CN103550232A - Compound veterinary preparation for treating poultry enteritis type colibacillosis - Google Patents
Compound veterinary preparation for treating poultry enteritis type colibacillosis Download PDFInfo
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- CN103550232A CN103550232A CN201310545393.XA CN201310545393A CN103550232A CN 103550232 A CN103550232 A CN 103550232A CN 201310545393 A CN201310545393 A CN 201310545393A CN 103550232 A CN103550232 A CN 103550232A
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Abstract
The invention belongs to a composition for treating poultry enteritis type colibacillosis in veterinary medicines. The preparation consists of the following components in percentage by weight: 3.25 percent of neomycin sulfate, 0.81 percent of lactate TMP (trimethoprim lactate), 10 percent of glutamine, and 85.94 percent of auxiliary glucose, wherein neomycin sulfate, lactate TMP and glutamine are main drug components. The veterinary composition is used for treating poultry enteritis type colibacillosis. The processing process of the composition comprises the following steps: respectively crushing and screening each component, and accurately weighing according to the required proportion; mixing for 25 minutes; inspecting a semifinished product; subpackaging, packaging and inspecting the finished product. According to the usage method, the composition is drunk in a ratio of 1 percent, and four days are taken as a course of treatment. The composition has a remarkable curative effect on poultry enteritis type colibacillosis, is low in drug tolerance, safe and low-toxic, and has good popularization and application values.
Description
Technical field
The present invention relates to a kind of compound recipe veterinary drug preparation and preparation technology who treats fowl enteritis type colibacillosis.
Background technology
Colibacillosis is one of modal disease in poultry cultivation, and enteritis type colibacillosis is also to endanger one of the most serious disease.In veterinary clinic, birds infects enteritis type escherichia coli after being ill, often shows as diarrhoea, and appetite declines, feather is slightly random, feedstuff dyspepsia, poor growth, mortality increases gradually, and fertility performance reduces, and poultry farming is caused to more serious economic loss.And infect this after being ill, and can cause poultry resistance to reduce, be easy to secondary coccidiosis etc., aggravate disease, therapeutic effect is undesirable, and mortality rate raises, and sometimes up to more than 52%, economic loss is more serious.
Control enteritis type colibacillosis and infect, more conventional method is to use high-efficiency low-toxicity antimicrobial drug.Polygynax has that cost is lower, antibacterial action is strong, the residual advantage such as low of medicine, thereby is widely used in the treatment of enteritis type colibacillosis.But because it uses in a large number, produced certain drug resistance, the existing institute of curative effect declines at present.
Adopt lactic acid TMP and polygynax compatibility can play Synergistic, reduce drug resistance, reduce drug dose, reduce the effects such as side effect, add in addition intestinal mucosa renovation agent glutamine, can obviously improve intestinal mucosa cellular metabolism, promote the reparation of intestinal mucosa, strengthen mucosal immunity power and the resistance of poultry, prevention secondary infection.This combines not only treating both the principal and secondary aspects of a disease, strengthens therapeutic effect, prevention secondary infection, and also safe and effective, be difficult for producing drug resistance.For the consideration of these aspects, carried out the development of this compound medicine just.
Summary of the invention
Main purpose of the present invention is for compound recipe veterinary drug preparation and the preparation technology of a kind of sensitivity, the treatment enteritis type colibacillosis that efficient, drug resistance is low, easy to use are provided.
For achieving the above object, the present invention, through Multitest, has adopted following embodiment: a kind of compound recipe veterinary drug preparation of preventing and treating fowl enteritis type colibacillosis.Consisting of of bean preparation: polygynax 2.75-3.5%, lactic acid TMP 0. 69-0. 88%, glutamine 10%, other are glucose.
The invention has the beneficial effects as follows:
The white antibacterials polygynax of the present invention, Trimethoprim lactic acid TMP, intestinal mucosa renovation agent glutamine and adjuvant glucose form.Through a large amount of tests, said preparation has good therapeutic effect to fowl enteritis type colibacillosis, and can prevent secondary infection, be difficult for producing drug resistance, thereby can also reduce side effects of pharmaceutical drugs and drug residue by reducing drug dose, safe and effective, for aquaculture provides a kind of compound recipe veterinary drug preparation of control fowl enteritis type colibacillosis of efficient, stable, low toxicity.
The specific embodiment
Below in conjunction with an embodiment, the specific embodiment of the present invention is described in detail, and do not limit the scope of the invention to specific details.
embodiment 1
| ? | 100g |
| Polygynax | 12.75g (in effective content) |
| Lactic acid TMP | 0.69g (in effective content) |
| Glutamine | L 10g (in effective content) |
| Glucose | Add to 100g |
Preparation method and step: each composition is pulverized respectively, sieved, in required ratio, accurately weigh, mix 25min, semi-finished product quality inspection, packing, packing, finished product quality inspection and get final product.
In use, this preparation 100g is watered to 10L and is used for the treatment of clinical fowl enteritis type colibacillosis, connecting 4th is a course for the treatment of, and withdrawal time is 5.
The effective percentage of said preparation treatment fowl enteritis type colibacillosis is 62%, and cure rate is 50%, compares with 2.75% polygynax soluble powder, and effective percentage and cure rate exceed respectively 18%, 16%, and curative effect is undesirable.
embodiment 2
| ? | 100g |
| Polygynax | 3g (in effective content) |
| Lactic acid TMP | 0. 75g (in effective content) |
| Glutamine | 10g (in effective content) |
| Glucose | Add to 100g |
Preparation method and step: each composition is pulverized respectively, sieved, in required ratio, accurately weigh, mix 25min, semi-finished product quality inspection, packing, packing, finished product quality inspection and get final product.
In use, this preparation 100g is watered to 100L and is used for the treatment of clinical fowl enteritis type colibacillosis, being used in conjunction 4 is a course for the treatment of, and withdrawal time is 5.
The effective percentage of said preparation treatment fowl enteritis type colibacillosis is 82%, and cure rate is 71%, compares with 3% polygynax soluble powder, and effective percentage and cure rate exceed respectively 18%, 19%, and curative effect is medium.
embodiment 3
| ? | 100g |
| Polygynax | 3. 25g (in effective content) |
| Lactic acid TMP | 0. 8lg (in effective content) |
| Glutamine | 10g (in effective content) |
| Glucose | Add to 100g |
Preparation method and step: each composition is pulverized respectively, sieved, in required ratio, accurately weigh, mix 25min, semi-finished product quality inspection, packing, packing, finished product quality inspection and get final product.
In use, this preparation 100g is watered to 100L and is used for the treatment of clinical fowl enteritis type colibacillosis, being used in conjunction 4 is a course for the treatment of, and withdrawal time is 5.
The effective percentage of said preparation treatment fowl enteritis type colibacillosis is 93%, and cure rate is 82%, compares with 3. 25% polygynax soluble powders, and effective percentage and cure rate exceed respectively 22%, 20%, and curative effect is ideal.
embodiment 4
| ? | 100g |
| Polygynax | 3. 5g (in effective content) |
| Lactic acid TMP | 0. 88g (in effective content) |
| Glutamine | 10g (in effective content) |
| Glucose | Add to 100g |
Preparation method and step: each composition is pulverized respectively, sieved, in required ratio, accurately weigh, mix 25min, semi-finished product quality inspection, packing, packing, finished product quality inspection and get final product.
In use, this preparation 100g is watered to 100L and is used for the treatment of clinical fowl enteritis type colibacillosis, being used in conjunction 4 is a course for the treatment of, and withdrawal time is 5.
The effective percentage of said preparation treatment fowl enteritis type colibacillosis is 94%, cure rate is 82%, compare with 3. 5% polygynax soluble powders, effective percentage and cure rate exceed respectively 21%, 22%, curative effect is ideal, but very approaching with embodiment tri-combination curative effects, but cost increase, not as embodiment tri-combination ideals.
This combination adopts polygynax 3.25 %W/W, lactic acid TMP 0.81%W/W, glutamine 10%W/W, glucose 85. 94%, having efficient, safe, stable feature, is a kind of very good anti-fowl enteritis type colibacillosis compound preparation.
Above-described embodiment; comprise drug regimen, preparation technology and clinical verification; invention has been described; these descriptions are illustrative but not determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (2)
1. a compound recipe veterinary drug preparation for the treatment of fowl enteritis type colibacillosis, consisting of of said preparation: polygynax, lactic acid TMP, three kinds of main pharmaceutical compositions of glutamine, wherein polygynax 3.25%W/W, lactic acid TMP 0. 81%W/W, glutamine 10%W/W, described adjuvant is glucose, and adjuvant ratio is 85. 94%W/W.
2. treat according to claim 1 the preparation method of fowl enteritis type colibacillosis compound recipe veterinary drug preparation, it is characterized in that carrying out according to the following steps: polygynax, lactic acid TMP, glutamine and adjuvant are pulverized respectively, sieved, in required ratio, accurately weigh, mix 25min, make it mix homogeneously, packing and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310545393.XA CN103550232A (en) | 2013-11-07 | 2013-11-07 | Compound veterinary preparation for treating poultry enteritis type colibacillosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310545393.XA CN103550232A (en) | 2013-11-07 | 2013-11-07 | Compound veterinary preparation for treating poultry enteritis type colibacillosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103550232A true CN103550232A (en) | 2014-02-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310545393.XA Pending CN103550232A (en) | 2013-11-07 | 2013-11-07 | Compound veterinary preparation for treating poultry enteritis type colibacillosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103550232A (en) |
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2013
- 2013-11-07 CN CN201310545393.XA patent/CN103550232A/en active Pending
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140205 |
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| WD01 | Invention patent application deemed withdrawn after publication |