BR112012009043A2 - imunoglobulinas de duplo domínio variável e sua utilização - Google Patents
imunoglobulinas de duplo domínio variável e sua utilizaçãoInfo
- Publication number
- BR112012009043A2 BR112012009043A2 BR112012009043A BR112012009043A BR112012009043A2 BR 112012009043 A2 BR112012009043 A2 BR 112012009043A2 BR 112012009043 A BR112012009043 A BR 112012009043A BR 112012009043 A BR112012009043 A BR 112012009043A BR 112012009043 A2 BR112012009043 A2 BR 112012009043A2
- Authority
- BR
- Brazil
- Prior art keywords
- double
- immunoglobulins
- domain variable
- domain
- variable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
munoglobulinas de duplo domínio variável e sua utilização. a presenten invenção se refere a proteínas ligantes multivalentes e multiespecíficas produzidas artificialmente, métodos de sua produção, e especificamente aos seus usos na prevenção, diagnóstico e/ou tratamento de doenças.
Applications Claiming Priority (2)
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US12/605,094 US20100260668A1 (en) | 2008-04-29 | 2009-10-23 | Dual Variable Domain Immunoglobulins and Uses Thereof |
PCT/US2010/053730 WO2011050262A2 (en) | 2009-10-23 | 2010-10-22 | Dual variable domain immunoglobulins and uses thereof |
Publications (1)
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BR112012009043A2 true BR112012009043A2 (pt) | 2015-09-08 |
Family
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BR112012009043A BR112012009043A2 (pt) | 2009-10-23 | 2010-10-22 | imunoglobulinas de duplo domínio variável e sua utilização |
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US (1) | US20100260668A1 (pt) |
EP (1) | EP2491129A4 (pt) |
JP (1) | JP2013507969A (pt) |
KR (1) | KR20130004563A (pt) |
CN (1) | CN102741423A (pt) |
AR (1) | AR078728A1 (pt) |
AU (1) | AU2010310565B2 (pt) |
BR (1) | BR112012009043A2 (pt) |
CA (1) | CA2778176A1 (pt) |
CL (1) | CL2012000980A1 (pt) |
CR (1) | CR20120267A (pt) |
DO (2) | DOP2012000117A (pt) |
EC (1) | ECSP12011911A (pt) |
IL (1) | IL219205A0 (pt) |
MX (1) | MX2012004775A (pt) |
PE (1) | PE20121249A1 (pt) |
RU (1) | RU2012121189A (pt) |
TW (1) | TW201127956A (pt) |
UY (1) | UY32965A (pt) |
WO (1) | WO2011050262A2 (pt) |
ZA (1) | ZA201203688B (pt) |
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-
2009
- 2009-10-23 US US12/605,094 patent/US20100260668A1/en not_active Abandoned
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2010
- 2010-10-22 AR ARP100103871A patent/AR078728A1/es unknown
- 2010-10-22 TW TW099136250A patent/TW201127956A/zh unknown
- 2010-10-22 AU AU2010310565A patent/AU2010310565B2/en not_active Ceased
- 2010-10-22 JP JP2012535410A patent/JP2013507969A/ja not_active Withdrawn
- 2010-10-22 EP EP10825739.5A patent/EP2491129A4/en not_active Withdrawn
- 2010-10-22 UY UY0001032965A patent/UY32965A/es not_active Application Discontinuation
- 2010-10-22 WO PCT/US2010/053730 patent/WO2011050262A2/en active Application Filing
- 2010-10-22 MX MX2012004775A patent/MX2012004775A/es active IP Right Grant
- 2010-10-22 BR BR112012009043A patent/BR112012009043A2/pt not_active IP Right Cessation
- 2010-10-22 CA CA2778176A patent/CA2778176A1/en not_active Abandoned
- 2010-10-22 RU RU2012121189/10A patent/RU2012121189A/ru not_active Application Discontinuation
- 2010-10-22 KR KR1020127013242A patent/KR20130004563A/ko not_active Application Discontinuation
- 2010-10-22 PE PE2012000522A patent/PE20121249A1/es not_active Application Discontinuation
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- 2012-04-26 DO DO2012000122A patent/DOP2012000122A/es unknown
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WO2011050262A2 (en) | 2011-04-28 |
CR20120267A (es) | 2012-08-14 |
PE20121249A1 (es) | 2012-10-06 |
JP2013507969A (ja) | 2013-03-07 |
DOP2012000122A (es) | 2013-09-15 |
CN102741423A (zh) | 2012-10-17 |
TW201127956A (en) | 2011-08-16 |
RU2012121189A (ru) | 2013-11-27 |
ECSP12011911A (es) | 2012-07-31 |
MX2012004775A (es) | 2012-06-01 |
US20100260668A1 (en) | 2010-10-14 |
KR20130004563A (ko) | 2013-01-11 |
AR078728A1 (es) | 2011-11-30 |
CA2778176A1 (en) | 2011-04-28 |
CL2012000980A1 (es) | 2013-01-11 |
UY32965A (es) | 2011-02-28 |
AU2010310565A1 (en) | 2012-05-31 |
EP2491129A4 (en) | 2013-05-29 |
DOP2012000117A (es) | 2012-07-31 |
AU2010310565B2 (en) | 2013-05-23 |
EP2491129A2 (en) | 2012-08-29 |
IL219205A0 (en) | 2012-06-28 |
ZA201203688B (en) | 2014-12-23 |
WO2011050262A3 (en) | 2011-06-30 |
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