CS202069B2 - Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines - Google Patents

Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines Download PDF

Info

Publication number: CS202069B2
Authority: CS; Czechoslovakia
Prior art keywords: formula; hydrogen; iii; defined above; process according
Prior art date: 1976-06-15

Application number

CS773960A

Other languages

Czech (cs)

English (en)

Inventor

Philip D Hammen

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-06-15

Filing date

1977-06-15

Publication date

1980-12-31

1977-06-15 Application filed by Pfizer filed Critical Pfizer

1979-06-05 Priority to CS793864A priority Critical patent/CS202071B2/cs

1979-06-05 Priority to CS793863A priority patent/CS202070B2/cs

1980-12-31 Publication of CS202069B2 publication Critical patent/CS202069B2/cs

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CS773960A 1976-06-15 1977-06-15 Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines CS202069B2 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
CS793864A CS202071B2 (cs)	1976-06-15	1979-06-05	Způsob přípravy 2-(4-substituovaných piperazin-1-yl)-4-amino-6,7- -dimethoxychinazolinů
CS793863A CS202070B2 (cs)	1976-06-15	1979-06-05	Způsob přípravy 2-(4-substituovaných piperazin-1-yl)-4-amino-6,7- -dimethoxychinazolinů

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US69620176A	1976-06-15	1976-06-15

Publications (1)

Publication Number	Publication Date
CS202069B2 true CS202069B2 (en)	1980-12-31

Family

ID=24796111

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS773960A CS202069B2 (en)	1976-06-15	1977-06-15	Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines

Country Status (34)

Country	Link
JP (1)	JPS52153985A (sv)
AR (1)	AR218251A1 (sv)
AT (1)	AT356115B (sv)
BE (1)	BE855656A (sv)
BG (3)	BG35747A3 (sv)
CA (1)	CA1068698A (sv)
CH (3)	CH638203A5 (sv)
CS (1)	CS202069B2 (sv)
DD (1)	DD131021A5 (sv)
DE (1)	DE2725019A1 (sv)
DK (1)	DK146625C (sv)
EG (1)	EG12922A (sv)
ES (1)	ES459364A1 (sv)
FI (1)	FI66853C (sv)
FR (1)	FR2355015A1 (sv)
GB (1)	GB1548856A (sv)
GR (1)	GR72288B (sv)
HK (1)	HK31481A (sv)
HU (1)	HU177883B (sv)
IE (1)	IE45423B1 (sv)
IL (1)	IL52167A (sv)
LU (1)	LU77530A1 (sv)
MY (1)	MY8100270A (sv)
NL (1)	NL172543C (sv)
NO (1)	NO147838C (sv)
NZ (1)	NZ184168A (sv)
PH (1)	PH22196A (sv)
PL (3)	PL113012B1 (sv)
PT (1)	PT66617B (sv)
RO (3)	RO73050A (sv)
SE (2)	SE435380B (sv)
SU (2)	SU1033002A3 (sv)
YU (1)	YU40164B (sv)
ZA (1)	ZA773014B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3346675A1 (de) *	1983-12-23	1985-07-04	Beiersdorf Ag, 2000 Hamburg	Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) *	1985-12-04	1987-10-12	Gerot Pharmazeutika	Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) *	1992-08-31	2001-04-10	Khashayar Karimian	Methods of making ureas and guanidines, and intermediates therefor
IL112249A (en)	1994-01-25	2001-11-25	Warner Lambert Co	Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5654307A (en) *	1994-01-25	1997-08-05	Warner-Lambert Company	Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112248A0 (en)	1994-01-25	1995-03-30	Warner Lambert Co	Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) *	1996-02-02	1999-08-03	Nitromed, Inc.	Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3511836A (en)	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3669968A (en)	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines
JPS536156B2 (sv) *	1972-10-30	1978-03-04
US3935213A (en)	1973-12-05	1976-01-27	Pfizer Inc.	Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (sv) *	1974-03-25	1975-10-04

1977
- 1977-05-16 SE SE7705745A patent/SE435380B/sv not_active IP Right Cessation
- 1977-05-18 CA CA278,728A patent/CA1068698A/en not_active Expired
- 1977-05-20 GR GR53521A patent/GR72288B/el unknown
- 1977-05-20 ZA ZA00773014A patent/ZA773014B/xx unknown
- 1977-05-20 NZ NZ184168A patent/NZ184168A/xx unknown
- 1977-05-25 IL IL52167A patent/IL52167A/xx unknown
- 1977-05-27 YU YU1326/77A patent/YU40164B/xx unknown
- 1977-05-31 JP JP6391877A patent/JPS52153985A/ja active Granted
- 1977-05-31 PT PT66617A patent/PT66617B/pt unknown
- 1977-05-31 DE DE19772725019 patent/DE2725019A1/de active Pending
- 1977-05-31 NL NLAANVRAGE7705939,A patent/NL172543C/xx not_active IP Right Cessation
- 1977-06-01 ES ES459364A patent/ES459364A1/es not_active Expired
- 1977-06-01 AT AT386977A patent/AT356115B/de not_active IP Right Cessation
- 1977-06-01 NO NO771919A patent/NO147838C/no unknown
- 1977-06-01 CH CH673777A patent/CH638203A5/de not_active IP Right Cessation
- 1977-06-01 DK DK240877A patent/DK146625C/da not_active IP Right Cessation
- 1977-06-01 EG EG338/77A patent/EG12922A/xx active
- 1977-06-01 FI FI771741A patent/FI66853C/fi not_active IP Right Cessation
- 1977-06-02 AR AR267927A patent/AR218251A1/es active
- 1977-06-03 BG BG8257395A patent/BG35747A3/xx unknown
- 1977-06-03 BG BG7736493A patent/BG35594A3/xx unknown
- 1977-06-03 BG BG8257396A patent/BG35748A3/xx unknown
- 1977-06-13 LU LU77530A patent/LU77530A1/xx unknown
- 1977-06-14 IE IE1212/77A patent/IE45423B1/en not_active IP Right Cessation
- 1977-06-14 RO RO7790683A patent/RO73050A/ro unknown
- 1977-06-14 FR FR7718206A patent/FR2355015A1/fr active Granted
- 1977-06-14 HU HU77PI578A patent/HU177883B/hu not_active IP Right Cessation
- 1977-06-14 RO RO7798088A patent/RO77330A/ro unknown
- 1977-06-14 SU SU772497901A patent/SU1033002A3/ru active
- 1977-06-14 GB GB24841/77A patent/GB1548856A/en not_active Expired
- 1977-06-14 BE BE178416A patent/BE855656A/xx not_active IP Right Cessation
- 1977-06-14 RO RO7798087A patent/RO77308A/ro unknown
- 1977-06-15 PL PL1977211797A patent/PL113012B1/pl unknown
- 1977-06-15 PL PL1977211798A patent/PL111221B1/pl unknown
- 1977-06-15 CS CS773960A patent/CS202069B2/cs unknown
- 1977-06-15 DD DD7700199502A patent/DD131021A5/xx unknown
- 1977-06-15 PL PL1977198874A patent/PL105558B1/pl unknown
1978
- 1978-01-03 PH PH20606A patent/PH22196A/en unknown
- 1978-06-28 SU SU782630798A patent/SU946402A3/ru active
1981
- 1981-07-02 HK HK314/81A patent/HK31481A/xx unknown
- 1981-12-16 SE SE8107554A patent/SE450120B/sv not_active IP Right Cessation
- 1981-12-30 MY MY270/81A patent/MY8100270A/xx unknown
1982
- 1982-04-22 CH CH245782A patent/CH638517A5/de not_active IP Right Cessation
- 1982-04-22 CH CH245682A patent/CH638516A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
PL111221B1 (en)	1980-08-30
JPS52153985A (en)	1977-12-21
FR2355015B1 (sv)	1981-07-24
BG35748A3 (en)	1984-06-15
SE450120B (sv)	1987-06-09
NZ184168A (en)	1979-08-31
CH638517A5 (en)	1983-09-30
IL52167A0 (en)	1977-07-31
DK146625B (da)	1983-11-21
PH22196A (en)	1988-06-28
NO771919L (no)	1977-12-16
DK240877A (da)	1977-12-16
AR218251A1 (es)	1980-05-30
GR72288B (sv)	1983-10-17
CH638203A5 (en)	1983-09-15
NO147838C (no)	1983-06-22
BG35747A3 (en)	1984-06-15
PL198874A1 (pl)	1978-04-10
NL172543C (nl)	1983-09-16
SU946402A3 (ru)	1982-07-23
RO77330A (ro)	1981-06-22
ZA773014B (en)	1978-04-26
BG35594A3 (en)	1984-05-15
AU2558377A (en)	1978-09-07
DD131021A5 (de)	1978-05-24
SE435380B (sv)	1984-09-24
IE45423B1 (en)	1982-08-25
CH638516A5 (en)	1983-09-30
FR2355015A1 (fr)	1978-01-13
IL52167A (en)	1981-01-30
CA1068698A (en)	1979-12-25
IE45423L (en)	1977-12-15
NO147838B (no)	1983-03-14
HU177883B (en)	1982-01-28
YU40164B (en)	1985-08-31
RO77308A (ro)	1981-08-17
JPS5543465B2 (sv)	1980-11-06
NL172543B (nl)	1983-04-18
GB1548856A (en)	1979-07-18
EG12922A (en)	1980-03-31
PT66617B (en)	1978-10-27
AT356115B (de)	1980-04-10
PL105558B1 (pl)	1979-10-31
PL113012B1 (en)	1980-11-29
BE855656A (fr)	1977-12-14
YU132677A (en)	1982-08-31
SE7705745L (sv)	1977-12-16
PT66617A (en)	1977-06-01
FI66853B (fi)	1984-08-31
ATA386977A (de)	1979-09-15
FI771741A (sv)	1977-12-16
RO73050A (ro)	1981-08-30
LU77530A1 (fr)	1979-03-26
DE2725019A1 (de)	1977-12-22
SU1033002A3 (ru)	1983-07-30
MY8100270A (en)	1981-12-31
SE8107554L (sv)	1981-12-16
ES459364A1 (es)	1978-03-16
HK31481A (en)	1981-07-10
DK146625C (da)	1984-06-04
FI66853C (fi)	1984-12-10
NL7705939A (nl)	1977-12-19

Similar Documents

Publication	Publication Date	Title
RU2096411C1 (ru)	1997-11-20	Производные бензимидазолона, смеси их изомеров или их кислотно-аддитивные соли в качестве антагониста рецептора 5-ht00i00a и 5-нт*002
US6566372B1 (en)	2003-05-20	Bicyclic androgen and progesterone receptor modulator compounds and methods
JP5285652B2 (ja)	2013-09-11	モルホリン誘導体の化学合成
JPH07215972A (ja)	1995-08-15	５−ｈｔ１ａ−拮抗活性を有する２，３−ジヒドロ−１，４−ベンゾジオキシン−５−イル−ピペラジン誘導体
JPH07188207A (ja)	1995-07-25	１−［２ｈ−１−ベンゾピラン−２−オン−８−イル］−ピペラジン誘導体
CS202069B2 (en)	1980-12-31	Method of preparing 2-/4-substituted piperazine-1-yl/-4-amino-6,7-dimethoxyquinazolines
EP1075473B1 (en)	2007-07-04	Process for making 1,3-disubstituted-4-oxocyclic ureas
RU1838309C (ru)	1993-08-30	Способ получени производных хиназолина или их формацевтически приемлемых кислотно-аддитивных солей
CZ294957B6 (cs)	2005-04-13	Způsob přípravy substituované imidazopyridinové sloučeniny
RU2295521C2 (ru)	2007-03-20	Фотохромные оксазиновые соединения и способы их производства
SU999967A3 (ru)	1983-02-23	Способ получени 6-N-замещенных 6-амино-3-пиридазинилгидразинов или их солей
CS202070B2 (cs)	1980-12-31	Způsob přípravy 2-(4-substituovaných piperazin-1-yl)-4-amino-6,7- -dimethoxychinazolinů
JPS6410514B2 (sv)	1989-02-22
US4282358A (en)	1981-08-04	Process for the production of substituted N-methylbenzoxazines
KR810000293B1 (ko)	1981-03-30	치환아미노 퀴나졸린 유도체의 제조방법
DK146510B (da)	1983-10-24	2-(4-(2-furoyl)piperazin-1-yl)-4-phthalimido-6,7-dimethoxyquinazolin til anvendelse som mellemprodukt ved fremstilling af 2-(4-(2-furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolin
DD297971A5 (de)	1992-01-30	Verfahren zur herstellung von chinazolinderivaten
JPS60233074A (ja)	1985-11-19	イミダゾ〔１，２−ａ〕ピリジン誘導体
JPH1112254A (ja)	1999-01-19	３−（３−ピリジルメチルアミノ）−３，４−ジヒドロ−２（１ｈ）−キナゾリノン誘導体及びその中間体の製造方法
JPS63112580A (ja)	1988-05-17	テトラヒドロピリド〔２，３−ｄ〕ピリミジン誘導体
GB2039885A (en)	1980-08-20	N-phenyl-N'-acyl-S- alkylisothiocarbamides
JPH0625161B2 (ja)	1994-04-06	２−アニリノ−１，６−ジヒドロ−６−オキソ−５−ピリミジンカルボン酸誘導体の製造法
MXPA00012725A (en)	2002-07-25	Chemical synthesis of morpholine derivatives
JPH0413356B2 (sv)	1992-03-09
JPH0332552B2 (sv)	1991-05-13