BRPI0923045A2 - "derivados de 6-ciclo amino-2-tienil-3(piridin-4-il)imidazo{1,2-b]-piridazina e 6-ciclo amino-2-furanil-3-(piridin-4-il)imidazo[1,2-b]-piridazina,processo de preparação e aplicação terapêutica dos mesmos". - Google Patents
"derivados de 6-ciclo amino-2-tienil-3(piridin-4-il)imidazo{1,2-b]-piridazina e 6-ciclo amino-2-furanil-3-(piridin-4-il)imidazo[1,2-b]-piridazina,processo de preparação e aplicação terapêutica dos mesmos".Info
- Publication number
- BRPI0923045A2 BRPI0923045A2 BRPI0923045A BRPI0923045A BRPI0923045A2 BR PI0923045 A2 BRPI0923045 A2 BR PI0923045A2 BR PI0923045 A BRPI0923045 A BR PI0923045A BR PI0923045 A BRPI0923045 A BR PI0923045A BR PI0923045 A2 BRPI0923045 A2 BR PI0923045A2
- Authority
- BR
- Brazil
- Prior art keywords
- cycloamino
- pyridazine
- pyridin
- imidazo
- furanyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0807260A FR2940285A1 (fr) | 2008-12-19 | 2008-12-19 | Derives de 6-cycloamino-2-thienyl-3-(pyridin-4-yl)imidazo °1,2-b!-pyridazine et 6-cycloamino-2-furanyl-3- (pyridin-4-yl)imidazo°1,2-b!-pyridazine, leur preparation et leur application en therapeutique |
US13965408P | 2008-12-22 | 2008-12-22 | |
PCT/FR2009/052592 WO2010070237A1 (fr) | 2008-12-19 | 2009-12-17 | DÉRIVÉS DE 6-CYCLOAMINO-2-THIENYL-3-(PYRIDIN-4-YL)IMIDAZO[1,2-b]-PYRIDAZINE ET 6-CYCLOAMINO-2-FURANYL-3-(PYRIDIN-4-YL)IMIDAZO[1,2-b]-PYRIDAZINE, LEUR PRÉPARATION ET LEUR APPLICATION EN THÉRAPEUTIQUE |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0923045A2 true BRPI0923045A2 (pt) | 2015-12-15 |
Family
ID=40848280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0923045A BRPI0923045A2 (pt) | 2008-12-19 | 2009-12-17 | "derivados de 6-ciclo amino-2-tienil-3(piridin-4-il)imidazo{1,2-b]-piridazina e 6-ciclo amino-2-furanil-3-(piridin-4-il)imidazo[1,2-b]-piridazina,processo de preparação e aplicação terapêutica dos mesmos". |
Country Status (18)
Country | Link |
---|---|
US (1) | US20130190314A1 (pt) |
EP (1) | EP2398802A1 (pt) |
JP (1) | JP2012512852A (pt) |
KR (1) | KR20110108332A (pt) |
CN (1) | CN102256979A (pt) |
AR (1) | AR074795A1 (pt) |
AU (1) | AU2009329426A1 (pt) |
BR (1) | BRPI0923045A2 (pt) |
CA (1) | CA2747359A1 (pt) |
FR (1) | FR2940285A1 (pt) |
IL (1) | IL213581A0 (pt) |
MX (1) | MX2011006598A (pt) |
PA (1) | PA8854501A1 (pt) |
RU (1) | RU2011129828A (pt) |
SG (1) | SG172180A1 (pt) |
TW (1) | TW201028419A (pt) |
UY (1) | UY32348A (pt) |
WO (1) | WO2010070237A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2782601C (en) | 2009-12-18 | 2015-07-21 | Mitsubishi Tanabe Pharma Corporation | Novel antiplatelet agent |
US9556179B2 (en) | 2012-12-21 | 2017-01-31 | Bristol-Myers Squibb Company | Substituted imidazoles as casein kinase 1 D/E inhibitors |
CN104837844B (zh) * | 2012-12-21 | 2017-08-29 | 百时美施贵宝公司 | 作为酪蛋白激酶1 d/e抑制剂的吡唑取代的咪唑并哌嗪 |
AU2022367432A1 (en) | 2021-10-14 | 2024-05-02 | Incyte Corporation | Quinoline compounds as inhibitors of kras |
WO2023147015A1 (en) * | 2022-01-27 | 2023-08-03 | The Broad Institute, Inc. | Substituted heterocyclic csnk1 inhibitors |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001333A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
WO2005061498A1 (en) | 2003-12-11 | 2005-07-07 | Aventis Pharmaceuticals Inc. | Substituted 1h-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase i epsilon |
WO2005107760A1 (en) * | 2004-04-30 | 2005-11-17 | Irm Llc | Compounds and compositions as inducers of keratinocyte differentiation |
WO2006070943A1 (ja) * | 2004-12-28 | 2006-07-06 | Takeda Pharmaceutical Company Limited | 縮合イミダゾール化合物およびその用途 |
GB0515026D0 (en) * | 2005-07-21 | 2005-08-31 | Novartis Ag | Organic compounds |
DE102005042742A1 (de) * | 2005-09-02 | 2007-03-08 | Schering Ag | Substituierte Imidazo[1,2b]pyridazine als Kinase-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel |
US7750000B2 (en) * | 2005-09-02 | 2010-07-06 | Bayer Schering Pharma Ag | Substituted imidazo[1,2b]pyridazines as kinase inhibitors, their preparation and use as medicaments |
FR2918061B1 (fr) * | 2007-06-28 | 2010-10-22 | Sanofi Aventis | Derives de 6-cycloamino-3-(pyridin-4-yl)imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique. |
FR2918986B1 (fr) * | 2007-07-19 | 2009-09-04 | Sanofi Aventis Sa | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique |
-
2008
- 2008-12-19 FR FR0807260A patent/FR2940285A1/fr active Pending
-
2009
- 2009-12-17 KR KR1020117013962A patent/KR20110108332A/ko not_active Application Discontinuation
- 2009-12-17 RU RU2011129828/04A patent/RU2011129828A/ru not_active Application Discontinuation
- 2009-12-17 WO PCT/FR2009/052592 patent/WO2010070237A1/fr active Application Filing
- 2009-12-17 JP JP2011541566A patent/JP2012512852A/ja not_active Withdrawn
- 2009-12-17 MX MX2011006598A patent/MX2011006598A/es not_active Application Discontinuation
- 2009-12-17 PA PA20098854501A patent/PA8854501A1/es unknown
- 2009-12-17 EP EP09805728A patent/EP2398802A1/fr not_active Withdrawn
- 2009-12-17 US US13/141,006 patent/US20130190314A1/en not_active Abandoned
- 2009-12-17 BR BRPI0923045A patent/BRPI0923045A2/pt not_active Application Discontinuation
- 2009-12-17 SG SG2011043825A patent/SG172180A1/en unknown
- 2009-12-17 TW TW098143411A patent/TW201028419A/zh unknown
- 2009-12-17 CN CN2009801504972A patent/CN102256979A/zh active Pending
- 2009-12-17 CA CA2747359A patent/CA2747359A1/fr not_active Abandoned
- 2009-12-17 AU AU2009329426A patent/AU2009329426A1/en not_active Abandoned
- 2009-12-18 UY UY0001032348A patent/UY32348A/es not_active Application Discontinuation
- 2009-12-18 AR ARP090104972A patent/AR074795A1/es unknown
-
2011
- 2011-06-15 IL IL213581A patent/IL213581A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
PA8854501A1 (es) | 2010-07-27 |
KR20110108332A (ko) | 2011-10-05 |
FR2940285A1 (fr) | 2010-06-25 |
MX2011006598A (es) | 2011-10-12 |
SG172180A1 (en) | 2011-07-28 |
TW201028419A (en) | 2010-08-01 |
CN102256979A (zh) | 2011-11-23 |
IL213581A0 (en) | 2011-07-31 |
UY32348A (es) | 2010-07-30 |
AR074795A1 (es) | 2011-02-09 |
WO2010070237A1 (fr) | 2010-06-24 |
CA2747359A1 (fr) | 2010-06-24 |
EP2398802A1 (fr) | 2011-12-28 |
AU2009329426A1 (en) | 2011-07-07 |
JP2012512852A (ja) | 2012-06-07 |
RU2011129828A (ru) | 2013-01-27 |
US20130190314A1 (en) | 2013-07-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2918986B1 (fr) | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique | |
BRPI0917939A2 (pt) | derivados de 2-alquil-6-cicloamino-3-(piridin-4-il) imidazo[1,2-b]-piridazina, preparação dos mesmos e aplicação dos mesmos em terapia | |
ZA200909186B (en) | 6-cycloamino-3-(pyridin-4-yl)imidazo[1,2-b]pyridazine derivatives,preparation thereof and therapeutic use thereof | |
DK2069342T3 (da) | Derivater af 2-aryl-6-phenyl-imidazol[1,2-A]pyridiner, fremstilling og terapeutisk anvendelse deraf | |
WO2009108730A3 (en) | Forms of rifaximin and uses thereof | |
MX2010013020A (es) | Metodos y composiciones para trastornos del sueño y otros trastornos. | |
WO2008121687A3 (en) | Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors | |
IL208247A0 (en) | Polysubstituted derivatives of 6-heteroaryl-imidazo[1,2-a]pyridines, and preparation and therapeutic use thereof | |
MX2009006162A (es) | Compuestos y metodos para modulacion de cinasas, e indicaciones para ello. | |
NO20053920D0 (no) | Preparat for og behandling av demyelineringssykdommer og paralyse ved administrering av remyelineringsmidler. | |
ZA201005602B (en) | Imidazo [1,2-b]pyridazine derivatives for the treatment of c-met tyrosine kinase mediated disease | |
IL208248A0 (en) | Polysubstituted derivatives of 2-aryl-6-phenyl-imidizo[1,2-a]pyridines, and preparation and therapeutic use thereof | |
IL191160A (en) | Use of pyrido [3,2- b] pyrazine-6-yl urine urine for the preparation of drugs to treat diseases caused by the enzyme pi3k inhibition. | |
MX277822B (es) | Derivados de urea de tropano, su preparacion y su aplicacion terapeutica. | |
EA200800992A1 (ru) | 2-амино-7,8-дигидро-6н-пиридо[4,3-d]пиримидин-5-оны, способ их получения, способ терапии с их помощью, компонент композиции и композиция на их основе, 2,4-диоксопиперидиновые соединения для их получения | |
WO2009145456A3 (ko) | 헤테로사이클 유도체 | |
WO2008082887A3 (en) | Inhibitors of poly(adp-ribose)polymerase | |
BRPI0923045A2 (pt) | "derivados de 6-ciclo amino-2-tienil-3(piridin-4-il)imidazo{1,2-b]-piridazina e 6-ciclo amino-2-furanil-3-(piridin-4-il)imidazo[1,2-b]-piridazina,processo de preparação e aplicação terapêutica dos mesmos". | |
FR2925902B1 (fr) | DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | |
WO2008157563A3 (en) | Deuterium-enriched clopidogrel | |
DK2185561T3 (da) | Derivater af 1,2,3,4-tetrahydropyrrolo(1,2-a)pyrazin-6-carboxamid og 2,3,4,5-tetrahydroprrolo(1,2-a)-diazepin-7-carboxamid, fremstilling deraf og terapeutisk anvendelse deraf | |
BRPI0821992A2 (pt) | Derivados de n-heterocíclico-imidazo[1,2-a]piridina-2-carboxamida s, respectivo preparo e respectiva aplicação em terapêutica | |
BRPI0923182A2 (pt) | derivados de 6-cicloamino-2,3-di-piridinil-imidazo[1,2-b]piridazina, o respectivo preparo e a respectivo preparo e a respectiva aplicação terapêutica | |
IL198481A0 (en) | Pyrrole derivatives, preparation use of the same in therapy | |
BRPI0922760A2 (pt) | derivados de 6-ciclo amino -3-(1h-pirrolo [2,3-b] piridin -4-il) imidazo [1,2-b]- piridazina, o respectivo preparo e a respectiva aplicação em terapêutica |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |