BR0214275A - Dispositivo tendo propriedades osteocondutora e osteoindutora - Google Patents
Dispositivo tendo propriedades osteocondutora e osteoindutoraInfo
- Publication number
- BR0214275A BR0214275A BR0214275-9A BR0214275A BR0214275A BR 0214275 A BR0214275 A BR 0214275A BR 0214275 A BR0214275 A BR 0214275A BR 0214275 A BR0214275 A BR 0214275A
- Authority
- BR
- Brazil
- Prior art keywords
- relates
- osteoinductive
- treatment
- osteoconductive
- properties
- Prior art date
Links
- 230000002138 osteoinductive effect Effects 0.000 title abstract 4
- 230000000278 osteoconductive effect Effects 0.000 title abstract 3
- 210000000988 bone and bone Anatomy 0.000 abstract 3
- 238000001727 in vivo Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000003416 augmentation Effects 0.000 abstract 1
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 235000011010 calcium phosphates Nutrition 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 230000023753 dehiscence Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003028 elevating effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000472 traumatic effect Effects 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/108—Specific proteins or polypeptides not covered by groups A61L24/102 - A61L24/106
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Glass Compositions (AREA)
- Apparatuses And Processes For Manufacturing Resistors (AREA)
- Permanent Magnet Type Synchronous Machine (AREA)
- Dental Preparations (AREA)
- Prostheses (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"DISPOSITIVO TENDO PROPRIEDADES OSTEOCONDUTORA E OSTEOINDUTORA". A presente invenção refere-se a um dispositivo tendo propriedades osteoindutora e osteocondutora in vivo compreendendo um veículo contendo fosfato de cálcio e uma proteína osteoindutora, onde o dito veículo é homogeneamente revestido com a dita proteína. Além disso, a presente invenção refere-se a um método para a produção de um dispositivo tendo propriedades osteoindutora e osteocondutora in vivo. A invenção compreende uma composição farmacêutica compreendendo o dispositivo da invenção ou um dispositivo que pode ser obtido através do método da invenção e refere-se ao uso do dito dispositivo para a preparação de uma composição farmacêutica a ser usada para aumento de osso, para tratamento de defeitos de osso, para tratamento de doença do disco degenerativa e traumática, para o tratamento de deiscência do osso ou para ser usada para elevação do assoalho do seio. Finalmente, a invenção refere-se a um kit compreendendo o dispositivo da invenção ou um dispositivo que pode ser obtido através do método da invenção.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01127573 | 2001-11-19 | ||
PCT/EP2002/003463 WO2003043673A1 (en) | 2001-11-19 | 2002-03-27 | Device having osteoinductive and osteoconductive properties |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0214275A true BR0214275A (pt) | 2004-09-21 |
Family
ID=8179288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0214275-9A BR0214275A (pt) | 2001-11-19 | 2002-03-27 | Dispositivo tendo propriedades osteocondutora e osteoindutora |
Country Status (16)
Country | Link |
---|---|
US (2) | US8546334B2 (pt) |
EP (1) | EP1448246B2 (pt) |
JP (2) | JP4473576B2 (pt) |
CN (1) | CN100425285C (pt) |
AT (1) | ATE303169T1 (pt) |
AU (1) | AU2002308204B9 (pt) |
BR (1) | BR0214275A (pt) |
CA (1) | CA2466947C (pt) |
CY (1) | CY1105664T1 (pt) |
DE (1) | DE60205937T3 (pt) |
DK (1) | DK1448246T4 (pt) |
ES (1) | ES2247423T5 (pt) |
HK (1) | HK1071315A1 (pt) |
PT (1) | PT1448246E (pt) |
SI (1) | SI1448246T2 (pt) |
WO (1) | WO2003043673A1 (pt) |
Families Citing this family (21)
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CA2558395C (en) * | 2004-03-10 | 2011-11-29 | Scil Technology Gmbh | Coated implants, their manufacturing and use thereof |
EP1604693A1 (en) | 2004-06-09 | 2005-12-14 | Scil Technology GmbH | In situ forming scaffold, its manufacturing and use |
EP1604694A1 (en) * | 2004-06-09 | 2005-12-14 | Scil Technology GmbH | Composite device having osteoinductive and osteoconductive properties |
US20100112028A1 (en) * | 2004-06-09 | 2010-05-06 | Klaus Hellerbrand | Composite material for use as protein carrier |
US20060286171A1 (en) * | 2005-06-17 | 2006-12-21 | Tianhong Zhou | Bone morphogenetic protein formulations |
WO2007068489A2 (en) * | 2005-12-14 | 2007-06-21 | Scil Technology Gmbh | A moldable biomaterial for bone regeneration |
US20070299520A1 (en) * | 2006-06-26 | 2007-12-27 | Warsaw Orthopedic, Inc. | Surface treatment of implantable devices |
AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
DE102006060958A1 (de) | 2006-12-20 | 2008-06-26 | Jennissen, Herbert P., Prof. Dr. | Verfahren zur Herstellung einer Polymermatrix, daraus bestehende Implantate sowie deren Verwendung |
US20080221681A1 (en) * | 2007-03-09 | 2008-09-11 | Warsaw Orthopedic, Inc. | Methods for Improving Fatigue Performance of Implants With Osteointegrating Coatings |
US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
US8058237B2 (en) * | 2007-08-07 | 2011-11-15 | Advanced Technologies & Regenerative Medicine, LLC | Stable composition of GDF-5 and method of storage |
US20090061002A1 (en) * | 2007-09-05 | 2009-03-05 | Venbrocks Rudolf A | Calcium phospate based delivery of growth and differentiation factors to compromised bone |
DE102007051914A1 (de) * | 2007-10-29 | 2009-05-07 | Herbert Prof. Dr. Jennissen | Verfahren zur Herstellung von mit Wachstumsfaktoren beladenen Partikeln sowie die so erhaltenen Partikel |
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US20110059149A1 (en) * | 2008-06-16 | 2011-03-10 | Little Marisa A | Process for depositing calcium phosphate therapeutic coatings with different release rates and a prosthesis coated via the process |
CN102448505B (zh) * | 2009-05-28 | 2015-04-15 | 埃得生物公司 | 多层蛋白质膜、制造方法以及使用该膜的药物递送装置和生物医学植入物 |
US20130122066A1 (en) * | 2010-07-30 | 2013-05-16 | Biopham Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Drug delivery devices and growth factor formulations for accelerated wound healing |
WO2012093939A1 (en) | 2011-01-05 | 2012-07-12 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | Particles comprising calcium phosphate and use thereof |
EP3682931A1 (en) * | 2019-01-21 | 2020-07-22 | Universitätsklinikum Hamburg-Eppendorf | Thoracic catheter |
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2002
- 2002-03-27 AT AT02803343T patent/ATE303169T1/de active
- 2002-03-27 BR BR0214275-9A patent/BR0214275A/pt not_active IP Right Cessation
- 2002-03-27 ES ES02803343.9T patent/ES2247423T5/es not_active Expired - Lifetime
- 2002-03-27 WO PCT/EP2002/003463 patent/WO2003043673A1/en active IP Right Grant
- 2002-03-27 DK DK02803343.9T patent/DK1448246T4/en active
- 2002-03-27 AU AU2002308204A patent/AU2002308204B9/en not_active Ceased
- 2002-03-27 PT PT02803343T patent/PT1448246E/pt unknown
- 2002-03-27 US US10/496,399 patent/US8546334B2/en not_active Expired - Fee Related
- 2002-03-27 SI SI200230206T patent/SI1448246T2/sl unknown
- 2002-03-27 EP EP02803343.9A patent/EP1448246B2/en not_active Expired - Lifetime
- 2002-03-27 CN CNB028192745A patent/CN100425285C/zh not_active Expired - Fee Related
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- 2002-03-27 JP JP2003545351A patent/JP4473576B2/ja not_active Expired - Fee Related
- 2002-03-27 DE DE60205937.2T patent/DE60205937T3/de not_active Expired - Lifetime
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Also Published As
Publication number | Publication date |
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SI1448246T2 (sl) | 2015-12-31 |
EP1448246A1 (en) | 2004-08-25 |
CA2466947C (en) | 2012-05-22 |
SI1448246T1 (sl) | 2005-12-31 |
EP1448246B2 (en) | 2015-09-09 |
US20060088565A1 (en) | 2006-04-27 |
ES2247423T5 (es) | 2015-12-30 |
WO2003043673A1 (en) | 2003-05-30 |
PT1448246E (pt) | 2005-11-30 |
JP2010075737A (ja) | 2010-04-08 |
ES2247423T3 (es) | 2006-03-01 |
AU2002308204B9 (en) | 2008-06-12 |
DK1448246T4 (en) | 2015-12-21 |
DE60205937D1 (de) | 2005-10-06 |
AU2002308204A1 (en) | 2003-06-10 |
EP1448246B1 (en) | 2005-08-31 |
CA2466947A1 (en) | 2003-05-30 |
ATE303169T1 (de) | 2005-09-15 |
CN100425285C (zh) | 2008-10-15 |
JP5054091B2 (ja) | 2012-10-24 |
DE60205937T3 (de) | 2016-01-21 |
JP2005509494A (ja) | 2005-04-14 |
HK1071315A1 (en) | 2005-07-15 |
DK1448246T3 (da) | 2005-12-27 |
CN1561235A (zh) | 2005-01-05 |
JP4473576B2 (ja) | 2010-06-02 |
AU2002308204B2 (en) | 2007-09-27 |
CY1105664T1 (el) | 2010-12-22 |
US8546334B2 (en) | 2013-10-01 |
US20150080303A1 (en) | 2015-03-19 |
DE60205937T2 (de) | 2006-06-14 |
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