmerz |
BRPI0514721A (pt) | 2004-08-27 | 2008-06-24 | Sanol Arznei Schwarz Gmbh | uso de compostos de peptìdeos para tratar dor de cáncer ósseo, dor induzida por quimioterapia e nucleosìdeo |
US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
EP1754476A1 (de) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamid (SPM 927) zur Behandlung von Myalgien, z.B. Fibromyalgie |
CN101466390B (zh) | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
EP1920780A1 (de) * | 2006-10-12 | 2008-05-14 | Schwarz Pharma Ag | Peptidverbindungen zur Behandlung von Krankheiten mit erhöhter Erregbarkeit |
SI2462990T1 (sl) * | 2006-06-15 | 2014-04-30 | Ucb Pharma Gmbh | Farmacevtski sestavek, ki obsega lakozamid in levetiracetam, s sinergističnim antikonvulzivnim učinkom |
US7489198B1 (en) | 2007-04-26 | 2009-02-10 | Lockheed Martin Corporation | Linear regulating switch |
WO2011101863A2 (en) | 2010-02-19 | 2011-08-25 | Cadila Healthcare Limited | Extended release pharmaceutical compositions of lacosamide |
WO2015200322A1 (en) * | 2014-06-23 | 2015-12-30 | Northwestern University | Methods of treating or ameliorating migraine |
WO2017079169A1 (en) | 2015-11-03 | 2017-05-11 | Kimberly-Clark Worldwide, Inc. | Paper tissue with high bulk and low lint |
WO2019108172A1 (en) | 2017-11-29 | 2019-06-06 | Kimberly-Clark Worldwide, Inc. | Fibrous sheet with improved properties |
BR112021001335B1 (pt) | 2018-07-25 | 2024-03-05 | Kimberly-Clark Worldwide, Inc | Método para fazer um substrato absorvente não tecido tridimensional (3d) |
Family Cites Families (37)
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BE795788A (nl) * | 1972-02-22 | 1973-08-22 | Akzo Nv | Werkwijze ter bereiding van peptiden en peptide-derivaten en de toepassing hiervan |
US4533657A (en) * | 1981-07-24 | 1985-08-06 | Sterling Drug Inc. | Analgesic dipeptide amides and method of use and composition thereof |
US4510082A (en) * | 1983-03-07 | 1985-04-09 | Eli Lilly And Company | Pharmacologically active peptides |
FR2546517B1 (fr) * | 1983-05-24 | 1987-04-24 | Panmedica | Nouveaux dipeptides du -l-5-hydroxy-tryptophane, procedes pour leur preparation et medicaments les contenant |
JPH0680079B2 (ja) * | 1984-11-09 | 1994-10-12 | エーザイ株式会社 | ポリペプチド |
US5654301A (en) * | 1985-02-15 | 1997-08-05 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
US5378729A (en) * | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
US5728680A (en) * | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
US5331089A (en) * | 1988-03-25 | 1994-07-19 | Merck Sharpe & Dohme, Ltd. | Peptides useful as tachykinin agonists |
US5178729A (en) * | 1991-01-15 | 1993-01-12 | James River Corporation Of Virginia | High purity stratified tissue and method of making same |
US5854217A (en) * | 1992-09-28 | 1998-12-29 | Bearsden Bio, Inc. | Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function |
AU5890394A (en) | 1993-02-03 | 1994-08-29 | Steven Andrew Jennings | Blends of glycine derivatives and sugars |
ES2154277T3 (es) * | 1993-07-15 | 2001-04-01 | Hoffmann La Roche | Combinacion farmaceutica que contiene un inhibidor del sistema renina-angiotensina y un antagonista de endotelina. |
GB9318637D0 (en) * | 1993-09-08 | 1993-10-27 | Ferring Res Ltd | Enzyme inhibitors |
US5508266A (en) * | 1994-06-22 | 1996-04-16 | Ciba-Geigy Corporation | Gem-disubstituted amino acid derivatives |
US6348571B1 (en) * | 1994-09-12 | 2002-02-19 | Northwestern University | Corticotropin release inhibiting factor and methods of using same |
EP0784629B1 (de) * | 1994-10-05 | 1999-04-28 | Darwin Discovery Limited | Peptidische verbindungen und deren therapeutische verwendung als metalloproteinase-inhibitoren |
US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
US5780589A (en) * | 1994-11-30 | 1998-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Ultraselective opioidmimetic peptides and pharmacological and therapeutic uses thereof |
US6037324A (en) * | 1996-01-04 | 2000-03-14 | Leukosite, Inc. | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor |
GB9601724D0 (en) * | 1996-01-29 | 1996-03-27 | Merck Sharp & Dohme | Therapeutic agents |
US5773475A (en) | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
US6126939A (en) * | 1996-09-03 | 2000-10-03 | Yeda Research And Development Co. Ltd. | Anti-inflammatory dipeptide and pharmaceutical composition thereof |
US6514937B1 (en) * | 1997-02-25 | 2003-02-04 | Celtrix Pharmaceuticals, Inc. | Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3 |
US6197746B1 (en) * | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
KR100522012B1 (ko) | 1997-07-08 | 2005-10-18 | 오노 야꾸힝 고교 가부시키가이샤 | 아미노산 유도체 |
AU7937298A (en) | 1997-07-08 | 1999-02-08 | Ono Pharmaceutical Co. Ltd. | Amino acid derivatives |
AU744899B2 (en) | 1997-07-15 | 2002-03-07 | Research Corporation Technologies, Inc. | Amino acid derivatives useful to treat stroke |
US6737408B1 (en) * | 1997-08-07 | 2004-05-18 | University Of Cincinnati | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm |
US6028102A (en) * | 1998-02-24 | 2000-02-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Anticonvulsant drugs and pharmaceutical compositions thereof |
RU2219924C2 (ru) * | 1998-04-14 | 2003-12-27 | Дзе Дженерал Хоспитал Корпорейшн | Способ лечения нейропсихиатрических расстройств |
ES2262322T3 (es) | 1998-06-10 | 2006-11-16 | Meiji Seika Kaisha, Ltd. | Tratamiento de la degenaracion espinocereberal y comoposiciones utiles para el tratamiento de degeneracion espinocerebelar. |
US6716810B1 (en) * | 1998-12-09 | 2004-04-06 | Eleanor Roosevelt Institute | Composition and method for regulation of body weight and associated conditions |
US6399574B1 (en) * | 2000-03-22 | 2002-06-04 | University Of Utah Research Foundation | Use of conantokins |
DE60142806D1 (de) | 2000-08-25 | 2010-09-23 | Res Corp Technologies Inc | Aminosäure enthaltende Antikonvulsiva zur Behandlung von Zwangsstörungen |
US6228825B1 (en) | 2000-10-13 | 2001-05-08 | Colgate Palmolive Company | Automatic dishwashing cleaning system |
EP1243262B1 (de) * | 2001-03-20 | 2006-05-31 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen bei der Behandlung von nicht-neuropathischem Entzündungsschmerz |
-
2001
- 2001-08-24 DE DE60142806T patent/DE60142806D1/de not_active Expired - Lifetime
- 2001-08-24 AU AU2001286763A patent/AU2001286763C1/en not_active Ceased
- 2001-08-24 US US09/938,677 patent/US6884910B2/en not_active Expired - Lifetime
- 2001-08-24 EP EP01966230A patent/EP1365787B1/de not_active Expired - Lifetime
- 2001-08-24 DE DE60131032T patent/DE60131032T2/de not_active Expired - Lifetime
- 2001-08-24 DE DE60127459T patent/DE60127459T2/de not_active Expired - Lifetime
- 2001-08-24 ES ES01966230T patent/ES2281439T3/es not_active Expired - Lifetime
- 2001-08-24 DK DK04021728T patent/DK1486206T3/da active
- 2001-08-24 EP EP10160637.4A patent/EP2210598B1/de not_active Expired - Lifetime
- 2001-08-24 ES ES06012400T patent/ES2348646T3/es not_active Expired - Lifetime
- 2001-08-24 DK DK06012400.5T patent/DK1695703T3/da active
- 2001-08-24 AT AT01966230T patent/ATE357227T1/de active
- 2001-08-24 ES ES04021728T patent/ES2294415T3/es not_active Expired - Lifetime
- 2001-08-24 PT PT04021727T patent/PT1486205E/pt unknown
- 2001-08-24 AT AT04021728T patent/ATE375793T1/de active
- 2001-08-24 PT PT01966230T patent/PT1365787E/pt unknown
- 2001-08-24 EP EP04021727A patent/EP1486205B1/de not_active Expired - Lifetime
- 2001-08-24 DK DK04021727T patent/DK1486205T3/da active
- 2001-08-24 PT PT06012400T patent/PT1695703E/pt unknown
- 2001-08-24 ES ES10160637T patent/ES2435000T3/es not_active Expired - Lifetime
- 2001-08-24 CA CA2740815A patent/CA2740815C/en not_active Expired - Fee Related
- 2001-08-24 EP EP04021728A patent/EP1486206B1/de not_active Expired - Lifetime
- 2001-08-24 WO PCT/US2001/026568 patent/WO2002015922A2/en active IP Right Grant
- 2001-08-24 DE DE60131033T patent/DE60131033T2/de not_active Expired - Lifetime
- 2001-08-24 ES ES04021727T patent/ES2294414T3/es not_active Expired - Lifetime
- 2001-08-24 AT AT06012400T patent/ATE476971T1/de active
- 2001-08-24 EP EP06012400A patent/EP1695703B1/de not_active Expired - Lifetime
- 2001-08-24 AU AU8676301A patent/AU8676301A/xx active Pending
- 2001-08-24 JP JP2002520843A patent/JP4307068B2/ja not_active Expired - Fee Related
- 2001-08-24 DK DK01966230T patent/DK1365787T3/da active
- 2001-08-24 CA CA2419285A patent/CA2419285C/en not_active Expired - Fee Related
- 2001-08-24 PT PT04021728T patent/PT1486206E/pt unknown
- 2001-08-24 AT AT04021727T patent/ATE375792T1/de active
-
2003
- 2003-10-17 US US10/688,638 patent/US7148378B2/en not_active Expired - Lifetime
- 2003-10-17 US US10/688,709 patent/US7186859B2/en not_active Expired - Fee Related
-
2007
- 2007-01-10 US US11/651,845 patent/US7772427B2/en not_active Expired - Fee Related
- 2007-05-23 AU AU2007202336A patent/AU2007202336B9/en not_active Ceased
- 2007-06-11 CY CY20071100768T patent/CY1107668T1/el unknown
-
2008
- 2008-01-11 CY CY20081100041T patent/CY1107853T1/el unknown
- 2008-01-11 CY CY20081100040T patent/CY1107852T1/el unknown
- 2008-11-28 JP JP2008304255A patent/JP5190334B2/ja not_active Expired - Fee Related
-
2009
- 2009-01-14 LU LU91512C patent/LU91512I2/fr unknown
- 2009-02-18 CY CY200900002C patent/CY2009002I1/el unknown
- 2009-06-12 AU AU2009202363A patent/AU2009202363B2/en not_active Ceased
- 2009-06-12 AU AU2009202362A patent/AU2009202362B2/en not_active Ceased
-
2010
- 2010-07-01 US US12/829,160 patent/US8519183B2/en not_active Expired - Fee Related
- 2010-11-04 CY CY20101101002T patent/CY1112349T1/el unknown
-
2011
- 2011-05-17 AU AU2011202293A patent/AU2011202293B2/en not_active Ceased
-
2013
- 2013-07-29 US US13/953,213 patent/US20130316953A1/en not_active Abandoned
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