DE3876039T2 - Verfahren zur herstellung von optisch aktiven verbindungen mit pyridin-kernen. - Google Patents
Verfahren zur herstellung von optisch aktiven verbindungen mit pyridin-kernen.Info
- Publication number
- DE3876039T2 DE3876039T2 DE8888112789T DE3876039T DE3876039T2 DE 3876039 T2 DE3876039 T2 DE 3876039T2 DE 8888112789 T DE8888112789 T DE 8888112789T DE 3876039 T DE3876039 T DE 3876039T DE 3876039 T2 DE3876039 T2 DE 3876039T2
- Authority
- DE
- Germany
- Prior art keywords
- optically active
- active connections
- producing optically
- cores
- pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62212674A JP2691986B2 (ja) | 1987-08-28 | 1987-08-28 | ピリジン骨格を有する光学活性化合物の製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3876039D1 DE3876039D1 (de) | 1992-12-24 |
DE3876039T2 true DE3876039T2 (de) | 1993-04-22 |
Family
ID=16626522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888112789T Expired - Fee Related DE3876039T2 (de) | 1987-08-28 | 1988-08-05 | Verfahren zur herstellung von optisch aktiven verbindungen mit pyridin-kernen. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4971909A (de) |
EP (1) | EP0304706B1 (de) |
JP (1) | JP2691986B2 (de) |
DE (1) | DE3876039T2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2578658B2 (ja) * | 1989-02-21 | 1997-02-05 | チッソ株式会社 | 光学活性化合物及びその製造法 |
JP2542941B2 (ja) * | 1990-02-02 | 1996-10-09 | チッソ株式会社 | 光学活性ヒドロキシラクトン類の製造方法 |
US5126268A (en) * | 1990-03-30 | 1992-06-30 | Eastman Kodak Company | Alcohol-ester sparation by reaction with acetate |
US5130252A (en) * | 1990-05-14 | 1992-07-14 | Synthetech, Inc. | Resolution of furopyridine enantiomers and synthetic precursors thereof |
KR100244728B1 (ko) * | 1992-08-31 | 2000-03-02 | 스즈키 타다오 | 광학활성 1,4-디히드로피리딘 화합물 및 그의 제조방법 |
AT401385B (de) * | 1994-03-30 | 1996-08-26 | Chemie Linz Gmbh | Enzymatische racematspaltung asymmetrischer alkohole mittels vinylestern mehrbasiger carbonsäuren |
DE4414273A1 (de) * | 1994-04-23 | 1995-10-26 | Chemie Linz Deutschland | Enzymatische Racematspaltung asymmetrischer Alkohole mittels Vinylestern mehrbasiger Carbonsäuren |
EP0725146A4 (de) * | 1994-07-18 | 1998-12-23 | Daicel Chem | Verfahren zur herstellung optischaktiver triazolverbindungen und methode zur razemisierung optischaktiver triazolverbindungen |
DE19809649A1 (de) * | 1998-03-06 | 1999-09-09 | Hoechst Marion Roussel De Gmbh | Verfahren zur enzymatischen Enantiomeren-Trennung von 3(R)- und 3(S)-Hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridin bzw. der Carbonsäureester |
MX2017013383A (es) | 2015-04-20 | 2017-12-07 | Tolero Pharmaceuticals Inc | Prediccion de respuesta a alvocidib mediante perfilado mitocondrial. |
KR102608921B1 (ko) | 2015-05-18 | 2023-12-01 | 스미토모 파마 온콜로지, 인크. | 생체 이용률이 증가된 알보시딥 프로드러그 |
MX2018001289A (es) | 2015-08-03 | 2018-04-30 | Tolero Pharmaceuticals Inc | Terapias de combinacion para el tratamiento del cancer. |
US11279694B2 (en) | 2016-11-18 | 2022-03-22 | Sumitomo Dainippon Pharma Oncology, Inc. | Alvocidib prodrugs and their use as protein kinase inhibitors |
WO2019055579A1 (en) | 2017-09-12 | 2019-03-21 | Tolero Pharmaceuticals, Inc. | TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR |
ES2910071T3 (es) | 2018-03-08 | 2022-05-11 | Incyte Corp | Compuestos de aminopirazina diol como inhibidores de PI3K-Y |
WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
MX2021006544A (es) | 2018-12-04 | 2021-07-07 | Sumitomo Pharma Oncology Inc | Inhibidores de cinasa dependiente de ciclina 9 (cdk9) y polimorfos de los mismos para uso como agentes para el tratamiento de cancer. |
WO2020191326A1 (en) | 2019-03-20 | 2020-09-24 | Sumitomo Dainippon Pharma Oncology, Inc. | Treatment of acute myeloid leukemia (aml) with venetoclax failure |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1215924A (en) * | 1983-07-27 | 1986-12-30 | David W. Bewick | Process for producing optically active aryloxypropionic acids and derivatives thereof useful as herbicides |
US4916074A (en) * | 1986-10-30 | 1990-04-10 | Chisso Corporation | Process for producing optically active compounds |
-
1987
- 1987-08-28 JP JP62212674A patent/JP2691986B2/ja not_active Expired - Lifetime
-
1988
- 1988-08-02 US US07/227,248 patent/US4971909A/en not_active Expired - Lifetime
- 1988-08-05 EP EP88112789A patent/EP0304706B1/de not_active Expired
- 1988-08-05 DE DE8888112789T patent/DE3876039T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3876039D1 (de) | 1992-12-24 |
EP0304706A3 (en) | 1990-07-04 |
EP0304706B1 (de) | 1992-11-19 |
JPS6460398A (en) | 1989-03-07 |
JP2691986B2 (ja) | 1997-12-17 |
US4971909A (en) | 1990-11-20 |
EP0304706A2 (de) | 1989-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |