AR078156A1 - Proceso para preparar 1-fenilpirazoles - Google Patents
Proceso para preparar 1-fenilpirazolesInfo
- Publication number
- AR078156A1 AR078156A1 ARP100103245A ARP100103245A AR078156A1 AR 078156 A1 AR078156 A1 AR 078156A1 AR P100103245 A ARP100103245 A AR P100103245A AR P100103245 A ARP100103245 A AR P100103245A AR 078156 A1 AR078156 A1 AR 078156A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- haloalkyl
- alkoxy
- haloalkoxy
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Reivindicacion 1: Un proceso para preparar 1-fenilpirazoles de la formula (1) en donde cada R1 se selecciona, independientemente, de cloro, fluor, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4; n es 1, 2 o 3; cada R2 se selecciona, independientemente, de ciano, nitro, halogeno, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4, haloalcoxi C1-4, alquiltio C1-4 y alcoxicarbonilo C1-4; m es 0,1 o 2: A es alquilo C1-12, arilo o aril-C1-4-alquilo, en donde A tiene, opcionalmente, 1, 2, 3 o 4 sustituyentes que se seleccionan de halogeno, ciano, nitro, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4, haloalcoxi C1-4, un grupo Ra, Rb, Rc y un grupo Rd en donde R4 es H, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4, haloalcoxi C1-4, arilo, ariloxi, aril-C1-4-alcoxi, en donde los grupos arilo en los 3 ultimos radicales tienen, opcionalmente, 1, 2, 3 o 4 sustituyentes que se seleccionan de halogeno, ciano, nitro, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4, y R5 es alquilo C1-4, haloalquilo C1-4 o aril-C1-4-alquilo, en donde el grupo arilo en el ultimo radical tiene, opcionalmente, 1, 2, 3 o 4 sustituyentes que se seleccionan de halogeno, ciano, nitro, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4, caracterizado porque comprende la siguiente etapa; (i) hacer reaccionar un haluro de fenilo de la formula (2) con un derivado de pirazol de la formula (3) en donde X es cloro, yodo o bromo; y cada R1, n, R2, m y A es como se definio anteriormente, en presencia de una base y sistema catalítico que comprende un ligando y un compuesto de metal seleccionado de compuestos de paladio, compuestos de hierro o compuestos de cobre. Reivindicacion 15: Un compuesto caracterizado porque tiene la formula (2) en donde cada R3 se selecciona, independientemente, de halogeno, ciano, alquilo C1-4, haloalquilo C1-4, alcoxi C1-4 y haloalcoxi C1-4, p es 0, 1, 2 o 3, Y es nitro, un grupo Ra, Rb, Rc o un grupo Rd, y, cada R2, m, Ra, Rb, Rc y Rd es como se define en la reivindicacion 1.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09169528 | 2009-09-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR078156A1 true AR078156A1 (es) | 2011-10-19 |
Family
ID=41343343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100103245A AR078156A1 (es) | 2009-09-04 | 2010-09-03 | Proceso para preparar 1-fenilpirazoles |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8362271B2 (es) |
| EP (1) | EP2473485B1 (es) |
| JP (1) | JP2013503834A (es) |
| CN (1) | CN102482225B (es) |
| AR (1) | AR078156A1 (es) |
| BR (1) | BR112012004562B1 (es) |
| IL (1) | IL218140A0 (es) |
| WO (1) | WO2011026937A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8362271B2 (en) * | 2009-09-04 | 2013-01-29 | Basf Se | Process for preparing 1-phenylpyrazoles |
| US9375311B2 (en) | 2013-05-03 | 2016-06-28 | Medtronic, Inc. | Prosthetic valves and associated appartuses, systems and methods |
| US9629718B2 (en) | 2013-05-03 | 2017-04-25 | Medtronic, Inc. | Valve delivery tool |
| CN104211641B (zh) * | 2014-08-19 | 2016-08-24 | 山东康乔生物科技有限公司 | 一种吡唑醚菌酯的合成工艺 |
| CN106117143B (zh) * | 2016-06-28 | 2019-01-08 | 青岛瀚生生物科技股份有限公司 | 一种吡唑醚菌酯的制备方法 |
| CN106045911B (zh) * | 2016-07-02 | 2018-03-02 | 安徽广信农化股份有限公司 | 一种气相沉积法提纯吡唑醚菌酯的工艺方法 |
| LT3538525T (lt) | 2016-11-08 | 2022-09-26 | Bristol-Myers Squibb Company | Propiono rūgštys, pakeistos 3 padėtyje, kaip alfa v integrino inhibitoriai |
| CN108117521A (zh) * | 2018-03-05 | 2018-06-05 | 安徽国星生物化学有限公司 | 一种吡唑醚菌酯的反向重结晶方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4415484A1 (de) | 1994-05-03 | 1995-11-09 | Basf Ag | Verfahren zur Herstellung von 1-(Het)aryl-3-hydroxy-pyrazolen |
| DE4423612A1 (de) | 1994-07-06 | 1996-01-11 | Basf Ag | 2-[(Dihydro)pyrazolyl-3'-oxymethylen]-anilide, Verfahren zu ihrer Herstelung und ihre Verwendung |
| DE19502700A1 (de) | 1995-01-28 | 1996-08-01 | Basf Ag | Verfahren zur Herstellung von N-Aryl- und N-Hetarylhydroxylaminen |
| DE19732692C2 (de) | 1997-07-30 | 2001-01-18 | Basf Ag | Verfahren zur Herstellung von 2-(Pyrazolyl-3'-oxymethylen)nitrobenzolen |
| JP4353633B2 (ja) | 1997-09-05 | 2009-10-28 | ビーエーエスエフ ソシエタス・ヨーロピア | （ヘテロ）芳香族ヒドロキシルアミンの製造方法 |
| DE19756115A1 (de) * | 1997-12-17 | 1999-06-24 | Basf Ag | Substituierte Phenylpyrazolone, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung zur Bekämpfung von Schadpilzen und tierischen Schädlingen |
| JP2002516909A (ja) | 1998-06-05 | 2002-06-11 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | 置換１−（４−アミノフェニル）ピラゾール及び抗炎症剤としてのそれらの使用 |
| JP2004035499A (ja) * | 2002-07-05 | 2004-02-05 | Nissan Chem Ind Ltd | フェニルカーバメート化合物および農園芸用殺菌殺虫剤 |
| US8362271B2 (en) * | 2009-09-04 | 2013-01-29 | Basf Se | Process for preparing 1-phenylpyrazoles |
-
2010
- 2010-09-03 US US13/393,624 patent/US8362271B2/en active Active
- 2010-09-03 EP EP10747888.5A patent/EP2473485B1/en not_active Not-in-force
- 2010-09-03 AR ARP100103245A patent/AR078156A1/es unknown
- 2010-09-03 WO PCT/EP2010/062950 patent/WO2011026937A1/en active Application Filing
- 2010-09-03 CN CN201080039277.5A patent/CN102482225B/zh not_active Expired - Fee Related
- 2010-09-03 BR BR112012004562-8A patent/BR112012004562B1/pt active IP Right Grant
- 2010-09-03 JP JP2012527336A patent/JP2013503834A/ja active Pending
-
2012
- 2012-02-16 IL IL218140A patent/IL218140A0/en unknown
-
2013
- 2013-01-10 US US13/738,230 patent/US8933246B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8362271B2 (en) | 2013-01-29 |
| US8933246B2 (en) | 2015-01-13 |
| US20120165544A1 (en) | 2012-06-28 |
| WO2011026937A1 (en) | 2011-03-10 |
| IL218140A0 (en) | 2012-06-28 |
| EP2473485A1 (en) | 2012-07-11 |
| CN102482225B (zh) | 2016-10-05 |
| EP2473485B1 (en) | 2014-04-23 |
| JP2013503834A (ja) | 2013-02-04 |
| US20130131352A1 (en) | 2013-05-23 |
| BR112012004562A2 (pt) | 2020-08-18 |
| BR112012004562B1 (pt) | 2021-02-17 |
| CN102482225A (zh) | 2012-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |