DE3783327T2 - Verfahren zur herstellung von optisch aktiven verbindungen. - Google Patents

Verfahren zur herstellung von optisch aktiven verbindungen.

Info

Publication number
DE3783327T2
DE3783327T2 DE8787309625T DE3783327T DE3783327T2 DE 3783327 T2 DE3783327 T2 DE 3783327T2 DE 8787309625 T DE8787309625 T DE 8787309625T DE 3783327 T DE3783327 T DE 3783327T DE 3783327 T2 DE3783327 T2 DE 3783327T2
Authority
DE
Germany
Prior art keywords
optically active
active connections
producing optically
producing
connections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787309625T
Other languages
English (en)
Other versions
DE3783327D1 (de
Inventor
Naoyuki Yoshida
Hiroshi Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JNC Corp
Original Assignee
Chisso Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61256952A external-priority patent/JPH0755158B2/ja
Priority claimed from JP61263837A external-priority patent/JPH0755157B2/ja
Application filed by Chisso Corp filed Critical Chisso Corp
Application granted granted Critical
Publication of DE3783327D1 publication Critical patent/DE3783327D1/de
Publication of DE3783327T2 publication Critical patent/DE3783327T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K19/00—Liquid crystal materials
    • C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
    • C09K19/06—Non-steroidal liquid crystal compounds
    • C09K19/08—Non-steroidal liquid crystal compounds containing at least two non-condensed rings
    • C09K19/10—Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing at least two benzene rings
    • C09K19/12—Non-steroidal liquid crystal compounds containing at least two non-condensed rings containing at least two benzene rings at least two benzene rings directly linked, e.g. biphenyls
    • C09K19/126—Compounds containing at least one asymmetric carbon atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8787309625T 1986-10-30 1987-10-30 Verfahren zur herstellung von optisch aktiven verbindungen. Expired - Fee Related DE3783327T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61256952A JPH0755158B2 (ja) 1986-10-30 1986-10-30 光学活性エステルの製造法
JP61263837A JPH0755157B2 (ja) 1986-11-07 1986-11-07 生化学的手法による光学活性なアルコ−ルとエステルの製造法

Publications (2)

Publication Number Publication Date
DE3783327D1 DE3783327D1 (de) 1993-02-11
DE3783327T2 true DE3783327T2 (de) 1993-04-22

Family

ID=26542980

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787309625T Expired - Fee Related DE3783327T2 (de) 1986-10-30 1987-10-30 Verfahren zur herstellung von optisch aktiven verbindungen.

Country Status (3)

Country Link
US (1) US4916074A (de)
EP (1) EP0266217B1 (de)
DE (1) DE3783327T2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2691986B2 (ja) * 1987-08-28 1997-12-17 チッソ株式会社 ピリジン骨格を有する光学活性化合物の製造法
US4904409A (en) * 1987-10-09 1990-02-27 Chisso Corporation Optically active-1-(2-halogen-substituted-phenyl)-ethanol and its derivative
DE3743824C2 (de) * 1987-12-23 1997-03-06 Hoechst Ag Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung
US5106750A (en) * 1988-08-30 1992-04-21 G. D. Searle & Co. Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
DE68925947T2 (de) * 1988-12-09 1996-09-12 Chisso Corp Optisch wirksame Verbindungen und Verfahren zu deren Herstellung
JP2578658B2 (ja) * 1989-02-21 1997-02-05 チッソ株式会社 光学活性化合物及びその製造法
US5187094A (en) * 1989-09-06 1993-02-16 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Method for the preparation of optically active 3-hydroxypyrrolidine derivatives
JP2852545B2 (ja) * 1989-11-14 1999-02-03 チッソ株式会社 複数の不斉点を持つ光学活性化合物および製造法
JP2542941B2 (ja) * 1990-02-02 1996-10-09 チッソ株式会社 光学活性ヒドロキシラクトン類の製造方法
CA2039857A1 (en) * 1990-04-26 1991-10-27 Wilfred Po-Sum Shum Process for producing epoxyalcohols of high optical purity
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US5258516A (en) * 1990-12-20 1993-11-02 Nc State University Optically pure D,E ring intermediates useful for the synthesis of camptothecin and camptothecin analogs
US5315007A (en) * 1990-12-20 1994-05-24 North Carolina State University Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs
US5212317A (en) * 1990-12-20 1993-05-18 North Carolina State University Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs
US5264579A (en) * 1990-12-20 1993-11-23 North Carolina State University D ring intermediates for the synthesis of camptothecin and camptothecin analogs
EP0538693A3 (en) * 1991-10-23 1994-08-17 Squibb & Sons Inc Stereoselective preparation of halophenyl alcohols
US5986095A (en) * 1992-01-06 1999-11-16 E.R. Squibb & Sons, Inc. Enantioselective preparation of halophenyl alcohols and acylates
US5262571A (en) * 1992-03-20 1993-11-16 North Carolina State University Cycloalkyl-based chiral auxiliaries and method making the same
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
EP0577446A3 (de) * 1992-05-28 1995-04-05 Showa Shell Sekiyu Verfahren zur Herstellung von optisch-aktiven Halogen-enthaltenden Alkoholen.
US5420337A (en) * 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
AT401385B (de) * 1994-03-30 1996-08-26 Chemie Linz Gmbh Enzymatische racematspaltung asymmetrischer alkohole mittels vinylestern mehrbasiger carbonsäuren
AU2004245567B2 (en) 2003-06-03 2011-06-23 Oxford University Innovation Limited Nutritional supplements and therapeutic compositions comprising (R)-3-hydroxybutyrate derivatives
US7855291B2 (en) 2005-12-29 2010-12-21 Lexicon Pharmaceuticals, Inc. Process for the preparation of substituted phenylalanines
UA96936C2 (uk) * 2005-12-29 2011-12-26 Лексикон Фармасьютикалз, Инк. Поліциклічні похідні амінокислот і їх застосування
US7897763B2 (en) 2005-12-29 2011-03-01 Lexicon Pharmaceuticals, Inc. Process for the preparation of substituted phenylalanines
EP3318260B1 (de) * 2007-08-24 2020-09-23 Lexicon Pharmaceuticals, Inc. Verfahren zur herstellung von verbindungen auf basis von 4-phenyl-6-(2,2,2-trifluor-1-phenylethoxy)-pyrimidin
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
AU2013337308B2 (en) 2012-11-05 2018-06-21 Tdeltas Ketone bodies to protect tissues from damage by ionizing radiation
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
GB2515603B (en) 2013-03-14 2015-10-14 Isis Innovation Process for producing (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3108927A1 (de) * 1981-03-10 1982-09-23 Haarmann & Reimer Gmbh, 3450 Holzminden Verfahren zur enzymatischen herstellung von estern und laktonen
EP0064855B1 (de) * 1981-05-07 1986-09-17 Unilever Plc Behandlung von Fetten
DE3468433D1 (en) * 1983-05-19 1988-02-11 Asahi Denka Kogyo Kk Reaction method for transesterifying fats and oils

Also Published As

Publication number Publication date
US4916074A (en) 1990-04-10
DE3783327D1 (de) 1993-02-11
EP0266217A2 (de) 1988-05-04
EP0266217B1 (de) 1992-12-30
EP0266217A3 (en) 1989-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee