BR112015021993A2 - composições de cultura celular com antioxidantes e métodos para produção de polipeptídeo - Google Patents

composições de cultura celular com antioxidantes e métodos para produção de polipeptídeo

Info

Publication number
BR112015021993A2
BR112015021993A2 BR112015021993A BR112015021993A BR112015021993A2 BR 112015021993 A2 BR112015021993 A2 BR 112015021993A2 BR 112015021993 A BR112015021993 A BR 112015021993A BR 112015021993 A BR112015021993 A BR 112015021993A BR 112015021993 A2 BR112015021993 A2 BR 112015021993A2
Authority
BR
Brazil
Prior art keywords
methods
cell culture
producing polypeptide
culture compositions
antioxidant
Prior art date
Application number
BR112015021993A
Other languages
English (en)
Other versions
BR112015021993A8 (pt
Inventor
Vijayasankaran Natarajan
Varma Sharat
J Meier Steven
Yang Yi
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50639996&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015021993(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112015021993A2 publication Critical patent/BR112015021993A2/pt
Publication of BR112015021993A8 publication Critical patent/BR112015021993A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/32Amino acids
    • C12N2500/33Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/44Thiols, e.g. mercaptoethanol
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/46Amines, e.g. putrescine

Abstract

resumo patente de invenção: "composições de cultura celular com antioxidantes e métodos para produção de polipeptídeo". meios de cultura celular que compreendem antioxidantes são fornecidos aqui como são os métodos de uso dos meios para cultura celular e produção de polipeptídeo a partir de células. composições compreendendo os polipeptídeos, tais como polipeptídeos, produzidos pelos métodos aqui são também fornecidas.
BR112015021993A 2013-03-15 2014-03-14 polipeptídeo, métodos para sua produção, métodos para cultivo de uma célula, composição farmacêutica, kit, e meio de cultura celular BR112015021993A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361799602P 2013-03-15 2013-03-15
PCT/US2014/029772 WO2014145098A1 (en) 2013-03-15 2014-03-14 Cell culture compositions with antioxidants and methods for polypeptide production

Publications (2)

Publication Number Publication Date
BR112015021993A2 true BR112015021993A2 (pt) 2017-07-18
BR112015021993A8 BR112015021993A8 (pt) 2019-12-03

Family

ID=50639996

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015021993A BR112015021993A8 (pt) 2013-03-15 2014-03-14 polipeptídeo, métodos para sua produção, métodos para cultivo de uma célula, composição farmacêutica, kit, e meio de cultura celular

Country Status (19)

Country Link
US (5) US10017732B2 (pt)
EP (2) EP2970875B1 (pt)
JP (2) JP6591395B2 (pt)
KR (2) KR20210037745A (pt)
CN (2) CN105121628B (pt)
AU (3) AU2014233393B2 (pt)
BR (1) BR112015021993A8 (pt)
CA (1) CA2903596C (pt)
ES (1) ES2798307T3 (pt)
HK (1) HK1218141A1 (pt)
HR (1) HRP20200893T1 (pt)
IL (2) IL240644B (pt)
MX (2) MX360779B (pt)
PL (1) PL2970875T3 (pt)
RU (2) RU2020111947A (pt)
SG (3) SG10201809452RA (pt)
SI (1) SI2970875T1 (pt)
WO (1) WO2014145098A1 (pt)
ZA (2) ZA201506155B (pt)

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BR112021025769A2 (pt) 2019-12-06 2022-04-12 Regeneron Pharma Composições de proteína anti-vegf e métodos para a produção das mesmas
WO2023194946A1 (en) * 2022-04-06 2023-10-12 Kashiv Biosciences, Llc An improved cell culture process for production of protein

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NZ712315A (en) 2021-07-30
ES2798307T3 (es) 2020-12-10
EP2970875B1 (en) 2020-04-15
SI2970875T1 (sl) 2020-08-31
ZA201805630B (en) 2019-11-27
SG11201507367PA (en) 2015-10-29
JP2019141053A (ja) 2019-08-29
CN105121628B (zh) 2020-03-24
CA2903596A1 (en) 2014-09-18
BR112015021993A8 (pt) 2019-12-03
KR20210037745A (ko) 2021-04-06
EP3712252A1 (en) 2020-09-23
US20210017488A1 (en) 2021-01-21
IL240644B (en) 2020-04-30
PL2970875T3 (pl) 2020-08-10
MX360779B (es) 2018-11-16
JP2016514461A (ja) 2016-05-23
AU2020223634A1 (en) 2020-09-10
EP2970875A1 (en) 2016-01-20
KR102235452B1 (ko) 2021-04-02
KR20150131172A (ko) 2015-11-24
AU2014233393A1 (en) 2015-09-10
US10676710B2 (en) 2020-06-09
JP6843911B2 (ja) 2021-03-17
CN105121628A (zh) 2015-12-02
RU2718986C2 (ru) 2020-04-15
ZA201506155B (en) 2018-11-28
JP6591395B2 (ja) 2019-10-16
SG10201809452RA (en) 2018-11-29
US20190144817A1 (en) 2019-05-16
US10829732B2 (en) 2020-11-10
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