BRPI0412257A - compostos para inflamação e usos imuno-relacionados - Google Patents

compostos para inflamação e usos imuno-relacionados

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Publication number
BRPI0412257A
BRPI0412257A BRPI0412257-7A BRPI0412257A BRPI0412257A BR PI0412257 A BRPI0412257 A BR PI0412257A BR PI0412257 A BRPI0412257 A BR PI0412257A BR PI0412257 A BRPI0412257 A BR PI0412257A
Authority
BR
Brazil
Prior art keywords
compounds
inflammation
immune related
related uses
clathrate
Prior art date
Application number
BRPI0412257-7A
Other languages
English (en)
Inventor
Yu Xie
Mats Holmqvist
Jerome Mahiou
Mitsunori Ono
Lijun Sun
Shoujun Chen
Shijie Zhang
Jun Jiang
Dinesh Chimmanamada
Chi-Yi Yu
Original Assignee
Synta Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp filed Critical Synta Pharmaceuticals Corp
Publication of BRPI0412257A publication Critical patent/BRPI0412257A/pt

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    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/66—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

"COMPOSTOS PARA INFLAMAçãO E USOS IMUNO-RELACIONADOS". A presente invenção refere-se a compostos de fórmula (I): ou um sal farmaceuticamente aceitável, solvato, clatrato ou pró-droga deste em que X, Y, A, Z, L e n são definidos aqui. Estes compostos são úteis como agentes imunossupressores e para tratar e prevenir condições inflamatórias e distúrbios imunes.
BRPI0412257-7A 2003-07-23 2004-07-22 compostos para inflamação e usos imuno-relacionados BRPI0412257A (pt)

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BRPI0412257-7A BRPI0412257A (pt) 2003-07-23 2004-07-22 compostos para inflamação e usos imuno-relacionados

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CN1826121A (zh) 2006-08-30
NO20060409L (no) 2006-04-04
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CN1826121B (zh) 2013-05-29
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EP2319516A1 (en) 2011-05-11
CA2533598C (en) 2012-09-11
CY1112214T1 (el) 2015-12-09
KR20060058092A (ko) 2006-05-29
KR101245062B1 (ko) 2013-03-19
US20150005320A9 (en) 2015-01-01
WO2005009539A2 (en) 2005-02-03
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IL173269A0 (en) 2006-06-11
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US20050107436A1 (en) 2005-05-19
ATE492278T1 (de) 2011-01-15
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ZA200601560B (en) 2008-04-30
US20140107134A1 (en) 2014-04-17
BRPI0412805A (pt) 2006-09-26
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