BR112016013896A2 - métodos de tratamento de câncer positivo para her2 usando antagonistas de ligação do eixo de pd-1 e anticorpos anti-her2 - Google Patents

métodos de tratamento de câncer positivo para her2 usando antagonistas de ligação do eixo de pd-1 e anticorpos anti-her2

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Publication number
BR112016013896A2
BR112016013896A2 BR112016013896A BR112016013896A BR112016013896A2 BR 112016013896 A2 BR112016013896 A2 BR 112016013896A2 BR 112016013896 A BR112016013896 A BR 112016013896A BR 112016013896 A BR112016013896 A BR 112016013896A BR 112016013896 A2 BR112016013896 A2 BR 112016013896A2
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Brazil
Prior art keywords
her2
axis binding
cancer treatment
treatment methods
positive cancer
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BR112016013896A
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English (en)
Inventor
Ebens Allen
Irving Bryan
Li Ji
S Dennis Mark
T Junttila Teemu
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Genentech Inc
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Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112016013896A2 publication Critical patent/BR112016013896A2/pt

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Abstract

a invenção fornece composições e métodos para tratar cânceres positivos para her2. o método compreende administrar um antagonista da ligação do eixo de pd-1 e um anticorpo direcionado para her2.
BR112016013896A 2013-12-17 2014-12-17 métodos de tratamento de câncer positivo para her2 usando antagonistas de ligação do eixo de pd-1 e anticorpos anti-her2 BR112016013896A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361917264P 2013-12-17 2013-12-17
PCT/US2014/070992 WO2015095418A1 (en) 2013-12-17 2014-12-17 Methods of treating her2-positive cancers using pd-1 axis binding antagonists and anti-her2 antibodies

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BR112016013896A2 true BR112016013896A2 (pt) 2017-10-10

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US (9) US10570213B2 (pt)
EP (4) EP3083692B1 (pt)
JP (5) JP2017507900A (pt)
KR (4) KR20240017102A (pt)
CN (3) CN112353943A (pt)
AU (3) AU2014364601A1 (pt)
BR (1) BR112016013896A2 (pt)
CA (2) CA2931812A1 (pt)
DK (1) DK3083686T4 (pt)
ES (1) ES2763429T5 (pt)
FI (1) FI3083686T4 (pt)
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BR112015024926A2 (pt) 2013-04-16 2017-10-10 Genentech Inc composições, artigo de fabricação, métodos para tratar um paciente com câncer, para avaliar uma composição, para avaliar a atividade biológica, para produzir uma composição e para avaliar a fragmentação de uma composição e variante de pertuzumabe
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