BR9812041B1 - processo para a preparação de derivados n-acilados (hetero) aromáticos da hidroxilamina. - Google Patents

processo para a preparação de derivados n-acilados (hetero) aromáticos da hidroxilamina.

Info

Publication number
BR9812041B1
BR9812041B1 BRPI9812041-7A BR9812041A BR9812041B1 BR 9812041 B1 BR9812041 B1 BR 9812041B1 BR 9812041 A BR9812041 A BR 9812041A BR 9812041 B1 BR9812041 B1 BR 9812041B1
Authority
BR
Brazil
Prior art keywords
hetero
acylated
preparation
hydroxylamine derivatives
aromatic hydroxylamine
Prior art date
Application number
BRPI9812041-7A
Other languages
English (en)
Other versions
BR9812041A (pt
Inventor
Ralf Klintz
Norbert Goetz
Michael Keil
Manfred Heilig
Horst Wingert
Uwe Josef Vogelbacher
Josef Wahl
Frank Wetterich
Gregor Daun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1997138864 external-priority patent/DE19738864A1/de
Priority claimed from DE1997138862 external-priority patent/DE19738862A1/de
Application filed filed Critical
Publication of BR9812041A publication Critical patent/BR9812041A/pt
Publication of BR9812041B1 publication Critical patent/BR9812041B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08Hydroxylamino compounds or their ethers or esters
    • C07C239/12Hydroxylamino compounds or their ethers or esters having nitrogen atoms of hydroxylamino groups further bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/50Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/40Nitrogen atoms attached in position 8
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • C07D231/20One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI9812041-7A 1997-09-05 1998-08-21 processo para a preparação de derivados n-acilados (hetero) aromáticos da hidroxilamina. BR9812041B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1997138864 DE19738864A1 (de) 1997-09-05 1997-09-05 Verfahren zur Herstellung N-acylierter (hetero)aromatischer Hydroxylamine
DE1997138862 DE19738862A1 (de) 1997-09-05 1997-09-05 Verfahren zur Herstellung von N-Aryl- und N-Heterocyclylhydroxylaminen
PCT/EP1998/005332 WO1999012911A1 (de) 1997-09-05 1998-08-21 Verfahren zur herstellung (hetero)aromatischer hydroxylamine

Publications (2)

Publication Number Publication Date
BR9812041A BR9812041A (pt) 2000-09-26
BR9812041B1 true BR9812041B1 (pt) 2009-08-11

Family

ID=26039701

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9812041-7A BR9812041B1 (pt) 1997-09-05 1998-08-21 processo para a preparação de derivados n-acilados (hetero) aromáticos da hidroxilamina.

Country Status (18)

Country Link
US (1) US6255489B1 (pt)
EP (1) EP1012144B1 (pt)
JP (1) JP4353633B2 (pt)
KR (1) KR100512227B1 (pt)
CN (1) CN1117080C (pt)
AT (1) ATE234289T1 (pt)
AU (1) AU9264398A (pt)
BR (1) BR9812041B1 (pt)
CA (1) CA2302937C (pt)
CZ (1) CZ297014B6 (pt)
DE (1) DE59807486D1 (pt)
DK (1) DK1012144T3 (pt)
EA (1) EA003733B1 (pt)
ES (1) ES2195388T3 (pt)
HU (1) HUP0004063A3 (pt)
IL (1) IL134675A0 (pt)
PL (1) PL200408B1 (pt)
WO (1) WO1999012911A1 (pt)

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WO2001023358A1 (fr) * 1999-09-27 2001-04-05 Sagami Chemical Research Center Derives pyrazole, intermediaires pour la preparation de ces derives, procedes de preparation des derives et intermediaires, et herbicides dont ces derives sont le principe actif
ES2355472T3 (es) 2002-05-22 2011-03-28 Amgen Inc. Derivados de aminopirimidina para su uso como ligandos del receptor vaniloide para el tratamiento del dolor.
WO2003099793A1 (en) * 2002-05-24 2003-12-04 Takeda Pharmaceutical Company Limited 1,2-azole derivatives with hypoglycemic and hypolipidemic activity
EP1717220A3 (en) * 2002-08-08 2007-08-22 Amgen, Inc Vanilloid receptor ligands and their use in treatments
MY139645A (en) 2004-02-11 2009-10-30 Amgen Inc Vanilloid receptor ligands and their use in treatments
US7534798B2 (en) 2004-02-11 2009-05-19 Amgen Inc. Vanilloid receptor ligands and their use in treatments
WO2006089311A1 (en) * 2005-02-15 2006-08-24 Amgen Inc. Vanilloid receptor ligands and their use in treatments
NL2000351C2 (nl) * 2005-12-22 2007-09-11 Pfizer Prod Inc Estrogeen-modulatoren.
CN101531614B (zh) * 2009-04-14 2012-05-23 大连理工大学 一种纳米Pt/C催化芳香硝基物选择加氢制备芳香羟胺的方法
AR078156A1 (es) 2009-09-04 2011-10-19 Basf Se Proceso para preparar 1-fenilpirazoles
US8642780B2 (en) 2010-03-18 2014-02-04 Basf Se N-carbomethoxy-N-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3′-yloxymethylene)-anilides
JP2013540739A (ja) 2010-09-21 2013-11-07 ビーエーエスエフ ソシエタス・ヨーロピア 置換n−フェニルヒドロキシルアミンの製造のためのプロセス
EP2683692B1 (en) 2011-03-09 2015-05-13 Basf Se Process for preparing substituted n-phenylhydroxylamines
CN102399190A (zh) * 2011-12-20 2012-04-04 河南中医学院 一种经济型合成吡唑醚菌酯及其方法
CN103304356B (zh) * 2012-03-12 2016-01-20 北京乐威泰克医药技术有限公司 羟胺的合成方法
WO2014089364A1 (en) 2012-12-06 2014-06-12 Quanticel Pharmaceuticals, Inc Histone demethylase inhibitors
CN104211641B (zh) * 2014-08-19 2016-08-24 山东康乔生物科技有限公司 一种吡唑醚菌酯的合成工艺
CN104557712A (zh) * 2014-12-26 2015-04-29 北京颖泰嘉和生物科技有限公司 芳族羟胺化合物的制备方法和n-酰化芳族羟胺化合物的制备方法
WO2016113741A1 (en) 2015-01-14 2016-07-21 Adama Makhteshim Ltd. Process for preparing 1-(4-chlorophenyl)-3-[(2-nitrophenyl)methoxy]-1h-pyrazole
WO2016181386A1 (en) 2015-05-14 2016-11-17 Adama Makhteshim Ltd. Process for preparing a hydroxylamine pyrazole compound
CA2994399C (en) 2015-08-10 2023-10-17 Basf Se A process for preparing crystalline methyl n-[2-[[[1-(4-chlorophen yl)-1h-pyrazol-3-yl]oxy]methyl]phenyl]-n-methoxycarbamate
CN105218450A (zh) * 2015-11-06 2016-01-06 江苏托球农化股份有限公司 一种吡唑醚菌酯的绿色生产工艺
CN105503729A (zh) * 2015-12-04 2016-04-20 安徽国星生物化学有限公司 一种n-羟基-n-2-[n-(对氯苯基)吡唑-3-氧基甲基]苯基羟胺的合成方法
CN105949125A (zh) * 2016-06-22 2016-09-21 石家庄市深泰化工有限公司 一种催化合成吡唑醚菌酯的方法
CN107759520A (zh) * 2016-08-17 2018-03-06 浙江中山化工集团股份有限公司 一种n‑羟基‑n‑2‑[(n‑对氯苯基)‑3‑吡唑氧基甲基]苯基羟胺的合成工艺
CN106749025B (zh) * 2016-11-14 2019-10-08 四川福思达生物技术开发有限责任公司 一种简洁合成吡唑醚菌酯的方法
CN106632046A (zh) * 2016-12-12 2017-05-10 利民化工股份有限公司 一种吡唑醚菌酯的合成方法
CN108203409B (zh) * 2016-12-20 2023-09-05 海利尔药业集团股份有限公司 一种取代的n-羟基苯胺的制备方法
EP3357905A1 (de) * 2017-02-01 2018-08-08 Solvias AG Herstellung n-substituierter aromatischer hydroxylamine
CN107673999A (zh) * 2017-10-30 2018-02-09 青岛瀚生生物科技股份有限公司 制备吡唑醚菌酯中间体的方法
EP3587391A1 (en) 2018-06-22 2020-01-01 Basf Se Process for preparing nitrobenzyl bromides

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DE4423612A1 (de) 1994-07-06 1996-01-11 Basf Ag 2-[(Dihydro)pyrazolyl-3'-oxymethylen]-anilide, Verfahren zu ihrer Herstelung und ihre Verwendung
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Also Published As

Publication number Publication date
PL339222A1 (en) 2000-12-04
CZ2000764A3 (cs) 2000-06-14
EP1012144B1 (de) 2003-03-12
PL200408B1 (pl) 2009-01-30
JP4353633B2 (ja) 2009-10-28
WO1999012911A1 (de) 1999-03-18
IL134675A0 (en) 2001-04-30
DE59807486D1 (de) 2003-04-17
KR100512227B1 (ko) 2005-09-05
AU9264398A (en) 1999-03-29
BR9812041A (pt) 2000-09-26
DK1012144T3 (da) 2003-07-14
US6255489B1 (en) 2001-07-03
ATE234289T1 (de) 2003-03-15
JP2001515890A (ja) 2001-09-25
CN1117080C (zh) 2003-08-06
CA2302937A1 (en) 1999-03-18
EA003733B1 (ru) 2003-08-28
EP1012144A1 (de) 2000-06-28
CA2302937C (en) 2008-12-16
CZ297014B6 (cs) 2006-08-16
HUP0004063A3 (en) 2002-11-28
KR20010023676A (ko) 2001-03-26
CN1271348A (zh) 2000-10-25
EA200000294A1 (ru) 2000-10-30
ES2195388T3 (es) 2003-12-01
HUP0004063A2 (en) 2001-03-28

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/11/2009, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 03.11.2019