DK1474415T3 - 1-phenyl-2-heteroaryl-substituerede benzimidazolderivater, deres anvendelse til fremstilling af lægemidler til behandling af immunologiske sygdomme - Google Patents

1-phenyl-2-heteroaryl-substituerede benzimidazolderivater, deres anvendelse til fremstilling af lægemidler til behandling af immunologiske sygdomme

Info

Publication number
DK1474415T3
DK1474415T3 DK03702464.3T DK03702464T DK1474415T3 DK 1474415 T3 DK1474415 T3 DK 1474415T3 DK 03702464 T DK03702464 T DK 03702464T DK 1474415 T3 DK1474415 T3 DK 1474415T3
Authority
DK
Denmark
Prior art keywords
heteroaryl
drugs
phenyl
manufacture
treatment
Prior art date
Application number
DK03702464.3T
Other languages
English (en)
Inventor
Thorsten Blume
Wolfgang Halfbrodt
Joachim Kuhnke
Ursula Moenning
Bernd Elger
Herbert Schneider
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Application granted granted Critical
Publication of DK1474415T3 publication Critical patent/DK1474415T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
DK03702464.3T 2002-02-15 2003-01-17 1-phenyl-2-heteroaryl-substituerede benzimidazolderivater, deres anvendelse til fremstilling af lægemidler til behandling af immunologiske sygdomme DK1474415T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10207844A DE10207844A1 (de) 2002-02-15 2002-02-15 1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
PCT/EP2003/000462 WO2003068766A1 (de) 2002-02-15 2003-01-17 1-phenyl-2-heteroaryl-substituierte benzimidazolderivate, deren verwendung zur herstellung von arzneimitteln zur behandlung von immunologischen erkrankungen

Publications (1)

Publication Number Publication Date
DK1474415T3 true DK1474415T3 (da) 2011-11-21

Family

ID=27674913

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03702464.3T DK1474415T3 (da) 2002-02-15 2003-01-17 1-phenyl-2-heteroaryl-substituerede benzimidazolderivater, deres anvendelse til fremstilling af lægemidler til behandling af immunologiske sygdomme

Country Status (30)

Country Link
EP (1) EP1474415B1 (da)
JP (1) JP4739675B2 (da)
KR (1) KR101027556B1 (da)
CN (1) CN1317274C (da)
AR (1) AR038492A1 (da)
AT (1) ATE517881T1 (da)
AU (1) AU2003205624B2 (da)
BR (1) BR0307723A (da)
CA (1) CA2475780C (da)
CR (1) CR7442A (da)
CY (1) CY1113230T1 (da)
DE (1) DE10207844A1 (da)
DK (1) DK1474415T3 (da)
EC (1) ECSP045296A (da)
ES (1) ES2369662T3 (da)
IL (1) IL163431A (da)
MX (1) MXPA04007949A (da)
NO (1) NO329667B1 (da)
NZ (1) NZ534660A (da)
PE (1) PE20030941A1 (da)
PL (1) PL216233B1 (da)
PT (1) PT1474415E (da)
RS (1) RS51831B (da)
RU (1) RU2325384C2 (da)
SI (1) SI1474415T1 (da)
TW (1) TWI328583B (da)
UA (1) UA81243C2 (da)
UY (1) UY27661A1 (da)
WO (1) WO2003068766A1 (da)
ZA (1) ZA200407381B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101020399B1 (ko) 2002-03-27 2011-03-08 글락소 그룹 리미티드 퀴놀린 유도체 및 5-ｈｔ6 리간드로서의 그의 용도
JP4575920B2 (ja) * 2003-05-19 2010-11-04 アイアールエム・リミテッド・ライアビリティ・カンパニー 免疫抑制化合物および組成物
WO2014044611A1 (en) 2012-09-20 2014-03-27 Bayer Pharma Aktiengesellschaft 1-aryl-2-heteroaryl benzimidazoles for the induction of neuronal regeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330959A1 (de) * 1993-09-09 1995-03-16 Schering Ag Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
CN1301975C (zh) 2000-01-14 2007-02-28 舍林股份公司 用于治疗与小胶质细胞活化有关的疾病的1,2－二芳基苯并咪唑衍生物
US7115645B2 (en) * 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
DE10207843A1 (de) * 2002-02-15 2003-09-04 Schering Ag Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen

Also Published As

Publication number Publication date
CA2475780A1 (en) 2003-08-21
AU2003205624B2 (en) 2009-08-27
UA81243C2 (en) 2007-12-25
AU2003205624A1 (en) 2003-09-04
PL216233B1 (pl) 2014-03-31
KR101027556B1 (ko) 2011-04-06
CA2475780C (en) 2011-08-02
TW200303307A (en) 2003-09-01
JP2005521686A (ja) 2005-07-21
NO329667B1 (no) 2010-11-29
PL371269A1 (en) 2005-06-13
ATE517881T1 (de) 2011-08-15
ES2369662T3 (es) 2011-12-02
DE10207844A1 (de) 2003-09-04
PT1474415E (pt) 2011-10-13
RU2325384C2 (ru) 2008-05-27
ECSP045296A (es) 2004-10-26
RS51831B (en) 2012-02-29
MXPA04007949A (es) 2004-11-26
SI1474415T1 (sl) 2011-12-30
CN1317274C (zh) 2007-05-23
CN1633429A (zh) 2005-06-29
RS71404A (en) 2006-10-27
IL163431A (en) 2010-11-30
NO20043841L (no) 2004-11-12
CY1113230T1 (el) 2016-04-13
KR20040081795A (ko) 2004-09-22
AR038492A1 (es) 2005-01-19
EP1474415B1 (de) 2011-07-27
EP1474415A1 (de) 2004-11-10
CR7442A (es) 2006-02-06
TWI328583B (en) 2010-08-11
PE20030941A1 (es) 2004-01-17
RU2004127678A (ru) 2005-07-10
NZ534660A (en) 2006-02-24
BR0307723A (pt) 2005-01-25
WO2003068766A1 (de) 2003-08-21
JP4739675B2 (ja) 2011-08-03
ZA200407381B (en) 2005-11-30
UY27661A1 (es) 2003-09-30

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