BR112013010688A2 - anticorpos anti c-met - Google Patents

anticorpos anti c-met

Info

Publication number
BR112013010688A2
BR112013010688A2 BR112013010688A BR112013010688A BR112013010688A2 BR 112013010688 A2 BR112013010688 A2 BR 112013010688A2 BR 112013010688 A BR112013010688 A BR 112013010688A BR 112013010688 A BR112013010688 A BR 112013010688A BR 112013010688 A2 BR112013010688 A2 BR 112013010688A2
Authority
BR
Brazil
Prior art keywords
met antibodies
antibodies
met
Prior art date
Application number
BR112013010688A
Other languages
English (en)
Other versions
BR112013010688B1 (pt
Inventor
Anna Hultberg
Cristina Basilico
Els Festjens
Johannes De Haard
Michael Saunders
Natalie De Jonge
Paulo Michieli
Torsten Dreier
Original Assignee
Argen X Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Argen X Bv filed Critical Argen X Bv
Priority to BR122014027420-3A priority Critical patent/BR122014027420A2/pt
Publication of BR112013010688A2 publication Critical patent/BR112013010688A2/pt
Publication of BR112013010688B1 publication Critical patent/BR112013010688B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112013010688-3A 2010-11-03 2011-11-03 combinações de anticorpos c-met BR112013010688B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122014027420-3A BR122014027420A2 (pt) 2010-11-03 2011-11-03 Anticorpos anti c-met

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40986610P 2010-11-03 2010-11-03
US61/409,866 2010-11-03
PCT/EP2011/069369 WO2012059561A1 (en) 2010-11-03 2011-11-03 Anti c-met antibodies

Publications (2)

Publication Number Publication Date
BR112013010688A2 true BR112013010688A2 (pt) 2016-08-09
BR112013010688B1 BR112013010688B1 (pt) 2020-11-17

Family

ID=44906140

Family Applications (3)

Application Number Title Priority Date Filing Date
BR112013010688-3A BR112013010688B1 (pt) 2010-11-03 2011-11-03 combinações de anticorpos c-met
BR122014027420-3A BR122014027420A2 (pt) 2010-11-03 2011-11-03 Anticorpos anti c-met
BR112013010687A BR112013010687A2 (pt) 2010-11-03 2011-11-03 combinações de anticorpos c-met

Family Applications After (2)

Application Number Title Priority Date Filing Date
BR122014027420-3A BR122014027420A2 (pt) 2010-11-03 2011-11-03 Anticorpos anti c-met
BR112013010687A BR112013010687A2 (pt) 2010-11-03 2011-11-03 combinações de anticorpos c-met

Country Status (12)

Country Link
US (7) US8637027B2 (pt)
EP (3) EP2635603B1 (pt)
JP (3) JP5857060B2 (pt)
CN (2) CN103562223B (pt)
AU (3) AU2011325097B2 (pt)
BR (3) BR112013010688B1 (pt)
CA (2) CA2816745C (pt)
DK (1) DK2635602T3 (pt)
ES (1) ES2594493T3 (pt)
IL (2) IL226112B (pt)
RU (2) RU2608644C2 (pt)
WO (2) WO2012059561A1 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8444976B2 (en) 2008-07-02 2013-05-21 Argen-X B.V. Antigen binding polypeptides
EP2143441A1 (en) * 2008-07-08 2010-01-13 Pierre Fabre Medicament Combination of a c-Met antagonist and an aminoheteroaryl compound for the treatment of cancer
AU2011325097B2 (en) 2010-11-03 2015-05-21 Argenx Bvba Anti c-Met antibodies
KR20130036993A (ko) * 2011-10-05 2013-04-15 삼성전자주식회사 c-Met의 SEMA 도메인 내의 에피토프에 특이적으로 결합하는 항체
PT2768857T (pt) * 2011-10-19 2020-01-27 Novimmune Sa Métodos para purificar anticorpos
US9926364B2 (en) * 2011-11-03 2018-03-27 Argen-X N.V. Chimeric human-llama antigens and methods of use
RU2014124842A (ru) 2011-11-21 2015-12-27 Дженентек, Инк. Очистка анти-с-мет антител
WO2013079973A1 (en) * 2011-12-02 2013-06-06 Di Cara Danielle Marie Antibodies against hgf - receptor and uses
EP2807189B1 (en) 2012-01-23 2019-03-20 Ablynx N.V. Sequences directed against hepatocyte growth factor (hgf) and polypeptides comprising the same for the treatment of cancers and/or tumors
US9931400B2 (en) 2012-09-12 2018-04-03 Samsung Electronics Co., Ltd. Method of combination therapy for prevention or treatment of c-Met or angiogenesis factor induced diseases
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
US9535055B2 (en) * 2013-03-28 2017-01-03 Samsung Electronics Co., Ltd. Marker for determining effects of anti-c-Met antibody and method of determining effects of anti-c-Met antibody using the marker
EP2786765B1 (en) * 2013-04-01 2018-10-03 Samsung Electronics Co., Ltd. Composition for combination therapy comprising an anti-C-met antibody and a FGFR inhibitor
KR102139607B1 (ko) * 2013-04-01 2020-07-30 삼성전자주식회사 항 c-Met 항체 및 FGFR 저해제를 포함하는 병용 투여용 약학 조성물
US10214593B2 (en) 2013-04-02 2019-02-26 Samsung Electronics Co., Ltd. Anti-idiotype antibody against anti-c-MET antibody
KR102060540B1 (ko) 2013-04-03 2019-12-31 삼성전자주식회사 항 c-Met 항체 및 항 Ang2 항체를 포함하는 병용 투여용 약학 조성물
SG11201508875TA (en) 2013-04-30 2015-11-27 Agency Science Tech & Res Mab 2 anti-met antibody
KR102186363B1 (ko) * 2013-09-06 2020-12-04 삼성전자주식회사 c-Met 저해제 및 베타-카테닌 저해제를 포함하는 병용 투여용 약학 조성물
KR102192591B1 (ko) * 2013-09-09 2020-12-18 삼성전자주식회사 c-Met 저해제 및 c-Myc 저해제를 포함하는 병용 투여용 약학 조성물
ES2851925T3 (es) * 2014-07-29 2021-09-09 Wellmarker Bio Co Ltd Inhibidores de MET e IGSF1 para el tratamiento de cáncer
BR112017005202A2 (pt) * 2014-09-16 2017-12-12 Symphogen As anticorpos anti-met e composições
CN107613974B (zh) * 2015-03-16 2021-01-15 塞尔德克斯医疗公司 抗-met抗体及其使用方法
GB201611123D0 (en) * 2016-06-27 2016-08-10 Euremab Srl Anti met antibodiesand uses thereof
CN118005799A (zh) * 2016-09-23 2024-05-10 马伦戈治疗公司 包含λ轻链和κ轻链的多特异性抗体分子
TWI782930B (zh) 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
WO2018221969A1 (en) * 2017-05-30 2018-12-06 Chong Kun Dang Pharmaceutical Corp. A novel anti-c-met antibody and use thereof
MY192630A (en) 2017-05-30 2022-08-29 Chong Kun Dang Pharmaceutical Corp A novel anti-c-met antibody and use thereof
MA49652A (fr) 2017-07-17 2020-05-27 Janssen Biotech Inc Régions de liaison à un antigène dirigées contre les domaines de la fibronectine de type iii et leurs procédés d'utilisation
CN109771642B (zh) 2017-11-13 2022-09-20 同济大学苏州研究院 c-MET激动型抗体及其用途
BR112021005585A2 (pt) * 2018-09-27 2021-06-29 Celgene Corporation proteínas de ligação a sirpa e métodos de uso das mesmas
US11591390B2 (en) 2018-09-27 2023-02-28 Celgene Corporation SIRP-α binding proteins and methods of use thereof
CN114340684A (zh) 2019-09-16 2022-04-12 瑞泽恩制药公司 用于免疫pet成像的放射性标记的met结合蛋白
CN117157325A (zh) 2021-04-08 2023-12-01 拜奥迪斯私人有限公司 抗c-met抗体和抗体-药物缀合物
WO2023034569A1 (en) * 2021-09-03 2023-03-09 Go Therapeutics, Inc. Anti-glyco-cmet antibodies and their uses

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
US5648273A (en) 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene
DE69315440T2 (de) 1992-09-18 1998-07-09 Us Gov Health & Human Serv Eine Methode zur Herstellung von Hepatozytwachstumsfaktor und eine Zelllinie
US6214344B1 (en) 1995-06-02 2001-04-10 Genetech, Inc. Hepatocyte growth factor receptor antagonists and uses thereof
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
IL127558A0 (en) 1996-07-03 1999-10-28 Genentech Inc Hepatocyte growth factor receptor agonists and uses thereof
ITMI20031127A1 (it) 2003-06-05 2004-12-06 Uni Degli Studi Del Piemont E Orientale Am Anticorpi anti-hgf-r e loro uso
CN100538364C (zh) * 2003-06-06 2009-09-09 健泰科生物技术公司 调节HGFβ链和C-MET的相互作用
HN2004000285A (es) 2003-08-04 2006-04-27 Pfizer Prod Inc ANTICUERPOS DIRIGIDOS A c-MET
KR100556660B1 (ko) * 2003-11-11 2006-03-10 국립암센터 Hgf의 중화가능 에피토프 및 이에 결합하는 중화 항체
EP2336178A1 (en) * 2003-12-11 2011-06-22 Genentech, Inc. Methods and compositions for inhibiting C-Met dimerization and activation
CN104804095A (zh) 2004-08-05 2015-07-29 健泰科生物技术公司 人源化抗c-met 拮抗剂
EP1957102B1 (en) 2005-11-16 2012-01-18 Fariba Nayeri Methods for inhibiting carcinogenesis and/or metastasis in an individual with endogenous c-met ligands and inhibitors
AU2007213804B2 (en) 2006-02-06 2012-12-13 Vertical Bio Ag Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products
CN101415730B (zh) 2006-03-30 2013-04-10 诺瓦提斯公司 c-Met抗体的组合物和使用方法
FR2906533B1 (fr) 2006-09-28 2013-02-22 Pf Medicament Procede de generation d'anticorps actifs contre un antigene de resistance,anticorps obtenus par ledit procede et leurs utilisations
EP2014681A1 (en) 2007-07-12 2009-01-14 Pierre Fabre Medicament Novel antibodies inhibiting c-met dimerization, and uses thereof
WO2009011426A1 (ja) 2007-07-19 2009-01-22 Eisai R & D Management Co., Ltd. γ-セクレターゼの新規基質c-Metを利用したスクリーニング方法
US7892770B2 (en) 2007-08-24 2011-02-22 Van Andel Research Institute Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods
IL198545A0 (en) 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
US8455623B2 (en) 2008-05-21 2013-06-04 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
WO2009145606A1 (en) 2008-05-28 2009-12-03 U-Protein Express B.V. Method for the production of proteins or protein fragments
GB2461546B (en) 2008-07-02 2010-07-07 Argen X Bv Antigen binding polypeptides
WO2010005965A1 (en) 2008-07-08 2010-01-14 Aronchick Craig A Colonic purgative formulations and methods of using the same
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
US8545839B2 (en) 2008-12-02 2013-10-01 Pierre Fabre Medicament Anti-c-Met antibody
AR074439A1 (es) 2008-12-02 2011-01-19 Pf Medicament Anticuerpo anti-cmet (receptor c-met)
AU2011325097B2 (en) 2010-11-03 2015-05-21 Argenx Bvba Anti c-Met antibodies

Also Published As

Publication number Publication date
US8637027B2 (en) 2014-01-28
EP2635603B1 (en) 2016-03-23
JP5857060B2 (ja) 2016-02-10
CA2816745A1 (en) 2012-05-10
RU2013125459A (ru) 2014-12-10
AU2015210420A1 (en) 2015-09-03
US20180215833A1 (en) 2018-08-02
CN103764678A (zh) 2014-04-30
US20120148607A1 (en) 2012-06-14
US9631027B2 (en) 2017-04-25
US9884917B2 (en) 2018-02-06
BR112013010688B1 (pt) 2020-11-17
IL226112B (en) 2019-05-30
US20140205606A1 (en) 2014-07-24
BR122014027420A2 (pt) 2019-08-20
BR112013010687A2 (pt) 2016-08-02
AU2011325098A1 (en) 2013-05-09
IL226113A0 (en) 2013-06-27
US9688773B2 (en) 2017-06-27
US20150376291A1 (en) 2015-12-31
ES2594493T3 (es) 2016-12-20
US20170349667A1 (en) 2017-12-07
DK2635602T3 (en) 2016-10-10
IL226112A0 (en) 2013-06-27
JP2013545738A (ja) 2013-12-26
EP2635602A1 (en) 2013-09-11
US20120156206A1 (en) 2012-06-21
AU2011325097A1 (en) 2013-05-02
EP2635603A1 (en) 2013-09-11
JP2013545455A (ja) 2013-12-26
US10676535B2 (en) 2020-06-09
US9688774B2 (en) 2017-06-27
WO2012059562A1 (en) 2012-05-10
AU2011325098B2 (en) 2016-07-14
CN103562223A (zh) 2014-02-05
RU2013125457A (ru) 2014-12-10
CN103562223B (zh) 2017-02-22
EP2635602B1 (en) 2016-09-07
CA2816919A1 (en) 2012-05-10
AU2011325097B2 (en) 2015-05-21
US20150376292A1 (en) 2015-12-31
EP3165538A1 (en) 2017-05-10
WO2012059561A1 (en) 2012-05-10
RU2608644C2 (ru) 2017-01-23
JP2016034957A (ja) 2016-03-17
AU2015210420B2 (en) 2017-08-03
CA2816745C (en) 2019-03-12

Similar Documents

Publication Publication Date Title
LTC2579894I2 (lt) CGRP antikūnai
BR112013010688A2 (pt) anticorpos anti c-met
BR112012030311A2 (pt) anticorpo
CO7020871A2 (es) Anticuerpos anti-il-36r
CO6811812A2 (es) Anticuerpo anti-b7-h3
DK2934584T3 (da) Anti-gdf15-antistoffer
DK2850101T3 (da) Anti-FcRn-antistoffer
DK2521736T3 (da) Humaniserede antistoffer
DK3284754T3 (da) Anti-cd38-antistoffer
BR112012028556A2 (pt) Indóis
DE102011100241A8 (de) Nitridhalbleiterbauteil
CR20130111A (es) Triazina-oxidiazoles
DE10170954T8 (de) Mikrowellendruckgarer
CR20140127A (es) Anticuerpo anti-abtcr
DE112011104226A5 (de) Käfigmutter
CO6791565A2 (es) Anticuerpos anti-notch1
DE102011117046A8 (de) Doppelkupplungswindungsgetriebe
DE112011101226A5 (de) Linearwegmesssystem
DE112011102080A5 (de) Kupplungszentralausrücker
DK2442899T3 (da) Rotorskive
DE102011002623A8 (de) Ventilsteuerzeitversteller
DK2828292T3 (da) Jcv-neutraliserende antistoffer
DE112011102711A5 (de) Hydrostataktor
DK2447426T3 (da) Vaske-WC
DK3521315T3 (da) Anti-transglutaminase-2-antistoffer

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25F Entry of change of name and/or headquarter and transfer of application, patent and certif. of addition of invention: change of name on requirement

Owner name: ARGEN-X BV (NL)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ARGEN-X N.V. (NL)

B25D Requested change of name of applicant approved

Owner name: ARGENX SE (NL)

B25A Requested transfer of rights approved

Owner name: ARGENX BVBA (BE)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/11/2011, OBSERVADAS AS CONDICOES LEGAIS.