DE69313869D1 - Verfahren zur Herstellung von Kalium Clavulanat - Google Patents

Verfahren zur Herstellung von Kalium Clavulanat

Info

Publication number: DE69313869D1
Authority: DE; Germany
Prior art keywords: production; potassium clavulanate; clavulanate; potassium
Prior art date: 1992-06-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69313869T

Other languages

English (en)

Other versions

DE69313869T2 (de

Inventor

Michael Allen Cook

Robert Bennett Wilkins

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Ltd

Original Assignee

SmithKline Beecham Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-11

Filing date

1993-06-07

Publication date

1997-10-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27450891&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69313869(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-06-11 Priority claimed from GB929212379A external-priority patent/GB9212379D0/en

1992-10-31 Priority claimed from GB929222841A external-priority patent/GB9222841D0/en

1992-12-14 Priority claimed from GB929226061A external-priority patent/GB9226061D0/en

1992-12-17 Priority claimed from GB929226282A external-priority patent/GB9226282D0/en

1993-06-07 Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd

1997-10-16 Application granted granted Critical

1997-10-16 Publication of DE69313869D1 publication Critical patent/DE69313869D1/de

1998-01-29 Publication of DE69313869T2 publication Critical patent/DE69313869T2/de

2013-06-08 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60C—VEHICLE TYRES; TYRE INFLATION; TYRE CHANGING; CONNECTING VALVES TO INFLATABLE ELASTIC BODIES IN GENERAL; DEVICES OR ARRANGEMENTS RELATED TO TYRES
- B60C27/00—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels
- B60C27/006—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels provided with protective parts, e.g. rubber elements to protect the rim portion
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60C—VEHICLE TYRES; TYRE INFLATION; TYRE CHANGING; CONNECTING VALVES TO INFLATABLE ELASTIC BODIES IN GENERAL; DEVICES OR ARRANGEMENTS RELATED TO TYRES
- B60C27/00—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels
- B60C27/06—Non-skid devices temporarily attachable to resilient tyres or resiliently-tyred wheels extending over the complete circumference of the tread, e.g. made of chains or cables

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Mechanical Engineering (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69313869T 1992-06-11 1993-06-07 Herstellung von Clavulansäure via Tert.-Octylamin Expired - Fee Related DE69313869T2 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB929212379A GB9212379D0 (en)	1992-06-11	1992-06-11	Novel process
GB929222841A GB9222841D0 (en)	1992-10-31	1992-10-31	Novel process
GB929226061A GB9226061D0 (en)	1992-12-14	1992-12-14	Novel process
GB929226282A GB9226282D0 (en)	1992-12-17	1992-12-17	Novel process

Publications (2)

Publication Number	Publication Date
DE69313869D1 true DE69313869D1 (de)	1997-10-16
DE69313869T2 DE69313869T2 (de)	1998-01-29

Family

ID=27450891

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
DE69301571T Expired - Fee Related DE69301571T2 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure
DE4345311A Expired - Lifetime DE4345311C1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung und/oder Reinigung von Clavulansäure
DE4345286A Ceased DE4345286A1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure
DE69306574T Expired - Fee Related DE69306574T2 (de)	1992-06-11	1993-06-07	Zwischenprodukte in einem verfahren zur reinigung von clavulansäure
DE69313869T Expired - Fee Related DE69313869T2 (de)	1992-06-11	1993-06-07	Herstellung von Clavulansäure via Tert.-Octylamin
DE4392664T Withdrawn DE4392664T1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure

Family Applications Before (4)

Application Number	Title	Priority Date	Filing Date
DE69301571T Expired - Fee Related DE69301571T2 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure
DE4345311A Expired - Lifetime DE4345311C1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung und/oder Reinigung von Clavulansäure
DE4345286A Ceased DE4345286A1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure
DE69306574T Expired - Fee Related DE69306574T2 (de)	1992-06-11	1993-06-07	Zwischenprodukte in einem verfahren zur reinigung von clavulansäure

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE4392664T Withdrawn DE4392664T1 (de)	1992-06-11	1993-06-07	Verfahren zur Herstellung von Clavulansäure

Country Status (35)

Country	Link
EP (7)	EP0747383A3 (de)
JP (3)	JPH07507324A (de)
KR (1)	KR0162264B1 (de)
CN (3)	CN1037967C (de)
AP (3)	AP471A (de)
AT (3)	ATE146180T1 (de)
AU (3)	AU4342793A (de)
BG (3)	BG60999B1 (de)
CA (2)	CA2117538A1 (de)
CS (1)	CS202194A3 (de)
CY (1)	CY1895A (de)
CZ (5)	CZ19396A3 (de)
DE (6)	DE69301571T2 (de)
DK (5)	DK0644887T3 (de)
ES (3)	ES2106615T3 (de)
FI (7)	FI944031A (de)
GB (2)	GB2287026B (de)
GR (4)	GR950300070T1 (de)
HK (4)	HK6996A (de)
HU (3)	HU9501214D0 (de)
IL (1)	IL105966A (de)
LU (1)	LU88567A1 (de)
MA (1)	MA22907A1 (de)
MX (1)	MX9303441A (de)
MY (1)	MY131501A (de)
NL (1)	NL9320037A (de)
NO (3)	NO943093L (de)
PT (2)	PT101710A (de)
RO (3)	RO111191B1 (de)
RU (1)	RU2081121C1 (de)
SE (5)	SE9404290L (de)
SI (1)	SI9300296B (de)
SK (3)	SK278367B6 (de)
UY (1)	UY24154A1 (de)
WO (1)	WO1993025557A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT400033B (de)	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl)	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) *	1992-10-21	1999-06-15	김충환	클라불란산 칼륨염의 제조방법
US5821364A (en) *	1993-03-26	1998-10-13	Gist-Brocades N.V.	Diamine salts of clavulanic acid
AU682030B2 (en) *	1993-03-26	1997-09-18	Dsm N.V.	Diamine salts of clavulanic acid
US5760218A (en) *	1993-03-26	1998-06-02	Gist-Brocades N.V.	Diamine salts of clavulanic acid
US5741903A (en) *	1993-03-26	1998-04-21	Gist-Brocades N.V.	Diamine salts for purification of clavulanic acid
ES2155839T3 (es)	1993-11-17	2001-06-01	Biochemie Gmbh	Separacion de isomeros de cefalosporina.
SI9400107A (en) *	1994-03-02	1995-10-31	Lek Tovarna Farmacevtskih	New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) *	1994-12-24	1995-02-22	Spurcourt Ltd	Clavulanic acid salts
IL117217A0 (en) *	1995-02-25	1996-06-18	Spurcourt Ltd	Clavulanic acid salts
SI9500134B (sl)	1995-04-20	2004-04-30	Lek,	Postopek za pripravo čistih alkalijskih soli klavulanske kisline
GB9515809D0 (en) *	1995-08-02	1995-10-04	Smithkline Beecham Plc	Process
SI9500265A1 (en)	1995-08-28	1997-02-28	Lek Tovarna Farmacevtskih	Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
AT403375B (de) *	1995-11-15	1998-01-26	Biochemie Gmbh	Verfahren zur fällung von alkalisalzen der clavulansäure
US6414142B1 (en)	1996-06-13	2002-07-02	Smithkline Beecham Corporation	Process for preparing potassium clavulanate
WO1998021212A1 (en) *	1996-11-11	1998-05-22	Gist-Brocades B.V.	Process for the preparation of salts and esters of clavulanic acid
AT404728B (de) *	1996-11-27	1999-02-25	Biochemie Gmbh	Verfahren zur herstellung von clavulansäure-aminsalzen
DZ2456A1 (fr) *	1997-04-04	2003-01-18	Smithkline Beecham Plc	Procédé de préparation de sels de l'acide clavulanique.
WO2000004028A1 (en) *	1998-07-16	2000-01-27	Dsm N.V.	Improved process for the preparation of salts and esters of clavulanic acid
US6440708B1 (en)	1998-09-29	2002-08-27	Dsm N.V.	Fermentation of clavulanic acid at a controlled level of ammonia
DE19917428A1 (de) *	1999-04-19	2000-10-26	Clariant Gmbh	Flammwidrige phosphormodifizierte Epoxidharze
GB0003305D0 (en)	2000-02-15	2000-04-05	Zeneca Ltd	Pyrimidine derivatives
DE60105016T3 (de)	2000-05-13	2009-06-25	Smithkline Beecham P.L.C., Brentford	Verfahren zur reinigung eines salzes der clavulansäure
ITMI20011764A1 (it)	2001-08-10	2003-02-10	Dinamite Dipharma Spa	Metodo per l'ottenimento del pemirolast ad elevata purezza
GB201010439D0 (en) *	2010-06-21	2010-08-04	Arch Timber Protection Ltd	A method
CN103304583B (zh) *	2013-07-09	2016-01-20	山东新时代药业有限公司	一种从克拉维酸胺盐结晶母液中回收克拉维酸的方法
CN105384758B (zh) *	2015-12-01	2018-05-01	国药集团威奇达药业有限公司	克拉维酸胺盐的制备方法
JP6835211B2 (ja)	2017-04-19	2021-02-24	日本軽金属株式会社	Ａｌ−Ｓｉ−Ｆｅ系アルミニウム合金鋳造材及びその製造方法
CN109305978A (zh) *	2017-07-26	2019-02-05	山东睿鹰先锋制药有限公司	一种制备克拉维酸盐的新方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1508977A (en)	1974-04-20	1978-04-26	Beecham Group Ltd	Beta-lactam antibiotic from streptomyces clavuligerus
GB1507978A (en)	1974-03-28	1978-04-19	Dunlop Ltd	Pneumatic tyre and wheel rim assemblies
GB1543563A (en) *	1975-02-07	1979-04-04	Glaxo Lab Ltd	Beta-lactam antibiotic in purified form
GB1508978A (en)	1975-04-11	1978-04-26	Beecham Group Ltd	Esters of clavulanic acid
GB1578739A (en)	1976-07-23	1980-11-05	Beecham Group Ltd	Amine salts of clavulanic acid methods for their preparation and compositions containing them
DE2861607D1 (en) *	1977-11-26	1982-03-11	Beecham Group Plc	Derivatives of clavulanic acid and pharmaceutical compositions containing them
BE862211A (fr)	1977-12-22	1978-06-22	Beecham Group Ltd	Agents antibacteriens
JPS5562993A (en)	1978-11-07	1980-05-12	Idemitsu Petrochem Co Ltd	Operation of olefin manufacturing equipment
JPS55162993A (en)	1979-06-07	1980-12-18	Sanraku Inc	Preparation of culavulanic acid
DE3063683D1 (en)	1979-08-24	1983-07-14	Beecham Group Plc	Amine salt of clavulanic acid, its preparation and use
NZ213963A (en) *	1984-10-27	1989-01-06	Antibioticos Sa	Production of clavulanic acid
ES2010143A6 (es)	1989-03-01	1989-10-16	Pharma Mar S A Pharmar	Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
FR2644543A1 (de)	1989-03-17	1990-09-21	Renault
PT94908B (pt)	1990-08-03	1998-05-29	Portela & Ca Lda	Processo para a preparacao de derivados carboxilicos beta-lactamicos altamente purificados estaveis e hipoalergenicos
AT400033B (de) *	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) *	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) *	1992-10-21	1999-06-15	김충환	클라불란산 칼륨염의 제조방법
GB9305565D0 (en) *	1993-03-18	1993-05-05	Smithkline Beecham Plc	Novel compounds and processes
AU682030B2 (en) *	1993-03-26	1997-09-18	Dsm N.V.	Diamine salts of clavulanic acid
EP0887178A1 (de)	1997-06-27	1998-12-30	Pamag Ag	Verfahren zum Bündeln von Seitenfaltbeuteln und Vorrichtung zur Durchführung des Verfahrens

1993
- 1993-06-03 SI SI9300296A patent/SI9300296B/sl unknown
- 1993-06-07 HU HU9501214A patent/HU9501214D0/hu not_active Application Discontinuation
- 1993-06-07 DK DK93913311.2T patent/DK0644887T3/da active
- 1993-06-07 SK SK1533-94A patent/SK278367B6/sk unknown
- 1993-06-07 WO PCT/GB1993/001206 patent/WO1993025557A1/en not_active Application Discontinuation
- 1993-06-07 EP EP96202593A patent/EP0747383A3/de not_active Withdrawn
- 1993-06-07 RU RU9595112522A patent/RU2081121C1/ru active
- 1993-06-07 RO RO94-01806A patent/RO111191B1/ro unknown
- 1993-06-07 CZ CZ96193A patent/CZ19396A3/cs unknown
- 1993-06-07 AT AT93913311T patent/ATE146180T1/de not_active IP Right Cessation
- 1993-06-07 EP EP95201085A patent/EP0672670B1/de not_active Revoked
- 1993-06-07 CZ CZ942675A patent/CZ267594A3/cs unknown
- 1993-06-07 SK SK994-94A patent/SK278561B6/sk unknown
- 1993-06-07 ES ES95201084T patent/ES2106615T3/es not_active Expired - Lifetime
- 1993-06-07 RO RO95-00659A patent/RO111192B1/ro unknown
- 1993-06-07 PT PT101710A patent/PT101710A/pt not_active IP Right Cessation
- 1993-06-07 HU HU9402405A patent/HUT69374A/hu unknown
- 1993-06-07 HU HU9500610A patent/HU212583B/hu not_active IP Right Cessation
- 1993-06-07 GB GB9508497A patent/GB2287026B/en not_active Expired - Fee Related
- 1993-06-07 EP EP95117448A patent/EP0699682A1/de not_active Withdrawn
- 1993-06-07 CS CZ942021A patent/CS202194A3/cs unknown
- 1993-06-07 DE DE69301571T patent/DE69301571T2/de not_active Expired - Fee Related
- 1993-06-07 DE DE4345311A patent/DE4345311C1/de not_active Expired - Lifetime
- 1993-06-07 CZ CZ95544A patent/CZ54495A3/cs unknown
- 1993-06-07 NL NL9320037A patent/NL9320037A/nl not_active Application Discontinuation
- 1993-06-07 AT AT95201084T patent/ATE157981T1/de not_active IP Right Cessation
- 1993-06-07 DK DK95201084.1T patent/DK0672669T3/da active
- 1993-06-07 DE DE4345286A patent/DE4345286A1/de not_active Ceased
- 1993-06-07 DK DK95201085.8T patent/DK0672670T3/da active
- 1993-06-07 ES ES93913311T patent/ES2095059T3/es not_active Expired - Lifetime
- 1993-06-07 GB GB9508496A patent/GB2287025B/en not_active Expired - Fee Related
- 1993-06-07 EP EP97201887A patent/EP0806426A1/de not_active Withdrawn
- 1993-06-07 ES ES95201085T patent/ES2080710T3/es not_active Expired - Lifetime
- 1993-06-07 EP EP97201652A patent/EP0801069A1/de not_active Withdrawn
- 1993-06-07 DE DE69306574T patent/DE69306574T2/de not_active Expired - Fee Related
- 1993-06-07 JP JP6501253A patent/JPH07507324A/ja active Pending
- 1993-06-07 DE DE69313869T patent/DE69313869T2/de not_active Expired - Fee Related
- 1993-06-07 CZ CZ951254A patent/CZ281102B6/cs not_active IP Right Cessation
- 1993-06-07 CA CA002117538A patent/CA2117538A1/en not_active Abandoned
- 1993-06-07 CZ CZ942676A patent/CZ267694A3/cs unknown
- 1993-06-07 EP EP95201084A patent/EP0672669B1/de not_active Expired - Lifetime
- 1993-06-07 CA CA002160768A patent/CA2160768A1/en not_active Abandoned
- 1993-06-07 EP EP93913311A patent/EP0644887B1/de not_active Expired - Lifetime
- 1993-06-07 AU AU43427/93A patent/AU4342793A/en not_active Abandoned
- 1993-06-07 PT PT101711A patent/PT101711A/pt not_active Application Discontinuation
- 1993-06-07 RO RO95-00880A patent/RO111193B1/ro unknown
- 1993-06-07 SK SK1532-94A patent/SK278520B6/sk unknown
- 1993-06-07 KR KR1019940703225A patent/KR0162264B1/ko not_active IP Right Cessation
- 1993-06-07 AT AT95201085T patent/ATE134192T1/de not_active IP Right Cessation
- 1993-06-07 DE DE4392664T patent/DE4392664T1/de not_active Withdrawn
- 1993-06-08 MY MYPI93001142A patent/MY131501A/en unknown
- 1993-06-09 MA MA23206A patent/MA22907A1/fr unknown
- 1993-06-09 IL IL105966A patent/IL105966A/xx not_active IP Right Cessation
- 1993-06-09 MX MX9303441A patent/MX9303441A/es not_active IP Right Cessation
- 1993-06-10 AP APAP/P/1993/000537A patent/AP471A/en active
- 1993-06-10 AP APAP/P/1995/000737A patent/AP473A/en active
- 1993-06-10 CN CN93106612A patent/CN1037967C/zh not_active Expired - Fee Related
- 1993-06-10 AP APAP/P/1995/000738A patent/AP474A/en active
1994
- 1994-08-22 NO NO943093A patent/NO943093L/no unknown
- 1994-09-02 FI FI944031A patent/FI944031A/fi not_active Application Discontinuation
- 1994-10-20 BG BG99131A patent/BG60999B1/bg unknown
- 1994-10-20 BG BG99639/95A patent/BG61306B1/bg unknown
- 1994-12-07 LU LU88567A patent/LU88567A1/fr unknown
- 1994-12-08 DK DK140694A patent/DK140694A/da not_active Application Discontinuation
- 1994-12-09 SE SE9404290A patent/SE9404290L/xx not_active Application Discontinuation
1995
- 1995-02-27 NO NO950758A patent/NO950758D0/no unknown
- 1995-02-27 SE SE9500718A patent/SE9500718L/xx not_active Application Discontinuation
- 1995-03-09 AU AU14737/95A patent/AU680099B2/en not_active Ceased
- 1995-03-24 FI FI951414A patent/FI103973B/fi active
- 1995-03-31 JP JP7075492A patent/JPH08134072A/ja active Pending
- 1995-04-26 SE SE9501544A patent/SE503077C2/sv not_active IP Right Cessation
- 1995-04-28 CN CN95104832A patent/CN1041934C/zh not_active Expired - Fee Related
- 1995-05-03 NO NO951725A patent/NO178499C/no not_active IP Right Cessation
- 1995-05-15 CN CN95104675A patent/CN1036592C/zh not_active Expired - Fee Related
- 1995-05-16 BG BG99640A patent/BG61190B1/bg unknown
- 1995-05-19 JP JP7121206A patent/JPH08157480A/ja active Pending
- 1995-06-08 FI FI952820A patent/FI96952C/fi active
- 1995-06-15 DK DK068595A patent/DK170569B1/da not_active IP Right Cessation
1996
- 1996-01-11 HK HK6996A patent/HK6996A/xx not_active IP Right Cessation
- 1996-01-30 UY UY24154A patent/UY24154A1/es unknown
- 1996-01-31 GR GR950300070T patent/GR950300070T1/el unknown
- 1996-02-15 GR GR960400402T patent/GR3019006T3/el unknown
- 1996-02-29 SE SE9600797A patent/SE504220C2/sv not_active IP Right Cessation
- 1996-04-22 FI FI961739A patent/FI104488B/fi active
- 1996-09-27 CY CY189596A patent/CY1895A/xx unknown
- 1996-12-12 GR GR960403146T patent/GR3022006T3/el unknown
1997
- 1997-02-14 AU AU14716/97A patent/AU681569B3/en not_active Revoked
- 1997-09-09 GR GR970402308T patent/GR3024666T3/el unknown
- 1997-11-19 SE SE9704244A patent/SE9704244D0/xx unknown
1998
- 1998-03-10 HK HK98101974A patent/HK1003245A1/xx not_active IP Right Cessation
- 1998-03-10 HK HK98101976A patent/HK1003222A1/xx not_active IP Right Cessation
- 1998-03-20 FI FI980630A patent/FI980630A/fi not_active Application Discontinuation
- 1998-03-20 FI FI980631A patent/FI980631A0/fi not_active Application Discontinuation
- 1998-06-24 HK HK98106523A patent/HK1007311A1/xx not_active IP Right Cessation
- 1998-12-23 FI FI982790A patent/FI982790A0/fi unknown

Also Published As

Publication number	Publication date
HK1003222A1 (en)	1998-10-16
FI980630A0 (fi)	1998-03-20
SE9501544L (sv)	1995-04-26
IL105966A0 (en)	1993-10-20
IL105966A (en)	1997-09-30
NO951725L (no)	1994-12-09
AP474A (en)	1996-03-06
FI952820A (fi)	1995-06-08
DE69301571D1 (de)	1996-03-28
ATE157981T1 (de)	1997-09-15
GB2287026A (en)	1995-09-06
SK153394A3 (en)	1995-05-10
SK278367B6 (en)	1997-01-08
EP0672670A1 (de)	1995-09-20
DE4345286A1 (de)	1995-09-21
JPH07507324A (ja)	1995-08-10
MA22907A1 (fr)	1993-12-31
NO950758L (no)	1994-12-09
DE4392664T1 (de)	1995-06-01
NO178499C (no)	1997-04-01
NO943093L (no)	1994-12-09
NL9320037A (nl)	1995-06-01
GR3019006T3 (en)	1996-05-31
KR950700914A (ko)	1995-02-20
FI980631A (fi)	1998-03-20
SK153294A3 (en)	1995-05-10
DK0644887T3 (da)	1997-06-02
AU681569B3 (en)	1997-08-28
FI103973B1 (fi)	1999-10-29
GB9508496D0 (en)	1995-06-14
BG60999B1 (en)	1996-08-30
NO943093D0 (no)	1994-08-22
GR3024666T3 (en)	1997-12-31
CS202194A3 (cs)	1994-12-15
BG99640A (bg)	1996-02-28
CZ54495A3 (en)	1997-08-13
CA2117538A1 (en)	1993-12-23
CN1095069A (zh)	1994-11-16
AP473A (en)	1996-03-06
EP0747383A3 (de)	1996-12-18
DK0672669T3 (da)	1997-12-22
AP471A (en)	1996-03-06
GB2287025B (en)	1997-02-26
JPH08157480A (ja)	1996-06-18
HU9402405D0 (en)	1994-10-28
SI9300296B (sl)	1998-06-30
DK170569B1 (da)	1995-10-23
SK278561B6 (en)	1997-10-08
PT101711A (pt)	1995-12-29
NO951725D0 (no)	1995-05-03
BG99131A (bg)	1995-08-28
HK1003245A1 (en)	1998-10-16
FI96952C (fi)	1998-05-20
DE69301571T2 (de)	1996-07-18
EP0801069A1 (de)	1997-10-15
GB9508497D0 (en)	1995-06-14
DE69313869T2 (de)	1998-01-29
CZ125495A3 (en)	1996-06-12
BG99639A (bg)	1996-02-28
FI980630A (fi)	1998-03-20
AU4342793A (en)	1994-01-04
SE9404290D0 (sv)	1994-12-09
PT101710A (pt)	1995-12-29
SK278520B6 (en)	1997-08-06
SE9600797D0 (sv)	1996-02-29
GR950300070T1 (en)	1996-01-31
FI944031A (fi)	1994-10-24
SE504220C2 (sv)	1996-12-09
GR3022006T3 (en)	1997-03-31
EP0644887A1 (de)	1995-03-29
CN1112928A (zh)	1995-12-06
HUT68775A (en)	1995-07-28
NO178499B (no)	1996-01-02
KR0162264B1 (ko)	1998-12-01
UY24154A1 (es)	1996-07-23
AP9300537A0 (en)	1993-07-31
SE9500718D0 (sv)	1995-02-27
GB2287025A (en)	1995-09-06
ES2106615T3 (es)	1997-11-01
ES2080710T1 (es)	1996-02-16
GB2287026B (en)	1995-11-01
CY1895A (en)	1996-09-27
AU680099B2 (en)	1997-07-17
FI961739A0 (fi)	1996-04-22
SI9300296A (en)	1993-12-31
EP0747383A2 (de)	1996-12-11
HU9500610D0 (en)	1995-04-28
AU1786595A (en)	1995-07-06
RO111192B1 (ro)	1996-07-30
RU2081121C1 (ru)	1997-06-10
JPH08134072A (ja)	1996-05-28
HK6996A (en)	1996-01-19
FI951414A (fi)	1995-03-24
WO1993025557A1 (en)	1993-12-23
DK0672670T3 (da)	1996-03-25
CZ19396A3 (en)	1997-08-13
BG61306B1 (en)	1997-05-30
ES2080710T3 (es)	1996-05-16
EP0672670B1 (de)	1996-02-14
EP0699682A1 (de)	1996-03-06
BG61190B1 (bg)	1997-02-28
CZ267694A3 (en)	1997-08-13
LU88567A1 (fr)	1995-06-01
FI982790A (fi)	1998-12-23
EP0644887B1 (de)	1996-12-11
CN1036592C (zh)	1997-12-03
FI980631A0 (fi)	1998-03-20
CZ281102B6 (cs)	1996-06-12
CZ267594A3 (en)	1997-08-13
DE69306574D1 (de)	1997-01-23
EP0672669A1 (de)	1995-09-20
AU1473795A (en)	1995-06-22
SE9501544D0 (sv)	1995-04-26
SE9600797L (sv)	1996-02-29
FI952820A0 (fi)	1995-06-08
SE9404290L (sv)	1995-01-16
CN1113244A (zh)	1995-12-13
HU9501214D0 (en)	1995-06-28
FI982790A0 (fi)	1998-12-23
ATE146180T1 (de)	1996-12-15
HUT69374A (en)	1995-09-28
DE4345311C1 (de)	1996-02-01
FI96952B (fi)	1996-06-14
AU665159B2 (en)	1995-12-14
CN1037967C (zh)	1998-04-08
DE69306574T2 (de)	1997-04-30
ATE134192T1 (de)	1996-02-15
MX9303441A (es)	1994-03-31
DK140694A (da)	1994-12-08
AU1471697A (en)	1997-05-22
HK1007311A1 (en)	1999-04-09
SK99494A3 (en)	1995-04-12
RU95112522A (ru)	1997-02-10
CA2160768A1 (en)	1993-12-12
NO950758D0 (no)	1995-02-27
MY131501A (en)	2007-08-30
FI944031A0 (fi)	1994-09-02
FI961739A (fi)	1996-04-22
RO111193B1 (ro)	1996-07-30
FI951414A0 (fi)	1995-03-24
FI103973B (fi)	1999-10-29
EP0806426A1 (de)	1997-11-12
FI104488B (fi)	2000-02-15
EP0672669B1 (de)	1997-09-10
RO111191B1 (ro)	1996-07-30
HU212583B (en)	1996-08-29
DK68595A (da)	1995-06-15
SE9704244D0 (sv)	1997-11-19
SE9500718L (sv)	1995-02-27
CN1041934C (zh)	1999-02-03
ES2095059T3 (es)	1997-02-01
SE503077C2 (sv)	1996-03-18

Legal Events

Date	Code	Title	Description
1998-10-08	8364	No opposition during term of opposition
2005-04-07	8339	Ceased/non-payment of the annual fee

Publication	Publication Date	Title
DE69313869D1 (de)	1997-10-16	Verfahren zur Herstellung von Kalium Clavulanat
DE69323381D1 (de)	1999-03-18	Verfahren zur Herstellung von Mikrominiatur-Bauteilen
DE69317519T2 (de)	1998-11-26	Verfahren zur Herstellung von kristallinen Mikrohohlkugeln
DE59304719D1 (de)	1997-01-23	Verfahren zur Herstellung von Polysilazanen
DE69225702D1 (de)	1998-07-02	Verfahren zur Herstellung von kompakten Reinigungsmitteln
DE59303857D1 (de)	1996-10-24	Verfahren zur Herstellung von Dinitrotoluol
DE69320423T2 (de)	1999-02-18	Verfahren zur Herstellung von Polykarbonat
DE69307090D1 (de)	1997-02-13	Verfahren zur Herstellung von Reibungsmaterialen
DE3853962D1 (de)	1995-07-20	Verfahren zur Kristallisation von Kalium-Clavulanat.
DE69306016D1 (de)	1997-01-02	Verfahren zur Herstellung von Acrolein
DE69217346D1 (de)	1997-03-20	Verfahren zur Herstellung von Mikroleuchtkörpern
DE69213916D1 (de)	1996-10-24	Verfahren zur Herstellung von L-Ambrox
DE69428845T2 (de)	2002-04-04	Verfahren zur Herstellung von Sende-Empfängern
DE69310232D1 (de)	1997-06-05	Verfahren zur Herstellung von Organomonochlorsilan
DE69314142D1 (de)	1997-10-30	Verfahren zur Herstellung von Keramikteilen
DE59302489D1 (de)	1996-06-13	Verfahren zur Herstellung von Chlor-Fluor-Butenen
DE69321747D1 (de)	1998-12-03	Verfahren zur Herstellung von synthetischen Diamanten
DE59305108D1 (de)	1997-02-27	Verfahren zur Herstellung von Fluorkohlenwasserstoffen
DE69318666T2 (de)	1998-09-10	Verfahren zur Herstellung von optisch aktiven gamma-Hydroxyketonen
DE59305081D1 (de)	1997-02-20	Verfahren zur herstellung von hexafluorchlorbutenen
DE69233122D1 (de)	2003-08-14	Verfahren zur Herstellung von Hybridomen
DE69204818D1 (de)	1995-10-19	Verfahren zur Herstellung von Isobuten.
DE59304451D1 (de)	1996-12-19	Kontinuierliches Verfahren zur Herstellung von Polyorganosiloxanen
DE69410856T2 (de)	1998-12-17	Verfahren zur Herstellung von optisch aktiven Beta-hydroxy-ketonen
DE69403497D1 (de)	1997-07-10	Verfahren zur Herstellung von optisch aktivem 2-Aminopropanal