DK0581959T3 - Anvendelse af makrolidforbindelser til øjensygdomme - Google Patents

Anvendelse af makrolidforbindelser til øjensygdomme

Info

Publication number
DK0581959T3
DK0581959T3 DK92909558T DK92909558T DK0581959T3 DK 0581959 T3 DK0581959 T3 DK 0581959T3 DK 92909558 T DK92909558 T DK 92909558T DK 92909558 T DK92909558 T DK 92909558T DK 0581959 T3 DK0581959 T3 DK 0581959T3
Authority
DK
Denmark
Prior art keywords
pct
eye diseases
macrolide compounds
compounds
date
Prior art date
Application number
DK92909558T
Other languages
English (en)
Inventor
Manabu Mochizuki
Yoichi Iwaki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919109060A external-priority patent/GB9109060D0/en
Priority claimed from GB919121661A external-priority patent/GB9121661D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0581959T3 publication Critical patent/DK0581959T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK92909558T 1991-04-26 1992-04-24 Anvendelse af makrolidforbindelser til øjensygdomme DK0581959T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919109060A GB9109060D0 (en) 1991-04-26 1991-04-26 New use
GB919121661A GB9121661D0 (en) 1991-10-11 1991-10-11 New use
PCT/JP1992/000545 WO1992019278A1 (en) 1991-04-26 1992-04-24 Use of macrolide compounds for eye diseases

Publications (1)

Publication Number Publication Date
DK0581959T3 true DK0581959T3 (da) 2001-01-29

Family

ID=26298796

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92909558T DK0581959T3 (da) 1991-04-26 1992-04-24 Anvendelse af makrolidforbindelser til øjensygdomme

Country Status (11)

Country Link
US (1) US5514686A (da)
EP (1) EP0581959B1 (da)
JP (1) JP3158437B2 (da)
KR (1) KR100237715B1 (da)
AT (1) ATE198708T1 (da)
CA (1) CA2102241C (da)
DE (1) DE69231644T2 (da)
DK (1) DK0581959T3 (da)
ES (1) ES2154262T3 (da)
GR (1) GR3035269T3 (da)
WO (1) WO1992019278A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1009856A5 (fr) * 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
EP1056454B1 (en) * 1998-02-23 2003-05-02 Fujisawa Pharmaceutical Co., Ltd. Use of macrolide compounds for treating glaucoma
US6376517B1 (en) * 1998-08-14 2002-04-23 Gpi Nil Holdings, Inc. Pipecolic acid derivatives for vision and memory disorders
US6333340B1 (en) 1998-08-14 2001-12-25 Gpi Nil Holdings, Inc. Small molecule sulfonamides for vision and memory disorders
US7410995B1 (en) 1998-08-14 2008-08-12 Gpi Nil Holdings Inc. N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
US6339101B1 (en) 1998-08-14 2002-01-15 Gpi Nil Holdings, Inc. N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders
US6384056B1 (en) 1998-08-14 2002-05-07 Gpi Nil Holdings, Inc. Heterocyclic thioesters or ketones for vision and memory disorders
US6218423B1 (en) 1998-08-14 2001-04-17 Gpi Nil Holdings, Inc. Pyrrolidine derivatives for vision and memory disorders
US6399648B1 (en) 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
US6335348B1 (en) 1998-08-14 2002-01-01 Gpi Nil Holdings, Inc. Nitrogen-containing linear and azepinyl/ compositions and uses for vision and memory disorders
US6506788B1 (en) 1998-08-14 2003-01-14 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders
US7338976B1 (en) * 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
US7265150B1 (en) 1998-08-14 2007-09-04 Gpi Nil Holdings Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
US6337340B1 (en) 1998-08-14 2002-01-08 Gpi Nil Holdings, Inc. Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders
ES2232439T3 (es) * 1999-04-30 2005-06-01 Sucampo Ag Uso de compuestos macrolidos para el tratamiento de los ojos secos.
AR033151A1 (es) * 2001-04-12 2003-12-03 Sucampo Pharmaceuticals Inc Agente para el tratamiento oftalmico topico de las enfermedades inflamatorias oculares
CN1259049C (zh) * 2001-07-06 2006-06-14 苏坎波公司 包含白介素－2抑制剂和抗菌剂的局部给药组合物
EP1450798A1 (en) * 2001-11-19 2004-09-01 Novartis AG Use of an ascomycin for the treatment of blepharitis
AU2002366028A1 (en) * 2001-11-21 2003-06-10 Sucampo Ag Use of fk506 and analogues for treating allergic diseases
AU2003256068A1 (en) * 2002-08-09 2004-02-25 Sucampo Pharmaceuticals, Inc. Pharmaceutical compositions comprising fk506 derivatives and the ir use for the treatment of allergic diseases
AU2003272471B2 (en) 2002-09-18 2010-10-07 Trustees Of The University Of Pennsylvania Method of inhibiting choroidal neovascularization
WO2004062669A1 (en) * 2003-01-16 2004-07-29 Sucampo Ag Use of a macrolide compound for treating dry eye
EP1682132A1 (en) * 2003-09-18 2006-07-26 Macusight, Inc. Transscleral delivery
AU2006213673A1 (en) * 2005-02-09 2006-08-17 Santen Pharmaceutical Co., Ltd. Formulations for ocular treatment
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
CA2635797C (en) 2006-02-09 2015-03-31 Macusight, Inc. Stable formulations, and methods of their preparation and use
JP5506378B2 (ja) 2006-03-23 2014-05-28 参天製薬株式会社 血管透過性に関連する疾患または病気のための製剤および方法
ES2435197T3 (es) 2007-01-10 2013-12-16 Board Of Regents, The University Of Texas System Administración mejorada de composiciones de fármacos inmunosupresores para la administración por vía pulmonar
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
GB8616089D0 (en) * 1986-07-02 1986-08-06 Univ Manchester Organic compounds
ATE120466T1 (de) * 1987-12-09 1995-04-15 Fisons Plc Makrozyklische verbindungen.
EP0356399A3 (en) * 1988-08-26 1991-03-20 Sandoz Ag Substituted 4-azatricyclo (22.3.1.04.9) octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them
DE3906214A1 (de) * 1989-02-28 1990-08-30 Boehringer Mannheim Gmbh Verwendung von macrolactone als antiallergica
WO1990009760A1 (en) * 1989-03-02 1990-09-07 Ensoniq Corporation Apparatus and a method for fitting a hearing aid
IE64214B1 (en) * 1989-06-06 1995-07-26 Fujisawa Pharmaceutical Co Macrolides for the treatment of reversible obstructive airways diseases
US5100899A (en) * 1989-06-06 1992-03-31 Roy Calne Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
CA2032159A1 (en) * 1989-06-14 1990-12-15 Andrew J. F. Edmunds Heteroatoms-containing tricyclic compounds
ZA905202B (en) * 1989-07-05 1991-04-24 Fujisawa Pharmaceutical Co Aqueous liquid composition for external use
IL102414A (en) * 1991-07-25 1996-08-04 Univ Louisville Res Found Medicinal preparations for the treatment of ocular inflammation, containing rapamycin

Also Published As

Publication number Publication date
EP0581959A1 (en) 1994-02-09
DE69231644D1 (de) 2001-02-22
KR100237715B1 (ko) 2000-02-01
US5514686A (en) 1996-05-07
ATE198708T1 (de) 2001-02-15
CA2102241C (en) 2003-12-30
CA2102241A1 (en) 1992-10-27
EP0581959B1 (en) 2001-01-17
KR940701264A (ko) 1994-05-28
WO1992019278A1 (en) 1992-11-12
JPH07500570A (ja) 1995-01-19
GR3035269T3 (en) 2001-04-30
DE69231644T2 (de) 2001-05-23
ES2154262T3 (es) 2001-04-01
JP3158437B2 (ja) 2001-04-23

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