DE1920635C3 - 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole - Google Patents
2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazoleInfo
- Publication number
- DE1920635C3 DE1920635C3 DE1920635A DE1920635A DE1920635C3 DE 1920635 C3 DE1920635 C3 DE 1920635C3 DE 1920635 A DE1920635 A DE 1920635A DE 1920635 A DE1920635 A DE 1920635A DE 1920635 C3 DE1920635 C3 DE 1920635C3
- Authority
- DE
- Germany
- Prior art keywords
- nitro
- methyl
- imidazolyl
- benzimidazole
- melting point
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
- C07C209/325—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups reduction by other means than indicated in C07C209/34 or C07C209/36
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
- C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1920635A DE1920635C3 (de) | 1969-04-19 | 1969-04-19 | 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole |
CS2059A CS167896B2 (fr) | 1969-04-19 | 1970-03-27 | |
CH491970A CH546774A (de) | 1969-04-19 | 1970-04-02 | Verfahren zur herstellung von 2-(5-nitro-2-imidazolyl)benzimidazolen. |
CH1820172A CH546768A (de) | 1969-04-19 | 1970-04-02 | Verfahren zur herstellung von 2-(5-nitro-2-imidazolyl)benzimidazolen. |
ES70378368A ES378368A1 (es) | 1969-04-19 | 1970-04-08 | Procedimiento para la preparacion de 2 - (5-nitro-2-imida- zolil) - ben-cimidazoles. |
DK188570AA DK137758B (da) | 1969-04-19 | 1970-04-15 | Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-imidazolyl)-benzimidazoler eller salte deraf. |
AT351470A AT294075B (de) | 1969-04-19 | 1970-04-17 | Verfahren zur Herstellung von neuen 2-(5-Nitro-2-imidazolyl)-benzimidazolen und ihren Salzen |
SE05326/70A SE364962B (fr) | 1969-04-19 | 1970-04-17 | |
FI701070A FI52861C (fi) | 1969-04-19 | 1970-04-17 | Menetelmä antimikrobisesti vaikuttavien 2-(5-nitro-2-imidatsolyyli)-be ntsimidatsolien valmistamiseksi. |
ZA702577A ZA702577B (en) | 1969-04-19 | 1970-04-17 | 2-(5-nitro-2-imidazolyl)-benzimidazoles |
BE749102D BE749102A (fr) | 1969-04-19 | 1970-04-17 | 2-(5-nitro-2-imidazolyl)-benzimidazoles et leur procede de preparation |
NO01455/70A NO126624B (fr) | 1969-04-19 | 1970-04-17 | |
FR707013970A FR2042351B1 (fr) | 1969-04-19 | 1970-04-17 | |
GB1874370A GB1312056A (en) | 1969-04-19 | 1970-04-20 | 2-5,-nitro-2,-imidazolyl-benzimidazoles |
NL7005703A NL7005703A (fr) | 1969-04-19 | 1970-04-20 | |
JP45033734A JPS4914231B1 (fr) | 1969-04-19 | 1970-04-20 | |
US05/287,852 US4053472A (en) | 1969-04-19 | 1972-09-11 | 2-(5-nitro-2-imidazolyl)-benzimidazoles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1920635A DE1920635C3 (de) | 1969-04-19 | 1969-04-19 | 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole |
Publications (3)
Publication Number | Publication Date |
---|---|
DE1920635A1 DE1920635A1 (de) | 1970-10-29 |
DE1920635B2 DE1920635B2 (de) | 1978-11-02 |
DE1920635C3 true DE1920635C3 (de) | 1979-06-28 |
Family
ID=5732064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1920635A Expired DE1920635C3 (de) | 1969-04-19 | 1969-04-19 | 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS4914231B1 (fr) |
AT (1) | AT294075B (fr) |
BE (1) | BE749102A (fr) |
CH (2) | CH546768A (fr) |
CS (1) | CS167896B2 (fr) |
DE (1) | DE1920635C3 (fr) |
DK (1) | DK137758B (fr) |
ES (1) | ES378368A1 (fr) |
FI (1) | FI52861C (fr) |
FR (1) | FR2042351B1 (fr) |
GB (1) | GB1312056A (fr) |
NL (1) | NL7005703A (fr) |
NO (1) | NO126624B (fr) |
SE (1) | SE364962B (fr) |
ZA (1) | ZA702577B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4053472A (en) * | 1969-04-19 | 1977-10-11 | Schering Aktiengesellschaft | 2-(5-nitro-2-imidazolyl)-benzimidazoles |
IT1043840B (it) * | 1971-05-08 | 1980-02-29 | Poli Ind Chimica Spa | Pirimidine 2 5 disostituite e processo per la loro preparazione |
US3996238A (en) * | 1972-02-08 | 1976-12-07 | Ciba-Geigy Corporation | 4- or 5-Nitroimidazoles and processes for their manufacture |
BE795636A (fr) * | 1972-02-19 | 1973-08-20 | Schering Ag | Nitroimidazolylpyrimidines, et leur procede de preparation |
PT78358B (en) * | 1983-04-07 | 1986-05-30 | Smith Kline French Lab | Chemical process |
EP0711768B1 (fr) * | 1994-05-31 | 2002-02-13 | Mitsui Chemicals, Inc. | Derive de benzimidazol |
US5968933A (en) * | 1994-08-26 | 1999-10-19 | Auckland Division Cancer Society Of New Zealand Inc. | DNA-targeted alkylating agents |
-
1969
- 1969-04-19 DE DE1920635A patent/DE1920635C3/de not_active Expired
-
1970
- 1970-03-27 CS CS2059A patent/CS167896B2/cs unknown
- 1970-04-02 CH CH1820172A patent/CH546768A/xx not_active IP Right Cessation
- 1970-04-02 CH CH491970A patent/CH546774A/xx not_active IP Right Cessation
- 1970-04-08 ES ES70378368A patent/ES378368A1/es not_active Expired
- 1970-04-15 DK DK188570AA patent/DK137758B/da unknown
- 1970-04-17 NO NO01455/70A patent/NO126624B/no unknown
- 1970-04-17 AT AT351470A patent/AT294075B/de active
- 1970-04-17 FR FR707013970A patent/FR2042351B1/fr not_active Expired
- 1970-04-17 ZA ZA702577A patent/ZA702577B/xx unknown
- 1970-04-17 FI FI701070A patent/FI52861C/fi active
- 1970-04-17 SE SE05326/70A patent/SE364962B/xx unknown
- 1970-04-17 BE BE749102D patent/BE749102A/fr unknown
- 1970-04-20 GB GB1874370A patent/GB1312056A/en not_active Expired
- 1970-04-20 JP JP45033734A patent/JPS4914231B1/ja active Pending
- 1970-04-20 NL NL7005703A patent/NL7005703A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2042351B1 (fr) | 1973-07-13 |
CH546768A (de) | 1974-03-15 |
DK137758C (fr) | 1978-10-09 |
ES378368A1 (es) | 1972-06-16 |
DE1920635B2 (de) | 1978-11-02 |
FI52861C (fi) | 1977-12-12 |
BE749102A (fr) | 1970-10-19 |
CH546774A (de) | 1974-03-15 |
CS167896B2 (fr) | 1976-05-28 |
DK137758B (da) | 1978-05-01 |
ZA702577B (en) | 1971-01-27 |
NO126624B (fr) | 1973-03-05 |
JPS4914231B1 (fr) | 1974-04-05 |
AT294075B (de) | 1971-11-10 |
DE1920635A1 (de) | 1970-10-29 |
NL7005703A (fr) | 1970-10-21 |
FI52861B (fr) | 1977-08-31 |
SE364962B (fr) | 1974-03-11 |
GB1312056A (en) | 1973-04-04 |
FR2042351A1 (fr) | 1971-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C3 | Grant after two publication steps (3rd publication) | ||
8339 | Ceased/non-payment of the annual fee |