CN101450061A - Soluble powder for treating poultry bacterial infection - Google Patents
Soluble powder for treating poultry bacterial infection Download PDFInfo
- Publication number
- CN101450061A CN101450061A CNA2007101505658A CN200710150565A CN101450061A CN 101450061 A CN101450061 A CN 101450061A CN A2007101505658 A CNA2007101505658 A CN A2007101505658A CN 200710150565 A CN200710150565 A CN 200710150565A CN 101450061 A CN101450061 A CN 101450061A
- Authority
- CN
- China
- Prior art keywords
- bacterial infection
- florfenicol
- soluble powder
- adjuvant
- doxycycline hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a soluble powder for treating poultry bacterial infection, comprising florfenicol, doxycycline hyclate and auxiliary materials. The medicament of the invention has positive effect for treating poultry bacterial infection disease and can be suitable for popularization and application in the animal production. The invention combines the florfenicol with the doxycycline hyclate for using, can control pure bacterial infection, meanwhile also can treat mixed infection of the bacteria and mycoplasma, the invention has good oral administration absorption effect and high safety.
Description
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of soluble powder that is used for the treatment of poultry bacterial infection.
Background technology
Along with the expansion of intensive culture scale, the disease of each side such as the respiratory system disease of poultry, digestive system disease is more serious.Simultaneously because the abuse of antibiotics aspect poultry farming makes the problem of Resistant strain more and more serious.
Bacterial disease with fowl is an example, and the outburst of bacterial disease has had a strong impact on fowl weightening finish and efficiency of feed utilization, and laying rate is reduced, the carcass quality degradation, even cause a considerable amount of death, influenced the economic benefit of foster fowl.The pathogen of bacterial disease in poultry has a lot, has escherichia coli to cause, has pasteurellosis bacillus to cause, also has several bacteria mixed infections, and M ﹠ M does not wait.Often show as a series of symptoms such as spirit is depressed, loss of appetite, passage of loose stools clinically.Because the antibiotic medicine treatment that long-time use is same, drug resistance problem clinically is very serious.
Summary of the invention
Based on above-mentioned situation, the object of the present invention is to provide a kind of soluble powder that is used for the treatment of poultry bacterial infection.
The object of the present invention is achieved like this: represent to be respectively florfenicol 3.5%-4.5% with percentage by weight, doxycycline hydrochloride 1.5%-2.5%, adjuvant 93%-95%.
Described adjuvant comprises: anhydrous glucose, oral glucose etc. are preferably anhydrous glucose.
In order to obtain better effect, preferred ingredient is: florfenicol 4%, doxycycline hydrochloride 2%, adjuvant 94%.
The present invention can adopt the general process of industry, equipment preparation.The following method preparation of preferred employing comprises step:
Earlier florfenicol, doxycycline hydrochloride are pulverized with used adjuvant, pulverized back mistake 60 mesh sieves; The adjuvant of getting florfenicol, doxycycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly.
Florfenicol: belong to chloromycetin series antibiotics, antimicrobial spectrum and antibacterial activity are better than thiamphenicol, and multiple gram positive bacteria, gram negative bacteria and mycoplasma etc. are had stronger antibacterial activity.Still responsive to the drug-fast antibacterial of chloromycetin to florfenicol, be mainly used in the bacterial diseasees of poultry, also can be used for treating the microbial bovine mastitis of various cause of diseases.
Doxycycline hydrochloride: tetracycline antibiotics, antimicrobial spectrum is similar to other Tetracyclines, and external and antibacterial activity in vivo is all strong than oxytetracycline, tetracycline, mainly can be used for treating the mycoplasma, colibacillosis, Bacillus pasteurii disease of poultry etc.The for oral administration absorption rapidly is subjected to food effect less, the bioavailability height, and effectively the haemoconcentration length of holding time is strong, widely distributed to organizing penetration, easily enters in the cell.
In order to verify the curative effect of medicine of the present invention, get medicine of the present invention and do the clinical efficacy test at Tianjin Baodi county chicken house.Get the chicken that suffers from colibacillosis, this ill chicken group clinical symptoms mainly shows as the enteritis symptom, and depressed, the loss of appetite of spirit, diarrhoea use medicine of the present invention to treat, and add medicine 0.8g of the present invention in per 2 premium on currency, and logotype 5 days was a course of treatment.Most ofly after the course of treatment suffer from chicken and cured, above-mentioned clinical symptom disappearance or effectively alleviated, effective percentage all reaches more than 90%.
Beneficial effect: by clinical trial as can be seen, medicine of the present invention curative effect aspect treatment poultry bacterial infection disease is certain, is suitable for applying in herding is produced.The present invention fills a prescription and adopts doxycycline hydrochloride and two kinds of medication combined uses of florfenicol, also can treat the mixed infection of antibacterial and mycoplasma in the time of the control pure bacterial infection, and oral absorption is good, has higher safety.
The specific embodiment
Embodiment 1: earlier florfenicol 35g, doxycycline hydrochloride 15g and used adjuvant anhydrous glucose 950g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting florfenicol, doxycycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of soluble powder, wherein contain florfenicol 35g, doxycycline hydrochloride 15g.
Tri-Biocin.Be mainly used in the infection due to the domestic bird caused by sensitive bacteria, as colibacillosis, Bacillus pasteurii disease, salmonellosis etc.Usage and dosage: add medicine 0.7-1.2g of the present invention in per 2 premium on currency, logotype 3-5 days is a course of treatment.Careful usefulness when liver, renal failure.
Embodiment 2: earlier florfenicol 40g, doxycycline hydrochloride 20g and used adjuvant anhydrous glucose 940g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting florfenicol, doxycycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of soluble powder, wherein contain florfenicol 40g, doxycycline hydrochloride 20g.
Tri-Biocin.Be mainly used in the infection due to the domestic bird caused by sensitive bacteria, as colibacillosis, Bacillus pasteurii disease, salmonellosis etc.Usage and dosage: add medicine 0.5-1g of the present invention in per 2 premium on currency, logotype 3-5 days is a course of treatment.Careful usefulness when liver, renal failure.
Embodiment 3: earlier florfenicol 45g, doxycycline hydrochloride 25g and used adjuvant anhydrous glucose 930g are pulverized, pulverize back mistake 60 mesh sieves; The adjuvant of getting florfenicol, doxycycline hydrochloride and equivalent with equivalent progressively increase the dilution method dilution, mixes, mistake 60 order fine screens three times obtain mixture; With mixture and remaining adjuvant mix homogeneously, mixture is crossed 80 order fine screens three times, promptly get the about 1000g of soluble powder, wherein contain florfenicol 45g, doxycycline hydrochloride 25g.
Tri-Biocin.Be mainly used in the infection due to the domestic bird caused by sensitive bacteria, as colibacillosis, Bacillus pasteurii disease, salmonellosis etc.Usage and dosage: add medicine 0.4-0.9g of the present invention in per 2 premium on currency, logotype 3-5 days is a course of treatment.Careful usefulness when liver, renal failure.
Claims (3)
1, a kind of soluble powder that is used for the treatment of poultry bacterial infection is characterized in that the medicine that medicine of the present invention comprises is: florfenicol, doxycycline hydrochloride, adjuvant.
2, a kind of soluble powder that is used for the treatment of poultry bacterial infection according to claim 1, it is characterized in that: represent to be respectively florfenicol 3.5%-4.5% with percentage by weight, doxycycline hydrochloride 1.5%-2.5%, adjuvant 93%-95%, described adjuvant comprises: anhydrous glucose, oral glucose etc. are preferably anhydrous glucose.
3, a kind of soluble powder that is used for the treatment of poultry bacterial infection according to claim 1, it is characterized in that: preferred ingredient is: florfenicol 4%, doxycycline hydrochloride 2%, adjuvant 94%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505658A CN101450061A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating poultry bacterial infection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101505658A CN101450061A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating poultry bacterial infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101450061A true CN101450061A (en) | 2009-06-10 |
Family
ID=40732659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101505658A Pending CN101450061A (en) | 2007-11-29 | 2007-11-29 | Soluble powder for treating poultry bacterial infection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101450061A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008490A (en) * | 2010-12-07 | 2011-04-13 | 江西新天地药业有限公司 | Compound florfenicol injection for animal |
| CN104173374A (en) * | 2014-07-25 | 2014-12-03 | 邳州正康生物技术有限公司 | Formula and preparation method of florfenicol powder |
| CN105267977A (en) * | 2015-11-11 | 2016-01-27 | 郑州后羿制药有限公司 | Dissolvable doxycycline powder and preparation method thereof |
| CN106491574A (en) * | 2016-12-26 | 2017-03-15 | 浙江大飞龙动物保健品股份有限公司 | A kind of compound florfenicol powder and preparation method thereof |
| CN109700767A (en) * | 2019-01-29 | 2019-05-03 | 江西九信药业有限公司 | A kind of doxycycline hydrochloride soluble powder and preparation method thereof |
-
2007
- 2007-11-29 CN CNA2007101505658A patent/CN101450061A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008490A (en) * | 2010-12-07 | 2011-04-13 | 江西新天地药业有限公司 | Compound florfenicol injection for animal |
| CN102008490B (en) * | 2010-12-07 | 2012-06-27 | 江西新天地药业有限公司 | Compound florfenicol injection for animal |
| CN104173374A (en) * | 2014-07-25 | 2014-12-03 | 邳州正康生物技术有限公司 | Formula and preparation method of florfenicol powder |
| CN105267977A (en) * | 2015-11-11 | 2016-01-27 | 郑州后羿制药有限公司 | Dissolvable doxycycline powder and preparation method thereof |
| CN105267977B (en) * | 2015-11-11 | 2018-09-07 | 河南后羿实业集团有限公司 | A kind of Doxycycline soluble powder and preparation method thereof |
| CN106491574A (en) * | 2016-12-26 | 2017-03-15 | 浙江大飞龙动物保健品股份有限公司 | A kind of compound florfenicol powder and preparation method thereof |
| CN109700767A (en) * | 2019-01-29 | 2019-05-03 | 江西九信药业有限公司 | A kind of doxycycline hydrochloride soluble powder and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101468032A (en) | Soluble powder for treating respiratory illness of livestock and poultry | |
| CN101450067A (en) | Premixing agent for treating and preventing livestock and poultry respiratory disease | |
| CN101450061A (en) | Soluble powder for treating poultry bacterial infection | |
| CN101829082B (en) | Method for preparing veterinary injection of spectinomycin hydrochloride and lincomycin hydrochloride | |
| CN101450069A (en) | Soluble powder for treating poultry respiratory infection | |
| CN101468057A (en) | Compound Chinese medicine preparation for treating yellow-white dysentery of piglet | |
| CN102920719A (en) | Compound veterinary medicine preparation for treating avian enteritis type colibacillosis | |
| CN105963688A (en) | Powder for curing intestinal diseases of piglet and enhancing immunity and preparation method thereof | |
| CN110917141A (en) | Method for preparing florfenicol soluble powder medicament | |
| CN110917142A (en) | Florfenicol soluble powder medicine | |
| CN101669959A (en) | Medical composite for treating livestock and poultry intestinal canal diseases and preparation method and application thereof | |
| CN101966201A (en) | Compound norfloxacin nicotinic soluble powder and preparation method thereof | |
| CN101468030A (en) | Soluble powder for treating digestive system infection of livestock and poultry | |
| CN101301274B (en) | Compound mequindox soluble powder for animals and preparation thereof | |
| CN103830254A (en) | Soluble powder for treating respiratory diseases of livestock and poultry | |
| CN101468034A (en) | Soluble powder for treating mixed infection of fowl caused by bacteria and virus | |
| CN101468031A (en) | Premix for treating infection of livestock and poultry caused by sensitive bacteria | |
| CN104127429A (en) | Drinking water agent for preventing and treating livestock and poultry respiratory tract diseases and preparation method thereof | |
| CN101468010A (en) | Premix for preventing and treating infection of livestock and poultry caused by sensitive bacteria | |
| CN101468026A (en) | Premix for treating bacterial infection of livestock | |
| CN102784158B (en) | Preparation method of compound synergy tylosin tartrate for veterinary injection | |
| CN101450066A (en) | Soluble powder for treating poultry bacterial and mycoplasma infection | |
| CN101467998A (en) | Soluble powder for treating infection of domestic bird caused by sensitive bacteria | |
| CN105560446A (en) | Medicinal preparation for preventing and curing mycoplasmosis of livestock and improving non-specific immunity and preparing method of medicinal preparation | |
| CN101467970A (en) | Soluble powder for treating livestock and poultry infected by sensitive bacteria |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090610 |