BR0307723A - Derivados de benzimidazol substituìdos por 1-fenil-2-heteroarila, seu emprego para preparação de medicamentos bem como preparados farmacêuticos contendo esses derivados - Google Patents

Derivados de benzimidazol substituìdos por 1-fenil-2-heteroarila, seu emprego para preparação de medicamentos bem como preparados farmacêuticos contendo esses derivados

Info

Publication number
BR0307723A
BR0307723A BR0307723-3A BR0307723A BR0307723A BR 0307723 A BR0307723 A BR 0307723A BR 0307723 A BR0307723 A BR 0307723A BR 0307723 A BR0307723 A BR 0307723A
Authority
BR
Brazil
Prior art keywords
derivatives
preparation
medicaments
well
pharmaceutical preparations
Prior art date
Application number
BR0307723-3A
Other languages
English (en)
Inventor
Thorsten Blume
Wolfgang Halfbrodt
Joachim Kuhnke
Ursula Moenning
Bernd Elger
Herbert Schneider
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0307723A publication Critical patent/BR0307723A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS DE BENZIMIDAZOL SUBSTITUìDOS POR 1-FENIL-2-HETEROARILA, SEU EMPREGO PARA PREPARAçãO DE MEDICAMENTOS BEM COMO PREPARADOS FARMACêUTICOS CONTENDO ESSES DERIVADOS". A presente invenção refere-se a derivados de benzimidazóis, sua preparação e seu emprego para preparação de medicamentos para tratamento e profilaxia de doenças que estão associadas com uma ativação de microglias e doenças imunológicas mediadas por células T, assim como preparados farmacêuticos que contêm os novos derivados de benzimidazol.
BR0307723-3A 2002-02-15 2003-01-17 Derivados de benzimidazol substituìdos por 1-fenil-2-heteroarila, seu emprego para preparação de medicamentos bem como preparados farmacêuticos contendo esses derivados BR0307723A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10207844A DE10207844A1 (de) 2002-02-15 2002-02-15 1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
PCT/EP2003/000462 WO2003068766A1 (de) 2002-02-15 2003-01-17 1-phenyl-2-heteroaryl-substituierte benzimidazolderivate, deren verwendung zur herstellung von arzneimitteln zur behandlung von immunologischen erkrankungen

Publications (1)

Publication Number Publication Date
BR0307723A true BR0307723A (pt) 2005-01-25

Family

ID=27674913

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307723-3A BR0307723A (pt) 2002-02-15 2003-01-17 Derivados de benzimidazol substituìdos por 1-fenil-2-heteroarila, seu emprego para preparação de medicamentos bem como preparados farmacêuticos contendo esses derivados

Country Status (30)

Country Link
EP (1) EP1474415B1 (pt)
JP (1) JP4739675B2 (pt)
KR (1) KR101027556B1 (pt)
CN (1) CN1317274C (pt)
AR (1) AR038492A1 (pt)
AT (1) ATE517881T1 (pt)
AU (1) AU2003205624B2 (pt)
BR (1) BR0307723A (pt)
CA (1) CA2475780C (pt)
CR (1) CR7442A (pt)
CY (1) CY1113230T1 (pt)
DE (1) DE10207844A1 (pt)
DK (1) DK1474415T3 (pt)
EC (1) ECSP045296A (pt)
ES (1) ES2369662T3 (pt)
IL (1) IL163431A (pt)
MX (1) MXPA04007949A (pt)
NO (1) NO329667B1 (pt)
NZ (1) NZ534660A (pt)
PE (1) PE20030941A1 (pt)
PL (1) PL216233B1 (pt)
PT (1) PT1474415E (pt)
RS (1) RS51831B (pt)
RU (1) RU2325384C2 (pt)
SI (1) SI1474415T1 (pt)
TW (1) TWI328583B (pt)
UA (1) UA81243C2 (pt)
UY (1) UY27661A1 (pt)
WO (1) WO2003068766A1 (pt)
ZA (1) ZA200407381B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535239A (en) 2002-03-27 2008-03-28 Glaxo Group Ltd Quinoline derivatives and their use as 5-HT6 ligands
BRPI0410454A (pt) * 2003-05-19 2006-06-13 Irm Llc composições e compostos imunossupressores
WO2014044611A1 (en) 2012-09-20 2014-03-27 Bayer Pharma Aktiengesellschaft 1-aryl-2-heteroaryl benzimidazoles for the induction of neuronal regeneration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330959A1 (de) * 1993-09-09 1995-03-16 Schering Ag Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
MXPA02005742A (es) * 2000-01-14 2002-09-18 Schering Ag 1,2-diaril bencimidazoles para el tratamiento de enfermedades asociadas con la activacion de la micrologia.
US7115645B2 (en) * 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
DE10207843A1 (de) * 2002-02-15 2003-09-04 Schering Ag Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen

Also Published As

Publication number Publication date
CA2475780C (en) 2011-08-02
PL371269A1 (en) 2005-06-13
SI1474415T1 (sl) 2011-12-30
PL216233B1 (pl) 2014-03-31
MXPA04007949A (es) 2004-11-26
KR101027556B1 (ko) 2011-04-06
TWI328583B (en) 2010-08-11
CR7442A (es) 2006-02-06
JP2005521686A (ja) 2005-07-21
JP4739675B2 (ja) 2011-08-03
IL163431A (en) 2010-11-30
NO20043841L (no) 2004-11-12
EP1474415B1 (de) 2011-07-27
PE20030941A1 (es) 2004-01-17
CA2475780A1 (en) 2003-08-21
AR038492A1 (es) 2005-01-19
RU2325384C2 (ru) 2008-05-27
DE10207844A1 (de) 2003-09-04
WO2003068766A1 (de) 2003-08-21
ATE517881T1 (de) 2011-08-15
CY1113230T1 (el) 2016-04-13
NZ534660A (en) 2006-02-24
DK1474415T3 (da) 2011-11-21
UY27661A1 (es) 2003-09-30
KR20040081795A (ko) 2004-09-22
RS51831B (en) 2012-02-29
RU2004127678A (ru) 2005-07-10
CN1633429A (zh) 2005-06-29
UA81243C2 (en) 2007-12-25
CN1317274C (zh) 2007-05-23
PT1474415E (pt) 2011-10-13
NO329667B1 (no) 2010-11-29
ES2369662T3 (es) 2011-12-02
EP1474415A1 (de) 2004-11-10
AU2003205624B2 (en) 2009-08-27
ZA200407381B (en) 2005-11-30
AU2003205624A1 (en) 2003-09-04
TW200303307A (en) 2003-09-01
ECSP045296A (es) 2004-10-26
RS71404A (en) 2006-10-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25D Requested change of name of applicant approved

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE)

B25D Requested change of name of applicant approved

Owner name: BAYER PHARMA AKTIENGESELLSCHAFT (DE)

B25A Requested transfer of rights approved

Owner name: BAYER INTELLECTUAL PROPERTY GMBH. (DE)

B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 13A E 14A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]