DE60325025D1 - Modulatoren des vanilloidrezeptors - Google Patents
Modulatoren des vanilloidrezeptorsInfo
- Publication number
- DE60325025D1 DE60325025D1 DE60325025T DE60325025T DE60325025D1 DE 60325025 D1 DE60325025 D1 DE 60325025D1 DE 60325025 T DE60325025 T DE 60325025T DE 60325025 T DE60325025 T DE 60325025T DE 60325025 D1 DE60325025 D1 DE 60325025D1
- Authority
- DE
- Germany
- Prior art keywords
- modulators
- vanilloid receptor
- vanilloid
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0203677A GB0203677D0 (en) | 2002-02-15 | 2002-02-15 | Novel compounds |
GB0203673A GB0203673D0 (en) | 2002-02-15 | 2002-02-15 | Novel compounds |
GB0203680A GB0203680D0 (en) | 2002-02-15 | 2002-02-15 | Novel compounds |
GB0209032A GB0209032D0 (en) | 2002-04-19 | 2002-04-19 | Novel compounds |
GB0209003A GB0209003D0 (en) | 2002-04-19 | 2002-04-19 | Novel compounds |
GB0209035A GB0209035D0 (en) | 2002-04-19 | 2002-04-19 | Novel compounds |
GB0221318A GB0221318D0 (en) | 2002-09-13 | 2002-09-13 | Novel compounds |
PCT/GB2003/000608 WO2003068749A1 (en) | 2002-02-15 | 2003-02-13 | Vanilloid receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60325025D1 true DE60325025D1 (de) | 2009-01-15 |
Family
ID=27739514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60325025T Expired - Lifetime DE60325025D1 (de) | 2002-02-15 | 2003-02-13 | Modulatoren des vanilloidrezeptors |
Country Status (10)
Country | Link |
---|---|
US (1) | US7538121B2 (de) |
EP (2) | EP1480954B1 (de) |
JP (1) | JP2005526723A (de) |
AR (1) | AR038420A1 (de) |
AT (1) | ATE416168T1 (de) |
AU (1) | AU2003245773A1 (de) |
DE (1) | DE60325025D1 (de) |
ES (1) | ES2316777T3 (de) |
TW (1) | TW200403223A (de) |
WO (1) | WO2003068749A1 (de) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2345044T3 (es) | 2002-02-01 | 2010-09-14 | Euro-Celtique S.A. | 2-piperazin-piridinas utiles para tratar el dolor. |
US6974818B2 (en) | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
AU2003241453A1 (en) | 2002-05-17 | 2003-12-02 | Janssen Pharmaceutica N.V. | Aminotetralin-derived urea modulators of vanilloid vr1 receptor |
RS114804A (en) | 2002-06-28 | 2006-12-15 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
US7262194B2 (en) | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
GB0221157D0 (en) * | 2002-09-12 | 2002-10-23 | Glaxo Group Ltd | Novel treatment |
US7157462B2 (en) | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
GB0226724D0 (en) * | 2002-11-15 | 2002-12-24 | Merck Sharp & Dohme | Therapeutic agents |
WO2004052846A1 (en) | 2002-12-06 | 2004-06-24 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
WO2004052845A1 (en) * | 2002-12-09 | 2004-06-24 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives as vanilloid receptor antagonists |
EP1575918A2 (de) * | 2002-12-19 | 2005-09-21 | Neurogen Corporation | Substituierte biaryl-4-carbonsäure-arylamid-derivate als capsaicin-rezeptor-modulatoren |
SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
CA2526361C (en) | 2003-05-20 | 2012-05-15 | Ajinomoto Co., Inc. | Amide derivative |
PL1632477T3 (pl) | 2003-06-12 | 2017-07-31 | Astellas Pharma Inc. | Pochodna benzamidu lub jej sól |
MY142655A (en) | 2003-06-12 | 2010-12-15 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
ATE492278T1 (de) * | 2003-07-23 | 2011-01-15 | Synta Pharmaceuticals Corp | Verbindungen gegen entzündungen und immun- relevante verwendungen |
DK1867644T3 (da) | 2003-07-24 | 2009-09-21 | Euro Celtique Sa | Heteroaryl-tetrahydropyridyl-forbindelser, der er anvendelige til behandling eller forebyggelse af smerte |
GB0319151D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
GB0319150D0 (en) | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
WO2005030753A2 (en) * | 2003-09-22 | 2005-04-07 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
PL1664041T3 (pl) * | 2003-09-22 | 2008-12-31 | Euro Celtique Sa | Przydatne do leczenia bólu związki fenylowo-karboksyamidowe |
DE602004019294D1 (de) | 2003-10-01 | 2009-03-19 | Xention Ltd | Tetrahydronaphthalin- und harnstoffderivate |
JP4667384B2 (ja) | 2003-10-07 | 2011-04-13 | レノビス, インコーポレイテッド | イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法 |
US7338950B2 (en) | 2003-10-07 | 2008-03-04 | Renovis, Inc. | Amide compounds as ion channel ligands and uses thereof |
GB2413129A (en) * | 2003-10-07 | 2005-10-19 | Renovis Inc | Aromatic amide compounds as ion channel ligands and uses thereof |
EP1737414A2 (de) * | 2004-01-23 | 2007-01-03 | Amgen Inc. | Vanilloid-rezeptor-liganden und ihre verwendung in der behandlung von entzündlichen und neuropathischen schmerzen |
US7544803B2 (en) | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
US7622579B2 (en) | 2004-06-28 | 2009-11-24 | Janssen Pharmaceutica Nv | Hetero isonipecotic modulators of vanilloid VR1 receptor |
WO2006006740A1 (ja) * | 2004-07-14 | 2006-01-19 | Japan Tobacco Inc. | 3−アミノベンズアミド化合物及びバニロイド受容体1型(vr1)活性阻害剤 |
KR101042490B1 (ko) | 2004-07-15 | 2011-06-16 | 니뽄 다바코 산교 가부시키가이샤 | 축합 벤즈아미드 화합물 및 바닐로이드 수용체 1형(vr1)활성 저해제 |
WO2006058338A2 (en) * | 2004-11-29 | 2006-06-01 | Janssen Pharmaceutica N.V. | 4 - piperidinecarboxamide derivatives as modulators of vanilloid vr1 receptor |
FR2880625B1 (fr) * | 2005-01-07 | 2007-03-09 | Sanofi Aventis Sa | Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
KR20060087386A (ko) | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
CA2616079C (en) * | 2005-07-22 | 2012-09-25 | Mochida Pharmaceutical Co., Ltd. | Novel heterocyclidene acetamide derivative |
FR2888847B1 (fr) * | 2005-07-22 | 2007-08-31 | Sanofi Aventis Sa | Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique |
FR2888848B1 (fr) * | 2005-07-22 | 2007-09-28 | Sanofi Aventis Sa | Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
US7429605B2 (en) | 2005-08-04 | 2008-09-30 | Hoffmann-La Roche Inc. | Phenylpyridine derivatives |
WO2007022946A1 (de) | 2005-08-21 | 2007-03-01 | Abbott Gmbh & Co. Kg | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
DE102005059479A1 (de) | 2005-12-13 | 2007-06-14 | Merck Patent Gmbh | Hydroxychinolinderivate |
TW200736227A (en) | 2005-12-23 | 2007-10-01 | Astrazeneca Ab | New compounds III |
JP4086895B2 (ja) | 2005-12-28 | 2008-05-14 | 日本たばこ産業株式会社 | 3,4−ジヒドロベンゾオキサジン化合物及びバニロイド受容体1型(vr1)活性阻害剤 |
US7906508B2 (en) * | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
JP5306987B2 (ja) * | 2006-03-16 | 2013-10-02 | エボテック (ユーエス) インコーポレイテッド | P2x7調節因子としてのビシクロへテロアリール化合物およびその使用 |
SG173320A1 (en) * | 2006-03-27 | 2011-08-29 | Nerviano Medical Sciences Srl | Pyridyl- and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors |
WO2008007211A1 (en) * | 2006-07-11 | 2008-01-17 | Pfizer Japan Inc. | Substituted n-bicyclicalkyl bicyclic carboxyamide compounds |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
EP2069302B1 (de) | 2006-09-15 | 2010-08-25 | Pfizer Inc. | Substituierte pyridylmethylbicyclocarboxyamidverbindungen |
US8158650B2 (en) | 2006-10-23 | 2012-04-17 | Pfizer Inc. | Substituted phenylmethyl bicyclocarboxyamide compounds |
WO2008057300A2 (en) * | 2006-10-27 | 2008-05-15 | Redpoint Bio Corporation | Trpvi antagonists and uses thereof |
US7964732B2 (en) | 2006-11-17 | 2011-06-21 | Pfizer Inc. | Substituted bicyclocarboxyamide compounds |
FR2910473B1 (fr) | 2006-12-26 | 2009-02-13 | Sanofi Aventis Sa | Derives de n-(amino-heteroaryl)-1h-pyrrolopyridine-2- carboxamides, leur preparation et leur application en therapeutique. |
US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
FR2911604B1 (fr) | 2007-01-19 | 2009-04-17 | Sanofi Aventis Sa | Derives de n-(heteroaryl-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique |
FR2911605B1 (fr) | 2007-01-19 | 2009-04-17 | Sanofi Aventis Sa | Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique |
PE20081692A1 (es) * | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
US20080186971A1 (en) * | 2007-02-02 | 2008-08-07 | Tarari, Inc. | Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic |
MY148657A (en) * | 2007-04-27 | 2013-05-15 | Purdue Pharma Lp | Trpv1 antagonists and uses thereof |
NZ579820A (en) | 2007-04-27 | 2011-01-28 | Purdue Pharma Lp | Therapeutic agents useful for treating pain |
CA2709879A1 (en) * | 2007-12-19 | 2009-06-25 | The Scripps Research Institute | Anilides and analogs as rho kinase inhibitors |
EP2234487A4 (de) * | 2007-12-19 | 2011-09-07 | Scripps Research Inst | Anilide und analoge als rho-kinasehemmer |
EP2234618A4 (de) * | 2007-12-21 | 2011-04-27 | Scripps Research Inst | Benzopyrane und analoga als rho-kinase-inhibitoren |
FR2926554B1 (fr) | 2008-01-22 | 2010-03-12 | Sanofi Aventis | Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
FR2926553B1 (fr) * | 2008-01-23 | 2010-02-19 | Sanofi Aventis | Derives d'indole-2-carboxamides et d'azaindole-2- carboxamides substitues par un groupe silanyle, leur preparation et leur application en therapeutique |
JP5372138B2 (ja) | 2008-04-18 | 2013-12-18 | テウン ファーマシューティカル カンパニー,リミテッド | 新規ベンゾオキサジンベンズイミダゾール誘導体、これを含む薬学組成物およびこの用途 |
US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
JP2012525386A (ja) | 2009-05-01 | 2012-10-22 | アエリエ・ファーマシューティカルズ・インコーポレーテッド | 疾患の治療のための二重機構阻害剤 |
RS56352B2 (sr) * | 2009-06-25 | 2023-02-28 | Alkermes Pharma Ireland Ltd | Heterociklična jedinjenja za lečenje neuroloških i psiholoških poremećaja |
US8686009B2 (en) | 2009-06-25 | 2014-04-01 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds |
US8754219B2 (en) | 2010-04-27 | 2014-06-17 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
ES2691671T3 (es) | 2010-06-24 | 2018-11-28 | Alkermes Pharma Ireland Limited | Profármacos de compuestos NH-acídicos: derivados de éster, carbonato, carbamato y fosfonato |
KR101293384B1 (ko) | 2010-10-13 | 2013-08-05 | 주식회사 대웅제약 | 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도 |
LT3156056T (lt) | 2011-03-18 | 2024-02-26 | Alkermes Pharma Ireland Limited | Farmacinės kompozicijos, apimančios sorbitano esterius |
ME02609B (de) | 2011-06-22 | 2017-06-20 | Purdue Pharma Lp | Trpv1-antagonisten mit dihydroxy-substituent und ihre verwendung |
JP5952912B2 (ja) | 2011-12-15 | 2016-07-13 | アルカーメス ファーマ アイルランド リミテッド | 二級アミン化合物のプロドラッグ |
FR2984323B1 (fr) * | 2011-12-16 | 2019-08-30 | L'oreal | Coupleur de structure 7 amino-1,2,3,4-tetrahydroquinoleines, composition tinctoriale en comprenant, procedes et utilisations |
FR2984318B1 (fr) | 2011-12-16 | 2014-06-27 | Oreal | Coupleur de structure 7 amino-1,2,3,4-tetrahydroquinoleines cationiques, composition tinctoriale en comprenant, procedes et utilisations |
AU2013235519C1 (en) | 2012-03-19 | 2018-04-26 | Alkermes Pharma Ireland Limited | Pharmaaceutical compositions comprising fatty acid esters |
EP2827867B1 (de) | 2012-03-19 | 2019-11-06 | Alkermes Pharma Ireland Limited | Pharmazeutische zusammensetzungen mit glycerinestern |
JP6333802B2 (ja) | 2012-03-19 | 2018-05-30 | アルカームス ファーマ アイルランド リミテッド | ベンジルアルコールを含む医薬組成物 |
EP2897592B1 (de) | 2012-09-19 | 2020-02-19 | Alkermes Pharma Ireland Limited | Pharmazeutische zusammensetzungen mit verbesserter lagerstabilität |
CA2894399A1 (en) | 2012-12-06 | 2014-06-12 | Quanticel Pharmaceuticals, Inc. | Histone demethylase inhibitors |
PT3811943T (pt) | 2013-03-15 | 2023-03-15 | Aerie Pharmaceuticals Inc | Composto para uso no tratamento de distúrbios oculares |
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-
2003
- 2003-02-13 DE DE60325025T patent/DE60325025D1/de not_active Expired - Lifetime
- 2003-02-13 EP EP03739564A patent/EP1480954B1/de not_active Expired - Lifetime
- 2003-02-13 ES ES03739564T patent/ES2316777T3/es not_active Expired - Lifetime
- 2003-02-13 AR ARP030100474A patent/AR038420A1/es unknown
- 2003-02-13 WO PCT/GB2003/000608 patent/WO2003068749A1/en active Application Filing
- 2003-02-13 TW TW092102941A patent/TW200403223A/zh unknown
- 2003-02-13 JP JP2003567880A patent/JP2005526723A/ja active Pending
- 2003-02-13 EP EP08170191A patent/EP2033953A1/de not_active Withdrawn
- 2003-02-13 AT AT03739564T patent/ATE416168T1/de not_active IP Right Cessation
- 2003-02-13 AU AU2003245773A patent/AU2003245773A1/en not_active Abandoned
- 2003-02-13 US US10/503,648 patent/US7538121B2/en not_active Expired - Fee Related
Also Published As
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AU2003245773A1 (en) | 2003-09-04 |
ES2316777T3 (es) | 2009-04-16 |
WO2003068749A1 (en) | 2003-08-21 |
US7538121B2 (en) | 2009-05-26 |
JP2005526723A (ja) | 2005-09-08 |
EP2033953A1 (de) | 2009-03-11 |
AR038420A1 (es) | 2005-01-12 |
US20060142333A1 (en) | 2006-06-29 |
TW200403223A (en) | 2004-03-01 |
EP1480954B1 (de) | 2008-12-03 |
ATE416168T1 (de) | 2008-12-15 |
EP1480954A1 (de) | 2004-12-01 |
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