CL2008002478A1 - Compuestos derivados de n-fenil-5-(4 haloalcoxi)fenil) pirimidin-2-amino, inhibidores de c-kit y pdgfr; composicion farmaceutica; y su uso en el tratmiento de asma, dermatitis atopica, hipertension pulmonar o arterial, fibrosis renal, pulmonar o cardiaca, entre otras. - Google Patents
Compuestos derivados de n-fenil-5-(4 haloalcoxi)fenil) pirimidin-2-amino, inhibidores de c-kit y pdgfr; composicion farmaceutica; y su uso en el tratmiento de asma, dermatitis atopica, hipertension pulmonar o arterial, fibrosis renal, pulmonar o cardiaca, entre otras.Info
- Publication number
- CL2008002478A1 CL2008002478A1 CL2008002478A CL2008002478A CL2008002478A1 CL 2008002478 A1 CL2008002478 A1 CL 2008002478A1 CL 2008002478 A CL2008002478 A CL 2008002478A CL 2008002478 A CL2008002478 A CL 2008002478A CL 2008002478 A1 CL2008002478 A1 CL 2008002478A1
- Authority
- CL
- Chile
- Prior art keywords
- pulmonary
- phenyl
- asthma
- renal
- kit
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract
Compuestos derivados de pirimidin 2-amino, inhibidor de c-kit y pdgfr, composición farmacéutica que comprende dicho compuesto; y uso en el tratamiento de asma, dermatitis atófica, hipertensión pulmonar o arterial, fibrosis renal, pulmonar o cardiaca.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95726007P | 2007-08-22 | 2007-08-22 |
Publications (1)
Publication Number | Publication Date |
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CL2008002478A1 true CL2008002478A1 (es) | 2009-05-15 |
Family
ID=39929716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CL2008002478A CL2008002478A1 (es) | 2007-08-22 | 2008-08-22 | Compuestos derivados de n-fenil-5-(4 haloalcoxi)fenil) pirimidin-2-amino, inhibidores de c-kit y pdgfr; composicion farmaceutica; y su uso en el tratmiento de asma, dermatitis atopica, hipertension pulmonar o arterial, fibrosis renal, pulmonar o cardiaca, entre otras. |
Country Status (24)
Country | Link |
---|---|
US (1) | US8293757B2 (es) |
EP (1) | EP2190825B1 (es) |
JP (2) | JP5599312B2 (es) |
KR (2) | KR101218926B1 (es) |
CN (1) | CN101784530A (es) |
AR (1) | AR068014A1 (es) |
AU (1) | AU2008289037B2 (es) |
BR (1) | BRPI0815715A8 (es) |
CA (1) | CA2697081C (es) |
CL (1) | CL2008002478A1 (es) |
CO (1) | CO6260074A2 (es) |
CR (1) | CR11264A (es) |
EC (1) | ECSP10010044A (es) |
ES (1) | ES2477878T3 (es) |
MA (1) | MA31704B1 (es) |
MX (1) | MX2010002004A (es) |
PE (1) | PE20090992A1 (es) |
PL (1) | PL2190825T3 (es) |
PT (1) | PT2190825E (es) |
RU (1) | RU2455288C2 (es) |
TN (1) | TN2010000087A1 (es) |
TW (1) | TW200914023A (es) |
WO (1) | WO2009026276A1 (es) |
ZA (1) | ZA201001513B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101218926B1 (ko) * | 2007-08-22 | 2013-01-04 | 아이알엠 엘엘씨 | 키나제 억제제로서의 5-(4-(할로알콕시)페닐)피리미딘-2-아민 화합물 및 조성물 |
EA017392B1 (ru) | 2007-08-22 | 2012-12-28 | Айрм Ллк | Производные 2-гетероариламинопиримидина в качестве ингибиторов киназ |
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-
2008
- 2008-08-19 KR KR1020107006090A patent/KR101218926B1/ko not_active IP Right Cessation
- 2008-08-19 BR BRPI0815715A patent/BRPI0815715A8/pt not_active IP Right Cessation
- 2008-08-19 KR KR1020127024444A patent/KR20120107538A/ko not_active Application Discontinuation
- 2008-08-19 RU RU2010110640/04A patent/RU2455288C2/ru not_active IP Right Cessation
- 2008-08-19 MX MX2010002004A patent/MX2010002004A/es active IP Right Grant
- 2008-08-19 US US12/674,416 patent/US8293757B2/en not_active Expired - Fee Related
- 2008-08-19 JP JP2010521974A patent/JP5599312B2/ja not_active Expired - Fee Related
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- 2008-08-19 PL PL08798168T patent/PL2190825T3/pl unknown
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- 2008-08-19 PT PT87981684T patent/PT2190825E/pt unknown
- 2008-08-19 ES ES08798168.4T patent/ES2477878T3/es active Active
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- 2008-08-19 CA CA2697081A patent/CA2697081C/en not_active Expired - Fee Related
- 2008-08-19 WO PCT/US2008/073573 patent/WO2009026276A1/en active Application Filing
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- 2008-08-22 AR ARP080103671A patent/AR068014A1/es unknown
- 2008-08-22 PE PE2008001428A patent/PE20090992A1/es not_active Application Discontinuation
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- 2010-02-19 TN TNP2010000087A patent/TN2010000087A1/fr unknown
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Also Published As
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CA2697081C (en) | 2013-04-23 |
PT2190825E (pt) | 2014-07-16 |
MA31704B1 (fr) | 2010-09-01 |
ZA201001513B (en) | 2010-10-27 |
AU2008289037A1 (en) | 2009-02-26 |
PE20090992A1 (es) | 2009-08-14 |
RU2010110640A (ru) | 2011-09-27 |
PL2190825T3 (pl) | 2014-09-30 |
TW200914023A (en) | 2009-04-01 |
KR20100043288A (ko) | 2010-04-28 |
JP2010536867A (ja) | 2010-12-02 |
WO2009026276A1 (en) | 2009-02-26 |
JP5599312B2 (ja) | 2014-10-01 |
CO6260074A2 (es) | 2011-03-22 |
BRPI0815715A8 (pt) | 2017-07-04 |
CR11264A (es) | 2010-04-19 |
EP2190825B1 (en) | 2014-04-09 |
CN101784530A (zh) | 2010-07-21 |
US20110301175A1 (en) | 2011-12-08 |
JP2014177486A (ja) | 2014-09-25 |
US8293757B2 (en) | 2012-10-23 |
TN2010000087A1 (en) | 2011-09-26 |
RU2455288C2 (ru) | 2012-07-10 |
EP2190825A1 (en) | 2010-06-02 |
KR101218926B1 (ko) | 2013-01-04 |
MX2010002004A (es) | 2010-03-11 |
ES2477878T3 (es) | 2014-07-18 |
CA2697081A1 (en) | 2009-02-26 |
ECSP10010044A (es) | 2010-04-30 |
AR068014A1 (es) | 2009-10-28 |
AU2008289037B2 (en) | 2012-03-01 |
BRPI0815715A2 (pt) | 2017-06-13 |
KR20120107538A (ko) | 2012-10-02 |
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