CY1111628T1 - Υποκατεστημενες ενωσεις δικυκλολακταμης - Google Patents

Υποκατεστημενες ενωσεις δικυκλολακταμης

Info

Publication number
CY1111628T1
CY1111628T1 CY20111100479T CY111100479T CY1111628T1 CY 1111628 T1 CY1111628 T1 CY 1111628T1 CY 20111100479 T CY20111100479 T CY 20111100479T CY 111100479 T CY111100479 T CY 111100479T CY 1111628 T1 CY1111628 T1 CY 1111628T1
Authority
CY
Cyprus
Prior art keywords
compounds
bicyclactam
substituted
compositions
formula
Prior art date
Application number
CY20111100479T
Other languages
English (en)
Inventor
Robert Lee Dow
Michael John Munchhof
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of CY1111628T1 publication Critical patent/CY1111628T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Η εφεύρεση παρέχει ενώσεις του τύπου (I) και φαρμακευτικώς αποδεκτό άλας αυτών, όπου R1, R2, R3, R4, R5a, R5b, R5c, R5d, Q, Α, Ζ και R7 είναι όπως περιγράφεται εδώ, συνθέσεις αυτών και χρήσεις αυτών.
CY20111100479T 2007-08-02 2011-05-17 Υποκατεστημενες ενωσεις δικυκλολακταμης CY1111628T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95350707P 2007-08-02 2007-08-02
EP08788942A EP2185567B1 (en) 2007-08-02 2008-07-22 Substituted bicyclolactam compounds

Publications (1)

Publication Number Publication Date
CY1111628T1 true CY1111628T1 (el) 2015-10-07

Family

ID=39926534

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100479T CY1111628T1 (el) 2007-08-02 2011-05-17 Υποκατεστημενες ενωσεις δικυκλολακταμης

Country Status (34)

Country Link
US (2) US20090036425A1 (el)
EP (1) EP2185567B1 (el)
JP (1) JP4629808B2 (el)
KR (1) KR20100032443A (el)
CN (1) CN101772504A (el)
AP (1) AP2010005163A0 (el)
AR (1) AR067780A1 (el)
AT (1) ATE502948T1 (el)
AU (1) AU2008281545B2 (el)
BR (1) BRPI0815067A2 (el)
CA (1) CA2695291C (el)
CL (1) CL2008002227A1 (el)
CO (1) CO6251365A2 (el)
CR (1) CR11223A (el)
CY (1) CY1111628T1 (el)
DE (1) DE602008005757D1 (el)
DK (1) DK2185567T3 (el)
DO (1) DOP2010000046A (el)
EA (1) EA201000050A1 (el)
EC (1) ECSP109932A (el)
ES (1) ES2361716T3 (el)
HN (1) HN2008001191A (el)
HR (1) HRP20110335T1 (el)
MA (1) MA31580B1 (el)
PA (1) PA8791601A1 (el)
PE (1) PE20090897A1 (el)
PL (1) PL2185567T3 (el)
PT (1) PT2185567E (el)
SI (1) SI2185567T1 (el)
TN (1) TN2010000053A1 (el)
TW (1) TWI356059B (el)
UA (1) UA94833C2 (el)
WO (1) WO2009016462A2 (el)
ZA (1) ZA201000255B (el)

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HN2008001191A (es) 2012-01-17
CL2008002227A1 (es) 2009-04-17
WO2009016462A3 (en) 2009-03-26
TN2010000053A1 (fr) 2011-09-26
PL2185567T3 (pl) 2011-07-29
CR11223A (es) 2010-02-04
TW200916471A (en) 2009-04-16
BRPI0815067A2 (pt) 2015-02-10
PT2185567E (pt) 2011-05-27
ES2361716T3 (es) 2011-06-21
AP2010005163A0 (en) 2010-02-28
ECSP109932A (es) 2010-03-31
CN101772504A (zh) 2010-07-07
ATE502948T1 (de) 2011-04-15
EP2185567A2 (en) 2010-05-19
AU2008281545A1 (en) 2009-02-05
JP4629808B2 (ja) 2011-02-09
UA94833C2 (en) 2011-06-10
US20090137551A1 (en) 2009-05-28
MA31580B1 (fr) 2010-08-02
PE20090897A1 (es) 2009-08-06
DOP2010000046A (es) 2010-03-31
ZA201000255B (en) 2011-03-30
CA2695291C (en) 2012-04-17
WO2009016462A2 (en) 2009-02-05
US20090036425A1 (en) 2009-02-05
KR20100032443A (ko) 2010-03-25
EP2185567B1 (en) 2011-03-23
CA2695291A1 (en) 2009-02-05
AR067780A1 (es) 2009-10-21
DE602008005757D1 (de) 2011-05-05
DK2185567T3 (da) 2011-05-16
SI2185567T1 (sl) 2011-06-30
TWI356059B (en) 2012-01-11
US7718645B2 (en) 2010-05-18
JP2010535190A (ja) 2010-11-18
HRP20110335T1 (hr) 2011-06-30
AU2008281545B2 (en) 2011-12-08
PA8791601A1 (es) 2009-12-16
EA201000050A1 (ru) 2010-08-30
CO6251365A2 (es) 2011-02-21

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