CS236753B2 - Processing of thieno (1,5) benzodiazepine derivatives - Google Patents
Processing of thieno (1,5) benzodiazepine derivatives Download PDFInfo
- Publication number
- CS236753B2 CS236753B2 CS757991A CS799175A CS236753B2 CS 236753 B2 CS236753 B2 CS 236753B2 CS 757991 A CS757991 A CS 757991A CS 799175 A CS799175 A CS 799175A CS 236753 B2 CS236753 B2 CS 236753B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- thieno
- benzodiazepine
- ethyl
- methyl
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB51240/74A GB1533235A (en) | 1974-11-26 | 1974-11-26 | Benzodiazepine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CS236753B2 true CS236753B2 (en) | 1985-05-15 |
Family
ID=10459213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS757991A CS236753B2 (en) | 1974-11-26 | 1975-11-26 | Processing of thieno (1,5) benzodiazepine derivatives |
Country Status (30)
Country | Link |
---|---|
JP (1) | JPS6044314B2 (de) |
AR (1) | AR221203A1 (de) |
AT (1) | AT351547B (de) |
AU (1) | AU506340B2 (de) |
BE (1) | BE835932A (de) |
BG (1) | BG29573A3 (de) |
CA (1) | CA1075687A (de) |
CH (2) | CH613455A5 (de) |
CS (1) | CS236753B2 (de) |
DD (1) | DD123343A5 (de) |
DE (1) | DE2552403C2 (de) |
DK (1) | DK146887C (de) |
ES (1) | ES443011A1 (de) |
FR (1) | FR2292479A1 (de) |
GB (1) | GB1533235A (de) |
HK (1) | HK58681A (de) |
HU (1) | HU172493B (de) |
IE (1) | IE42564B1 (de) |
IL (1) | IL48502A (de) |
KE (1) | KE3163A (de) |
MY (1) | MY8200149A (de) |
NL (1) | NL186088C (de) |
NZ (1) | NZ179335A (de) |
PH (2) | PH11669A (de) |
PL (1) | PL100135B1 (de) |
RO (1) | RO69912A (de) |
SE (2) | SE421209B (de) |
SU (2) | SU629879A3 (de) |
YU (1) | YU298375A (de) |
ZA (1) | ZA757344B (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL62792A (en) * | 1980-05-07 | 1985-02-28 | Byk Gulden Lomberg Chem Fab | Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them |
GB8819059D0 (en) * | 1988-08-11 | 1988-09-14 | Lilly Industries Ltd | Benzodiazepine compounds & their use as pharmaceuticals |
GB9009229D0 (en) | 1990-04-25 | 1990-06-20 | Lilly Industries Ltd | Pharmaceutical compounds |
NZ247703A (en) * | 1992-05-29 | 1995-07-26 | Lilly Industries Ltd | Thienobenzdiazepine derivatives and medicaments thereof |
CA2234641A1 (en) * | 1995-11-01 | 1997-05-09 | Merck & Co., Inc. | Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases |
US6043358A (en) | 1995-11-01 | 2000-03-28 | Merck & Co., Inc. | Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases |
HUP0003718A3 (en) | 1997-09-02 | 2002-11-28 | Welfide Corp | Fused thiophene derivatives, use thereof and pharmaceutical compositions containing them |
PL199016B1 (pl) * | 2002-06-20 | 2008-08-29 | Adamed Sp Z Oo | Sposób wytwarzania olanzapiny |
SI21270A (sl) | 2002-07-15 | 2004-02-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Kristalne oblike olanzapina in postopki za njihovo pripravo |
DE10301923B3 (de) * | 2003-01-17 | 2004-09-16 | Krka Tovarna Zdravil, D.D. | Verfahren und Zwischenprodukte zur Herstellung von Olanzapin |
AR047460A1 (es) * | 2004-01-27 | 2006-01-18 | Synthon Bv | Proceso para la fabricacion de acetato de 2-metil-4-(4-metil-1-piperazinil)-10h-tieno[2,3-b][1,5]benzodiazepina (acetato de olanzapina) |
AR048272A1 (es) | 2004-03-18 | 2006-04-12 | Lek Pharmaceuticals | Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales. |
CN1980710B (zh) * | 2004-06-30 | 2013-06-12 | 阿特西斯公司 | 作为5-羟色胺受体调节剂的取代的氮杂环庚烯衍生物 |
EP2292624A1 (de) | 2009-07-20 | 2011-03-09 | LEK Pharmaceuticals d.d. | Olanzapinreinigungsverfahren |
-
1974
- 1974-11-25 SU SU742191705A patent/SU629879A3/ru active
- 1974-11-26 GB GB51240/74A patent/GB1533235A/en not_active Expired
-
1975
- 1975-11-20 DK DK524175A patent/DK146887C/da active
- 1975-11-20 IL IL48502A patent/IL48502A/xx unknown
- 1975-11-20 CA CA240,082A patent/CA1075687A/en not_active Expired
- 1975-11-21 PH PH17788A patent/PH11669A/en unknown
- 1975-11-21 AU AU86858/75A patent/AU506340B2/en not_active Expired
- 1975-11-22 DE DE2552403A patent/DE2552403C2/de not_active Expired
- 1975-11-24 CH CH604478A patent/CH613455A5/xx not_active IP Right Cessation
- 1975-11-24 CH CH1517275A patent/CH613454A5/xx not_active IP Right Cessation
- 1975-11-24 ZA ZA757344A patent/ZA757344B/xx unknown
- 1975-11-24 SE SE7513185A patent/SE421209B/xx not_active IP Right Cessation
- 1975-11-24 NZ NZ179335A patent/NZ179335A/xx unknown
- 1975-11-25 AR AR261340A patent/AR221203A1/es active
- 1975-11-25 YU YU02983/75A patent/YU298375A/xx unknown
- 1975-11-25 DD DD189666A patent/DD123343A5/xx unknown
- 1975-11-25 FR FR7535900A patent/FR2292479A1/fr active Granted
- 1975-11-25 JP JP50141080A patent/JPS6044314B2/ja not_active Expired
- 1975-11-25 IE IE2565/75A patent/IE42564B1/en unknown
- 1975-11-25 RO RO7584018A patent/RO69912A/ro unknown
- 1975-11-25 BE BE6045266A patent/BE835932A/xx not_active IP Right Cessation
- 1975-11-26 HU HU75LI00000284A patent/HU172493B/hu unknown
- 1975-11-26 ES ES443011A patent/ES443011A1/es not_active Expired
- 1975-11-26 BG BG7531601A patent/BG29573A3/xx unknown
- 1975-11-26 AT AT898275A patent/AT351547B/de not_active IP Right Cessation
- 1975-11-26 PL PL1975184991A patent/PL100135B1/pl unknown
- 1975-11-26 CS CS757991A patent/CS236753B2/cs unknown
- 1975-11-26 NL NLAANVRAGE7513833,A patent/NL186088C/xx not_active IP Right Cessation
-
1976
- 1976-10-07 SU SU762406250A patent/SU626702A3/ru active
-
1977
- 1977-02-22 PH PH19480A patent/PH24534A/en unknown
-
1978
- 1978-11-27 SE SE7812194A patent/SE429045B/sv not_active IP Right Cessation
-
1981
- 1981-09-24 KE KE3163A patent/KE3163A/xx unknown
- 1981-11-26 HK HK586/81A patent/HK58681A/xx unknown
-
1982
- 1982-12-30 MY MY149/82A patent/MY8200149A/xx unknown
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