FR2925902B1 - DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE - Google Patents

DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Info

Publication number
FR2925902B1
FR2925902B1 FR0800004A FR0800004A FR2925902B1 FR 2925902 B1 FR2925902 B1 FR 2925902B1 FR 0800004 A FR0800004 A FR 0800004A FR 0800004 A FR0800004 A FR 0800004A FR 2925902 B1 FR2925902 B1 FR 2925902B1
Authority
FR
France
Prior art keywords
imidazo
pyridine
preparation
therapeutic use
carboxamide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0800004A
Other languages
English (en)
Other versions
FR2925902A1 (fr
Inventor
Jean Francois Peyronel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39739369&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2925902(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0800004A priority Critical patent/FR2925902B1/fr
Priority to PA20088810101A priority patent/PA8810101A1/es
Priority to CL2008003927A priority patent/CL2008003927A1/es
Priority to ARP080105778A priority patent/AR070073A1/es
Priority to UY31588A priority patent/UY31588A1/es
Priority to PE2008002195A priority patent/PE20091182A1/es
Priority to EA201070817A priority patent/EA201070817A1/ru
Priority to JP2010541084A priority patent/JP2011508759A/ja
Priority to PCT/FR2008/001835 priority patent/WO2009112651A1/fr
Priority to MX2010007351A priority patent/MX2010007351A/es
Priority to BRPI0822223-1A priority patent/BRPI0822223A2/pt
Priority to KR1020107017147A priority patent/KR20100109941A/ko
Priority to EP08873283A priority patent/EP2225244A1/fr
Priority to CA2710797A priority patent/CA2710797A1/fr
Priority to TW097151675A priority patent/TW200932746A/zh
Priority to CN2008801277688A priority patent/CN101959886A/zh
Priority to AU2008352728A priority patent/AU2008352728A1/en
Publication of FR2925902A1 publication Critical patent/FR2925902A1/fr
Priority to IL206673A priority patent/IL206673A0/en
Priority to US12/828,372 priority patent/US20100317656A1/en
Priority to CO10080876A priority patent/CO6331307A2/es
Priority to MA33055A priority patent/MA32057B1/fr
Publication of FR2925902B1 publication Critical patent/FR2925902B1/fr
Application granted granted Critical
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR0800004A 2008-01-02 2008-01-02 DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE Expired - Fee Related FR2925902B1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0800004A FR2925902B1 (fr) 2008-01-02 2008-01-02 DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
PA20088810101A PA8810101A1 (es) 2008-01-02 2008-12-23 Derivados de imidazo[1,2-a]piridin-2-carboxamidas, su preparación y su aplicación en terapéutica
CL2008003927A CL2008003927A1 (es) 2008-01-02 2008-12-30 Compuestos derivados de imidazo[1,2-a]piridina-2-heterociclil-metanona, moduladores de los receptores nucleares nurr1; compuestos intermediarios; composicion farmaceutica; medicamento; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, psiquiatricas, inflamatorias, osteoporosis, cancer, entre otras.
ARP080105778A AR070073A1 (es) 2008-01-02 2008-12-30 Derivados de imidazo[1, 2 - a]piridin-2-carboxamidas, intermediarios para su preparacion, una composicion farmaceutica que los comprende y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades que implican a los receptores not.
UY31588A UY31588A1 (es) 2008-01-02 2008-12-30 Derivados de imidazo[1,2-a]piridin-2-carboxamidas, su preparacion y su aplicacion en terapéutica
PE2008002195A PE20091182A1 (es) 2008-01-02 2008-12-30 DERIVADOS DE IMIDAZO[1,2-a]PIRIDIN-2-CARBOXAMIDAS, SU PREPARACION Y SU APLICACION EN TERAPEUTICA
EP08873283A EP2225244A1 (fr) 2008-01-02 2008-12-31 Dérivés d'mtoazoý1,2-a¨pyridine-2-carboxamides, leur préparation et leur application en thérapeutique
CN2008801277688A CN101959886A (zh) 2008-01-02 2008-12-31 咪唑并[1,2-a]吡啶-2-甲酰胺衍生物、其制备方法及其治疗应用
PCT/FR2008/001835 WO2009112651A1 (fr) 2008-01-02 2008-12-31 Dérivés d'mtoazo[1,2-a]pyridine-2-carboxamides, leur préparation et leur application en thérapeutique
MX2010007351A MX2010007351A (es) 2008-01-02 2008-12-31 Derivados de imidazo[1,2-a]piridina-2-carboxamidas, su preparacion y su aplicacion en terapeutica.
BRPI0822223-1A BRPI0822223A2 (pt) 2008-01-02 2008-12-31 Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica
KR1020107017147A KR20100109941A (ko) 2008-01-02 2008-12-31 이미다조［１,２-ａ］피리딘-２-카르복스아미드 유도체, 그의 제법 및 치료제에서 그의 용도
EA201070817A EA201070817A1 (ru) 2008-01-02 2008-12-31 ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-α]ПИРИДИН-2-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ
CA2710797A CA2710797A1 (fr) 2008-01-02 2008-12-31 Derives d'imidazo[1,2-.alpha.]pyridine-2-carboxamides, leur preparation et leur application en therapeutique
TW097151675A TW200932746A (en) 2008-01-02 2008-12-31 Imidazo[1,2-α]pyridine-2-carboxamide derivatives, their preparation and their therapeutic application
JP2010541084A JP2011508759A (ja) 2008-01-02 2008-12-31 イミダゾ［１，２−ａ］ピリジン−２−カルボキサミド誘導体、この調製、およびこれの治療薬への応用
AU2008352728A AU2008352728A1 (en) 2008-01-02 2008-12-31 Imidazo[1,2-a]pyridine-2-carboxamide derivatives, preparation thereof and application thereof in therapeutics
IL206673A IL206673A0 (en) 2008-01-02 2010-06-28 Imidazo[1,2-a]pyridine-2-carboxamide derivatives, their preparation and their therapeutic application
US12/828,372 US20100317656A1 (en) 2008-01-02 2010-07-01 IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS
CO10080876A CO6331307A2 (es) 2008-01-02 2010-07-02 Derivados de imidazo[1,2alfa]piridin-2-carboxamidas su preparacion y su aplicacion en terapeutica
MA33055A MA32057B1 (fr) 2008-01-02 2010-08-02 Derives d'imtoazo [1,2-a] pyridine-2-carboxamides,leur préparation et leur application en thérapeutique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0800004A FR2925902B1 (fr) 2008-01-02 2008-01-02 DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publications (2)

Publication Number Publication Date
FR2925902A1 FR2925902A1 (fr) 2009-07-03
FR2925902B1 true FR2925902B1 (fr) 2011-01-07

Family

ID=39739369

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0800004A Expired - Fee Related FR2925902B1 (fr) 2008-01-02 2008-01-02 DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Country Status (21)

Country Link
US (1) US20100317656A1 (fr)
EP (1) EP2225244A1 (fr)
JP (1) JP2011508759A (fr)
KR (1) KR20100109941A (fr)
CN (1) CN101959886A (fr)
AR (1) AR070073A1 (fr)
AU (1) AU2008352728A1 (fr)
BR (1) BRPI0822223A2 (fr)
CA (1) CA2710797A1 (fr)
CL (1) CL2008003927A1 (fr)
CO (1) CO6331307A2 (fr)
EA (1) EA201070817A1 (fr)
FR (1) FR2925902B1 (fr)
IL (1) IL206673A0 (fr)
MA (1) MA32057B1 (fr)
MX (1) MX2010007351A (fr)
PA (1) PA8810101A1 (fr)
PE (1) PE20091182A1 (fr)
TW (1) TW200932746A (fr)
UY (1) UY31588A1 (fr)
WO (1) WO2009112651A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2925907B1 (fr) * 2008-01-02 2010-10-15 Sanofi Aventis DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
WO2012026766A2 (fr) * 2010-08-25 2012-03-01 (주)네오팜 Nouveau composé hétérocyclique, et composition pour traiter des maladies inflammatoires utilisant le même
ES2928084T3 (es) 2015-02-20 2022-11-15 Rigel Pharmaceuticals Inc Inhibidores de GDF-8
CN111108105B (zh) 2017-09-22 2023-03-31 朱比兰特埃皮帕德有限公司 作为pad抑制剂的杂环化合物
SG11202003463XA (en) 2017-10-18 2020-05-28 Jubilant Epipad LLC Imidazo-pyridine compounds as pad inhibitors
CA3080677A1 (fr) 2017-11-06 2019-05-09 Jubilant Prodel LLC Derives de pyrimidine utilises en tant qu'inhibiteurs de l'activation de pd1/pd-l1
CN107915752B (zh) * 2017-11-14 2018-09-18 牡丹江医学院 一种治疗白内障的药物及其制备方法
IL274762B2 (en) 2017-11-24 2023-10-01 Jubilant Episcribe Llc Novel heterocyclic compounds as PRMT5 inhibitors
SG11202008950PA (en) 2018-03-13 2020-10-29 Jubilant Prodel LLC Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827189D0 (en) * 1988-11-21 1988-12-29 Fujisawa Pharmaceutical Co 2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same
US5716964A (en) * 1989-12-04 1998-02-10 G.D. Searle & Co. Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
FR2696177B1 (fr) * 1992-09-28 1995-05-12 Synthelabo Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
GB0420519D0 (en) * 2004-09-15 2004-10-20 Novartis Ag Organic compounds
AU2008287421A1 (en) * 2007-08-10 2009-02-19 Glaxosmithkline Llc Nitrogen containing bicyclic chemical entities for treating viral infections
AU2008345225A1 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms

Also Published As

Publication number Publication date
CA2710797A1 (fr) 2009-09-17
PA8810101A1 (es) 2009-08-26
MX2010007351A (es) 2010-10-05
EP2225244A1 (fr) 2010-09-08
KR20100109941A (ko) 2010-10-11
JP2011508759A (ja) 2011-03-17
CN101959886A (zh) 2011-01-26
EA201070817A1 (ru) 2011-02-28
PE20091182A1 (es) 2009-08-31
UY31588A1 (es) 2009-08-03
CL2008003927A1 (es) 2010-02-12
AR070073A1 (es) 2010-03-10
TW200932746A (en) 2009-08-01
MA32057B1 (fr) 2011-02-01
IL206673A0 (en) 2010-12-30
AU2008352728A1 (en) 2009-09-17
BRPI0822223A2 (pt) 2015-06-23
US20100317656A1 (en) 2010-12-16
CO6331307A2 (es) 2011-10-20
FR2925902A1 (fr) 2009-07-03
WO2009112651A1 (fr) 2009-09-17

Similar Documents

Publication Publication Date Title
FR2918061B1 (fr) Derives de 6-cycloamino-3-(pyridin-4-yl)imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique.
FR2928922B1 (fr) Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928921B1 (fr) Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
FR2906250B1 (fr) Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
FR2918986B1 (fr) Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique
FR2928924B1 (fr) Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2911604B1 (fr) Derives de n-(heteroaryl-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
FR2915198B1 (fr) Derives de triazolopyridine-carboxamides et triazolopyridine -carboxamides, leur preparation et leur application en therapeutique.
FR2925902B1 (fr) DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2945534B1 (fr) DERIVES DE CYCLOPENTAL[c]PYRROLE-2-CARBOXYLATES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2915199B1 (fr) Derives de triazolopyridine-carboxamides et triazolopyrimidine-carboxamides, leur preparation et leur application en therapeutique.
FR2872813B1 (fr) Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
FR2933700B1 (fr) Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2866888B1 (fr) Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique
FR2915197B1 (fr) Derives de triazolopyridine-carboxamides, leur preparation et leur application therapeutique.
FR2945533B1 (fr) Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2920023B1 (fr) Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique
FR2917413B1 (fr) Derives de 7-alkynyl-1,8-naphthyridones, leur preparation et leur application en therapeutique
FR2925901B1 (fr) DERIVES DE N-HETEROCYCLIQUE-IMIDAZO°1,2-a!PYRIDINE-2- CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2955109B1 (fr) Derives de 5-oxo-5,8-dihydro-pyrido[2, 3-d]pyrimidine, leur preparation et leur application en therapeutique
FR2940284B1 (fr) Derives de 6-cycloamino-2,3-di-pyridinyl-imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique
FR2876692B1 (fr) Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique
FR2906251B1 (fr) Derives de pyrrolizine, indolizine et quinolizine, leur preparation et leur application en therapeutique
FR2892416B1 (fr) Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
FR2960876B1 (fr) Derives de 3,4-dihydropyrrolo[1,2-a]pyrazine-2,8(1h)-dicarboxamide leur preparation et leur application en therapeutique.

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20120928