CL2018000150A1 - Compuestos útiles como inmunomoduladores (divisional de solicitud 201600508) - Google Patents

Compuestos útiles como inmunomoduladores (divisional de solicitud 201600508)

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Publication number
CL2018000150A1
CL2018000150A1 CL2018000150A CL2018000150A CL2018000150A1 CL 2018000150 A1 CL2018000150 A1 CL 2018000150A1 CL 2018000150 A CL2018000150 A CL 2018000150A CL 2018000150 A CL2018000150 A CL 2018000150A CL 2018000150 A1 CL2018000150 A1 CL 2018000150A1
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CL
Chile
Prior art keywords
immunomodulators
divisional application
useful compounds
compounds
useful
Prior art date
Application number
CL2018000150A
Other languages
English (en)
Inventor
Louis S Chupak
Xiaofan Zheng
Original Assignee
Bristol Myers Squibb Co
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Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CL2018000150A1 publication Critical patent/CL2018000150A1/es

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    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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    • A61K31/396Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
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    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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Abstract

<p>LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS ÚTILES COMO INMUNOMODULADORES, ASÍ COMO TAMBIÉN A COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN TALES COMPUESTOS. ESTOS COMPUESTOS SON ÚTILES EN EL TRATAMIENTO, PREVENCIÓN O DISMINUCIÓN DEL PROGRESO DE ENFERMEDADES O TRASTORNOS VIROLÓGICOS Y CÁNCER.</p>
CL2018000150A 2013-09-04 2018-01-18 Compuestos útiles como inmunomoduladores (divisional de solicitud 201600508) CL2018000150A1 (es)

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US10745382B2 (en) 2015-10-15 2020-08-18 Bristol-Myers Squibb Company Compounds useful as immunomodulators
TW201718581A (zh) 2015-10-19 2017-06-01 英塞特公司 作為免疫調節劑之雜環化合物
TWI763641B (zh) * 2015-11-19 2022-05-11 美商英塞特公司 作為免疫調節劑之雜環化合物
CR20180323A (es) 2015-11-20 2018-08-06 Idorsia Pharmaceuticals Ltd Derivados de indol n-sustituídos como moduladores de los receptores de pge2
MA44075A (fr) * 2015-12-17 2021-05-19 Incyte Corp Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
MX2018007774A (es) 2015-12-22 2018-11-09 Incyte Corp Compuestos heterociclicos como inmunomoduladores.
EP3190103A1 (en) 2016-01-08 2017-07-12 Rijksuniversiteit Groningen Inhibitors of the pd-1/pd-l1 protein/protein interaction
CN109310677A (zh) 2016-04-07 2019-02-05 凯莫森特里克斯股份有限公司 通过联合施用ccr1拮抗剂与pd-1抑制剂或pd-l1拮抗剂降低肿瘤负荷
AR108396A1 (es) * 2016-05-06 2018-08-15 Incyte Corp Compuestos heterocíclicos como inmunomoduladores
WO2017202276A1 (zh) 2016-05-23 2017-11-30 中国医学科学院药物研究所 苯醚类衍生物、及其制法和药物组合物与用途
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