DK116889D0 - Fremgangsmaade til fremstilling af 3-exomethylencephamderivater - Google Patents

Fremgangsmaade til fremstilling af 3-exomethylencephamderivater

Info

Publication number
DK116889D0
DK116889D0 DK116889A DK116889A DK116889D0 DK 116889 D0 DK116889 D0 DK 116889D0 DK 116889 A DK116889 A DK 116889A DK 116889 A DK116889 A DK 116889A DK 116889 D0 DK116889 D0 DK 116889D0
Authority
DK
Denmark
Prior art keywords
derivatives
cephem
exomethylencepham
preparing
procedure
Prior art date
Application number
DK116889A
Other languages
English (en)
Other versions
DK116889A (da
Inventor
Jan Verweij
Jan Jacobus De Koning
Hendrik Adrianus Witkamp
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of DK116889A publication Critical patent/DK116889A/da
Publication of DK116889D0 publication Critical patent/DK116889D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK116889A 1987-07-13 1989-03-10 Fremgangsmaade til fremstilling af 3-exomethylencephamderivater DK116889D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87201323 1987-07-13
PCT/NL1988/000035 WO1989000572A1 (en) 1987-07-13 1988-07-13 Process for the preparation of 3-exomethylene cepham derivatives

Publications (2)

Publication Number Publication Date
DK116889A DK116889A (da) 1989-03-10
DK116889D0 true DK116889D0 (da) 1989-03-10

Family

ID=8197638

Family Applications (1)

Application Number Title Priority Date Filing Date
DK116889A DK116889D0 (da) 1987-07-13 1989-03-10 Fremgangsmaade til fremstilling af 3-exomethylencephamderivater

Country Status (19)

Country Link
US (3) US4985554A (da)
EP (1) EP0299587B1 (da)
JP (1) JPH0742291B2 (da)
KR (1) KR0137221B1 (da)
CN (1) CN1040441C (da)
AT (1) ATE113952T1 (da)
AU (1) AU619201B2 (da)
CA (1) CA1338607C (da)
DE (1) DE3852065T2 (da)
DK (1) DK116889D0 (da)
ES (1) ES2067465T3 (da)
FI (1) FI891191A (da)
HU (1) HU207865B (da)
IE (1) IE66466B1 (da)
IL (1) IL87110A (da)
NO (1) NO891044L (da)
NZ (1) NZ225388A (da)
PT (1) PT87985B (da)
WO (1) WO1989000572A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300546B1 (en) * 1987-07-10 1995-08-09 Gist-Brocades N.V. Process for the preparation of cephem compounds and cephalosporin derivatives
US5159071A (en) * 1990-09-06 1992-10-27 Ranbaxy Laboratories Limited Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
US5604222A (en) 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
AU7567596A (en) * 1995-11-06 1997-05-29 Gist-Brocades B.V. De-esterification process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731443A (en) * 1979-11-19 1988-03-15 Fujisawa Pharmaceutical Co., Ltd. 7-acylamino-3-vinylcephalosporanic acid derivatives
US4354022A (en) * 1981-06-05 1982-10-12 Fujisawa Pharmaceutical Co., Ltd. Process for preparing 3-methylenecepham compounds or a salt thereof
US4558123A (en) * 1983-07-22 1985-12-10 Eli Lilly And Company 3-Exomethylene cephalosporins
US4705851A (en) * 1984-09-28 1987-11-10 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of 3-phosphoniummethyl-3-cephem compounds

Also Published As

Publication number Publication date
US5109132A (en) 1992-04-28
NO891044D0 (no) 1989-03-10
AU2078388A (en) 1989-02-13
US4994454A (en) 1991-02-19
HU207865B (en) 1993-06-28
HUT52512A (da) 1990-07-28
WO1989000572A1 (en) 1989-01-26
EP0299587A1 (en) 1989-01-18
JPH0742291B2 (ja) 1995-05-10
FI891191A0 (fi) 1989-03-13
DE3852065T2 (de) 1995-04-06
IL87110A (en) 1993-04-04
KR890701593A (ko) 1989-12-21
FI891191A (fi) 1989-03-13
NZ225388A (en) 1991-07-26
PT87985A (pt) 1989-06-30
KR0137221B1 (ko) 1998-04-25
US4985554A (en) 1991-01-15
JPH02500843A (ja) 1990-03-22
AU619201B2 (en) 1992-01-23
IL87110A0 (en) 1988-12-30
DK116889A (da) 1989-03-10
DE3852065D1 (de) 1994-12-15
CN1031534A (zh) 1989-03-08
IE882137L (en) 1989-01-13
PT87985B (pt) 1995-03-01
ES2067465T3 (es) 1995-04-01
CN1040441C (zh) 1998-10-28
NO891044L (no) 1989-03-10
ATE113952T1 (de) 1994-11-15
IE66466B1 (en) 1995-12-27
EP0299587B1 (en) 1994-11-09
CA1338607C (en) 1996-09-24

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment