CN103432136A - Composition for treating salpingitis of chicken and preparation method of composition - Google Patents
Composition for treating salpingitis of chicken and preparation method of composition Download PDFInfo
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- CN103432136A CN103432136A CN2013103902205A CN201310390220A CN103432136A CN 103432136 A CN103432136 A CN 103432136A CN 2013103902205 A CN2013103902205 A CN 2013103902205A CN 201310390220 A CN201310390220 A CN 201310390220A CN 103432136 A CN103432136 A CN 103432136A
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- ofloxacin
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- dimetridazole
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Abstract
The invention discloses a composition for treating salpingitis of chicken and improving therapeutic effect and a preparation method of the composition. The composition is composed of the following components by weight percent: 15-30% of dimetronidazole, 5-15% of ofloxacin, 0.5-5% of vitamin E, and the balance of anhydrous glucose. Dimetronidazole and ofloxacin are combined in the composition disclosed by the invention, so that the resistance and killing range of the microorganisms infected by the chicken with salpingitis can be greatly improved, the source of the disease is eliminated and the therapeutic effect is improved through the effect of protecting the mucosa and promoting follicular development of vitamin E, the recovery of the laying rate is promoted, and the quality and number of the egg are improved.
Description
Technical field
The present invention relates to the veterinary drug technical field, relate to specifically a kind of composition and method of making the same that is used for the treatment of Chicken salpingitis.
Background technology
Chicken salpingitis is the common reproductive system disease of chicken, one or several mixed infection that cause of disease is antibacterial, mycoplasma, anaerobe and infusorian etc., main clinical manifestation is that laying hen egg yield descends, the situations such as husky preserved egg, little egg, soft-shelled egg appear, bring great loss to the raiser, and these eggs easily cause germ contamination, and affect food safety.
, due to antibacterials widely, make cause of disease produce stronger drug resistance now, add the cause of disease complexity of primary disease, culturist's treatment of often can't offeing medicine accurately, or, because medicine is insensitive or can not control in time infection, cause the reproductive system damage, and cause heavy losses to the culturist.
Summary of the invention
The present invention is in order to overcome weak point of the prior art, provides a kind of and can treat Chicken salpingitis, effective, reduces the mistaken diagnosis probability, improves the composition and method of making the same of cure rate.
The present invention is achieved through the following technical solutions:
A kind of compositions that is used for the treatment of Chicken salpingitis, is characterized in that, following raw material, consists of by weight percentage: dimetridazole 15～30%, and ofloxacin 5～15%, vitamin E 0.5～5%, surplus is anhydrous glucose.
A kind of above-mentioned preparation method that is used for the treatment of the compositions of Chicken salpingitis, is characterized in that, comprises the steps:
Get by weight percentage dimetridazole 15～30%, ofloxacin 5～15%, vitamin E 0.5～5%, surplus is anhydrous glucose; First ofloxacin is mixed with vitamin E, mixture mixes with dimetridazole again, and final mixture mixes with anhydrous glucose again, after mixing, obtains for treating the compositions of Chicken salpingitis.
Better consisting of wherein: dimetridazole 18～25% by weight percentage, ofloxacin 7～12%, and vitamin e1～4%, surplus is anhydrous glucose.
Best group becomes: dimetridazole 20% by weight percentage, ofloxacin 10%, vitamin E2 %, anhydrous glucose 68%.
The present invention has following technique effect:
Compositions of the present invention adopts two kinds of disease-resistant ultimate constituents: dimetridazole can be effectively to anaerobe resistant and trichomonacide, ofloxacin all has and suppresses or killing action gram negative bacteria, positive bacteria, mycoplasma, Papillary, can improve antimicrobial scope, effectively for causing salpingitic pathogen, vitamin E has the function that promotes reproduction, and tunica mucosa tubae uterinae is had to repair, and the normal development of promotion follicle, the three share, and can greatly improve salpingitic therapeutic effect; The present invention, by the rational combination collocation of several drugs, treats Chicken salpingitis, and the wide cure rate of antimicrobial scope is high, and can very large benefit be arranged to tunica mucosa tubae uterinae, follicle etc., thereby reduces the culturist because selecting the improper economic loss caused of medicine.
The specific embodiment
Below take and produce the 100kg compositions and the present invention is described in further detail as example.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
Embodiment 1
Take dimetridazole 15kg, ofloxacin 15kg, vitamin E 0.5kg, anhydrous glucose 69.5kg, ofloxacin is mixed with vitamin E 20 minutes, mixture mixes with dimetridazole 20 minutes again, finally is that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Embodiment 2
Take dimetridazole 30kg, ofloxacin 5kg, vitamin E 5kg, anhydrous glucose 60kg, mix ofloxacin 20 minutes with vitamin E, mixture mixes with dimetridazole 20 minutes again, finally be that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Embodiment 3
Take dimetridazole 18kg, ofloxacin 12kg, vitamin e1 kg, anhydrous glucose 69kg, mix ofloxacin 20 minutes with vitamin E, mixture mixes with dimetridazole 20 minutes again, finally be that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Embodiment 4
Take dimetridazole 25kg, ofloxacin 7kg, vitamin E 4kg, anhydrous glucose 64kg, mix ofloxacin 20 minutes with vitamin E, mixture mixes with dimetridazole 20 minutes again, finally be that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Embodiment 5
Take dimetridazole 19kg, ofloxacin 11kg, vitamin E 3kg, anhydrous glucose 68kg, mix ofloxacin 20 minutes with vitamin E, mixture mixes with dimetridazole 20 minutes again, finally be that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Embodiment 6
Take dimetridazole 20kg, ofloxacin 10kg, vitamin E2 kg, anhydrous glucose 68kg, mix ofloxacin 20 minutes with vitamin E, mixture mixes with dimetridazole 20 minutes again, finally be that anhydrous glucose fully mixes 1 hour, obtains for treating the compositions of Chicken salpingitis.
Clinical trial:
1. laboratory animal:
Choose at random 1000 of ill chickens, body weight is about the 2kg left and right.
2. Experimental agents
The compositions our unit development of the embodiment of the present invention 6 preparations;
The laboratory preparation of 20% dimetridazole powder (all the other 80% be anhydrous glucose) our unit;
The laboratory preparation of 10% ofloxacin soluble powder (all the other 90% be anhydrous glucose) our unit.
3. experimental technique:
Suffer from chicken by 1000 and be divided at random four groups by body weight, 250 every group.
The A group, for the blank group, does not give Drug therapy.
The B group is treated with 20% dimetridazole powder, usage: for oral administration: every chicken 0.1g 2 times on the one, is used in conjunction 4.
The C group is treated with 10% ofloxacin soluble powder, usage: for oral administration, every chicken 0.1g, 2 times on the one, be used in conjunction 4.
The D group is treated by the compositions of the embodiment of the present invention 6 preparations, usage: for oral administration: every chicken 0.1g 2 times on the one, is used in conjunction 4.
After treatment starts, every day entry is suffered from chicken egg number and good egg the rate ratio of total egg number (egg of quality better with)
Distribute, treat after 7 days and add up therapeutic effect.
Result of the test is as shown in the table.
4. conclusion:
The result of the test statistical analysis, the embodiment of the present invention 6 is used for the treatment of combination treatment group, 20% dimetridazole treated powder group and the 10% ofloxacin treated powder group of Chicken salpingitis and matched group difference extremely significantly (P<0.01).Curative effect of the present invention is better than other two kinds of medicines.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (6)
1. be used for the treatment of the compositions of Chicken salpingitis, it is characterized in that, formed by following raw material by weight percentage: dimetridazole 15～30%, ofloxacin 5～15%, vitamin E 0.5～5%, surplus is anhydrous glucose.
2. the compositions that is used for the treatment of Chicken salpingitis according to claim 1, it is characterized in that consisting of of each compositions in weight percentage: dimetridazole 18～25% by weight percentage, ofloxacin 7～12%, vitamin e1～4%, surplus is anhydrous glucose.
3. the compositions that is used for the treatment of Chicken salpingitis according to claim 1, it is characterized in that consisting of of each compositions in weight percentage: dimetridazole 20% by weight percentage, ofloxacin 10%, vitamin E2 %, anhydrous glucose 68%.
4. be used for the treatment of as claimed in claim 1 the preparation method of the compositions of Chicken salpingitis, it is characterized in that, comprise the steps: to get by weight percentage dimetridazole 15～30%, ofloxacin 5～15%, vitamin E 0.5～5%, surplus is anhydrous glucose; First ofloxacin is mixed with vitamin E, mixture mixes with dimetridazole again, and final mixture mixes with anhydrous glucose again, after mixing, obtains for treating the compositions of Chicken salpingitis.
5. the preparation method that is used for the treatment of the compositions of Chicken salpingitis according to claim 4, it is characterized in that consisting of of each compositions in weight percentage: dimetridazole 18～25% by weight percentage, ofloxacin 7～12%, vitamin e1～4%, surplus is anhydrous glucose.
6. the preparation method that is used for the treatment of the compositions of Chicken salpingitis according to claim 4, it is characterized in that consisting of of each compositions in weight percentage: dimetridazole 20% by weight percentage, ofloxacin 10%, vitamin E2 %, anhydrous glucose 68%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103902205A CN103432136A (en) | 2013-08-30 | 2013-08-30 | Composition for treating salpingitis of chicken and preparation method of composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013103902205A CN103432136A (en) | 2013-08-30 | 2013-08-30 | Composition for treating salpingitis of chicken and preparation method of composition |
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| Publication Number | Publication Date |
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| CN103432136A true CN103432136A (en) | 2013-12-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013103902205A Pending CN103432136A (en) | 2013-08-30 | 2013-08-30 | Composition for treating salpingitis of chicken and preparation method of composition |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103749984A (en) * | 2014-01-27 | 2014-04-30 | 山东新希望六和集团有限公司 | Feed for treating chicken salpingitis and preparation method thereof |
| CN105919942A (en) * | 2016-07-07 | 2016-09-07 | 杭州爱力迈动物药业有限公司 | Dimetridazole soluble powder and preparation method thereof |
| CN106074514A (en) * | 2016-08-31 | 2016-11-09 | 上海邦森生物科技有限公司 | A kind of water solublity dimetridazole pre-mixing agent and preparation method thereof |
-
2013
- 2013-08-30 CN CN2013103902205A patent/CN103432136A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103749984A (en) * | 2014-01-27 | 2014-04-30 | 山东新希望六和集团有限公司 | Feed for treating chicken salpingitis and preparation method thereof |
| CN103749984B (en) * | 2014-01-27 | 2015-03-25 | 山东新希望六和集团有限公司 | Feed for treating chicken salpingitis and preparation method thereof |
| CN105919942A (en) * | 2016-07-07 | 2016-09-07 | 杭州爱力迈动物药业有限公司 | Dimetridazole soluble powder and preparation method thereof |
| CN105919942B (en) * | 2016-07-07 | 2019-05-03 | 杭州爱力迈动物药业有限公司 | A kind of Dimetridazole soluble powder and preparation method thereof |
| CN106074514A (en) * | 2016-08-31 | 2016-11-09 | 上海邦森生物科技有限公司 | A kind of water solublity dimetridazole pre-mixing agent and preparation method thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131211 |
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| WD01 | Invention patent application deemed withdrawn after publication |