DE602004027171D1 - Verbindungen mit Aktivität an der 11Beta-Hydroxasteroiddehydrogenase - Google Patents
Verbindungen mit Aktivität an der 11Beta-HydroxasteroiddehydrogenaseInfo
- Publication number
- DE602004027171D1 DE602004027171D1 DE602004027171T DE602004027171T DE602004027171D1 DE 602004027171 D1 DE602004027171 D1 DE 602004027171D1 DE 602004027171 T DE602004027171 T DE 602004027171T DE 602004027171 T DE602004027171 T DE 602004027171T DE 602004027171 D1 DE602004027171 D1 DE 602004027171D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- activity
- hydroxasteroid
- 11beta
- dehydrogenase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000000694 effects Effects 0.000 title abstract 3
- 101710088194 Dehydrogenase Proteins 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000003834 intracellular effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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DKPA200300565 | 2003-04-11 | ||
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DKPA200300990 | 2003-06-30 | ||
DKPA200300988 | 2003-06-30 | ||
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DKPA200301910 | 2003-12-22 | ||
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EP (4) | EP2239012A3 (de) |
JP (2) | JP4629657B2 (de) |
AT (2) | ATE467616T1 (de) |
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2004
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- 2004-04-06 JP JP2006504355A patent/JP4629657B2/ja not_active Expired - Fee Related
- 2004-04-06 WO PCT/DK2004/000252 patent/WO2004089896A1/en not_active Application Discontinuation
- 2004-04-06 EP EP10164336A patent/EP2239012A3/de not_active Withdrawn
- 2004-04-06 DE DE602004027171T patent/DE602004027171D1/de not_active Expired - Lifetime
- 2004-04-06 EP EP04725888A patent/EP1618090A1/de not_active Withdrawn
- 2004-04-06 EP EP07102177A patent/EP1787982B1/de not_active Expired - Lifetime
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- 2004-04-06 AT AT04725891T patent/ATE482747T1/de not_active IP Right Cessation
- 2004-04-06 EP EP04725891A patent/EP1615698B1/de not_active Expired - Lifetime
- 2004-04-06 JP JP2006504353A patent/JP2006522746A/ja active Pending
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2009
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EP1787982A2 (de) | 2007-05-23 |
US20090264414A1 (en) | 2009-10-22 |
JP2006522746A (ja) | 2006-10-05 |
JP4629657B2 (ja) | 2011-02-09 |
WO2004089896A1 (en) | 2004-10-21 |
EP1618090A1 (de) | 2006-01-25 |
EP1615698A2 (de) | 2006-01-18 |
JP2006522748A (ja) | 2006-10-05 |
WO2004089470A3 (en) | 2004-12-23 |
EP2239012A2 (de) | 2010-10-13 |
EP1787982A3 (de) | 2007-05-30 |
EP1787982B1 (de) | 2010-05-12 |
ATE467616T1 (de) | 2010-05-15 |
WO2004089470A2 (en) | 2004-10-21 |
EP2239012A3 (de) | 2011-06-15 |
EP1615698B1 (de) | 2010-09-29 |
ATE482747T1 (de) | 2010-10-15 |
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