DE69736667D1 - Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm) - Google Patents
Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm)Info
- Publication number
- DE69736667D1 DE69736667D1 DE69736667T DE69736667T DE69736667D1 DE 69736667 D1 DE69736667 D1 DE 69736667D1 DE 69736667 T DE69736667 T DE 69736667T DE 69736667 T DE69736667 T DE 69736667T DE 69736667 D1 DE69736667 D1 DE 69736667D1
- Authority
- DE
- Germany
- Prior art keywords
- oligonucleotides
- modified
- modified oligonucleotides
- amplification
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2181896P | 1996-07-16 | 1996-07-16 | |
| US21818P | 1996-07-16 | ||
| PCT/US1997/012347 WO1998002582A2 (en) | 1996-07-16 | 1997-07-15 | Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m? |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69736667D1 true DE69736667D1 (de) | 2006-10-26 |
| DE69736667T2 DE69736667T2 (de) | 2007-09-06 |
Family
ID=21806324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69736667T Expired - Lifetime DE69736667T2 (de) | 1996-07-16 | 1997-07-15 | Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm) |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6130038A (de) |
| EP (1) | EP0912767B1 (de) |
| JP (2) | JP2000514307A (de) |
| KR (1) | KR20000023814A (de) |
| AT (1) | ATE339514T1 (de) |
| AU (1) | AU726821B2 (de) |
| CA (1) | CA2260749A1 (de) |
| DE (1) | DE69736667T2 (de) |
| DK (1) | DK0912767T3 (de) |
| ES (1) | ES2270467T3 (de) |
| WO (1) | WO1998002582A2 (de) |
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| US7070925B1 (en) | 1996-07-16 | 2006-07-04 | Gen-Probe Incorporated | Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe |
| JP3981416B2 (ja) | 1997-04-10 | 2007-09-26 | ユニバーシティ メディカル センター ナイメーヘン | Ｐｃａ３タンパク質、ｐｃａ３遺伝子、及びこれらの用途 |
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| JP2002521070A (ja) | 1998-07-31 | 2002-07-16 | ジェン−プローブ・インコーポレーテッド | 可逆的阻害プローブ |
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| US6844151B1 (en) | 1999-09-29 | 2005-01-18 | Oligos Etc. Inc. | Methods for production of arrays with modified oligonucleotide and polynucleotide compositions |
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-
1997
- 1997-07-15 AU AU37288/97A patent/AU726821B2/en not_active Expired
- 1997-07-15 CA CA002260749A patent/CA2260749A1/en not_active Abandoned
- 1997-07-15 DE DE69736667T patent/DE69736667T2/de not_active Expired - Lifetime
- 1997-07-15 DK DK97934169T patent/DK0912767T3/da active
- 1997-07-15 US US08/893,300 patent/US6130038A/en not_active Expired - Lifetime
- 1997-07-15 ES ES97934169T patent/ES2270467T3/es not_active Expired - Lifetime
- 1997-07-15 JP JP10506265A patent/JP2000514307A/ja not_active Ceased
- 1997-07-15 AT AT97934169T patent/ATE339514T1/de not_active IP Right Cessation
- 1997-07-15 EP EP97934169A patent/EP0912767B1/de not_active Expired - Lifetime
- 1997-07-15 WO PCT/US1997/012347 patent/WO1998002582A2/en active IP Right Grant
-
1999
- 1999-01-15 KR KR1019997000300A patent/KR20000023814A/ko not_active Application Discontinuation
-
2000
- 2000-03-10 US US09/523,237 patent/US6903206B1/en not_active Expired - Lifetime
-
2004
- 2004-10-26 US US10/973,162 patent/US20050106610A1/en not_active Abandoned
-
2008
- 2008-05-27 JP JP2008137832A patent/JP4527789B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000023814A (ko) | 2000-04-25 |
| US6903206B1 (en) | 2005-06-07 |
| ES2270467T3 (es) | 2007-04-01 |
| JP4527789B2 (ja) | 2010-08-18 |
| JP2008283973A (ja) | 2008-11-27 |
| ATE339514T1 (de) | 2006-10-15 |
| US6130038A (en) | 2000-10-10 |
| CA2260749A1 (en) | 1998-01-22 |
| JP2000514307A (ja) | 2000-10-31 |
| WO1998002582A2 (en) | 1998-01-22 |
| AU3728897A (en) | 1998-02-09 |
| AU726821B2 (en) | 2000-11-23 |
| EP0912767A2 (de) | 1999-05-06 |
| EP0912767B1 (de) | 2006-09-13 |
| WO1998002582A3 (en) | 1998-07-02 |
| US20050106610A1 (en) | 2005-05-19 |
| DK0912767T3 (da) | 2006-10-30 |
| DE69736667T2 (de) | 2007-09-06 |
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