DK1292591T3 - Bicykliske derivater til behandling af abnorm cellevækst - Google Patents

Bicykliske derivater til behandling af abnorm cellevækst

Info

Publication number
DK1292591T3
DK1292591T3 DK01938484T DK01938484T DK1292591T3 DK 1292591 T3 DK1292591 T3 DK 1292591T3 DK 01938484 T DK01938484 T DK 01938484T DK 01938484 T DK01938484 T DK 01938484T DK 1292591 T3 DK1292591 T3 DK 1292591T3
Authority
DK
Denmark
Prior art keywords
treatment
cell growth
abnormal cell
bicyclic derivatives
bicyclic
Prior art date
Application number
DK01938484T
Other languages
Danish (da)
English (en)
Inventor
John Charles Kath
Samit Kumar Bhattacharya
Joel Morris
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1292591T3 publication Critical patent/DK1292591T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK01938484T 2000-06-22 2001-06-14 Bicykliske derivater til behandling af abnorm cellevækst DK1292591T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21313600P 2000-06-22 2000-06-22
PCT/IB2001/001046 WO2001098277A2 (fr) 2000-06-22 2001-06-14 Derives bicycliques substitues destines au traitement de la croissance cellulaire anormale

Publications (1)

Publication Number Publication Date
DK1292591T3 true DK1292591T3 (da) 2005-05-30

Family

ID=22793862

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01938484T DK1292591T3 (da) 2000-06-22 2001-06-14 Bicykliske derivater til behandling af abnorm cellevækst

Country Status (43)

Country Link
US (2) US6890924B2 (fr)
EP (1) EP1292591B1 (fr)
JP (1) JP4044839B2 (fr)
KR (1) KR100545537B1 (fr)
CN (3) CN1437594A (fr)
AP (1) AP2001002192A0 (fr)
AR (1) AR032353A1 (fr)
AT (1) ATE288431T1 (fr)
AU (1) AU2001264159A1 (fr)
BG (1) BG107269A (fr)
BR (1) BR0111548A (fr)
CA (1) CA2413424C (fr)
CZ (1) CZ20023951A3 (fr)
DE (1) DE60108754T2 (fr)
DK (1) DK1292591T3 (fr)
DZ (1) DZ3407A1 (fr)
EA (1) EA005525B1 (fr)
EC (1) ECSP024393A (fr)
EE (1) EE200200710A (fr)
ES (1) ES2236240T3 (fr)
GE (1) GEP20063831B (fr)
HK (1) HK1069576A1 (fr)
HR (1) HRP20021005A2 (fr)
HU (1) HUP0301120A2 (fr)
IL (1) IL152985A0 (fr)
IS (1) IS6616A (fr)
MA (1) MA26914A1 (fr)
MX (1) MXPA02012870A (fr)
MY (1) MY127181A (fr)
NO (1) NO20026166D0 (fr)
NZ (1) NZ522568A (fr)
OA (1) OA12291A (fr)
PA (1) PA8520301A1 (fr)
PE (1) PE20020257A1 (fr)
PL (1) PL359557A1 (fr)
PT (1) PT1292591E (fr)
SK (1) SK17102002A3 (fr)
SV (1) SV2002000504A (fr)
TN (1) TNSN01091A1 (fr)
UA (1) UA73990C2 (fr)
WO (1) WO2001098277A2 (fr)
YU (1) YU95102A (fr)
ZA (1) ZA200210231B (fr)

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EA005525B1 (ru) 2005-04-28
PT1292591E (pt) 2005-06-30
CA2413424A1 (fr) 2001-12-27
KR100545537B1 (ko) 2006-01-25
ATE288431T1 (de) 2005-02-15
PA8520301A1 (es) 2003-06-30
WO2001098277A3 (fr) 2002-06-13
US20050159435A1 (en) 2005-07-21
CN1330640C (zh) 2007-08-08
SV2002000504A (es) 2002-10-24
CZ20023951A3 (cs) 2004-01-14
ECSP024393A (es) 2003-02-06
MXPA02012870A (es) 2003-05-14
PL359557A1 (en) 2004-08-23
TNSN01091A1 (fr) 2005-11-10
NO20026166L (no) 2002-12-20
NO20026166D0 (no) 2002-12-20
SK17102002A3 (sk) 2004-04-06
IL152985A0 (en) 2003-06-24
HUP0301120A2 (hu) 2003-08-28
CN1437594A (zh) 2003-08-20
EE200200710A (et) 2004-06-15
US6890924B2 (en) 2005-05-10
US20020169165A1 (en) 2002-11-14
EP1292591B1 (fr) 2005-02-02
DZ3407A1 (fr) 2001-12-27
EA200201277A1 (ru) 2003-06-26
CN1576275A (zh) 2005-02-09
DE60108754D1 (de) 2005-03-10
HRP20021005A2 (en) 2004-02-29
HK1069576A1 (en) 2005-05-27
BG107269A (bg) 2003-06-30
AR032353A1 (es) 2003-11-05
AU2001264159A1 (en) 2002-01-02
IS6616A (is) 2002-11-14
PE20020257A1 (es) 2002-04-08
ES2236240T3 (es) 2005-07-16
ZA200210231B (en) 2004-02-12
CN101348467A (zh) 2009-01-21
NZ522568A (en) 2004-12-24
JP4044839B2 (ja) 2008-02-06
KR20030016303A (ko) 2003-02-26
YU95102A (sh) 2005-11-28
EP1292591A2 (fr) 2003-03-19
MY127181A (en) 2006-11-30
UA73990C2 (en) 2005-10-17
MA26914A1 (fr) 2004-12-20
BR0111548A (pt) 2003-05-06
DE60108754T2 (de) 2005-06-23
GEP20063831B (en) 2006-05-25
CA2413424C (fr) 2007-10-02
US7332493B2 (en) 2008-02-19
OA12291A (en) 2004-03-18
JP2004501139A (ja) 2004-01-15
WO2001098277A2 (fr) 2001-12-27
AP2001002192A0 (en) 2002-12-21

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